Clinical trials: Respiratory Diaphragm
DIAPHRAGM -Ultrasound -Weaning -Mechanical Ventilation
Diaphragm Training Ultrasound
Common neurological indications of intubation and initiation of mechanical ventilation (MV) include ischemic and hemorrhagic stroke, neurotrauma, and intracranial hemorrhage.
- Trial name
- DiaphUS (NCT04186325)
- Testing
- DIAPHRAGMATIC exercising
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Mechanical Ventilation Complication, Pediatric ALL
Measuring Thickness of the Normal Diaphragm in Children Via Ultrasound.
Critically ill children treated with invasive mechanical ventilation (iMV) in a paediatric intensive care unit (PICU) may suffer from complications leading to prolonged duration of ventilation and PICU stay.
- Conditions
- Mechanical Ventilation Complication, Pediatric ALL, Intensive Care Unit Acquired Weakness
- Trial name
- NCT04589910
- Testing
- diaphragm thickness and thickening fraction
- Where
- Netherlands
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
High-flow Nasal Cannula, Ultrasound Evaluation
Ultrasound Evaluations of Diaphragm and Intercostal Muscle to Predict the Failure of High-Flow Nasal Cannula Therapy
The study aims to predict the failure of High-flow Nasal Cannula oxygenation therapy by ultrasound evaluation of diaphragm and intercostal muscle contraction during the first 24 hours.
- Conditions
- High-flow Nasal Cannula, Ultrasound Evaluation, Diaphragm and Intercostal Muscle
- Trial name
- NCT06375538
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai Zhongshan Hospital
Gastroesophageal Reflux Disease
Diaphragmatic Myofascial Release in Gastroesophageal Reflux Disease
This study is a double blinded randomized clinical trial with two arms which aims to study the effects of diaphragmatic myofascial release in patients with gastroesophageal reflux disease (GERD).
- Trial name
- GERD (NCT03299985)
- Testing
- Diaphragmatic myofascial release
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Cardenal Herrera University
Diaphragmatic Plication, Unilateral Diaphragmatic Paralysis
Clinical and Sonographic Diaphragm Evaluation Post-plication
Objectives: We aim to clarify the role of diaphragm ultrasonography (DUS) in evaluating the outcome of surgical diaphragmatic plication (SDP) in adults with symptomatic unilateral diaphragmatic paralysis (UDP).
- Conditions
- Diaphragmatic Plication, Unilateral Diaphragmatic Paralysis, Diaphragm Ultrasonography
- Trial name
- NCT04052295
- Testing
- surgical diaphragmatic plication
- Volunteers
- 40 people
- Sponsor
- South Valley University
Lung Neoplasm, Lung Cancer
Lung Ultrasound to Assess Aeration Loss After Lung Resection Surgery
The purpose of this prospective observational study is to assess perioperative changes in lung aeration after lung resection surgery using lung ultrasound, and to explore their relationship with oxygenation, inflammatory…
- Conditions
- Lung Neoplasm, Lung Cancer, Lung Resection Surgery, Thoracic Surgery
- Trial name
- THORUS (NCT04677309)
- Testing
- Perioperative lung ultrasound assessment
- Where
- Spain
- Volunteers
- 32 people
- Sponsor
- Ana Broseta Lleó
Weaning Failure of Mechanical Ventilation, Diaphragm Ultrasonography
Use of Diaphragm Ultrasound and Evaluation of Respiratory Parameters in Determining Weaning Success in Geriatric Patients
This study aims to evaluate the effectiveness of ultrasound-based diaphragmatic measurements in predicting weaning success in patients aged 65 and older who are receiving mechanical ventilation.
- Conditions
- Weaning Failure of Mechanical Ventilation, Diaphragm Ultrasonography, Geriatric
- Trial name
- NCT07044063
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Stroke, Inspiratory Muscle Training
Inspiratory and Trunk Muscle Activity During IMT on Stable and Unstable Surfaces in Stroke Patients
This study aims to investigate the differences in muscle recruitment of the diaphragm (assessed using ultrasound), the sternocleidomastoid (SCM) and trunk muscles (both measured via surface electromyography (sEMG)), during loaded…
- Conditions
- Stroke, Inspiratory Muscle Training, Diaphragm, Sternocleidomastoid Muscles
- Trial name
- NCT06877338
- Testing
- Loaded breathing on stable and unstable surfaces
- Volunteers
- 24 people
- Sponsor
- Hong Kong Metropolitan University
Diaphragm Paralysis
The Effect of Interscalene Peripheral Nerve Block With 0.25% Bupivacaine vs 0.125% Bupivacaine on Lung Function
Peripheral nerve blocks are used to provide post-operative pain relief. Nerve blocks in the neck, in the interscalene area, provide pain relief after shoulder surgery but can cause temporary weakness or paralysis of the…
- Trial name
- NCT01429584
- Testing
- interscalene nerve block with 0.25% bupivacaine, interscalene block with 0.125% bupivacaine
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Utah
Amyotrophic Lateral Sclerosis
Inspiratory Muscle Training With Powerbreath Device in Patients With ALS
Abstract: Context/background: people affected by Amyotrophic Lateral Sclerosis (ALS) see their own life totally disturbed after the diagnosis.
- Trial name
- NCT04889248
- Testing
- Inspiratory Muscle Training with Powerbreath IMT device.
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidad Francisco de Vitoria
Regional Anesthesia, Diaphragm Issues
Ultrasound Assessment of Diaphragmatic Dysfunction in Regional Anesthesia
Awake thoracic surgery is a feasible and safe alternative to general anesthesia for pulmonary biopsy in interstitial lung disease patients, but there is still no evidence as to its superiority in terms of outcome.
- Conditions
- Regional Anesthesia, Diaphragm Issues, Thoracic Surgery, Ultrasounds
- Trial name
- NCT04700943
- Testing
- Regional awake anesthesia
- Where
- Italy
- Volunteers
- 41 people
- Sponsor
- University of Turin, Italy
Kidney Disease
Inspiratory Muscle Training in Patients With End-stage Renal Disease
Background: Patients with chronic kidney disease on hemodialysis may have reduced diffusion capacity, lung function and gas exchange due to mechanical and hemodynamic changes in the respiratory system, and decreased respiratory…
- Trial name
- NCT02599987
- Testing
- POWERbreathe® Classic Light
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Universidade Federal de Pernambuco
Respiratory Paralysis
Diaphragmatic Height Index: the New Diagnostic Test for Phrenic Nerve Dysfunction
Diaphragmatic contraction is controlled by phrenic nerve which consists of anterior rami of 3rd- 5th cervical nerve roots. Usually, It can't be evaluated from history taking and physical examination.
- Trial name
- NCT01450917
- Volunteers
- 245 people
- Sponsor
- Mahidol University
Inspiratory Muscle Strength
Inspiratory Muscle Warm-up Protocol
The capacity of athletes to demonstrate their abilities to the fullest extent is contingent upon their physical fitness. Oxygen delivery and utilization become crucial during athletic pursuits, as muscle oxygen demand increases…
- Trial name
- NCT06894316
- Testing
- Inspiratory muscle warm-up training, General Warm-up Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Burak Karaca
Systemic Sclerosis
Sleep Quality, Stress, Depression, Blood Pressure Responses to Diaphragmatic Respiratory Exercise in Systemic Sclerosis
systemic sclerosis women usually report problems such as stress/depression, fatigue, not deep sleep. complementary therapies may improve the reported problems in those patients
- Trial name
- NCT05623917
- Testing
- Tele-supervised diaphragmatic respiratory exercise
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Respiratory Insufficiency Requiring Mechanical Ventilation
Effects of Neuromuscular Electrical Stimulation on Critically Ill Patients With Mechanical Ventilation
Up to 25% of patients who require mechanical ventilation (MV) more than seven days in the intensive care unit (ICU) develop muscle weakness, which comprises deep muscle weakness , including the respiratory muscles.Early active…
- Trial name
- NCT05217511
- Testing
- Neuromuscular Electrical Stimulation
- Where
- China
- Volunteers
- 47 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Weaning Failure
Improving Our Understanding of Respiratory Muscle Training to Facilitate Weaning From Mechanical Ventilation in the ICU
Mechanical ventilation is a life-saving treatment frequently applied in intensive care unit (ICU). Nonetheless, by putting at rest the respiratory muscles, it can lead to respiratory muscle weakness and atrophy, which are…
- Trial name
- TrainToWean (NCT04658498)
- Testing
- Procedure: Usual Care (UC), Procedure: UC + HI-IMT
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- KU Leuven
Weaning Failure, Central Respiratory Depression
Exploration of Mechanisms for Weaning Failure
This study is a prospective physiologic study. The primary study population will be adult invasive tracheal intubated patients with COPD, and investigators will collect relevant demographic data, vital signs, and baseline…
- Conditions
- Weaning Failure, Central Respiratory Depression, Diaphragm Injury, Phrenic Nerve Disorder
- Trial name
- NCT06424314
- Testing
- Monitoring of respiratory mechanics parameters
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Hernias, Diaphragmatic, Congenital
Resistance Exercise in Children With Post-operative Congenital Diaphragmatic Hernia
Congenital diaphragmatic hernia (CDH) is a life-threatening condition with long-term complications including respiratory tract infections, respiratory muscle weakness, and abnormal lung functions.
- Trial name
- hernia (NCT04900649)
- Testing
- chest resistance exercise, chest expansion exercises
- Where
- Saudi Arabia
- Volunteers
- 32 people
- Sponsor
- Qassim University
Ventilator Weaning, Ultrasound
Weaning Ventilator Using Heart, Lung And Diaphragm Ultrasound
Postextubation distress is detrimental to the prognosis of critically ill patients with successful spontaneous breathing trial. Failure to wean is known to be connected with heart, lung, and diaphragm problems.
- Trial name
- NCT06321848
- Where
- Vietnam
- Volunteers
- 199 people
- Sponsor
- Hanoi Medical University