Clinical trials: Respiration Rate Detection
Nonsmall Cell Lung Cancer
Comparison of qPCR to IHC and FISH for Detection of ALK Fusion Mutations in FFPE Tissue From NSCLC Patients
The anaplastic lymphoma kinase gene(ALK) is mutated approximately 5% of non-small cell lung cancers. Testing for this gene is important because there are drugs known as ALK inhibitors that have been shown to significantly delay…
- Trial name
- PCRTALK (NCT02010047)
- Testing
- ALK qPCR assay
- Where
- 7 sites in Canada
- Volunteers
- 166 people
- Sponsor
- British Columbia Cancer Agency
Idiopathic Pulmonary Fibrosis
Detection of Early Idiopathic Pulmonary Fibrosis
The purpose of the study is to determine if miR200 family may serve as a biomarker of IPF.
- Trial name
- NCT03457935
- Testing
- blood samples
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Temple University
Chronic Obstructive Pulmonary Disease
Evaluation of the Use of a Remote Monitoring and Follow-up Option for Patients With Chronic Obstructive Pulmonary Disease (BOREAL)
The purpose of this study is to evaluate the ability of the Bora Care remote monitoring solution to detect early acute exacerbations of Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- BOREAL (NCT05759247)
- Testing
- BORA Band (wristband)
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Carcinoma, Non-small-cell Lung Cancer
Circulating Tumor DNA Detection in Surveillance of Surgical Lung Cancer Patients
Conduct a prospective study to confirm blood and urine ctDNA detection value in non-small-cell lung cancer patients.
- Conditions
- Carcinoma, Non-small-cell Lung Cancer, Lung Neoplasms
- Trial name
- NCT02696525
- Where
- 3 sites in China
- Volunteers
- 145 people
- Sponsor
- Peking University People's Hospital
Lung Cancer (Suspected or Confirmed), Cryoablation
One-stop Diagnosis and Treatment for Suspected Lung Cancer: Combined RBS, nClE, OBCT and Ablation
Using RBS as the navigation and treatment platform, precisely navigate to the target lesion. Utilize r-EUBS and nCLE to identify the lesion, and when the confocal AI model recognizes the lesion as malignant, perform a biopsy.
- Conditions
- Lung Cancer (Suspected or Confirmed), Cryoablation, Robotic Bronchoscopy System, Confocal Laser Endomicroscopy
- Trial name
- One-stop (NCT07521618)
- Testing
- Ablation
- Volunteers
- 30 people
- Sponsor
- Guangzhou Medical University
Pregnancy, Sleep Apnea Syndrome
Detection of Sleep Apnea Syndrome (OSA) in Pregnant Women and Assessment of Impact of OSA on Pregnancy Course
To assess prevalence of obstructive sleep apnea during pregnancy and its impact on prgnancy course and materno foetal wellbeing.
- Conditions
- Pregnancy, Sleep Apnea Syndrome, Obstructive Sleep Apnea
- Trial name
- NCT02649933
- Testing
- Watch PAT 200
- Where
- Belgium
- Volunteers
- 8 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
BPD - Bronchopulmonary Dysplasia, Pulmonary Hypertension
Controlled Remote Monitoring and Optimization of Oxygen Therapy in Preterm Infants
The project is a national, prospective, multicenter, interventional pilot project focused on controlled remote monitoring and optimization of oxygen therapy for premature infants in the Czech Republic.
- Trial name
- NCT07161908
- Testing
- Pulse oximeter
- Where
- 4 sites in Czechia
- Volunteers
- 70 people
- Sponsor
- Institute of Health Information and Statistics of the Czech Republic
Neoplasms, Solid Tumor
Methylation Profile Test (Methylscape) in Body Fluids for Multi-Cancer Detection and Monitoring in Colombia
DNA methylation changes occur early and broadly during carcinogenesis. Methylscape is a rapid assay that detects global DNA methylation patterns in body fluids (blood, urine, and saliva) and may detect a cancer signal and predict…
- Conditions
- Neoplasms, Solid Tumor, Breast Neoplasms, Lung Neoplasms
- Trial name
- METHYLSCAPE-CO (NCT07741435)
- Testing
- Methylscape DNA methylation assay
- Where
- Colombia
- Volunteers
- 3,250 people, healthy volunteers welcome
- Sponsor
- Centro de Tratamiento e Investigación sobre Cáncer, Luis Carlos Sarmiento Angulo
Acute Respiratory Distress Syndrome
Discovery of New Early Detection Biomarkers From Peripheral Blood of Acute Respiratory Distress Syndrome(ARDS)
Acute respiratory distress syndrome (ARDS) has a very poor prognosis and high mortality. To improve the early diagnosis of ARDS, there is an urgent need for novel biomarkers of ARDS.
- Trial name
- NCT02967471
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated Hospital of Southern Medical University
Covid19
Detection of Covid-19 by Volatile Organic Compounds in Exhaled Breath
Our primary aim is to collect breath samples from COVID-19 positive patients at the time of diagnosis, during and after recovery using the same patient as his/her own control to identify VOCs specific to SARS-COV-2 viral…
- Trial name
- Covid-VOC (NCT04714333)
- Where
- 2 sites in Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- British Columbia Cancer Agency
Extracellular Fluid Alteration, Corona Virus Infection
Extracellular Water in Covid 19 Pneumonia
According to various studies Covid 19 pneumonia has a very similar clinical course to Acute Respiratory Distress Syndrome (ARDS) which has clarified by Berlin definition.
- Trial name
- NCT04416009
- Testing
- NİCaS
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Aspergillosis, Invasive Pulmonary
PCR Based Detection of Azole Resistance in A. Fumigatus to Improve Patient Outcome.
A standard treatment protocol for invasive aspergillosis (IA) will be implemented in several academic hematology centers in the Netherlands in which a diagnostic test demonstrating azole resistance by multiplex real-time…
- Trial name
- AzorMan (NCT03121235)
- Testing
- PCR based detection of azole resistance in A. fumigatus
- Where
- 8 sites in Netherlands
- Volunteers
- 320 people
- Sponsor
- Erasmus Medical Center
Viral Respiratory Infection
Sample Collection to Evaluate an Investigational Instrument for the Detection of Respiratory Viruses in Nasopharyngeal Swabs
The purpose of this sample collection study is to prospectively collect respiratory viral clinical samples, conduct standard of care comparator testing and archive the collected residual samples for future testing in order to…
- Trial name
- NCT01806285
- Volunteers
- 205 people
- Sponsor
- GenMark Diagnostics
Chest Pain, Stroke Acute
Evaluation and Optimization of Telephone Triage Using Artificial Intelligence (AI) Models for the Detection of Demands for Time-dependent Pathology at the Emergency and Urgent Care Coordination Center (CCUE).
Improving Telephone Triage in Emergency Calls with AI The Coordinating Centre for Urgencies and Emergencies in Andalusia (CCUE) handles thousands of calls every day.
- Conditions
- Chest Pain, Stroke Acute, Respiratory Failure, Cardiac Arrest (CA)
- Trial name
- TrIAje Project (NCT07247669)
- Where
- Spain
- Volunteers
- 5,000,000 people
- Sponsor
- Centro de Emergencias Sanitarias 061 Andalucía
Breast Cancer, Colorectal Cancer
Detection of Cancer in Breath Samples by Trained Detection Dogs
The goal of this study is to show that trained detection dogs can identify breast, lung, prostate or colorectal cancer by sniffing masks containing breath samples.
- Conditions
- Breast Cancer, Colorectal Cancer, PROSTATE CANCER, Lung Cancer
- Trial name
- NCT06255041
- Where
- 2 sites in Israel
- Volunteers
- 1,386 people, healthy volunteers welcome
- Sponsor
- SpotitEarly
Lung Cancer
Exhaled Breath Biomarkers in Lung Cancer
Analysis of volatile organic compounds (VOCs) is a new attractive non-invasive field in medical diagnostics. These VOCs can be detected via the exhaled breath.
- Trial name
- NCT01386203
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Sheba Medical Center
Aortic Aneurysm, Thoracic
Detection of Hypoxia in Human Thoracic Aorta Using Pimonidazole Hydrochloride
This is a prospective study designed to determine the safety and value of Hypoxyprobe-1 (pimonidazole hydrochloride (-HCl)) to detect levels of tissue hypoxia in patients presenting with ascending aortic aneurysm.
- Trial name
- NCT03410420
- Testing
- Pimonidazole hydrochloride
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Thomas Gleason
Respiratory Rate
Mixed Methods Evaluation of a Novel Apnoea Event Detection Monitor
This investigation is looking at a currently available technology to see if it could have another use i.e. in helping to diagnose patients with sleep apnoea.
- Trial name
- NCT03149744
- Testing
- RespiraSense Sleep Screener
- Where
- United Kingdom
- Volunteers
- 127 people
- Sponsor
- PMD Solutions
Lung Neoplasms, Stomach Neoplasms
Default Option Nudging Intervention to Improve the Adherence Rates of Cancer Screening
The goal of this clinical trial is to learn if a behavioral "nudge" strategy, specifically a default option, can improve screening participation in populations at high risk for lung and stomach cancer.
- Conditions
- Lung Neoplasms, Stomach Neoplasms, Early Detection of Cancer, Patient Compliance
- Trial name
- NCT07682220
- Testing
- Default Options
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Harbin Medical University
SARS-CoV2 Infection
TekiTrust Tests to Determine the Level of SARS-COV-2/COVID-19 Neutralizing Antibodies in the Blood
The purpose of this study is to determine if the TekiTrust Enzyme-Linked Immunosorbent Assay (ELISA) Kit and TekiTrust Rapid Test can accurately determine the amount of antibodies to fight the COVID-19 virus in sampled blood…
- Trial name
- NCT05338762
- Where
- 5 sites in United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- MiCo BioMed Co., Ltd.