Clinical trials: Resuscitations
Cardiac Arrest, Postresuscitation Encephalopathy
Prehospital Non-invasive Cooling of Comatose Patients After Cardiac Arrest
Single centre randomized controlled two arm clinical trial of patients after out of hospital cardiac arrest with return of spontaneous circulation.
- Trial name
- NCT03829215
- Testing
- CAERVest cooling device
- Where
- Austria
- Sponsor
- Medical University of Vienna
Depressive Disorder
Effect of the Addition of Ketamine to Sevoflurane Anesthesia in Electroconvulsive Therapy
The investigators evaluate the effects of a subanesthetic dose of ketamine, administered as an adjunct to sevoflurane, on duration of seizure activity, hemodynamic profile and recovery times during electroconvulsive therapy (ECT)…
- Trial name
- NCT02267980
- Testing
- Sevoflurane, Ketamine, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Inonu University
Basic Life Support
Pedagogical Aspects on Training in Basic Life Support
Cardio vascular disease (CVD) including out-of-hospital cardiac arrest (OHCA) is still the leading cause of death in a global perspective.
- Trial name
- NCT03618888
- Testing
- Instructor-led training, Self-learning training
- Where
- Sweden
- Volunteers
- 2,623 people, healthy volunteers welcome
- Sponsor
- University of Boras
Cardiopulmonary Arrest
SNPeCPR In Cardiac Arrest REsuscitation
Approximately 50,000 patients are victims of out of hospital cardiac arrest every year in France. Despite cardiopulmonary resuscitation (CPR) and many studies on the topic resuscitation survival after cardiac arrest remains low…
- Trial name
- SICARE (NCT02225561)
- Testing
- pharmaco- mechanical optimization, mechanical optimization only
- Where
- France
- Volunteers
- 1 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Out-of-Hospital Cardiac Arrest, Pulmonary Ventilation
CAvent-Ventilation During Advanced Cardiopulmonary Resuscitation in Out-of-hospital Cardiac Arrest- an Observational Study
The aim of this observational study is to investigate how ventilations is given during cardiopulmonary resuscitation (CPR) given by advanced life support providers (ALS).
- Trial name
- CAvent (NCT04237727)
- Testing
- Fluxmed GrH portable pneumotachograph
- Where
- 5 sites in Netherlands, Sweden
- Volunteers
- 241 people
- Sponsor
- Uppsala University
Critical Care, Fluid Resuscitation
The Fluid Translation of Research Into Practice Study
Translating reliable evidence on fluid resuscitation of intensive care patients into clinical practice - Improving patient outcomes and containing public health costs
- Trial name
- Fluid-TRIPS (NCT02002013)
- Where
- Australia
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- The George Institute for Global Health, Australia
Acute Lung Injury, Adult Respiratory Distress Syndrome
Airway Pressure Release Ventilation (APRV) Compared to ARDSnet Ventilation
Traditional modes of ventilation have failed to improve patient survival. Subsequent observations that elevated airway pressures observed in traditional forms of ventilation resulted in barotrauma and extension of ALI lead to the…
- Conditions
- Acute Lung Injury, Adult Respiratory Distress Syndrome, Kidney Injury
- Trial name
- PRESSURE (NCT00793013)
- Testing
- Volume-Cycled Assist-Control (AC) mode, Airway Pressure Release Ventilation (APRV) mode
- Where
- United States
- Sponsor
- University of Tennessee, Chattanooga
Cardiopulmonary Arrest, VA-ECMO
Optimized CT-imaging Protocol in VA-ECMO Patients After CPR
Veno-arterial (VA) extracorporal membrane oxygenation (ECMO) is an increasingly applied method in patients under cardiopulmonary resuscitation (CPR), who are regularly examined with a contrast-enhanced computed tomography to…
- Trial name
- NCT05290805
- Testing
- ECMO flow rate reduction
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Atrial Fibrillation, Assessment of Serious Advers Events
Prospective Registration and Assessment of Serious Adverse Events Within the AFNET
Prospective registration and independent assessment of SAE associated with atrial fibrillation such as thromboembolic events, and other cardiac and noncardiac complications by a Critical Event Committee.
- Conditions
- Atrial Fibrillation, Assessment of Serious Advers Events, Thromboembolic and Bleeding Complications, Complications of Antiarrhythmic Drugs or Invasive Procedures
- Trial name
- AFNET A7 (NCT01678456)
- Where
- Germany
- Volunteers
- 13,000 people
- Sponsor
- Atrial Fibrillation Network
Resuscitation, Chest Compression
How to Learn Cardiopulmonary Resuscitation
the aim of the study is to evaluate two methods of teaching cardiopulmonary resuscitation in the context of chest compression quality.
- Conditions
- Resuscitation, Chest Compression, Quality
- Trial name
- NCT04039997
- Testing
- CPRMeter, Manual chest compression
- Where
- Poland
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Lazarski University
Septic Shock
Effect of EGDT on Hepatic Perfusion in Patients With Septic Shock
To observe the effect of early goal directed therapy (EGDT) on hepatic perfusion in patients with septic shock. Hypothesis: Hepatic perfusion did not improved after EGDT in patients with septic shock.
- Trial name
- NCT02060773
- Where
- China
- Sponsor
- Zhongda Hospital
Heart Arrest, Out-Of-Hospital, CardioPulmonary Resuscitation
Ventilation in Cardiac Arrest Resuscitation Study
Out-of-hospital cardiac arrest (OHCA) is a major public health problem, with around 40,000 victims each year in France. Their survival rate remains dramatically low, at less than 10%.
- Conditions
- Heart Arrest, Out-Of-Hospital, CardioPulmonary Resuscitation, Basic Cardiac Life Support
- Trial name
- VECARS (NCT05992454)
- Testing
- EOLIFE
- Where
- France
- Volunteers
- 120 people
- Sponsor
- French Defence Health Service
Shock
Emergency Department (ED) Flow-directed Fluid Optimization Resuscitation Trial (EFFORT)
The short term goal of this study is to evaluate a non-invasive approach that optimizes intravenous (IV) fluid administration according to heart performance and results in surrogate improvements in morbidity and mortality via…
- Trial name
- EFFORT (NCT01128413)
- Testing
- Cheetah NICOM® PLRT, USCOM ® (Ultrasound Cardiac Output Monitor), Inferior Vena Cava (IVC) Ultrasound Collapsibility
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Washington University School of Medicine
Cardiopulmonary Arrest
REBOA in Nontraumatic OHCA
The investigators propose a multicenter randomized controlled trial in South Korea and Taiwan to observe the clinical effects of REBOA on nontraumatic out-of-hospital-cardiac-arrest (OHCA) patients.
- Trial name
- REBOA (NCT06031623)
- Testing
- REBOA
- Where
- South Korea
- Volunteers
- 234 people
- Sponsor
- Seoul National University Hospital
In-hospital Cardiac Arrest
Coverage and Validity of the Swedish Registry of Cardiopulmonary Resuscitation Regarding In-hospital Cardiac Arrest
The study will have an observational retrospective cross-sectional design. Patient records and hospital administrative systems at 10 hospitals in Sweden will be searched using ICD-codes to find all patients treated for an…
- Trial name
- NCT05184972
- Where
- Sweden
- Volunteers
- 1,109 people
- Sponsor
- Dalarna University
Colon Surgery
Impact of Intravascular Fluid Resuscitation and Whole Blood Viscosity for Colon Surgery
After obtaining approval from the Institutional Review Board of our institution, written informed consent is obtained from patients undergoing colon surgery are enrolled in this prospective study and randomly allocated into one…
- Trial name
- NCT02770027
- Testing
- Intravenous Crystalloid, Intravenous HES
- Volunteers
- 30 people
- Sponsor
- Konkuk University Medical Center
Norepinephrine, Hemorrhagic Shock
Norepinephrine in Preperiod of Hypotensive Resuscitation in Hemorrhagic Shock
The aim of this work was to investigate the effects of low dose of norepinephrine in preperiod of hypotensive resuscitation in hemorrhagic shock.
- Conditions
- Norepinephrine, Hemorrhagic Shock, Hypotensive Resuscitation
- Trial name
- NCT06311903
- Testing
- Low dose of Norepinephrine (NE), High dose of Norepinephrine (NE)
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Tanta University
Cardiopulmonary Arrest With Successful Resuscitation
Cardiopulmonary Resuscitation Self-training
Participants were 45 first-year medical students randomly assigned to cardiopulmonary resuscitation (CPR) self-training using either a video-based presentation or a serious game developed in a 3D learning environment for up to 20…
- Trial name
- NCT03729037
- Testing
- CPR self-training
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Cardiac Arrest
Endotracheal Intubation Using Three Laryngoscopes in Maternal Cardiac Arrest: a Manikin Simulation Study
European Resuscitation Council (ERC) Guidelines for Resuscitation 2010 emphasize high quality chest compressions .They propose minor changes for pregnant women: manual left deviation of the uterus or a left-lateral incline of…
- Trial name
- NCT02074072
- Testing
- 15 degree left-lateral tilt wedges, 30 degree left-lateral tilt wedges
- Where
- South Korea
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Hanyang University Seoul Hospital
Neonatal Resuscitation
Doppler Ultrasound Compared With Stethoscope to Assess Heart Rate (HR)
This is a prospective randomized controlled trial comparing heart rate measurement by Doppler ultrasound or auscultation with a stethoscope in newborn infants who require stabilization or resuscitation immediately after birth.
- Trial name
- NCT04242654
- Testing
- Handheld fetal doppler ultrasound
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Columbia University
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