Clinical trials: Resorption
Periodontal Inflammation, Alveolar Bone Loss
The Effect of Non-surgical Periodontal Treatment on Dickkoff-1 and Secreted Frizzled Related Protein-5 Levels
Periodontitis is a condition that is defined by microbial-associated, host-induced inflammation, which ultimately results in the loss of periodontal attachment.Periodontal clinical parameters are the most reliable indicators of…
- Conditions
- Periodontal Inflammation, Alveolar Bone Loss, Periodontal Diseases
- Trial name
- NCT06727929
- Testing
- Collection of gingival crevicular fluid, ELISA
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Alveolar Bone Resorption, Alveolar Ridge Enlargement
Modified Ridge Splitting Technique Using Autogenous Bone Blocks (MRS)
In this clinical study ridge splitting procedures are preformed using autogenous bone blocks. After a 3-month healing, at the time of dental implant placement bone core biopsy samples are harvested.
- Trial name
- MRS (NCT05005858)
- Testing
- Alveolar ridge splitting, Creating osteotomies with piezoelectric device
- Where
- Hungary
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Atrophic Maxilla
Comparing Resin and Metallic Surgical Guides for Zygomatic Implants in Patients With Severe Upper Jaw Bone Loss
Oral rehabilitation with dental implants in patients with severely atrophic maxillae often presents significant surgical challenges.
- Trial name
- NCT07912658
- Testing
- resin guide group, metal guide group
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Cleft
Partial Maxillary Expansion With Post Grafting Expansion vs. Pre Full Maxillary Expansion in Secondary Alveolar Cleft
Intermediate grafting with both pre- and post- grafting maxillary expansion with time span after grafting 6-8 weeks for consolidation and final retention for 3 months after finalization of expansion will get the advantages of…
- Trial name
- NCT05941988
- Testing
- pre grafting partial maxillary expansion with post grafting expansion
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Loss, Posterior Mandible
Khoury's Bone Shell Technique Versus Titanium-Reinforced Polytetrafluoroethylene for Augmentation of Horizontal Deficiency in Posterior Mandible (Histomorphometry Analysis)
The purpose of the study is the comparison of bone gained histologically from the Bone Shell Khoury's Technique in comparison with the usage of non-resorbable membrane polytetrafluoroethylene and discussing its eligibility for…
- Trial name
- NCT07669792
- Testing
- GBR using Ti based PTFE, Bone Shell Khoury's Technique
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Poly(Lactide-co-glycolide) Sutures, Suture Resorption
Comparative Analysis of fast-and Slow-absorbable Poly(Lactose-co-glycolide) Sutures in Oral Surgery: a Randomized Controlled Trial.
This study aims to compare slow-resorbing and fast-resorbing sutures used after the surgical extraction of lower third molars. Sutures are routinely placed after wisdom tooth removal to promote hemostasis.
- Conditions
- Poly(Lactide-co-glycolide) Sutures, Suture Resorption, Third Molar Surgery
- Trial name
- NCT07498361
- Testing
- Fast absorbable sutures application, Standard absorbable sutures application
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Padova, School of Dental Medicine
Bone Resorption
GBR and Autogenous Bone Chips
This study will be an open, prospective, split-mouth, randomised controlled clinical trial. A total of 14 patients searching for oral implant treatment and where a GBR procedure is indicated per implant treatment will be…
- Trial name
- NCT03946020
- Testing
- Guided bone regeneration with or without autologous bone
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Alveolar Bone Loss
Evaluation of Autogenous Stored Versus Autogenous Fresh Mineralized Dentin Graft for Alveolar Ridge Preservation
Tooth extraction triggers a cascade of biological events mediated by both the local inflammatory response that follows the surgical intervention and the deprivation of masticatory stimulation of the periodontium, which elicit an…
- Trial name
- NCT05536479
- Testing
- Autogenous stored mineralized dentin graft (ASMDG), Autogenous fresh mineralized dentin graft (AFMDG)
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Crowding of Anterior Maxillary Teeth, Crowding of Anterior Mandibular Teeth
Comparing Labial and Lingual Orthodontic Appliances on Root Resorption and Bone Height
Patients who have moderate crowding that could be treated on a non-extraction will be treated in this study. The apical root resorption and alveolar bone height of the lingual and labial fixed appliances will be assessed.
- Trial name
- NCT06401369
- Testing
- Lingual brackets, Buccal brackets
- Where
- Syria
- Volunteers
- 40 people
- Sponsor
- Damascus University
Alveolar Bone Loss, Maxillary Sinus Disease
Efficacy of Bioactive Glass vs. Xenograft in Maxillary Sinus Augmentation
This randomized controlled study aims to evaluate the clinical, radiographic, and histologic efficacy of using bioactive glass bone graft (UNIGRAFT by Biomed Inc., USA) compared to a conventional xenograft in maxillary sinus…
- Conditions
- Alveolar Bone Loss, Maxillary Sinus Disease, Tooth Loss
- Trial name
- BIOXENO (NCT07125846)
- Testing
- Bioactive Glass Bone Graft (UNIGRAFT), Xenograft Bone Graft (Bio-Oss)
- Volunteers
- 20 people
- Sponsor
- Suez Canal University
Tooth Loss, Alveolar Ridge Resorption After Extraction
BMP Effect on Implant Stability and Marginal Bone Level After Immediate Placement
This randomized controlled clinical trial aims to evaluate the effect of recombinant human Bone Morphogenetic Protein-2 (rhBMP-2) on the stability and marginal bone level of dental implants following immediate placement.
- Conditions
- Tooth Loss, Alveolar Ridge Resorption After Extraction, Tooth Extraction
- Trial name
- NCT07240493
- Testing
- rhBMP-2 placement, conventional immediate implant
- Where
- Iraq
- Volunteers
- 24 people
- Sponsor
- Aya Adil Saeed
Alveolar Bone Resorption, Dental Implant Failure Nos
Artificial Intelligence/Computer Guided Ridge Splitting for Treating Horizontal Ridge Defects
Aim of the current randomized clinical trial is to evaluate and compare the effectiveness of computer-guided ridge splitting approach assisted by artificial intelligence versus conventional approach combined with simultaneous…
- Trial name
- NCT06135506
- Testing
- free-hand ridge splitting, AI/guided ridge splitting
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Missing Teeth
Evaluation of the Abutment Type Following Oral Implants in Terms of the Surrounding Bone Height
Compare two different types of abutments (molded abutments and computer-designed 3D printed abutments) in terms of the amount of bone loss, and depth of periodontal pockets around the implant during different periods.
- Trial name
- NCT05350293
- Testing
- Molded abutment, 3D printed abutment
- Where
- Syria
- Volunteers
- 32 people
- Sponsor
- Damascus University
Periodontal Bone Loss
Decortication With Calcium Phosphosilicate Putty in the Treatment of Non-contained Intrabony Periodontal Defects
To overcome the disadvantage of complex morphology and availability of less favorable support to retention of graft and clot stabilization in 1-, 1-2-wall periodontal defects, it was hypothesized that placement of CPS putty…
- Trial name
- NCT03435757
- Testing
- OFD+IMP+CPS, OFD+IMP
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Speed of Alignment, Pain
Comparison of Alignment Speed, Patient Discomfort and Root Resorption Between Two Different Sequences of Archwires
In this Clinical trial we aim to compare alignment speed, patient discomfort and root resorption between two different sequences of NiTi archwires
- Conditions
- Speed of Alignment, Pain, External Root Resorption
- Trial name
- NCT07758556
- Testing
- Archwire
- Where
- 3 sites in Pakistan
- Volunteers
- 60 people
- Sponsor
- Foundation University Islamabad
Arthroplasty Complications
Osteolysis Development Around Uncemented Cups With or Without Screw Holes
In order to investigate the role of acetabular cup screw holes for the transport of osteolysis-inducing particles in a total hip arthroplasty articulation, the investigators compare the amount of bone loss around acetabular cups…
- Trial name
- NCT03692351
- Testing
- Uncemented acetabular cup with screw holes, Uncemented acetabular cup without screw holes
- Volunteers
- 95 people
- Sponsor
- Sahlgrenska University Hospital
Bone Atrophy, Alveolar
Comparative Study Between Autogenous Bone Block and Tent Pole Technique for Augmentation of Atrophic Anterior Maxilla
The goal of this clinical trial is to compare in patients with atrophied anterior maxilla, bone augmentation techniques ( gold standard bone block and tent pole technique).
- Trial name
- NCT06125938
- Testing
- tent pole technique, Autogenous bone block technique
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bone Loss
The Prevention Of Postmenopausal Osteoporosis With Lasofoxifene And Cytokine Evaluation
The objective of the study is to demonstrate the effects that lasofoxifene has on serum markers of bone metabolism.
- Trial name
- LACE (NCT00674453)
- Testing
- Lasofoxifene
- Where
- United Kingdom
- Volunteers
- 51 people
- Sponsor
- Ligand Pharmaceuticals
Cosmetic Techniques, Mammaplasty
Volumetric Study of Fat Resorption After Breast Lipofilling
Prospective observational study to evaluate effects on washing to improve viability of fat grafts in breast lipofilling.
- Trial name
- Lipofilling (NCT03016663)
- Testing
- Technique of Breast Lipofilling
- Where
- Malaysia
- Volunteers
- 10 people
- Sponsor
- University of Malaya
Breast Cancer, Prostate Cancer
Study to Evaluate the Safety and Effects AZD0530 on Prostate and Breast Cancer Subjects With Metastatic Bone Disease
The purpose of this study is to determine the effect of AZD0530 on subjects with breast cancer or prostate cancer with metastatic bone disease in comparison to zoledronic acid.
- Conditions
- Breast Cancer, Prostate Cancer, Bone Neoplasms
- Trial name
- NCT00558272
- Testing
- AZD0530, Zoledronic Acid
- Where
- 28 sites in United States, Canada and 6 more
- Volunteers
- 139 people
- Sponsor
- AstraZeneca