Clinical trials: Respiratory Function Impaired
Airway Obstruction
Ultrasonography Versus Palpation for Identification of the Cricothyroid Membrane
After a structured teaching program anaesthetists are educated in identifying the cricothyroid membrane with ultrasonography. Thereafter their ability to do so is compared with their ability to do so with palpation.
- Trial name
- NCT02975791
- Testing
- Marking the cricothyroid membrane after ultrasound, Marking of the cricothyroid membrane after Palpation
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Nasal Obstruction
Design and Application of Vitamin D Films for Burn Healing After Cauterizing Surgery
One of this method's drawbacks is the healing of cauterized cartilage after processing. It was reported that the healing is so slow as no dosage form can reach this place in addition to the scares produced from healing is very…
- Trial name
- NCT05142072
- Testing
- Vitamin D3
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Deraya University
Oxygen Deficiency, Desaturation of Blood
THRIVE Use in Pediatric Populations- Multi Site
THRIVE (Transnasal Humidified Rapid-Insufflation Ventilatory Exchange) refers to the use of high-flow nasal cannula to augment the ability to oxygenate and ventilate a patient under general anesthesia.
- Conditions
- Oxygen Deficiency, Desaturation of Blood, Hypoventilation, Anesthesia; Adverse Effect
- Trial name
- NCT04322994
- Testing
- Transnasal Humidified Rapid-Insufflation Ventilatory Echange
- Where
- 5 sites in United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Stanford University
Diaphragm Paralysis Due to Local Anesthesia, Anterior Suprascapular Nerve Block
Anterior Suprascapular Nerve Block is an Effective and Diaphragm Protective Approach for Arthroscopic Shoulder Surgery
Interscalene block is still the gold standard in shoulder surgery analgesia. The most important side effect is diaphragm paralysis due to the phrenic nerve being affected.
- Conditions
- Diaphragm Paralysis Due to Local Anesthesia, Anterior Suprascapular Nerve Block, Analgesia, Arthroscopic Shoulder Surgery
- Trial name
- NCT04626869
- Testing
- Evaluation of Diaphragm Movement
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alper Tunga Dogan
Asthma in Children, Lung Function Decreased
Lung Function Variability in Children and Adolescents
Long-term variability analysis of peak expiratory flow (PEF) and forced expiratory volume in 1 s (FEV1) has been successfully used in research to predict the exacerbation of the disease in adult individuals with asthma.
- Trial name
- LUV (NCT04163146)
- Testing
- Measurements of PEF and FEV1
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Patras
Respiratory Insufficiency
"Inspiratory Muscle Training in Older Women"
Objective: To evaluate the effectiveness of two protocols of inspiratory muscle training (IMT) in older women to improve respiratory strength, spirometric parameters and dyspnea.
- Trial name
- NCT03827356
- Testing
- Inspiratory muscle trainer (IMT)
- Where
- Spain
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
COPD
Effects of Combined Cognitive Rehabilitation in COPD Patients
This study was to examine the effect of endurance training combined with cognitive training in patients with COPD. The intervention group underwent Cognitive Training added to Endurance Training and the control group underwent…
- Trial name
- NCT03907839
- Testing
- clinical trials
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Faculty of Medicine, Sousse
Nonallergic Irritant Rhinitis
Intranasal Capsaicin Treatment for Non-Allergic Irritant Rhinitis
The proposed study seeks to investigate the effect of intranasal capsaicin treatment in patient with Non-allergic irritant rhinitis (NAIR), as well as evaluate optical rhinometry (ORM) as a means to quantify symptomatic…
- Trial name
- NCT02493257
- Testing
- Capsaicin
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Respiratory Depression
Precision Medicine in Anesthesia: Genetic Component in Opioid-induced Respiratory Depression
The concept of precision medicine - taking individual variability into account when planning preventions and interventions - is not new but is quickly gaining attention in this age of powerful methodology of patient…
- Trial name
- NCT03441282
- Testing
- Fentanyl
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Respiratory Failure, Intubation
Efficiency of the King Vision Video Laryngoscope
The investigators studied the efficiency of Macintosh laryngoscope and the King Vision video laryngoscope in adult patients scheduled for general anesthesia.
- Trial name
- NCT02482870
- Testing
- Macintosh laryngoscope, King Vision video laryngoscope
- Where
- Turkey (Türkiye)
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Airway Obstruction
Video Game Training on Intervention in Adult Airway Obstruction
Foreign body aspiration occurs as a result of partial or complete airway obstruction. In the case of complete obstruction, mechanical asphyxia can lead to insufficient ventilation and oxygenation, leading to death.
- Trial name
- NCT06843694
- Testing
- video game
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Alpha 1-antitrypsin Deficiency (AATD)
Screening for Alpha-1 Antitrypsin Deficiency in Patients With Airway Obstruction
Brief Summary: This study aims to find out if a genetic condition called Alpha-1 Antitrypsin Deficiency (AATD) is more common in people who have shortness of breath and signs of airway obstruction on their breathing tests.
- Trial name
- AATD-SAO (NCT07152834)
- Testing
- Blood Sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 734 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
COVID-19, Sleep Disorder
Investigation of Respiratory Muscle Strength, Exercise Capacity, Physical Activity and Sleep Quality Level in Individuals With Covid-19 Infection
COVID-19 infection was identified in Wuhan, China at the end of 2019 and turned into a pandemic in a short time. In our country, the pandemic continues at full speed and patients are being treated in various clinical pictures.
- Conditions
- COVID-19, Sleep Disorder, Respiratory Failure
- Trial name
- NCT06008470
- Testing
- observational tests
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Diaphragmatic Paralysis, Healthy Volunteers
Assesment of New Devices for the Diagnostic Evaluation of Diaphragmatic Dysfunction
this study aim to evaluate wether new, non-invasive and non-contact devices such as Structured Light Plethysmography (SLP) and Sonar would be able to accurately detect and quantify diaphragm dysfunction (mono-or-bilateral) by…
- Trial name
- DYSDIA (NCT03463798)
- Testing
- Sonar, Structured light plethysmography (SLP)
- Where
- France
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
Cognitive Impairment, Bipolar Disorder
Effects of Altitude-like Cognition Training on Neuroplasticity and Cognitive Functions
The goal of this clinical trial is to investigate the effects of a three-week altitude-like cognition training intervention in healthy individuals (substudy 1) and symptomatically stable patients with mood disorders (depression…
- Conditions
- Cognitive Impairment, Bipolar Disorder, Depression
- Trial name
- ALTIBRAIN (NCT06121206)
- Testing
- Altitude-like hypoxia (12% O2), Normoxia (20% O2), Cognitive training
- Where
- Denmark
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
Airway Obstruction
Airflow Perturbation Device (APD) for the Evaluation of Pulmonary and Sleep Disorders
In a prospective, observational study the investigators compared resistance values measured using the airway perturbation device (APD) to impulse oscillometry and spirometry.
- Trial name
- NCT03054116
- Testing
- Airflow pertubation device
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Respiratory Failure
Validation of a Dynamic Evaluation Tool in Respiratory Failure
Determing optimal time of ventilator disconnection is a challenge for both acute and chronic neuromuscular disease. In one case it is helpful for weanning from ventilator and in the other to optimize daytime ventilation in the…
- Trial name
- TELERESP (NCT01807663)
- Testing
- healthy volonteers, Free breath monitoring
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Bronchial Asthma, Bronchiectasis
The Use of Entropy to Assess Sleep Disordered Breathing in Chronic Respiratory Disease
Research is being conducted into chronic respiratory diseases, including chronic obstructive pulmonary disease (COPD), asthma, interstitial lung disease, and bronchiectasis.
- Conditions
- Bronchial Asthma, Bronchiectasis, ILD, COPD
- Trial name
- NCT07060079
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University College, London
Nasal Obstruction, Deviated Nasal Septum
Diagnosis of Respiratory Disorders by the Numerical Modeling.
Chronic Nasal obstruction (CNO) is not currently measurable objectively because clinicians use validated declarative self-questionnaires whose results are linked to the level of understanding, the acute or chronic clinical…
- Trial name
- JUNE (NCT06670261)
- Testing
- Data collection
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Respiratory Insufficiency, Ventilation Therapy; Complications
KAP Asynchrony Survey
The investigators developed a web-based survey to assess knowledge, attitudes and practice of health care professionals about patient-ventilator asynchrony.
- Conditions
- Respiratory Insufficiency, Ventilation Therapy; Complications, Ventilators, Mechanical, Respiration, Artificial
- Trial name
- KAPA (NCT03439683)
- Testing
- Survey about patient-ventilator asynchrony
- Where
- Brazil
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital