Clinical trials: Resorption
Orthodontic Pathological Resorption of External Root
Efficacy of Injection Platelet-rich Fibrin(I-PRF) in Accelerate Alignment and Leveling
the aim of this study is to evaluate the effectiveness of injection I-PRF to accelerate alignment and leveling of the upper anterior teeth and reduce the time required for treatment.
- Trial name
- NCT04885842
- Testing
- injection I-PRF
- Where
- Syria
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Latakia University
Bone Loss, Alveolar, Resorption, Bone
The Effect of Growth Factor on Implant Osseointegration
In this study, concentrated growth factor obtained by centrifuging the patient's own blood and advanced platelet-rich fibrin liquids were applied to the implant cavity and surface.
- Conditions
- Bone Loss, Alveolar, Resorption, Bone, Osseointegration Failure of Dental Implant
- Trial name
- NCT04879446
- Testing
- Concentrated growth factor(CGF), Advanced platelet rich fibrin (A-PRF), Control side of concentrated growth factor study group
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Uğur Can ÜNLÜGENÇ
Edentulous Jaw, Bone Loss, Alveolar
Effects of Different Centrifuged Platelet Concentrates on Bone Remodelling Around Dental Implants
Platelet concentrates obtained from blood have been used as regenerative biomaterials in periodontal surgery. Along with the migration and proliferation of osteogenic cells, platelets accelerate bone regeneration by increasing…
- Conditions
- Edentulous Jaw, Bone Loss, Alveolar, Resorption, Bone
- Trial name
- NCT04851002
- Testing
- Application of concentrated growth factor with dental implants, Application of advanced platelet rich fibrin with dental implants, Control side of concentrated growth factor study group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Muhammet Atilgan
Alveolar Bone Resorption
Bone Formation Maxillary Sinus Width
According to previous scientific evidence lining on biological concept of bone regeneration into the maxillary sinus, an observational study was set up to record possible (hypothesized) difference in bone formation between…
- Trial name
- NCT04830670
- Testing
- sinus floor elevation with lateral approach
- Where
- 3 sites in Italy
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Class III Malocclusion, Root Resorption
Determining the Presence of RAP in Orthognathic Patients and Its Effect on Root Resorption by Biomarkers
A prospective clinical trial to what extent inflammatory biomarkers are affected by the medication after orthognathic surgery in early surgical cases and whether these biomarkers affects the amount of maxillary or mandibular…
- Trial name
- RAP (NCT04823325)
- Testing
- Orthognathic Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Immediate Implant Placement, Bone Regeneration
Simvastatin Around Immediate Implant
The study evaluated the effect of local application of simvastatin around immediate implant on the amount of gap fill, ridge dimensional alterations and bone density in humans.
- Conditions
- Immediate Implant Placement, Bone Regeneration, Alveolar Bone Resorption
- Trial name
- NCT04803500
- Testing
- Simvastatin
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Teeth Mesial Drift, Bone Injury
Biological Anchorage With Selective Micro-osteoperforations (MOPs) in Canine Distalization
To evaluate the effect of selective micro-osteoperforations (MOPs) on the amount of distal movement of the upper canine, the mesio-distal inclination of the canine and the messiah movement of the upper first molar.
- Conditions
- Teeth Mesial Drift, Bone Injury, Orthodontic Pathological Resorption of External Root
- Trial name
- NCT03741504
- Testing
- micro-osteoperforations (MOPs)
- Where
- 2 sites in Colombia
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Fundación Universitaria CIEO
Bone Loss, Alveolar Bone Resorption
Biomaterial Clinical Performance in a Socket Preservation Model
When a dental extraction is performed, sequential cascade of events happens that lead to a modeling and remodeling of the area. This phenomenon leads to bone resorption and consequential volume loss atrophy.
- Trial name
- NCT04789759
- Testing
- Socket Preservation - Bond Apatite synthetic bone substitute, Socket healing - No Filler
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- International Advanced Dentistry, Lisbon
Bone Resorption
Guided Bone Regeneration Using Bovine-derived Xenograft in Combination With or Without Injectable Platelet-rich Fibrin
The aim of the study was to compare the change in augmentation thickness after guided bone regeneration (GBR) using bovine-derived xenograft in combination with or without injectable platelet-rich fibrin (i-PRF).
- Trial name
- NCT04709523
- Testing
- bovine-derived xenograft with i-PRF, bovine-derived xenograft alone
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ege University
Alveolar Bone Resorption
Alveolar Ridge Preservation Following Tooth Extraction Using Advanced Platelet Rich Fibrin (A-PRF) Versus Platelet Rich Fibrin (PRF)
the aim of this study is clinically and radiographically evaluate the use of advance platelet rich fibrin (A-PRF) versus platelet rich fibrin (PRF) in preservation of alveolar ridge following tooth extraction
- Trial name
- NCT04434703
- Testing
- Platelet rich fibrin (PRF), Advanced platelet rich fibrin (A-PRF), blood clot
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Endodontic Disease, Tooth Resorption
Volumetric Analysis of Resorption Types on CBCT
More accurate management of resorption can be achieved thanks to the three-dimensions volumetric and linear analysis, and the axial classification presented in this study.
- Trial name
- NCT04617301
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Type 2 Diabetes Mellitus
Effects of Gut Peptides on Bone Remodeling. KS-4-Diabetes-19
Both GLP-2 and GIP reduce the bone resorption (measured as CTX) in healthy persons. In this study, we will investigate wether GLP-2 and GIP is reducing CTX in persons with type 2 diabetes.
- Trial name
- NCT03867656
- Testing
- GLP-2, GIP
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Bone Resorption
Bone Changes Assessment in Screw-Retained Maxillary Complete Denture With Electric Welded Framework Versus Cast One
comparing bony changes around implants that will be joined by ametal framework either with electric weiling or with the conventional casting metal
- Trial name
- NCT04548258
- Testing
- electric intraoral weilding, casting
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
Orthodontic Treatment
Curve of Spee: Speed of Leveling Using Different Orthodontic Archwires
The objectives if this study was to evaluate the efficacy of 3 different rectangular archwires in the correction of the curve of Spee (COS), to record the time needed to level excessive COS in the mandibular arch using the 3…
- Trial name
- NCT04549948
- Testing
- 0.017X0.025 Stainless steel, 0.019X0.025 Stainless steel, 0.021X0.025 B-Titanium archwire
- Where
- Jordan
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Bone Resorption
Guided Bone Regeneration With Customized Titanium Meshes
The aims of this prospective clinical study are to evaluate: a) the effectiveness of digitally customized titanium meshes in association with autologous bone particles and bovine bone mineral and covered with collagen membranes…
- Trial name
- NCT04480073
- Testing
- Customized CAD-CAM Titanium Mesh (Y-xoss CBR® by Reoss -Filderstadt - Germany) for Guided Bone Regeneration of atrophic alveolar ridges
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Milan
Alveolar Bone Resorption
Radiographic and Histological Evaluation of Regenerated Bone After Grafting Using Allograft Shell and Autogenous Chips
The clinical cases in the present study described the khoury shell technique using an allograft plate and autogenous chips, for horizontal reconstruction of the anterior alveolar ridge in the esthetic zone.
- Trial name
- Shell grafting (NCT04324697)
- Testing
- Horizontal alveolar bone augmentation
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- October 6 University
Bone Resorption, Osteoporosis
The Effect of Protein Supplementation on Bone Health in Healthy Older Men and Women
Women and men consuming a low protein diet may be at risk for bone loss. The purpose of this study is to determine whether a daily protein supplement will improve bone health among healthy older adults.
- Trial name
- NCT00421408
- Testing
- Whey protein supplement
- Where
- 2 sites in United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Yale University
Loss of Teeth Due to Extraction, Bone Resorption
Effect of Shock-wave Therapy on the Resorption and Bone Formation in Maxillary Postextraction Sockets
The extracorporeal shock wave therapy (ESWT) has shown good results in bones and soft tissues of the lower and upper extremities such as: pseudoarthrosis, promoting bone formation of delayed or nonunion fractures, tendinopathies…
- Trial name
- Shockwave (NCT04331028)
- Testing
- Shockwave therapy
- Where
- Spain
- Sponsor
- Rui Figueiredo
Alveolar Ridge Resorption After Extraction
Alveolar Ridge Preservation With Polycaprolactone Scaffold for Implant Site Development
It has been shown through research that alveolar ridges (Part of jaw bone holding teeth) tend to lose width and height after extraction of teeth.
- Trial name
- NCT00466414
- Testing
- Polycaprolactone Scaffold
- Where
- Singapore
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Alveolar Bone Loss, Bone Resorption
Outcome of Implant-supported Overdentures
The aim of this pilot study was to assess survival rates and peri-implant bone loss of two narrow-diameter titanium-zirconium implants supporting maxillary and mandibular overdentures during an observation time of 3 years.
- Conditions
- Alveolar Bone Loss, Bone Resorption, Dental Implants, Edentulous Maxilla
- Trial name
- NCT03777748
- Testing
- dental implants and stud attachments
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University