Clinical trials: Respiratory Sounds
COVID-19
Collecting Respiratory Sound Samples From Corona Patients to Extend the Diagnostic Capability of VOQX Electronic Stethoscope to Diagnose COVID-19 Patients
Technological developments in the recent decades has enabled the integration of electronic and digital components in the stethoscope design, in an attempt to improve auditory performance and, moreover, to assist in improving…
- Trial name
- NCT04910191
- Testing
- Electronic stethoscope
- Where
- 3 sites in Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sanolla
Healthy
Vibration Response Imaging in Healthy Subjects
The primary purpose is to test intersubject variability and establish the qualitative features of normal VRI images and the range of normality of the VRI quantitative lung data values that may be used to differentiate normal from…
- Trial name
- NCT00495430
- Where
- Israel
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- Deep Breeze
Sleep-disordered Breathing, Snoring
Hemodynamics Response to Upper Airway Obstruction in Marfan Syndrome
Upper airway obstruction (UAO) is an unrecognized source of hemodynamic stress that may contribute to aortic adverse events in persons with Marfan Syndrome (MFS).
- Trial name
- MSB (NCT03985657)
- Testing
- CPAP
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Wheezing, Upper Respiratory Tract Infections
Nasal Resveratrol and Wheezing Episodes in Preschool Children
As most of the upper airways infections (UAI) leading to wheezing are secondary to viral triggers, the possible antinflammatory and antiviral role of resveratrol has been suggested in several studies, both in vitro and in vivo.
- Trial name
- RSVchild (NCT04689412)
- Testing
- Resveratrol
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Of Perugia
Snoring, Sleep Disturbances
Evaluating Sleep Quality With Emerging Technologies
To investigate the sleep quality of the adult orthodontic patient population at the Case Western Reserve University School of Dental Medicine using the NOSE Questionnaire, STOP-BANG Questionnaire, SleepCycle app, and Belun Ring.
- Conditions
- Snoring, Sleep Disturbances, Hypoxia, Obstructive Sleep Apnea (OSA)
- Trial name
- NCT06900530
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Coughing, Post Operative Complications
Comparison of Postoperative Pulmonary Complications Between Smokers and Nonsmokers
This is a prospective observational study designed to evaluate the effect of smoking on early postoperative respiratory symptoms such as cough, airway secretions, and wheezing in adult patients undergoing elective abdominal…
- Conditions
- Coughing, Post Operative Complications, Wheezing, Smoking, Tobacco
- Trial name
- MINOPPC (NCT06982911)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- mehmet özkılıç
Sleep Apnea
Validation of Sleep Apnea Diagnosis Device
Obstructive sleep apnea (OSA) is common and largely underdiagnosed disease. The standard method for the diagnosis of OSA is a complete night polysomnography (PSG). Simple methods for OSA diagnosis are necessary.
- Trial name
- NCT03526133
- Testing
- Polysomnography (PSG) and wireless sensor Oxistar
- Where
- Brazil
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Snoring, Obstructive Sleep Apnea
Safety, and Tolerability of the ZENS Device (PLUTO)
The primary objective of the PLUTO study is to evaluate the safety and tolerability of the ZENS transcutaneous nerve stimulator device in primary snorers and those with mild obstructive sleep apnea.
- Trial name
- NCT04063917
- Testing
- ZENS
- Where
- 2 sites in Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Zennea Technologies Inc.
Sleep Apnea Syndromes, Snoring
Tracking Breathing During Sleep With Non-contact Sensors
The purpose of this study is to evaluate the feasibility of tracking breathing during sleep with non-contact sensors (for example, microphones or wireless movement sensors).
- Trial name
- NCT01680380
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Asthma, Respiratory Tract Infections
Fish Oil in pREgnancY for Personalized Prevention of Early Childhood Asthma
The overall aim of the study is to develop a nutritional preventive fish oil supplementation strategy in pregnancy for early childhood asthma/persistent wheeze during the first three years of life as we hypothesize that both…
- Conditions
- Asthma, Respiratory Tract Infections, Gastrointestinal Infection, Croup
- Trial name
- FREYA (NCT06560255)
- Testing
- n-3 fatty acid, Rape seed oil
- Where
- Denmark
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Professor Klaus Bønnelykke
Bronchiolitis Acute, Wheezing
The Role of Vitamin D and Vitamin D Receptor in Recurrent Wheezing in Children With Bronchiolitis: Immunological Association With T-lymphocyte Mitochondrial Mass
A prospective study will be conducted involving children under 2 years of age hospitalized for bronchiolitis during the period 2025-2026.
- Conditions
- Bronchiolitis Acute, Wheezing, RSV
- Trial name
- NCT07700134
- Testing
- No Intervention: Observational Cohort
- Where
- Greece
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Sleep Disordered Breathing, Sleep Hypopnea
Apnea Hypopnea Index Severity Versus Head Position During Sleep
This study evaluates the correlation of the position of the head during sleep, independent of the position of the torso, and the severity of apnea hypopneas in obstructive sleep apnea.
- Conditions
- Sleep Disordered Breathing, Sleep Hypopnea, Sleep Apnea, Sleep Apnea, Obstructive
- Trial name
- NCT04086407
- Testing
- Dual-axis inclinometer attached to the subject's forehead with tape
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Sleep Systems
Asthma
The Comparison of Electronic Auscultation Coupled With CALSA and FRI; Repeatability of FRI Biomarkers
CALSA will be compared with FRI and the repeatability of the FRI parameters will be tested in a group of healthy volunteers and asthma patients.
- Trial name
- NCT02228018
- Testing
- CT-scan
- Where
- Belgium
- Volunteers
- healthy volunteers welcome
- Sponsor
- FLUIDDA nv
Snoring
Pretreatment Assessment of Oropharynx Ans Soft Palate Radiofrequency Surgery - a Multi-center Study
Interstitial radiofrequency (RF) surgery of the soft palate (SP) is an established option in the treatment of habitual snoring. The decision making process in the management of habitual snoring would benefit from diagnostic…
- Trial name
- NCT01223859
- Testing
- Interstitial soft palate surgery
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Snoring, Sleep Apnea Syndromes
Clinical Study to Determine Safety and Effectiveness of KEEPASLEEP Device in Simple Snorers.
Study to demonstrate the safety and effectiveness of a new oral enhanced airway device to treat simple snoring.
- Trial name
- NCT00211627
- Testing
- KEEPASLEEP enhanced breathing device
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Miller, Chipp St. Kevin, M.D.
Wheezing
PREcision Medicine Directed Corticosteroids In Children With preSchool Wheeze
Young children frequently attend the emergency department (ED) with wheeze which is usually triggered by a virus infection, such as the common cold.
- Trial name
- PRECISE (NCT06580600)
- Testing
- Point of care respiratory virus testing
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Asthma, Bronchospasm
Epinephrine Inhalation Aerosol USP, a HFA-MDI Study for Assessment of Pharmacokinetics
This study examines the pharmacokinetic profile of Armstrong's proposed Epinephrine Inhalation Aerosol USP, an HFA-MDI (E004), using a stable isotope deuterium-labeled epinephrine (epinephrine-d3) to differentiate the…
- Conditions
- Asthma, Bronchospasm, Wheezing, Shortness of Breath
- Trial name
- NCT01188577
- Testing
- Epinephrine Inhalation Aerosol, HFA, Epinephrine Inhalation Aerosol
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Amphastar Pharmaceuticals, Inc.
Asthma, Cough
The Nature of Reflux-respiratory Symptoms Association in Difficult to Treat Wheezing\Coughing Babies
GER and respiratory symptoms are both common phenomenon in children. Both can coexist in the same patient by chance alone. Research reveals increased incidence for both to coexist leading to suspect a temporal association and…
- Conditions
- Asthma, Cough, Wheezing
- Trial name
- NCT00512382
- Testing
- WEEM - Wheezy Monitoring
- Where
- Israel
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Covid19
Cough Sound Recordings to Understand COVID-19-like Symptom Progression to Understand COVID-19-like Symptom Progression
Decentralized clinical study designed to collect further cough sounds, self-reported symptoms, and medical treatment questionnaires from participants enrolled on the COVID-Cough Study ("Study 1").
- Trial name
- NCT04989452
- Testing
- Recordings of cough sounds from adults
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- ResApp Health Limited
Obstructive Sleep Apnea
Acoustic OSA Prediction During Wakefulness and Monitoring During Sleep
The purpose of this study is to investigate the feasibility of sound analysis for: a) sleep apnea detection both during wakefulness and sleep, and b) flow-sound relationship during both wakefulness and sleep in patients and…
- Trial name
- NCT04112927
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Manitoba