Clinical trials: Rheumatic Disorder
Fibromyalgia
Influence of Exercise Type, Pain Mechanisms, and Biopsychosocial Contributions to Pain Relief in Those With Fibromyalgia
The purpose of this study is to investigate the influence different types of exercise, pain mechanisms, and biopsychosocial contributions on how people with and without fibromyalgia report pain.
- Trial name
- NCT03778385
- Testing
- Exercise
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Marquette University
Osteoarthritis
The Combined Use of PRP with Lipoaspirate And/or Bone Marrow Aspirate in Osteoarthritis
To demonstrate the efficacy of the combined use of platelet-rich plasma (PRP) with lipoaspirate and/or bone marrow aspirate in osteoarthritis of major joints, and to compare the outcomes achieved using three combinations: PRP…
- Trial name
- NCT03984461
- Testing
- Autologous cell therapy
- Where
- Canada
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Dr. Grant M. Pagdin
Fibromyalgia
Multicomponent Therapy With Telerehabilitation
In this prospective, randomized study, our aim was to evaluate the comprehensive multicomponent treatment of fibromyalgia women with telerehabilitation, including "patient education, special psychotherapy/psychosocial…
- Trial name
- NCT05250531
- Testing
- multicomponent therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Gout, Hyperuricemia
Renal PK Study of LC350189
This is a Phase 1, open-label, parallel-group, multiple-dose study designed to assess the effect of renal impairment on the PK and PD of LC350189.
- Trial name
- NCT04066712
- Testing
- LC350189 200 mg
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- LG Chem
Chronic Pancreatitis, Inflammatory Bowel Diseases
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect…
- Conditions
- Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis
- Trial name
- GREAT1 (NCT04306939)
- Testing
- venipuncture, Questionnaires, Additional Sample Collections
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Rheumatoid Arthritis
Rheumatoid Arthritis, Planned Behavıor Theory And Nurse Counselıng
Ensuring disease management begins with comprehensive education and drug therapy. Symptoms such as deformities, pain and fatigue, which are most common in rheumatoid arthritis patients, seriously affect the daily activities of…
- Trial name
- NCT05039372
- Testing
- TRAINING AND CONSULTANCY
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Healthy Participants, Rheumatoid Arthritis (RA) Prevention
Strategy to Prevent the Onset of Clinically-Apparent Rheumatoid Arthritis
The purpose of this study is to determine if hydroxychloroquine (HCQ) is safe and effective for the prevention of future onset of rheumatoid arthritis (RA) in individuals who have elevations of an autoantibody, anti-cyclic…
- Trial name
- StopRA (NCT02603146)
- Testing
- Hydroxychloroquine
- Where
- 14 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Knee Osteoarthritis
Risk Factor Involved in Knee Osteoarthritis (KOA)
Clinical study regarding the incidence and severity of knee osteoarthritis (KOA) in a certain area from South-Eastern Europe. Aim of the clinical study: to determine the KOA grade through X-Ray studies, to perform nuclear…
- Trial name
- NCT05749601
- Testing
- Influence of the metabolic syndrome (MetS) parameters on knee osteoarthritis (KOA) severity, the assesment of the reactive oxygen species and reactive nitrogen species in knee synovial fluid, The influence of patellofemoral morphology in the radiological severity of knee osteoarthritis, The influence of ROS from the synovial fluid on the severity of KOA
- Where
- Romania
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Iacob Czihac Emergency Military Clinical Hospital
Knee Osteoarthritis
Phase 1b Clinical Trial to Evaluate PEP and EUFLEXXA for Knee Osteoarthritis (KOA)
Evaluate the safety and exploratory efficacy of single intra-articular injections of PEP reconstituted with 0.9% Normal Saline at a low dose (one vial PEP) and high dose (two vials PEP), with and without EUFLEXXA, for the…
- Trial name
- NCT06463132
- Testing
- PEP/Euflexxa, PEP
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Rion Inc.
Rheumatoid Arthritis (RA)
National Cohort of Subjects at Risk of Developing Rheumatoid Arthritis
PROMESS 1 is a multicenter cohort interventional study aiming at analyzing the factors associated with the risk of developing clinical arthritis among exposures or combinations of exposures in patients at risk of rheumatoid…
- Trial name
- PROMESS_1 (NCT06876064)
- Testing
- Blood test, Urine test, stool collection
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Rheumatoid Arthritis
An Evaluation of the Optimal Dose of Tofacitinib Needed to Achieve Low Disease Activity (LDA) or Clinical Remission in Patients With Active Rheumatoid Arthritis (RA) as Measured From a Clinical and Structural Perspective
This study will evaluate the optimal dose of tofacitinib needed to achieve low disease activity (LDA) or clinical remission as measured by the CDAI score.
- Trial name
- NCT02566967
- Testing
- tofacitinib
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Norman B. Gaylis, MD
Osteoarthritis, RA
Surgical Tourniquets and Cerebral Emboli
BACKGROUND In 2012 76,497 primary total knee (TKR) replacements were performed in England, Wales and Northern Ireland . Traditionally TKR surgery is undertaken with the aid of a surgical tourniquet.
- Conditions
- Osteoarthritis, RA, Trauma
- Trial name
- NCT02240732
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Diabetes, Hypertension
Quality IQ Patient Simulation Physician Practice Measurement and Engagement
This study will test the quality of physician care decisions using a patient-simulation based measurement and feedback approach that combines multiple-choice care decisions with real-time, personalized scoring and feedback.
- Conditions
- Diabetes, Hypertension, Depression, Osteoarthritis
- Trial name
- Q-IQ (NCT03800901)
- Testing
- Continuing Medical Education, Quality IQ Patient Simulations
- Where
- United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Qure Healthcare, LLC
Osteo Arthritis Knee, Quadriceps Muscle Atrophy
Effect of Physical Therapy Modalities in Osteoarthritis
The purpose of this study was to find the most effective treatment out of both techniques; Dry needling and Kinesio Taping for treating knee osteoarthritis (OA) in terms of pain, strength, and balance
- Trial name
- NCT05089253
- Testing
- Dry Needling, Kinesio tapping
- Where
- India
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Majmaah University
RA, SLE
Vaccination in Inflammatory Rheumatic Disease (VACCIMIL). The Impact of Antirheumatic Treatment on Antibody Response
The overall objective of this project is to study the influence of modern anti-inflammatory treatments in established inflammatory rheumatic diseases (IRD) on immune response elicited by pneumococcal vaccination using 13-valent…
- Conditions
- RA, SLE, Vasculitis, Scleroderma
- Trial name
- Vaccimil (NCT02240888)
- Testing
- 0,5 mg Prevenar i.m., 0,5 mg seasonal influenza vaccine i.m.
- Where
- Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Region Skane
Rheumatoid Arthritis
The Effects of a 16-Week Individualized, Intensive Strength Training Program in Patients With Rheumatoid Arthritis
To assess the effects of a 16-week individualized, intensive strength training program in patients with rheumatoid arthritis. Primary and secondary outcomes include: strength and body composition, function, disease activity…
- Trial name
- NCT00327275
- Testing
- strength training
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Osteoporosis, Liver Steatosis
China Action on Spine and Hip Status
1. To determine the prevalences of osteoporotic fracture in elderly Chinese population. 2. To determine the prevalences of osteoporosis in elderly Chinese population using QCT BMD measurement. 3.
- Conditions
- Osteoporosis, Liver Steatosis, Metabolic Syndrome, Obesity
- Trial name
- CASH (NCT01758770)
- Where
- China
- Volunteers
- 3,457 people, healthy volunteers welcome
- Sponsor
- Beijing Jishuitan Hospital
Rheumatoid Arthritis
Investigation of Immunological and Pharmacological Factors for Response to Adalimumab in Rheumatoid Arthritis
Interventional study with minimal risks and constraints, prospective, mono-centric.
- Trial name
- PROMETHEE (NCT03110094)
- Testing
- Adalimumab, Healthy volunteers
- Where
- France
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Stress, Job, PTSD
The Sequestration of Holistic Stress Management Techniques for Adults
This remote study is intended to assist the population with access to cost-effective pastoral counseling for stress management in the workplace and every day life.
- Conditions
- Stress, Job, PTSD, Hypervigilance, Hyperthyroidism
- Trial name
- NCT06098755
- Testing
- Holistic Medicine (HM)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Goddess Zena I. Jones
Diet Interventions
The Triad of Nutrition, Intestinal Microbiota and Rheumatoid Arthritis (TASTY)
The main goal of this trial is to investigate whether a dietary intervention based on a typical Mediterranean Diet enriched with fermented foods (MedDiet+) can impact gut microbiota and RA-related outcomes.
- Trial name
- TASTY (NCT06758817)
- Testing
- MedDiet+ intervention, General dietary recommendations
- Where
- 2 sites in Portugal
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Lisbon Academic Medical Center - Centro Académico de Medicina de Lisboa
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