Clinical trials: Resuscitations
Cardiopulmonary Resuscitation, Cardiac Arrest
Cardiac Arrest Bundle of cARE Trial
An out-of-hospital cardiac arrest is a sudden event where the heart stops beating and a person becomes unresponsive. During this event, vital organs in the body receive no blood flow, causing them to shut down.
- Conditions
- Cardiopulmonary Resuscitation, Cardiac Arrest, Out of Hospital Cardiac Arrest
- Trial name
- CABARET (NCT05917717)
- Testing
- Neuroprotective 'bundle of care'
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Hemorrhagic Shock
Efficacy, Safety of Solution Containing Hyperosmolar Sodium Lactate Infusion for Resuscitation of Patients With Hemorrhagic Shock
Indication: Resuscitation in pts with hemorrhagic shock due to multiple injuries Prospective, open label RCT in pts. with traumatic hemorrhagic shock in RS Hasan Sadikin Hospital, Indonesia. PI: Dr.
- Trial name
- NCT01433276
- Testing
- Hyperosmolar sodium lactate, Ringer's lactate
- Where
- Indonesia
- Volunteers
- 71 people
- Sponsor
- Innogene Kalbiotech Pte. Ltd
Advance Directives, Resuscitation Orders
Patient Understanding of End of Life Care
This study aims at assessing factors that affect patient choices for end of life care. 300 patients would be assigned either to a control arm (questionnaire alone) or intervention arm (standardized explanation+ questionnaire).
- Trial name
- NCT01683097
- Testing
- Standardized explanation
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Partners in Internal Medicine
Vital Signs
The Effect of Postnatal Lying Position on Cerebral Oxygenation in Newborns
In the international delivery room guidelines, it is not specified which position is optimal for the baby stabilization. Here, the investigators want to evaluate the effects of the positions on postnatal adaptation and cerebral…
- Trial name
- NCT05868980
- Testing
- vital signs by postpartum position
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr. Behcet Uz Children's Hospital
Neonatal Disorder, Asphyxia Neonatorum
Early or Late Cord Clamping in the Depressed Neonate
This study evaluates the hypothesis that delayed compared to early umbilical cord clamping will improve neonatal transition in terms of circulation and breathing during resuscitation.
- Trial name
- NepCordIII (NCT02727517)
- Testing
- Early (≤ 60 seconds) cord clamping, Delayed (≥ 180 seconds) cord clamping
- Where
- Nepal
- Volunteers
- 90 people
- Sponsor
- Uppsala University
Education Advancement
Airway Obstruction During BLS
Appropriate management of cardiac arrest (immediately and technically well performed) is a priority that must be taught to all citizens and future healthcare personnel, including future physicians.
- Trial name
- BLS-OBST (NCT06770920)
- Testing
- use of an observer tool when not role-playing
- Volunteers
- 112 people
- Sponsor
- Université Paris-Sud
Resuscitation, Outcome, Fatal
Outcome After Out of Hospital Cardiac Arrest in Bern, Switzerland
Sudden cardiac arrests is one of the most frequent causes of death. In Switzerland every year 8000-10.000 people suffer from a cardiac arrest.
- Conditions
- Resuscitation, Outcome, Fatal, Out-Of-Hospital Cardiac Arrest
- Trial name
- NCT03759210
- Where
- Switzerland
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cardiac Arrest, Postresuscitation Encephalopathy
Prehospital Non-invasive Cooling of Comatose Patients After Cardiac Arrest
Single centre randomized controlled two arm clinical trial of patients after out of hospital cardiac arrest with return of spontaneous circulation.
- Trial name
- NCT03829215
- Testing
- CAERVest cooling device
- Where
- Austria
- Sponsor
- Medical University of Vienna
Cardiopulmonary Resuscitation
Pulse Control Using USG and Manual Palpation Methods in Cardiopulmonary Resuscitation
The final approach adopted in Advanced Cardiac Life Support (ACLS) guidelines as defined by the American Heart Association (AHA) and the European Resuscitation Council (ERC) is to minimize the time between chest compressions in…
- Trial name
- NCT05557032
- Testing
- cardiopulmonary resuscitation
- Where
- Turkey (Türkiye)
- Volunteers
- 536 people
- Sponsor
- Izmir Katip Celebi University
Organophosphate Poisoning
Adding Nebulized Salbutamol to Intravenous Atropine and Oxygen in OP Poisoning
We hypothesize that salbutamol will speed removal of alveolar fluid compared to atropine alone in OP poisoned patients. We propose to compare the effect of two stat doses of nebulized salbutamol (2.5 mg; 5.0 mg), with nebulized…
- Trial name
- SalbutamolOP (NCT02160548)
- Testing
- Standard care, Standard care+ 2.5 mg Salbutamol, Standard care+ 5 mg Salbutamol
- Where
- Bangladesh
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Sylhet M.A.G.Osmani Medical College
Out-Of-Hospital Cardiac Arrest, Cardiac Arrest
Steroid Treatment After Resuscitated Out-of-Hospital Cardiac Arrest
Comatose patients resuscitated from Out-of-Hospital Cardiac Arrest (OHCA) often develop a complicated systemic inflammatory response and have a poor prognosis with neurological damage being the most common cause of death.
- Conditions
- Out-Of-Hospital Cardiac Arrest, Cardiac Arrest, Cardiac Arrest With Successful Resuscitation, Post Cardiac Arrest Syndrome
- Trial name
- STEROHCA (NCT04624776)
- Testing
- Methylprednisolone, Isotonic saline
- Where
- 2 sites in Denmark
- Volunteers
- 158 people
- Sponsor
- Christian Hassager
Simulation Training
Effect of the Use of a Visual Feedback Device in RCP Trainings
To verify the efficacy of manikins with feedback in the training of physicians and nurses in the courses of Advanced Cardiac Life Support (ACLS) authorized by the American Heart Association (AHA) when compared to the traditional…
- Trial name
- NCT04338490
- Testing
- Feedback mannequim
- Where
- Brazil
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Cardiac Arrest (CA)
Incidence of Colon Ischemia in Patients After Cardiopulmonary Resuscitation (CPR)
Bedside colonoscopy 24-36 hours after successful CPR
- Trial name
- NCT07359313
- Testing
- colonoscopy
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital Freiburg
Pregnancy Preterm, Premature Birth
The Periviable GOALS Decision Support Tool
The Periviable GOALS (Getting Optimal Alignment around Life Support) decision support tool (DST) is meant to facilitate informed shared decision-making regarding neonatal resuscitation for families facing the threat of a…
- Conditions
- Pregnancy Preterm, Premature Birth, Pregnancy Complications, Obstetric Labor, Premature
- Trial name
- NCT05264779
- Testing
- Periviable GOALS DST
- Where
- 12 sites in United States
- Volunteers
- 300 people
- Sponsor
- Indiana University
Acute Coronary Syndrome
Effects and Plasma Concentration of Ticagrelor, After Crushed and Non-crushed Intake, After Acute Coronary Syndrome
The first aim of the study is to prove that after starting the therapy with crushed tablets, the platelet inhibition will be as expected after starting therapy with intact tablets. Gurbel et al.
- Trial name
- ticagrelor (NCT02341729)
- Testing
- ticagrelor
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- University Hospital, Ghent
Hypovolemia
Plasma-Lyte 148® versUs Saline Study
The aim of PLUS is to conduct a multi-centre, blinded, randomised, controlled trial (RCT) to determine whether fluid resuscitation and therapy with a "balanced" crystalloid solution (Plasma-Lyte 148®) decreases 90-day mortality…
- Trial name
- PLUS (NCT02721654)
- Testing
- Plasma-Lyte 148®, 0.9% sodium chloride
- Where
- 51 sites in Australia, New Zealand
- Volunteers
- 5,037 people
- Sponsor
- The George Institute
ARDS, Human, Catheter Infection
Prone Position Impact in ARDS Patients on the Incidence of Central Venous Catheter Colonization
Catheter colonization, catheter-associated infection and catheter-associated bacteremia are a major challenge for resuscitation unit.
- Trial name
- ILCDV (NCT03405038)
- Where
- France
- Volunteers
- 202 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Infant, Premature, Diseases, Birth, Preterm
The NEU - CAP Trial
The aim of NEU-CAP is to investigate the clinical impact of using a colorimetric carbon dioxide (CO₂) detector during non-invasive ventilation (NIV). Infants born before 32 weeks of gestation will be included in this trial.
- Conditions
- Infant, Premature, Diseases, Birth, Preterm, Respiratory Distress Neonatal
- Trial name
- NEU-CAP (NCT07754032)
- Testing
- Local standard care of monitoring non-invasive ventilation, CO₂-guided Non-Invasive Ventilation
- Volunteers
- 1,860 people
- Sponsor
- Leiden University Medical Center
Resuscitation, Cardiopulmonary
Effect of Early High-dose Epoetin Alfa During Cardiac Arrest (Pilot Study)
The purpose of this study is to test the possible neuroprotective effect of early high dose erythropoietin alpha after out of hospital cardiac arrest (OHCA).
- Conditions
- Resuscitation, Cardiopulmonary, Cardiac Arrest
- Trial name
- NCT00719498
- Testing
- Epo-alpha
- Volunteers
- 20 people
- Sponsor
- Janssen Cilag S.A.S.
Cardiopulmonary Resuscitation, Personal Protective Equipment
Effect of Wearing Personal Protective Equipment (PPE) on CPR Quality in Times of the COVID-19-pandemic
Background The significant risk of transmission of SARS-CoV-2 to healthcare staff mandated changes to Basic and Advanced Life Support (BLS and ALS) guidelines.
- Trial name
- NCT04548934
- Testing
- Personal protective equipment (PPE), No Personal protective equipment (PPE)
- Where
- Italy
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Institute of Mountain Emergency Medicine
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