Clinical trials: Retrospective, open to volunteers
Stage IIIA Non-small Cell Lung Cancer
Pathological Response After Neoadjuvant Treatment on NSCLC
This is a non-interventional, observational, multicenter and retrospective study. Being limited to the collection of patient data already filled in the Tumor Thoracic Registry data base and the data from stage IIIA clinical…
- Trial name
- PLANET (NCT05167487)
- Testing
- Cisplatin, Carboplatin
- Where
- 17 sites in Spain
- Volunteers
- 150 people
- Sponsor
- Fundación GECP
Blau Syndrome
Effective Treatment of Jak1/3 Inhibitor in Blau Syndrome
To investigate the effectiveness of the JAK 1/3 inhibitor tofacitinib in treating Blau syndrome and explore the association between various clinical and genetic features and therapeutic responses within the cohort.
- Trial name
- inapplicable (NCT06688838)
- Testing
- Tofacitinib
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Tongji Hospital
Breast Cancer, HR+/HER2- Early-Stage
Predicting Recurrence in HR+/HER2- Early Breast Cancer
Hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2-) breast cancer constitutes approximately 70% of all breast cancer cases.
- Trial name
- NCT07484763
- Volunteers
- 500 people
- Sponsor
- Shengjing Hospital
Bacteremia Caused by Gram-Negative Bacteria, Bacterial Pneumonia
A Post-Marketing Study to Assess the Efficacy and Safety of Intravenous Polymyxin B and Colistin Methanesulfonate in Patients With Carbapenem-Resistant Gram-Negative Bacterial Infection
This is a retrospective, observational, post-marketing study to evaluate the clinical response, microbiological response, mortality, and safety of intravenous polymyxin B and colistin methanesulfonate in patients with…
- Trial name
- NCT06966284
- Where
- Taiwan
- Volunteers
- 480 people
- Sponsor
- TTY Biopharm
Lumbar Disc Herniation
Intradiscal Ozone/Oxygen Injection for Treatment of Contained Lumbar Disc Herniation
This study is retrospectively designed and aims to evaluate and summarize safety and performance data in eligible participants who have undergone Intradiscal ozone-oxygen injection for treatment of lumbar disc herniation with the…
- Trial name
- NCT07910422
- Testing
- Intradiscal ozone-oxygene injection
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Beam Research, Inc.
Gastric Cancer, Chemotherapy Effect
Predicting Gastric Cancer Response to Chemo With Multimodal AI Model
This study aims to develop a multimodal model combining radiomic and pathomic features to predict pathological complete response (pCR) in advanced gastric cancer patients undergoing neoadjuvant chemotherapy (NAC).
- Trial name
- NCT06451393
- Testing
- Neoadjuvant chemotherapy with radical tumor resection surgery
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Cervical Cancer, Locally Advanced Cervical Cancer
Study on Disease Characteristics and Treatment in Locally Advanced or Recurrent / Metastatic Cervical Cancer in Italy
Multicenter, Observational, Retrospective charts review. Observational study with descriptive purpose only. Retrospective data capture in consecutive patients diagnosed with CC who attended the Oncologic Clinics from Jan 2018 to…
- Conditions
- Cervical Cancer, Locally Advanced Cervical Cancer, Recurrent Cervical Cancer, Metastatic Cervical Cancer
- Trial name
- RETRACE (NCT06771193)
- Where
- 11 sites in Italy
- Volunteers
- 200 people
- Sponsor
- MSD Italia S.r.l.
Colorectal Cancer, Polyps
The Correlation of Postoperative Polyp Recurrence and Colorectal Cancer
Postoperative endoscopic polyp recurrence correlation of colorectal cancer: a retrospective cohort open-label study
- Trial name
- NCT07708415
- Testing
- Endoscopic polypectomy
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Gansu Provincial Hospital
MNGIE, Mitochondrial Neurogastrointestinal Encephalomyopathy (MNGIE)
MNGIE Natural History Study
The MNGIE Retrospective Natural History Study is a collaborative study between the University of Cambridge and the University of Bologna.
- Trial name
- NCT07627217
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Cambridge
H.Pylori Infection
Tegoprazan- Versus PPI-based H. Pylori Eradication
In 2015, vonoprazan, a potassium-competitive blocker (P-CAB), was launched in Japan and used as an alternative for proton pump inhibitors (PPIs) for eradicating Helicobacter pylori.
- Trial name
- NCT06682533
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Soonchunhyang University Hospital
Metastatic Castration-resistant Prostate Cancer (mCRPC)
PROLONG (PRostateOLaparibONcombinationGcc) Study
The study will generate regionally relevant data to inform clinical practice, support treatment guidelines, and potentially contribute to supportive evidence for health authority discussions or scientific publications.
- Trial name
- PROLONG (NCT07674121)
- Testing
- Olaparib and Abiraterone Combination
- Volunteers
- 75 people
- Sponsor
- AstraZeneca
Tibial Fracture
Assessment of the Verus Frame in Tibial Intramedullary Nailing
This prospective, single-arm Post-Market Clinical Follow-Up (PMCF) study, utilizing a registry-based control group, will assess the Verus frame's effectiveness in achieving precise tibial rotation and alignment during…
- Trial name
- NCT07362121
- Testing
- Verus frame to stabilize tibia
- Where
- Finland
- Volunteers
- 25 people
- Sponsor
- Hemitec Finland Oy
Colo-rectal Cancer
Early-Onset Colorectal Cancer: An Observational Retrospective and Prospective Multicenter Study
Observational, retrospective and prospective multicentric Italian study of patients diagnosed with colorectal cancer between age 18-40, aiming at underpinning the biology of vEO-CRC, including colibactin as well as a broader…
- Trial name
- HEBE (NCT06965335)
- Testing
- BIOLOGICAL STUDY aiming at describing clinicophatological features of EO-CRC vs SO-CRC
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Niguarda Hospital
Epiploic Appendagitis
Differentiating Right-sided Epiploic Appendagitis From Diverticulitis
This study will perform a retrospective analysis of adult patients who presented to the emergency department of National Taiwan University Hospital, Hsin-Chu and Yun-Lin Branches between January 2022 and December 2025 and were…
- Trial name
- NCT07794865
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Hepatocellular Carcinoma (HCC)
Biomarker Validation for Treatment Efficacy and Recurrence Prediction in Hepatocellular Carcinoma
Observational Model: Cohort Time Perspective: Other (prospective and retrospective data/sample collection) Primary Purpose: Other (biomarker validation for treatment response and recurrence prediction) Biospecimen Retention…
- Trial name
- NCT07840092
- Testing
- No investigational intervention. Participants receive standard clinical care. Clinical data, imaging/pathology information, and available biospecimens are collected for research.
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Alzheimer Disease (AD)
Generation of Synthetic [18F]FDG PET From Early-Phase Amyloid PET in Alzheimer's Disease
This study aims to test a new artificial intelligence (AI) method to create brain scan images without needing an extra scan. Currently, patients with memory problems often undergo two types of PET scans (Amyloid PET and FDG PET)…
- Trial name
- NCT07431255
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- IRCCS San Raffaele
Short Bowel Syndrome (SBS)
A Study of Teduglutide in Chinese Children and Teenagers With Short Bowel Syndrome
Short Bowel Syndrome (SBS) is a rare condition that happens when a large part of the bowel (also called intestine) is missing or has been removed because of illness or surgery.
- Trial name
- NCT07319832
- Testing
- No Intervention
- Where
- 4 sites in China
- Volunteers
- 12 people
- Sponsor
- Takeda
Cutaneous T-Cell Lymphoma/Mycosis Fungoides
Long-term Assessment of Chlormethine Gel in Mycosis Fungoides
The study aims to provide comprehensive insights into the long-term therapeutic outcomes, potential adverse effects, and overall patient experience with chlormethine gel, thereby informing clinical practice and guiding future…
- Trial name
- FIL_CLOR-CTCL (NCT07046663)
- Where
- 20 sites in Italy
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Fondazione Italiana Linfomi - ETS
Kidney Neoplasm, Nephrectomy
Evaluation of 'RUS NE' in Robot-Assisted Partial Nephrectomy: Efficacy, Safety, and Stability
This study is a retrospective and prospective comparative study evaluating the efficacy, safety, and stability of the surgical navigation system 'RUS NE' in robot-assisted partial nephrectomy.
- Conditions
- Kidney Neoplasm, Nephrectomy, Surgical Navigation Systems, Renal Mass
- Trial name
- HTK_002 (NCT06945640)
- Testing
- RUS NE
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Hutom Corp
Glaucoma
INTEGRAL Study: A Longitudinal Study of Surgeries and Lasers in Glaucoma
The aim of this study is to create a large-scale register of all glaucoma patients diagnosed, followed and treated in a large tertiary centre specialising in glaucoma, in order to analyse whether specific factors influence the…
- Trial name
- NCT06227299
- Where
- Switzerland
- Volunteers
- 5,000 people
- Sponsor
- Swiss Glaucoma Research Foundation