Clinical trials: RhA - Rheumatoid Arthritis
Osteoarthritis, Rheumatoid Arthritis
Total Knee Replacement With the ROCC Knee
The purpose of this study was to assess the results of a Total Knee prosthesis specifically intended to enhance functional performance , especially in terms of physical and sports activity.
- Trial name
- NCT02127619
- Testing
- Total knee replacement with the ROCC® knee prosthesis
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Bercovy, Michel, M.D.
Rheumatoid Arthritis
Study To Assess The Efficacy And Safety Of Pf-06651600 In Subjects With Rheumatoid Arthritis With An Inadequate Response To Methotrexate
This is an 8 week study to assess the efficacy and safety profile of PF-06651600 in seropositive subjects with rheumatoid arthritis with an inadequate response to methotrexate (up to approximately 50% of subjects may also have…
- Trial name
- NCT02969044
- Testing
- PF-06651600
- Where
- 30 sites in United States, Bulgaria and 7 more
- Volunteers
- 70 people
- Sponsor
- Pfizer
Rheumatoid Arthritis
Long-term Treatment Study of MRA for Rheumatoid Arthritis (RA) From Study MRA213JP
This is an open-label, extension, Phase III study to evaluate the long-term safety and efficacy of MRA in patients with RA who participated in Study MRA213JP.
- Trial name
- NCT00144534
- Testing
- MRA (Tocilizumab)
- Volunteers
- 115 people
- Sponsor
- Chugai Pharmaceutical
Effect of Manual Lymphatic Drainage on Upper Extremity Functionality in Rheumatoid Arthritis
Manual Lymphatic Drainage for Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a chronic, progressive, autoimmune disease characterized by inflammation of the synovial joints and tendon sheaths. As a result of synovitis, progressive damage occurs in cartilage, bone and joints.
- Trial name
- NCT05529537
- Testing
- manual lymphatic drainage, excersize
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Selcuk University
Rheumatoid Arthritis (RA)
A Study to Compare Efficacy, Pharmacokinetics, Safety and Immunogenicity of MB04 [Proposed Etanercept Biosimilar] to Enbrel® [EU-sourced] in Rheumatoid Arthritis
A study to compare efficacy, pharmacokinetics, safety and immunogenicity of MB04 [proposed etanercept biosimilar] to Enbrel® [EU-sourced] in rheumatoid arthritis
- Trial name
- NCT06596772
- Testing
- MB04 (proposed biosimilar to etanercept), Enbrel (etanercept)
- Where
- 60 sites in Bulgaria, Georgia and 4 more
- Volunteers
- 501 people
- Sponsor
- mAbxience Research S.L.
Rheumatoid Arthritis
Soluble Programmed Death 1 (sPD1) is a Diagnostic Biomarker of ILD in Patients With Rheumatoid Arthritis Disease
1. Evaluate the levels of serum (sPD1) in RA patients with ILD and those without. 2. Detect subclinical RA-ILD for early diagnosis and management of this devastating manifestation of RA
- Trial name
- NCT05105230
- Testing
- soluble programmed death 1biomarker
- Volunteers
- 66 people
- Sponsor
- Assiut University
Rheumatoid Arthritis
Drug-Drug Interaction Study of MRA in Patient With Rheumatoid Arthritis (RA)
This is an open-label, clinical pharmacology study to investigate drug-drug interaction in patients with RA.
- Trial name
- NCT00144560
- Testing
- MRA(Tocilizumab)
- Volunteers
- 31 people
- Sponsor
- Chugai Pharmaceutical
Osteoarthritis, Rheumatoid Arthritis
Outcomes Study of the TM Humeral Stem Used in Primary, Total or Hemi Shoulder Arthroplasty
The objectives of this study are to obtain survival and outcome data on the Trabecular Metal Humeral Stem when used in primary, total or hemi shoulder arthroplasty.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Arthritis, Ununited Humeral Head Fracture
- Trial name
- NCT01480453
- Testing
- Trabecular Metal Humeral Stem
- Where
- 3 sites in United States
- Volunteers
- 67 people
- Sponsor
- Zimmer Biomet
Rheumatoid Arthritis
A Single Dose Study of the CAM-3001 in Patients With Rheumatoid Arthritis
Investigate safety and tolerability of the escalating dose of CAM-3001 in patients.
- Trial name
- NCT00771420
- Testing
- CAM-3001
- Where
- Germany
- Volunteers
- 38 people
- Sponsor
- MedImmune Ltd
Training Leaflet, Training Workshop
Group Training and Quality of Life and Reduction of Pain in Rheumatoid Arthritis Patients
Abstract Background: It is documented that some patient education interventions, preferably with a behavioral component included, may improve pain, disability and moods Purpose of the study: the purpose of this study was to…
- Trial name
- NCT01998373
- Testing
- training leaflet and oral training
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Tehran University of Medical Sciences
Rheumatoid Arthritis
Extension Study of Tocilizumab Long Term Treatment of Moderate to Severe Rheumatoid Arthritis Patients
24 week open-labeled extension study to continue monitoring the same group of patients in the previous MRA230TW phase IIIb trial in order to evaluate the long term efficacy and safety of tocilizumab.
- Trial name
- NCT01347983
- Testing
- Tocilizumab+Methotrexate(MTX)
- Where
- 12 sites in Taiwan
- Volunteers
- 72 people
- Sponsor
- Chugai Pharma Taiwan
Rheumatoid Arthritis
Patient-Reported Efficacy of Subcutaneous (SC) Abatacept in Rheumatoid Arthritis (RA) - South Africa
Research question: what are the patterns of patient-reported changes in physical function among adult patients using SC abatacept with moderate to severe RA since commencement of the compassionate use program (CUP).
- Trial name
- NCT02598466
- Testing
- Abatacept
- Volunteers
- 69 people
- Sponsor
- Bristol-Myers Squibb
Rheumatoid Arthritis, Osteoarthritis
A Study to Assess the Long-term Performance of SmartSet® HV and SmartSet® GHV Bone Cements in Primary Total Hip Replacement
The purpose of this study is to monitor the performance of artificial hip joints implanted with two different bone cements, SmartSet® HV and SmartSet® GHV, in the treatment of patients with hip joint disease requiring a total hip…
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Post-traumatic Arthritis, Collagen Disorders
- Trial name
- NCT00872066
- Testing
- SmartSet® HV bone cement, SmartSet® GHV bone cement
- Where
- Slovakia
- Volunteers
- 243 people
- Sponsor
- DePuy International
Knee Pain, Chronic Osteoarthritis
ROSA Total Knee Investigational Testing Authorization Study
This is a prospective, single-center clinical study designed to facilitate the collection and evaluation of workflow efficiency, patient pain and function, and adverse event data.
- Conditions
- Knee Pain, Chronic Osteoarthritis, Avascular Necrosis of Femoral Condyle, Moderate Varus, Valgus or Flexion Deformities
- Trial name
- NCT03970629
- Testing
- PERSONA Total Knee
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Rheumatoid Arthritis, Kinesiotape
Kinesiotaping Applied to the Thumb in Rheumatoid Hand
Objective: It was aimed to evaluate the acute effect of Kinesiotape taping on pain, function, range of motion and grip strength parameters in patients with rheumatoid arthritis and hand involvement.
- Conditions
- Rheumatoid Arthritis, Kinesiotape, Hand Deformity
- Trial name
- NCT05515965
- Testing
- Kinesiotaping
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Istanbul Arel University
Arthritis, Rheumatoid
Evaluation of Pharmacokinetics and Safety of GSK3196165 in Combination With Methotrexate in Japanese Subjects With Rheumatoid Arthritis
This is a randomized, double-blind, parallel group, 3 dosage level, placebo-controlled, Phase 1/2 study designed to evaluate the pharmacokinetics, safety, tolerability, and efficacy of the monoclonal antibody GSK3196165, in…
- Trial name
- NCT03028467
- Testing
- GSK3196165 Dose 1, GSK3196165 Dose 2, GSK3196165 Dose 3
- Where
- 32 sites in Japan
- Volunteers
- 15 people
- Sponsor
- GlaxoSmithKline
Helicobacter Pylori Infection
H-pylori Infection With Disease Activity in Systemic Lupus Erythematosus and Rheumatoid Arthritis
To find the relation of Helicobacter pylori with disease activity in SLE and RA
- Trial name
- NCT06586567
- Testing
- Full history , clinical examination, assesment of disease activity ,Laboratory investigations ( CBC , ESR, CRP Serum creatinine and blood urea, Random plas
- Volunteers
- 150 people
- Sponsor
- Assiut University
Rheumatoid Arthritis, Predictive Value of Ultrasound in Early Rheumatoid Arthritis
The Predictive Value of Ultrasound in Early Rheumatoid Arthritis
Rheumatoid arthritis a chronic and progressive inflammatory disease characterized by synovial membrane inflammation, possibly leading to destruction of joints.
- Trial name
- EVA (NCT01752309)
- Where
- 7 sites in Netherlands
- Volunteers
- 150 people
- Sponsor
- Erasmus Medical Center
Arthritis, Rheumatoid
Long-term Safety and Efficacy of Sirukumab in Participants With RA Completing Studies CNTO136ARA3002 or CNTO136ARA3003
The purpose of this study is to evaluate the long-term safety and efficacy of CNTO 136 (sirukumab) in participants with rheumatoid arthritis (RA) who are unresponsive to treatment with modifying antirheumatic drugs (DMARDs) or…
- Trial name
- SIRROUND-LTE (NCT01856309)
- Testing
- Sirukumab 100 mg, Sirukumab 50 mg
- Where
- 197 sites in United States, Argentina and 27 more
- Volunteers
- 1,820 people
- Sponsor
- Janssen Research & Development, LLC
Arthritis, Rheumatoid
A Pilot Study of the Feasibility of Discontinuation of Adalimumab in Stable Rheumatoid Arthritis Patients in Clinical Remission
The purpose of this pilot study is to investigate the possibility of discontinuing adalimumab therapy in patients with rheumatoid arthritis who are in stable remission after treatment with adalimumab in combination with…
- Trial name
- ADMIRE (NCT00808509)
- Testing
- adalimumab, methotrexate
- Where
- 8 sites in Sweden
- Volunteers
- 33 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
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