Clinical trials: Resorption
Class III Malocclusion, Root Resorption
Determining the Presence of RAP in Orthognathic Patients and Its Effect on Root Resorption by Biomarkers
A prospective clinical trial to what extent inflammatory biomarkers are affected by the medication after orthognathic surgery in early surgical cases and whether these biomarkers affects the amount of maxillary or mandibular…
- Trial name
- RAP (NCT04823325)
- Testing
- Orthognathic Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Ridge Preservation, Post Extraction Alveolar Bone Resorption
Socket Preservation Technique Using Bovine Bone, Platelet Rich Fibrin Or A Combination Of Both: A Clinical, Radiographic And Histological Assesment At 4 Months
Post extraction alveolar bone resorption is one of the main challenges that face oral implantologists in their daily surgical practice (1).
- Trial name
- NCT05889377
- Testing
- Socket preservation
- Where
- Lebanon
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Bone Loss, Alveolar
Tenting Screws in Combination With Platelet Concentrate for Vertical Alveolar Ridge Augmentation
Alveolar bone resorption often occurs after tooth extraction. At present, guided bone regeneration technique is widely used in clinic since it leads to less trauma and less complications.
- Trial name
- NCT04835532
- Testing
- guided bone gereration
- Where
- China
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Orthodontic Tooth Movement, Intrusion of Tooth
Evaluation of Root Resorption Following Different Mandibular Incisors Intrusive Mechanics
Evaluation of root resorption following different mandibular incisors intrusive mechanics : A randomized clinical trial
- Conditions
- Orthodontic Tooth Movement, Intrusion of Tooth, Resorption, Root
- Trial name
- NCT05414019
- Testing
- Mini-screw, Utility arch, Nitinol reverse curve wire
- Where
- Egypt
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Prosthodontics, Implants, Dental
Effect of PEEK and Titanium Framework Reinforcement on Marginal Bone Loss Around Implants Supporting a Fixed All-on-four Prosthesis in Completely Edentulous Mandibles
A fixed all-on-four prosthesis will be constructed for the lower arch for each patient and the marginal bone loss will be evaluated at baseline, 3,6,9 and 12 months.
- Conditions
- Prosthodontics, Implants, Dental, Prosthesis, Bone Loss, Alveolar
- Trial name
- NCT07475507
- Testing
- Titanium framework reinforced all on four prosthesis, PEEK framework reinforced all on four prosthesis
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bariatric Surgery Candidate, Bone Loss
Healthy Body, Healthy Bones After Bariatric Surgery Trial
One in three adults in the United States suffers from obesity. Bariatric surgery is an increasingly utilized and effective treatment for obesity and obesity-related comorbidities, however, the massive weight loss associated with…
- Conditions
- Bariatric Surgery Candidate, Bone Loss, Bone Resorption
- Trial name
- NCT04279392
- Testing
- Zoledronic Acid 5 mg/Bag 100 ml Inj
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Deep Overbite
Evaluation of Root Resorption During the Correction of Deep Bite With the Help of Laser Irradiation
This study aims to investigate the effectiveness of low-level laser in reducing the resorption of the roots of the upper incisors.
- Trial name
- NCT05734092
- Testing
- Traditional orthodontic treatment, Low-Level Laser
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Damascus University
Alveolar Bone Loss
Dimensional Changes in Alveolar Ridge Preservation
Objective: The objective is to evaluate the dimensional changes of soft tissue and alveolar ridge after extraction of posterior elements with different clinical protocols of alveolar preservation.
- Trial name
- NCT06081296
- Testing
- Control group, Mixed free gingival graft group, Bone+ mixed free gingival graft group
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Renato Casarin
Loss of Teeth Due to Extraction, Alveolar Bone Loss
Regeneration of Alveolar Sockets With rhBMP-2-loaded Bovine Bone Mineral
Aim of the present investigation will be to evaluate the efficacy and safety of a granulate of rhBMP-2- loaded bovine bone mineral (rhBMP-2-BBM) as alveolar bone regeneration procedure following tooth extraction.
- Conditions
- Loss of Teeth Due to Extraction, Alveolar Bone Loss, Edentulous Alveolar Ridge
- Trial name
- PROTEOGRAFT (NCT05717478)
- Testing
- rhBMP-2-BBM, Bio-Oss+Bio-Gide
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Complutense de Madrid
Alveolar Bone Loss
Densah Burs vs. Electrical Mallet in Closed Sinus Lifting.
The aim of the comparative study is to evaluate the density and amount of new bone formed (bone height gain)around dental implant placed simultaneously in posterior maxilla after closed sinus floor elevation using…
- Trial name
- NCT06180187
- Testing
- Electrical mallet, Osseo-densification burs
- Volunteers
- 50 people
- Sponsor
- Fayoum University
Healing Wound, Alveolar; Wound
Ultrasound for Socket Healing Evaluation
The design is a single blinded, dual comparative study of ultrasound versus micro-CT/LASCA in one study group. Up to a total of 140 subjects registered will be recruited.
- Conditions
- Healing Wound, Alveolar; Wound, Alveolar Bone Loss, Image
- Trial name
- NCT06017193
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Bone Loss, Alveolar
Short Dental Implants (5 mm) Versus Long Dental Implants (10 mm)
The purpose of this study is to evaluate the survival rate of 5 mm short implants compared to longer implants (10 mm) placed in sinus-grafted sites.
- Trial name
- NCT04144322
- Testing
- Zimmer T3 Short Ex Hex With Discrete Crystalline Deposition, Zimmer T3 with Discrete Crystalline Deposition Ex Hex Parallel Walled implants
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Alveolar Bone Loss, Peri-Implantitis
Radiological Bone Loss on Different Levels of Dental Implants
One of the criteria used for long-term implant success is the evaluation of radiographic bone loss. It is known that the keratinized mucosa over the alveolar crest forms a protective barrier against inflammatory infiltration.
- Conditions
- Alveolar Bone Loss, Peri-Implantitis, Bone Loss in Jaw
- Trial name
- NCT05595746
- Testing
- dental implant placement
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Osteopenia, Osteoporosis
Prevention of Bone Loss After Pediatric Hematopoietic Cell Transplantation
This is a Phase 2, open-label, randomized, controlled clinical study of pediatric subjects treated with pamidronate with calcium and vitamin D versus calcium and vitamin D alone following hematopoietic cell transplantation (HCT).
- Trial name
- NCT02074631
- Testing
- Pamidronate, Calcium and vitamin D
- Where
- 2 sites in United States
- Volunteers
- 63 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Alveolar Ridge Deficiency, Alveolar Bone Loss
Titanium-Reinforced PTFE Membranes for Bone Augmentation
This prospective comparative clinical study evaluated vertical and horizontal bone gain after guided bone regeneration using titanium-reinforced dense PTFE (TiR-dPTFE) membranes versus reinforced PTFE mesh (RPM) in patients…
- Conditions
- Alveolar Ridge Deficiency, Alveolar Bone Loss, Jaw Atrophy
- Trial name
- NCT07520903
- Testing
- Titanium-reinforced dense PTFE membrane (TiR-dPTFE), Reinforced PTFE mesh (RPM)
- Where
- Portugal
- Volunteers
- 14 people
- Sponsor
- Universidade do Porto
Dental Restoration, Permanent, Dental Restorations
Clinical Investigation Measuring the Long Term Clinical Performance and Safety of Biodentine™ XP in Patients Treated for Coronal Restorative or Endodontic Dental Indications.
The aim of this present study is to collect additional data for the post-marketing follow-up of Biodentine™ XP and measure long-term (up to 10 years) performance and safety of the biomaterial in all its indications.
- Conditions
- Dental Restoration, Permanent, Dental Restorations, Endodontic Treatment
- Trial name
- BIOD XP (NCT06955429)
- Testing
- Dental restorative or endodontic treatment requiring Biodentine XP use
- Where
- 8 sites in Belgium, France
- Volunteers
- 275 people
- Sponsor
- Septodont
Maxillary Deficiency, Alveolar Bone Loss
Completely Versus Partially Guided Zygomatic Implant
The aim of study is evaluation of accuracy of completely versus partially limiting computer generated surgical three-dimensional guides during placement of zygoma implants in patients with atrophic maxillae.
- Trial name
- NCT06227351
- Testing
- completely limiting computer generated surgical three-dimensional guide, Partially limiting computer generated surgical three-dimensional guide
- Where
- Egypt
- Volunteers
- 6 people
- Sponsor
- Fayoum University
Periodontal Pocket, Periodontal Bone Loss
Using Xenograft Combined With Barrier Membrane to Improve the Formation of Deep Periodontal Pockets
To evaluate the clinical effect of site preservation after third molars extraction by using tooth extraction of third molars with site preservation using bio-oss and bio-guide in preventing the formation of deep periodontal…
- Conditions
- Periodontal Pocket, Periodontal Bone Loss, Impacted Third Molar Tooth
- Trial name
- NCT06318247
- Testing
- site preservation
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Dental Hospital of Zhejiang University School of Medicine
Chronic Periodontitis, Periodontal Bone Loss
Comparison of Clinical and Radiographic Parameters in the Application of Cross-linked Hyaluronic Acid 1.8% and Enamel Matrix Derivative in Periodontal Regeneration.
The aim of this study is to compare the effectiveness in periodontal regeneration of cross-linked hyaluronic acid at 1.8% (Hyadent BG®) with enamel matrix derivative (Emdogain®) in periodontal bone defects evaluating their…
- Trial name
- NCT04274244
- Testing
- Cross-Linked Hyaluronate Gel Prefilled Syringe 30 MG/3ML, Enamel Matrix Proteins (Active comparator group)
- Where
- Spain
- Volunteers
- 53 people
- Sponsor
- Andres Lopez Roldan
Alveolar Bone Resorption
Guided Bone Regeneration in Alveolar Socket
Following tooth extraction, volumetric changes in the soft and hard tissues of the extraction site are expected to occur with considerable resorption of the alveolar bone in both the vertical and the horizontal dimensions.
- Trial name
- GBR_socket (NCT05577663)
- Testing
- Routine treatment of the extraction socket, Socket seal technique by a free gingival graft, Socket seal technique using a synthetic resorbable membrane
- Where
- Greece
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki