Clinical trials: Respiratory Support
Ventilator-Induced Lung Injury
Pressure Support Ventilation During Laparoscopic and Abdominal Robotic Surgery.
This study is a single-center, blind, prospective, randomized, controlled trial of pressure support ventilation (PSVpro) versus pressure control ventilation - volume guaranteed (PCV - VG) during laparoscopic and robotic abdominal…
- Trial name
- NCT04815733
- Testing
- Mandatory ventilation, pressure support ventilation
- Where
- Russia
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Moscow Clinical Scientific Center
Sleep
A Dyadic Telehealth Program for Alzheimer's Patients/Caregivers
This study aims to refine and evaluate feasibility of a telehealth intervention for persons with Alzheimer's disease and their caregivers.
- Trial name
- NCT05102565
- Testing
- sleep education program
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Anxiety
Remote Social Support on Midwifery Students' Anxiety and Attitudes During Distance Education
The aim of this CT is to evaluate the effects of distance social support program on anxiety and attitudes towards distance education with midwifery students during COVID-19. The main questions are: 1.
- Trial name
- NCT06691789
- Testing
- Social support
- Where
- Turkey (Türkiye)
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Stress, Anxiety
The Wild Man Programme - a Nature-based Rehabilitation Enhancing Quality of Life for Men on Long-term Sick Leave
The aim of the present study is to examine whether the nature based 'Wild man Programme' can help to increase quality of life among men on sick leave compared to treatment as usual.
- Conditions
- Stress, Anxiety, Depression, Cardiac Disease
- Trial name
- NCT04073524
- Testing
- Nature-Body-Mind-Community, Treatment as usual
- Where
- Denmark
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Covid19 Vaccination, Vaccine Uptake
Supporting Audit and Feedback to Encourage Vaccine Uptake
In Ontario, approximately 6,000 family physicians can access a secure online system that provides a report that lists the COVID-19 vaccination status for each patient in their roster.
- Trial name
- NCT05099497
- Testing
- Using Practice Facilitators to Support Physicians
- Where
- Canada
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Women's College Hospital
Stress, Trauma
STEP: Building Trauma Resilience Among Nurses and Personal Support Workers During and Beyond COVID-19
The COVID-19 pandemic has amplified the need for skills training and mental health support for healthcare workers who are exposed to the numerous stressors and potential trauma of a high-risk environment.
- Conditions
- Stress, Trauma, Mental Health Issue, Healthcare Workers
- Trial name
- NCT04682561
- Testing
- Supportive Trauma Exposure Preparation Program
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Medication Adherence, Medication Compliance
Connected Healthcare for Individuals Living at Home With Chronic Conditions
Managing and taking medications as prescribed can be a difficult task. This is especially true for older adults living at home with chronic conditions while managing multiple prescribed medications.
- Conditions
- Medication Adherence, Medication Compliance, Medication Nonadherence, Hypertension
- Trial name
- NCT04339296
- Testing
- Spencer
- Where
- Canada
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Alberta Health Services, Calgary
COVID-19
A Clinical Trial to Determine the Safety and Efficacy of HB-adMSCs to Provide Protection Against COVID-19
Hope Biosciences is conducting a research study of an investigational product called autologous adipose-derived mesenchymal stem cells (abbreviated as HB-adMSCs) to provide immune support against COVID-19.
- Trial name
- NCT04349631
- Testing
- HB-adMSCs
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Hope Biosciences Research Foundation
Diarrhea Infectious, Seizures
Pilot Trial of a Clinical Decision-Support App for Managing Emergencies Among Clinicians in a Rural Ugandan Hospital
This study is testing a new mobile application called the OASES App, developed by the University of Milano-Bicocca. The App is designed to help frontline clinicians (nurses, clinical officers, and nursing assistants) provide…
- Conditions
- Diarrhea Infectious, Seizures, Emergency Care, Clinical Decision Support Systems
- Trial name
- OASES (NCT07257705)
- Testing
- OASES App
- Where
- Uganda
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca
Depression
Organized Self-Management Support Services for Chronic Depression
The purpose is to test the effectiveness of an organized care program for chronic or recurrent depression. Using a two-arm design, the investigators will randomly assign 300 participants with chronic or recurrent depression to…
- Trial name
- Stride (NCT01139060)
- Testing
- organized care program for chronic or recurrent depression
- Where
- 2 sites in United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Supraglottic Airway Obstruction, Airway Complication of Anesthesia
Wei Nasal Jet Tube vs Nasal Cannula Oxygen Support in Gastrointestinal Endoscopy Patients
Sedoanalgesia is applied to patients during gastrointestinal endoscopy. Sedoanalgesia may cause respiratory depression and hypoxia in patients.
- Conditions
- Supraglottic Airway Obstruction, Airway Complication of Anesthesia, Airway Obstruction, Anesthesia Complication
- Trial name
- NCT05783050
- Testing
- Wei Nasal Jet Tube, Nasal Cannula Oxygen Support
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Lung Cancer, Lung Diseases
A Clinical Study of LUNG-CT CAD Decision Support
This product is a computer-aided detection software designed to assist clinicians in detecting lung nodules in chest computer tomography.
- Trial name
- NCT05230563
- Testing
- Ti-LUNG
- Where
- Taiwan
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- TaiHao Medical Inc.
Any Single Gene Disorder (Cystic Fibrosis, Tay-Sachs)
Concurrent Single Gene and 24 Chromosome Aneuploidy Preimplantation Genetic Diagnosis (PGD)
Gene Security Network has developed a novel technology called Parental SupportTM (PS) which is used for Preimplantation Genetic Screening/Diagnosis (PGS/D) during in vitro fertilization (IVF).
- Trial name
- IVF008 (NCT01023048)
- Testing
- preimplantation diagnosis
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Natera, Inc.
Acute Respiratory Infection
ASPIRE I: Supporting Antibiotic Stewardship in Primary Care Via POCT
The ASPIRE study is an uncontrolled observational feasibility study, and a collaboration between the University of South Wales and Cwm Taf Morgannwg University Health Board (CTMUHB).
- Trial name
- ASPIRE I (NCT06912022)
- Testing
- FebriDx Device
- Where
- 2 sites in United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of South Wales
Child Behavior Problem, Mental Health Issue
Supporting Parents & Kids Through Lockdown Experiences (SPARKLE).
Throughout the COVID-19 pandemic, reduced access to childcare, money- and health-related worries and extended confinement and social isolation have placed great pressure on many families.
- Trial name
- SPARKLE (NCT04786080)
- Testing
- Parent Positive
- Where
- United Kingdom
- Volunteers
- 646 people, healthy volunteers welcome
- Sponsor
- King's College London
Wellness, Burnout, Caregiver
Evaluating the Impact of Resource Navigators to Support LTC and RH Staff During and Beyond COVID-19
The goal of this clinical trial is to test how well resource navigators help long-term care and retirement home staff access the various health and wellness resources available to them and the effects that this has on their…
- Conditions
- Wellness, Burnout, Caregiver, Burnout, Professional, COVID-19
- Trial name
- NCT05677997
- Testing
- Intervention
- Where
- Canada
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Thalassemia Major, Covid19
Frequency of COVID-19 Antibodies in Patients With Hereditary Hematological Diseases
In Italy there are about 5000 patients with dependent transfusion thalassemia (source Italian Thalassemia and Hemoglobinopathies - SITE) and a smaller number, currently not definable, of patients with sickle cell anemia in…
- Trial name
- ThalaCoV (NCT04526405)
- Testing
- SARS-CoV-2 S1/S2 IgG
- Where
- Italy
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca
Influenza, COVID-19
Commercially Available Cannabis Products for Immune Support
This study will be a prospective observation of the use of commercially available hemp and cannabis products marketed for immune support.
- Conditions
- Influenza, COVID-19, Common Cold
- Trial name
- NCT05944705
- Testing
- Immune Support Supplement
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Center For Interventional Pain and Spine
COVID-19
CONFIDENT: Supporting Long-term Care Workers During COVID-19
The CONFIDENT Study is an online three-arm randomized trial that aims to help long-term care workers in the United States feel more confident about the Coronavirus Disease 2019 (COVID-19) vaccines.
- Trial name
- NCT05168800
- Testing
- Dialogue-Based Webinar, Social Media Website, Enhanced Usual Practice
- Where
- United States
- Volunteers
- 2,634 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
COVID19, Hydroxychloroquine
Protect: Study With Hydroxychloroquine for Prevention and Early Phase Treatment of Coronavirus Disease (COVID-19)
This is a Italian, superiority, open label cluster-randomised, interventional clinical trial aimed at assessing whether the treatment with Hydroxychloroquine can reduce the percentage of symptomatic subjects compared to…
- Conditions
- COVID19, Hydroxychloroquine, Prophylaxis, Treatment
- Trial name
- PROTECT (NCT04363827)
- Testing
- Hydroxychloroquine
- Where
- Italy
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Istituto Romagnolo per lo Studio dei Tumori Dino Amadori IRST S.r.l. IRCCS