Clinical trials: Resorption
Implant, Analgesia
Low Level Laser (LED) Use to Increase Dental Implant Stability and Post Operative Analgesia
Study hypothesis: Low level laser (LED) will reduce initial bone resorption and improve primary stability of dental implant. It will also reduces post operative pain compared to patient without treatment Implant osseointegration…
- Trial name
- NCT01097499
- Testing
- OsseoPulse device (Light emitting diode technology)
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Soft Tissue Augmentation
Acellular Dermal Matrix Versus Tenting Technique in Peri-implant Soft Tissue Augmentation and Crestal Bone Stability
This study looks at two ways to make gums thicker and bones stable around dental implants for people with thin gums. It compares two methods in 40 people: one method uses a special graft, and the other uses a technique called…
- Trial name
- NCT06302387
- Testing
- Acellular Dermal Matrix, Soft Tissue Expansion using Tenting Technique
- Where
- Lithuania
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Alveolar Bone Loss, Periodontitis
Zirconia Vs Titanium Implants in Deficient Ridges
The aim of this study is to evaluate clinically and radiographically soft tissue around single-implant crowns and peri-implant bone resorption respectively by using zirconia implants or titanium implants in horizontally deficient…
- Trial name
- NCT04375839
- Testing
- Zirconia implant, Titanium implant
- Where
- India
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- SVS Institute of Dental Sciences
Malocclusion; Displaced Teeth
3-D Evaluation of Alveolar Bone Changes and Root Resorption After Traction of Buccally Displaced Maxillary Canines
This clinical study used CBCT images to investigate the alveolar bone changes and root resorption in unilateral buccally displaced maxillary canines and adjacent teeth before and after orthodontic traction of unilateral BDMCs.
- Trial name
- BDMC (NCT07399197)
- Testing
- T-loop, Piggyback double wire
- Where
- Yemen
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sana'a University
Soft Tissue, Dental Implants
Xenogenic Bone Intentionally Left Exposed
The goal of this clinical trial is to compare, the effect of letting the xenogeneic bone graft exposed to the oral environment or seal off the graft with a collagen matrix.
- Conditions
- Soft Tissue, Dental Implants, Healing Wound
- Trial name
- NCT06191510
- Testing
- Bio-Oss Exposed, Mucograft Exposed
- Where
- Brazil
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Alveolar Bone Resorption, Graft Overgrowth
Histological and Volumetric Evaluation of Customized Allograft Bone Blocks
Customized bone blocks need CBCT and digital software to design the block needed to rehabilitate. Some advantages are reduced surgical time and better adaptation of the graft, leading to less complications.
- Conditions
- Alveolar Bone Resorption, Graft Overgrowth, Resorption of Bone Graft, Graft Complication
- Trial name
- NCT05937035
- Testing
- Customized allogenic bone block surgery
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Orthodontic Pathological Resorption of External Root, Orthodontic Appliance Complication
Photobiomodulation and Root Resorption
Objectives: The aim of this study is to investigate the effect of photobiomodulation therapies on root resorption compared with the placebo group. Materials and Methods: 30 patients, who were admitted to the ………….
- Conditions
- Orthodontic Pathological Resorption of External Root, Orthodontic Appliance Complication, Orthodontic Tooth Movement
- Trial name
- NCT04044989
- Testing
- Laser, light-emitting diode (LED)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Bone Loss, Alveolar
Evaluation of Regenerative Potential in Horizontal Bone Loss Using VCMX Along With LASER Therapy
Background- Periodontitis, an inflammatory disease of the periodontium, is one of the major causes of tooth mortality. Of all the bone destruction patterns that are present in periodontitis, horizontal bone loss is the most…
- Trial name
- NCT06204588
- Testing
- control group: SFA only, Test group 1: VCMX + Low level LASER therapy + Single flap approach, Test group 2: Low level LASER therapy + Single flap approach
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periodontitis
Impact of SRP on Bone Resorption and Systemic Inflammatory Markers in Postmenopausal Women With Periodontitis
This study is designed to determine the effect of treating postmenopausal women and using non-surgical techniques on biomarkers of systemic inflammation (IL-6 ) and systemic bone resorption (C-terminal collagen cross-links, CTX).
- Trial name
- NCT04261491
- Testing
- scaling and root planing
- Where
- 2 sites in India
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Healthy, Adult
Understanding Effects of Calcium on the Gut-Bone Axis
The study team is inviting 13 healthy people to complete a study to explore how calcium affects hormones and bones after eating. Participants will be asked to complete two study visits within eight weeks.
- Conditions
- Healthy, Adult, Calcium, Bone Resorption
- Trial name
- NCT06383117
- Testing
- Calcium carbonate
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Periodontal Diseases, Hyperuricemia
Evaluation of the Effect of Hyperuricemia on Alveolar Bone Loss
Periodontitis is a multifactorial disease characterized by chronic inflammation of the gum tissue and alveolar bone destruction, and is known to be associated with various systemic diseases.
- Conditions
- Periodontal Diseases, Hyperuricemia, Oxidative Stress
- Trial name
- NCT07666126
- Testing
- Collection of gingival crevicular fluid (GCF) and serum samples, Measurement of periodontal clinical parameters
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Alveolar Bone Loss, Chronic Periodontitis, Lovestatin Gel, Regeneration
The Effect of Lovastatin Gel in the Treatment of Chronic Periodontitis
Aim: dis double-blind split-mouth clinical trial study was performed to evaluate teh clinical and radiographic effect of local delivery of lovastatin gel as an adjunct to scaling and root planning (SRP) in teh treatment of…
- Trial name
- NCT03178526
- Testing
- Lovastatin gel
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Periodontal Bone Loss, Periodontal Pocket
Treatment of Intraosseous Periodontal Defects With Amelogenins
The aim of the present investigation will be evaluate the healing of periodontal intraosseous defects following Minimally Invasive Non Surgical Debridement (MINSD) and application of amelogenins, compared to MINSD alone.
- Trial name
- NCT05315804
- Testing
- MINSD and amelogenins, MINSD
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Federico II University
Bone Loss, Energy Supply; Deficiency
Cycling Duration and Bone Markers in in Active Young Adults
Exercise is an important factor in bone health. Sclerostin is one of the key molecules involved in bone response to mechanical loading.
- Trial name
- NCT04380155
- Testing
- Exercise
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brock University
External Apical Root Resorption in Maxillary Canines During Orthodontic Retraction
Comparison of Root Resorption in Modified Corticotomy-Assisted and Conventional Canine Retraction
This randomized controlled clinical trial will compare external apical root resorption in patients undergoing maxillary canine retraction using modified corticotomy-assisted frictionless T-loop mechanics versus conventional…
- Trial name
- MCA-CR (NCT07458139)
- Testing
- Modified Corticotomy assisted frictionless canine retraction, Conventional Frictionless Canine retraction
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Islamabad Medical and Dental College
Alveolar Bone Loss
Alveolar Bone Loss Around 3 Different Designs of Dental Implant: Prospective Comparative Clinical Trail
comparison of alveolar bone resorbtion/ changes for a period of 12 month post loading of different designs and brands of oral implants.
- Trial name
- NCT00544323
- Testing
- oral implant
- Where
- Israel
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Marginal Bone Levels, Open Sinus Elevation
Marginal Bone Changes Around Dental Implant Placed With Open vs. Closed Sinus Elevation
Background: In cases with atrophic posterior maxilla, sinus elevation techniques are essential for a successful implant placement.
- Conditions
- Marginal Bone Levels, Open Sinus Elevation, Closed Sinus Elevation
- Trial name
- NCT06811337
- Testing
- Open Sinus Elevation, Closed Sinus Elevation
- Where
- Egypt
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Misr International University
Bone Resorption
Dietary Intake Modifications to Protect Against Changes in Bone Metabolism
Bone loss is not only a well-documented effect of spaceflight on astronauts, but also a condition that affects millions of men and women on Earth each year.
- Trial name
- ProK (NCT01713634)
- Testing
- Preflight, In-flight
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- National Aeronautics and Space Administration (NASA)
Root Resorption
Repair of Orthodontically-induced Tooth Root Resorption by Ultrasound
Tooth-root resorption, also known as shortening or erosion,(TRR) is one of the adverse outcomes of dental trauma, orthodontic tooth movement and dental replantation/transplantation.
- Trial name
- NCT00423956
- Testing
- Repairing Induced tooth root resorption by ultrasound
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Implant Tissue Failure
Effects of ABO Blood Types on the Survival and Marginal Bone Resorption of Dental Implants
This study evaluates implant survival and marginal bone resorption in patients receiving implant treatment with respect to demographic data and AB0 (groups) blood types.
- Trial name
- NCT04054271
- Where
- Turkey (Türkiye)
- Volunteers
- 963 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University