Clinical trials: Rheumatic Disorder
Idiopathic Juvenile Arthritis
Biomarkers in Idiopathic Juvenile Arthritis
Juvenile idiopathic arthritis (JIA) is the most common form of arthritis in children. The etiology is unknown. Several types of arthritis fall under the JIA heading.
- Trial name
- NCT02343770
- Testing
- blood sample for identifying biomarkers
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Osteoarthritis, Pain
A SAD Study to Evaluate the Safety, Tolerability and PK/PD of iN1011-N17 in Healthy Volunteers
A First-in-Human, Double-blind, Randomized, Placebo-controlled, Single Ascending Dose Study to Evaluate Safety, Tolerability, Pharmacokinetics/Pharmacodynamics of iN1011-N17 after Oral Administration in Healthy Volunteers.
- Conditions
- Osteoarthritis, Pain, Post Herpetic Neuralgia, Neuropathic Pain
- Trial name
- NCT05496205
- Testing
- iN1011-N17
- Where
- Australia
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- iN Therapeutics Co., Ltd.
Fibromyalgia, Social Media Addiction
Fibromyalgia and the Act of Scrolling Through Social Media.
In recent years, the widespread use of social media and digital platforms has led to the emergence of behavioural patterns such as doomscrolling, which involves the compulsive consumption of negative or distressing online…
- Trial name
- NCT07092462
- Where
- Turkey (Türkiye)
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Uşak University
Rheumatoid Arthritis, Healthy Control
Core Endurance, Finger Grip Strength, Fatigue, and Hand Function in Patients With Rheumatoid Arthritis
This study investigated the relationships between core endurance, finger grip strength, fatigue, and hand function in patients with rheumatoid arthritis.
- Trial name
- NCT07360496
- Where
- Turkey (Türkiye)
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Knee Osteoarthritis
Comparing Exparel & Ropivacaine for Pain Relief in Total Knee Arthroplasty
The purpose of this prospective study is to examine the effect of two local anesthetics used in adductor canal blocks, with relation to pain, analgesic consumption, mobility, and pain related interference with activities and…
- Trial name
- NCT02607579
- Testing
- Exparel, Ropivacaine
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Monmouth Medical Center
Knee Osteoarthritis (Knee OA)
Muscle Isometric Contraction for the Treatment of Knee Osteoarthritis
This study compares the effects of three different intensities of Muscle Isometric Contraction (MIC) on balance ability, proprioception, muscle strength, KOA symptoms, and inflammatory factors in synovial fluid among elderly…
- Trial name
- KOA (NCT06870656)
- Testing
- Low-intensity group, Medium-intensity group, High-intensity group
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chengdu Sport University
Knee Osteoarthritis
Persona MC vs Attune Total Knee Replacement Study
This study aims to compare clinical and functional outcomes of a cohort of patients that have undergone a medial congruent TKR to a similar cohort of patients that have undergone a conventional TKR and a cohort of control…
- Trial name
- PERTUNE (NCT03580772)
- Testing
- Persona TKR, Attune TKR
- Where
- United Kingdom
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Fibromyalgia
Generalized Hypersensitivity in Patients With Fibromyalgia Syndrome
Fibromyalgia (FM) is a chronic musculoskeletal pain disorder with unknown causes. Our previous studies showed abnormal sensations of second pain (wind-up), indicating central hypersensitivity as an important mechanism of FM.
- Trial name
- NCT04415866
- Testing
- Paced Auditory Serial Addition task (PASAT)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Florida
Knee Osteoarthritis
Effect of Different Mobilization Techniques With Common Use of Interferential Therapy in Patients With Knee OA
This study aimed to determine the effects of different manual mobilization techniques on pain, muscle strength, and functional limitations in individuals with knee osteoarthritis (Knee OA).
- Trial name
- NCT06025929
- Testing
- Maitland's mobilization technique, Mulligan's mobilization techniques, Interferential Therapy (IFT)
- Where
- Saudi Arabia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- King Saud University
Knee Pain, Chronic Osteoarthritis
ROSA Total Knee Investigational Testing Authorization Study
This is a prospective, single-center clinical study designed to facilitate the collection and evaluation of workflow efficiency, patient pain and function, and adverse event data.
- Conditions
- Knee Pain, Chronic Osteoarthritis, Avascular Necrosis of Femoral Condyle, Moderate Varus, Valgus or Flexion Deformities
- Trial name
- NCT03970629
- Testing
- PERSONA Total Knee
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Rheumatoid Arthritis
Effect of a High-fat Meal on the Pharmacokinetics of SHR0302 and Mass Balance Study in Healthy Subjects
The purpose of this open-label, randomized, two-period, two-treatment (single doses of 10 mg SHR0302 fasted or fed), crossover study was to evaluate the effect of a high-fat meal on the pharmacokinetics of SHR0302 and mass…
- Trial name
- NCT02892370
- Testing
- SHR0302
- Where
- China
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Juvenile Idiopathic Arthritis
Immersive Virtual Reality Exergaming Program in Adolescents Diagnosed With Juvenile Idiopathic Arthritis
The aim of the study is to investigate the effect of home-based exercise program versus personalized IVR exergame (Fit-XR) program on physical fitness, functional capacity and physical activity in adolescents with Juvenile…
- Trial name
- JiaFiT-XR (NCT06176846)
- Testing
- Immersive Virtual Reality Exergaming Program, Home-Based Exercise Program
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Rheumatoid Arthritis (RA)
Evaluation of Functional Disability in Rheumatoid Arthritis Patients
Rheumatoid arthritis (RA) is a chronic, systemic, autoimmune inflammatory disease that mainly affects the joints and periarticular soft tissues.
- Trial name
- NCT07801261
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sohag University
Rheumatoid Arthritis
A MEDiterranean Diet in Rheumatoid Arthritis
The MEDRA study is a 12-week randomised controlled trial that aims to assess effects of a Mediterranean dietary telehealth intervention compared to the Irish Healthy Eating guidelines on the physical function and quality of life…
- Trial name
- NCT04262505
- Testing
- Mediterranean Diet Group, Healthy Eating Group
- Where
- Ireland
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Arthroplasty, Osteoarthritis, Knee
The Effects of Prehabilitative Exercise on Functional Recovery Following Total Knee Arthroplasty
The primary aim of this study is to determine the effects of pre-surgery exercise known as Prehabilitation, on functional outcomes for patients following Total Knee Arthroplasty (TKA) surgery.
- Trial name
- NCT03227120
- Testing
- Prehabilitation exercise
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Osteoarthritis
Outcomes of Robotic Total Hip Arthroplasty
The objectives of this study are to evaluate the clinical value of robotic-assisted total hip arthroplasty with respect to acetabular cup implantation, and to document the long-term clinical outcome of patients with Total Hip…
- Trial name
- NCT01672320
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Osteoarthritis, Knee
An Intervention Study Evaluating the Effects of a Raspberry Leaf Extract in an Osteoarthritic Population.
A double-blind, randomized, placebo-controlled clinical study to evaluate the efficacy of raspberry extract to alleviate symptoms of osteoarthritis in the knee.
- Trial name
- NCT03703024
- Testing
- Raspberry Leaf Extract
- Where
- Ireland
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Atlantia Food Clinical Trials
Psoriatic Arthritis, Arthritis
99mTc-anti-TNF-alpha Scintigraphy in the Evaluation of Inflammatory Processes Activity
Rheumatoid and psoriatic arthritis patients benefit from anti-TNF-α therapy, once it is effective in reducing joint and skin manifestations in 60-70% of patients with inflammatory articular joint and skin diseases.
- Trial name
- NCT02134613
- Testing
- 99mTc-anti-TNF-alpha Scintigraphy
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Hepatic Steatosis and Fibrosis in Rheumatoid Arthritis Patients
Hepatic Steatosis and Fibrosis in Rheumatoid Arthritis Patients
studying the prevalence of hepatic steatosis and fibrosis in a large scale of patients with RA and healthy controls
- Trial name
- NCT05679648
- Testing
- ultrasonography
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Herpes Zoster
Safety and Tolerability of Herpes Zoster Vaccine Rheumatologic Patients
The reactivation of varicella zoster virus (VZV) (herpes zoster (HZ)) is of substantial public health concern. Updated ACR recommendations for RA treatment suggest that RA patients aged ≥ 50 years should be vaccinated before…
- Trial name
- NCT03016884
- Testing
- Zostavax vaccine
- Where
- 3 sites in Israel
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
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