Clinical trials: Respiratory System Disease
IBD, Covid19
Covid-19 Vaccine Responses in Patients With Inflammatory Bowel Diseases
The 2019-coronavirus disease (COVID-19), caused by SARS-CoV-2, was identified as the source of pneumonia cases in Wuhan city in China. It rapidly spread worldwide and was declared by WHO as a pandemic.
- Trial name
- NCT05067959
- Testing
- Covid-19 vaccine
- Where
- Israel
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Cerebral Palsy, Spastic
The Relationship Between Functional Exercise Capacity, Respiratory Muscle Strength, Trunk Control, Balance and Activities of Daily Living in Individuals With Cerebral Palsi
Cerebral palsy (CP) causes problems in posture, movement, breathing, postural control and balance in individuals. This work; This study was conducted to examine the relationship between functional exercise capacity, respiratory…
- Trial name
- NCT05682079
- Testing
- TCMS, PEDİ, respiration, GMFCS,PBS,functional capacity
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Nursena Güçlü
Sars-CoV2, COVID19
A Study of Hydroxychloroquine and Zinc in the Prevention of COVID-19 Infection in Military Healthcare Workers
A multicenter randomized clinical trial aiming to assess the efficacy of hydroxychloroquine associated to Zinc compared to hydroxychloroquine, in the prevention of Military Health Professionals Exposed to SARS CoV2 in Tunisia
- Trial name
- COVID-Milit (NCT04377646)
- Testing
- Hydroxychloroquine, Zinc
- Where
- Tunisia
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Military Hospital of Tunis
Vaccination
P3+ Intervention Phase
This study will address vaccine uptake both for pregnant women and for their children, through 20 months of age, to test the hypothesis that exposure to the P3+ intervention package will increase the likelihood a pregnant woman…
- Trial name
- NCT02898688
- Testing
- Control Site, Intervention Site, Patient-level Control Group
- Where
- 23 sites in United States
- Volunteers
- 2,200 people, healthy volunteers welcome
- Sponsor
- Emory University
Cystic Fibrosis
Upper Extremity Exercise Capacity, Muscle Oxygenation, Balance in Patients With Cystic Fibrosis
The primary aim of the study is to evaluate upper extremity exercise capacity, muscle oxygenation, balance and physical activity level in patients with cystic fibrosis..
- Trial name
- NCT04803643
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Gingivitis; Chronic
Zinc Stents for the Treatment of Gingivitis
Background This study investigates the effects of zinc-containing stents on gingival inflammation, bleeding, and plaque regrowth in gingivitis patients.
- Trial name
- NCT06888440
- Testing
- scaling and zinc stents
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Patient-Ventilator Interaction, Asynchrony, Patient-Ventilator
Standardising Terminology, Classification, Diagnostic Recognition and Reporting of Patient-ventilator Interactions: Protocol for an International Delphi Consensus Study
Patient-ventilator interaction describes how a mechanically ventilated patient's breathing effort aligns with ventilator support.
- Trial name
- INTERACT (NCT07638540)
- Testing
- Modified Delphi consensus survey
- Where
- Kuwait
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Al Adan Hospital Kuwait
Rhinitis, Allergic, Perennial, Rhinitis, Allergic, Seasonal
Effect of a 10,000 EU Dose of Endotoxin in Allergic and Mildly Asthmatic Adults
The purposes of this pilot safety study are to identify a dose of inhaled Clinical Center Reference Endotoxin (CCRE) that is well tolerated by allergic subjects that induces measurable increases in neutrophil content of induced…
- Conditions
- Rhinitis, Allergic, Perennial, Rhinitis, Allergic, Seasonal, Asthma
- Trial name
- NCT00839189
- Testing
- Clinical Center Reference Endotoxin (CCRE)
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Covid19
Vaccination With COMIRNATY in Subjects With a VAXZEVRIA First Dose
CombiVacS is a phase 2 randomized, adaptive trial developed to evaluate the immunogenicity of a dose of COMIRNATY after a previous single dose of VAXZEVRIA.
- Trial name
- CombiVacS (NCT05378191)
- Testing
- COMIRNATY
- Where
- 5 sites in Spain
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Asthma, Vitamin D Resistant Rickets
Assessment Of Vitamin D Role In The Pathogenesis Of Asthma In Vitamin D Resistent Patients
Research Title: Evaluation of airway reactivity, allergy and inflammatory mediators in exhaled breath condensate in vitamin D resistant rickets.
- Trial name
- NCT01578824
- Testing
- Methacholine Challenge Test
- Where
- Israel
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Spinal Cord Injury
Respiratory Motor Control and Blood Pressure Regulation After Spinal Cord Injury
The proposed study is designed to answer a novel research question: Can resistive respiratory muscle training designed to improve respiratory motor control also improve blood pressure regulation impaired by spinal cord injury?…
- Trial name
- NCT02396823
- Testing
- Respiratory Muscle Training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Diphtheria, Tetanus
Antibody Persistence in Healthy Children After Primary and Booster DTaP-IPV-Hep B-PRP-T Vaccine or Control Vaccine
The purpose of this study is to evaluate the long term immunogenicity produced in children by the investigational hexavalent vaccine (DTaP-IPV-Hep B-PRP-T) given in Study A3L15 (NCT 00362336).
- Conditions
- Diphtheria, Tetanus, Whooping Cough, Hepatitis B
- Trial name
- NCT01105559
- Where
- 2 sites in South Africa
- Volunteers
- 455 people, healthy volunteers welcome
- Sponsor
- Sanofi
COVID-19
Clinical Validation of Breath Analyser Tests for Diagnosis of COVID-19.
The Sponsor has developed a rapid screening tool intended to determine if the subject tested is COVID-19-free (Negative to COVID-19).
- Trial name
- NCT05094674
- Testing
- Breath Sample analysis
- Where
- United Kingdom
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Tera Group
Refractory Chronic Cough
Effect of Gefapixant (MK-7264/AF-219) on Cough Reflex Sensitivity in Healthy and Chronic Cough Participants (MK-7264-014)
The primary objective of this study was to assess the effect of a single dose of gefapixant 100 mg on cough reflex sensitivity to various challenge agents (capsaicin, citric acid, adenosine triphosphate [ATP], and distilled…
- Trial name
- NCT02476890
- Testing
- Gefapixant 100 mg
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Afferent Pharmaceuticals, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
COVID-19 Vaccines, COVID-19 Pandemic
Getting to Yes, Michigan! (G2YMI)
This study entitled Community-Centered Interventions for Improved Vaccine Uptake for COVID-19 (CIVIC): Getting to Yes, Michigan!, is designed to increase vaccine uptake among populations that experience COVID-19 related…
- Trial name
- G2YMI (NCT05096260)
- Testing
- Motivational Interviewing based SMS/MMS and web content
- Where
- United States
- Volunteers
- 1,180 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Hypoxic-Ischemic Encephalopathy
A Study of a Blood Marker in Newborns With Brain Injury Caused by Lack of Oxygen at Birth
Perinatal asphyxia is a significant health problem with an incidence of 1 to 8 per 1,000 live births and can lead to serious morbidity and mortality during the neonatal period.
- Trial name
- NCT07292220
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mustafa Gürkan
Vaccination Reaction
Safety, Tolerability, Immunogenicity and Immunological Mechanisms of TETRALITE, a Novel Seasonal Influenza Vaccine
The effect of LiteVax Adjuvant supplemented to licensed seasonal influenza vaccine on safety and immunogenicity will be investigated in both younger and older healthy participants.
- Trial name
- TETRALITE-Ib (NCT06294262)
- Testing
- TETRALITE
- Where
- Belgium
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- LiteVax BV
Pneumococcal Infections
Phase I Clinical Trial of a Candidate PCV13 in Healthy People
Streptococcus pneumoniae is a major cause of morbidity and mortality in children worldwide, resulting in up to 1 million pediatric deaths every year.
- Trial name
- NCT05602480
- Testing
- 13-Valent Pneumococcal Polysaccharide Conjugate Vaccine
- Where
- China
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Wuhan BravoVax Co., Ltd.
Stereotype-threat, COVID-19
Stereotype Threat Effect on CPR Performance in Covid-19 Intensive Care Units: A Randomised Controlled Mannequin Study
Stereotype threat (ST) is an important issue that has been studied repeatedly in the psychology literature. ST is the thought that a person will be negatively evaluated and judged regarding a negative stereotype that belongs to…
- Trial name
- NCT05074446
- Testing
- stereotype threat manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Sleep Deprivation, Hypoxia
Effect of Acute Sleep Restriction on Responses to Hypoxia
At altitude, humans are exposed to environmental hypoxia induced by the decrease in barometric pressure. On duty or in training, mountain troops, paratroopers or aircrew are regularly exposed to altitude.
- Trial name
- HypSom (NCT05563688)
- Testing
- Hypoxia exposure, Sleep deprivation, Cognitive tasks
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.