Clinical trials: Retreatment
This Study Will be Performed to Evaluate the Efficiency of 810 nm Diode Laser Disinfection on Periapical Healing in Root Canal Retreatment Cases
The Efficiency of 810 nm Diode Laser on Periapical Healing After Root Canal Retreatment
The main cause of endodontic disorders is microbial infection. From the infected root canal, microorganisms can penetrate into the deeper layers of root dentine and propagate a periapical tissue through the apical foramen and…
- Trial name
- Retreatment (NCT07194837)
- Testing
- diode laser, Calcium Hydroxide (Ca(OH)2)
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Helicobacter Pylori
The Study on the Selection of Time for Retreatment of Helicobacter Pylori After Eradication Failure
The patients who accepted the quadruple eradication program of the helicobacter pylori but failed to eradicate helicobacter pylori will be assessed the most suitable re-eradication time of helicobacter pylori.
- Trial name
- NCT04810793
- Testing
- Amoxicillin , Levofloxacin and Esomeprazole, Amoxicillin , Furazolidone and Esomeprazole, Tetracycline , Furazolidone and Esomeprazole
- Where
- China
- Volunteers
- 820 people, healthy volunteers welcome
- Sponsor
- Shandong University
Crohn Disease
The Intensive Post Exclusive Enteral Nutrition Study
Crohn's disease (CD) is a chronic inflammatory condition with phases where the disease is active and other, where there are no symptoms.
- Trial name
- iPENS (NCT04225689)
- Testing
- CD-TREAT diet
- Where
- 5 sites in United Kingdom
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Microbial Colonization
Rewilding the Human Gut: Reintroduction of the Species Limosilactobacillus Reuteri
The large intestine is home to trillions of microbes, known as the gut microbiome, which perform essential functions, such as digesting food and fighting disease.
- Trial name
- NCT03501082
- Testing
- L Reuteri PB-W1 Strain, L. Reuteri DSM20016T Strain, Non-Industrialized-Type Diet
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Endodontic Inflammation
Evaluation of the Effect of Different Irrigation Activation Methods During Endodontic Retreatment
The persistent and secondary intraradicular infections are the primary causes of post-treatment disease following endodontic treatment of any tooth.
- Trial name
- NCT07779148
- Testing
- Xp Finisher R file
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Minia University
Root Canal Infection, Periapical; Infection
Bacteria Elimination in Retreatment Cases Using Different Disinfection Techniques
Nonsurgical root canal retreatment may become essential when the initial endodontic treatment fails because of the persistent intracanal or extracanal infections.It has been stated that the one of the main cause of posttreatment…
- Trial name
- NCT03750162
- Testing
- VDW Ultra, AMD picasso, ProtaperNext X3 gutta-percha
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Postoperative Pain
Effect of EDDY and Manual Dynamic Activation Techniques on Postoperative Pain in Retreatment
The aim of the study was to evaluate the effectiveness of EDDY and manual dynamic activation (MDA) techniques on postoperative pain (PP) associated in retreatment.
- Trial name
- Pain (NCT04726670)
- Testing
- Evaluation of postoperative pain
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Healthy
Examine Plasma Concentrations of Buprenorphine Following Reapplication of Buprenorphine Transdermal System (BTDS) After Variable Application Site Rest Periods
The purpose of this study is to determine the pharmacokinetics of BTDS following same-site patch reapplication after rest intervals.
- Trial name
- NCT01259102
- Testing
- Buprenorphine transdermal patch
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Purdue Pharma LP
Pain, Postoperative
Hand and Engine-driven Techniques for Endodontic Retreatment
Numerous instrumentation techniques have been suggested for the nonsurgical retreatment of teeth with primary failure of endodontic therapy in laboratory studies.
- Trial name
- NCT03743233
- Testing
- Hand file, Reciprocating
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Root Canal Infection, Periapical Diseases
Calcium Silicate Sealer-based Obturation in Root Canal Retreatment
This study will evaluate the outcome of calcium silicate sealer-based obturations in root canal retreatment.
- Trial name
- NCT05714384
- Testing
- CeraSeal (Calcium Silicate-based Root Canal Sealer)
- Where
- Kuwait
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Kuwait
Root Canal Infection
Evaluation of Post Operative Pain in Retreatment of Molars Using Different Irrigant
This study evaluates the efficacy of dexamethasone as a intracanal irrigant along with sodium hypochlorite 1% and 5.25% concentrations in post treatment pain for molar root canal retreatment.
- Trial name
- NCT04250519
- Testing
- Sodium Hypochlorite
- Where
- India
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tamil Nadu Dr.M.G.R.Medical University
Apical Periodontitis
Effects of PDT and Bioceramic Filling on Periapical Healing and Postoperative Pain After Endodontic Retreatment
The purpose is to investigate influence of bioceramic filling of the root canal and photodynamic therapy on periapical healing and development of postoperative pain after endodontic retreatment.
- Trial name
- NCT04072926
- Testing
- BioRoot
- Where
- Croatia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Medical Innovation Center Wroclaw
Metastatic Colorectal Cancer
FOLFOX + Panitumumab According to a "Stop and go" Strategy With a Reintroduction Loop After Progression on Fluoropyrimidine as Maintenance Treatment, as the First Line in Patients With Metastatic Colorectal Adenocarcinoma Without a RAS Mutation
Single-arm, multi-centre phase II study The primary objective is to evaluate the time to failure of the strategy.
- Trial name
- OPTIPRIME (NCT03584711)
- Testing
- FOLFOX + panitumumab
- Where
- 124 sites in France, Martinique
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Federation Francophone de Cancerologie Digestive
Endodontically Treated Teeth, Post Operative Pain
Bioceramics Pain Control
Postoperative pain in endodontic retreatment cases presents a challenge to any endodontist. Tricalcium silicate materials as mineral trioxide aggregate (MTA) and bioceramics have shown favorable periapical tissue reactions and…
- Trial name
- NCT05399303
- Testing
- obturation
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Misr International University
Intervention Studies, ASA Physical Status I
Biological, Radiographic and Clinical Evaluation of Various Inter-Visit Root Canal Dressings in Retreatment Cases
The aim of this clinical trial is to evaluate anti-inflammatory effect of various intracanal medications: 1. Calcium Hydroxide Slurry mixed with 3% Sodium Hypochlorite 2. Calcium Silicate 3.
- Conditions
- Intervention Studies, ASA Physical Status I, Intracanal Medication, Periapical Abscess
- Trial name
- RCT (NCT07641933)
- Testing
- Calcium Silicate Intracanal Medication, Calcium Hydroxide Slurry mixed with Sodium Hypochlorite Intracanal Medication, Calcium Hydroxide (Ca(OH)2) Intracanal Medication
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Postoperative Pain, Flare Up, Symptom
Effect of a Herbal Intracanal Medication On Postoperative Pain And Flare up Incidence In Non Surgical Root Canal Retreatment
The primary objective of this randomized clinical trial is to evaluate and compare the effectiveness of two natural, herbal-based intracanal medications-Propolis and Green Tea Polyphenolics (EGCG)-against the conventional Calcium…
- Conditions
- Postoperative Pain, Flare Up, Symptom, Flare up
- Trial name
- NCT07578311
- Testing
- Calcium hydroxide, Propolis Extract, Green Tea Polyphenolics (EGCG)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Minia University
Hypersensitivity, Beta Lactam Adverse Reaction
Protocol of Reintroduction of Beta-lactams in Children at Low Risk of Anaphylaxis.
The purpose of this study is to establish the rationale for the practice of performing an oral reintroduction test without previous skin tests in children at low risk of IgE-mediated reaction or drug-induced toxidermia, and to…
- Trial name
- TRO-b-lact (NCT03553251)
- Where
- France
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
This Study Compares the Effects of Two Working Length Methods on Postoperative Pain in Single-rooted, Single-canal Teeth During Root Canal Retreatment
Evaluation of Postoperative Pain After Endodontic Retreatment Using Different Working Length Determination Methods: A Randomized Clinical Trial
The aim of this study is to compare the effects of two different working length determination methods on the incidence of postoperative pain in single-rooted, single-canal teeth undergoing root canal retreatment (RCR).
- Trial name
- NCT06732063
- Testing
- endodontic retreatment
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- öznur dişli
Obesity
Can Reverse Dieting Prevent Weight Regain After Weight Loss
Introduction: It is known that weight loss results in decreased Resting Energy Expenditure (REE), due to a decrease in lean body mass (LBM), but also due to metabolic adaptation, resulting in a higher energy efficiency…
- Trial name
- NCT03434431
- Testing
- Reverse dieting
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- George Mason University
Postoperative Pain, Root Canal Infection
Postoperative Pain in Single-visit and Multiple-visit Retreatment Cases
The purpose of this randomized clinical trial was to evaluate the incidence of postoperative pain after retreatment using different techniques. Patients whom need retreatment were included.
- Conditions
- Postoperative Pain, Root Canal Infection, Endodontic Disease
- Trial name
- NCT03042377
- Testing
- Single-Visit Retreatment, Multiple-Visit-"Calcium Hydroxide", Multiple-Visit-"Corticosteroid Paste"
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital