Clinical trials: Rheumatic Disorder
Healthy
Pharmacokinetics And Tolerability Of Subcutaneous Administration Of PF 04236921 In Healthy Volunteers
This study will evaluate the safety, tolerability, and pharmacokinetics of PF-04236921 administered as a single subcutaneous dose in healthy volunteers.
- Trial name
- NCT01166555
- Testing
- PF-04236921
- Where
- Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Pfizer
Osteoarthritis, Knee, Osteoarthritis, Hip
Surgical Joint Registry MBJRF
The purpose of this study is to follow the patient's short term and long term clinical outcome after undergoing joint replacement surgery.
- Trial name
- MBJRFREG (NCT03484325)
- Where
- United States
- Volunteers
- 990 people, healthy volunteers welcome
- Sponsor
- Memorial Bone and Joint Research Foundation
Body Image, Rheumatoid Arthritis
Assessment of Body Image in Patients With Rheumatoid Arthritis
Investigate body image of patients with rheumatoid arthritis, correlating with self-esteem, function and quality of life.
- Trial name
- BIRA (NCT00832910)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Osteoarthritis, Osteoarthritis (OA) of the Knee
A Clinical Study Evaluating the Dermal Safety of Soluble Denosumab Microneedle Patches
The goal of this clinical trial is to evaluate the skin safety of a soluble denosumab microneedle patch in participants with osteoporosis and osteoarthritis.
- Conditions
- Osteoarthritis, Osteoarthritis (OA) of the Knee, Osteoporosis, Osteoporosis (Senile)
- Trial name
- CSEDSSDMP (NCT07085520)
- Testing
- Microneedle with 0.24mg Denosumab, Saline Microneedle Patch, Microneedle with 1.2mg Denosumab
- Where
- China
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Osteoarthritis, Gait Disorders, Neurologic
Effect of Flamingo Exercises on Balance
The aim of this study is to determine the effect of flamingo exercise on balance in patients with balance impairment due to senil osteoarthritis
- Trial name
- NCT03361449
- Testing
- Flamingo exercise, training with kinesthetic ability trainer
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ufuk University
Osteoarthritis
The PLE²NO Self-management and Exercise Program for Knee Osteoarthritis
The PLE²NO (in Portuguese Education and Exercise Free Program for osteoarthritis) is a self-management and exercise program specific for elderly with knee osteoarthritis (OA), with the goals of managing OA symptoms, improving…
- Trial name
- NCT02562833
- Testing
- Self-Management and exercise, Educational
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Technical University of Lisbon
Hip OA
Non-weight Bearing in Hip Joint With Accompanying Joint Pain Might Not Progress Radiographic OA
As we have previously reported, the primary cause of hip OA with accompanying joint pain might be bone alterations which can be microfracture.
- Trial name
- NCT02329093
- Testing
- To MRI-detecting bone signal changes in radiographic hip OA
- Where
- Japan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shinshu University
Osteoarthritis, Overweight and Obesity
Fit and Strong! Plus Comparative Effectiveness Trial
This randomized controlled trial is comparing outcomes of customary Fit and Strong!, to Fit and Strong! Plus, an enhanced version of the program that incorporates weight management.
- Trial name
- NCT03180008
- Testing
- Fit and Strong!, Fit and Strong! Plus
- Where
- United States
- Volunteers
- 413 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Irritable Bowel, Fibromyalgia
Psychiatric Disorders and Functional Somatic Disorders
The objectives of this study are: Firstly, to investigate the association between psychiatric disorders and functional somatic disorder (FSD).
- Conditions
- Irritable Bowel, Fibromyalgia, Chronic Fatigue Syndrome, Bodily Distress Syndrome
- Trial name
- NCT06006715
- Volunteers
- 7,493 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Osteoarthritis, Knee Joint, Capsicum
Efficacy Study on Symptomatic Control of Patient With Knee Osteoarthritis Between 0.0125% of Capsaicin to Placebo
The purpose of this study is to determine whether capsaicin gel is effective in treating mild to moderate degrees of osteoarthritis of the knee in the elderly patient compared with placebo gel.
- Trial name
- OAknee (NCT00471055)
- Testing
- 0.0125% Capsaicin gel "CAPSIKA gel"
- Where
- Thailand
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Knee Osteoarthritis
Serum COMP and MMP-3 in Knee Osteoarthritis
Knee osteoarthritis is a common degenerative joint disease characterized by pain, stiffness, and functional limitation, significantly affecting quality of life.
- Trial name
- KOACOMP (NCT07528872)
- Testing
- Observational Study
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Fibromyalgia, Physical Function
The Role of Resilience for Physical Functioning of Patients With Fibromyalgia Syndrome Using the 6-Min Walk Test
Fibromyalgia (FM) is a prevalent chronic pain disorder, characterized by widespread musculoskeletal pain and fatigue that is associated with significant functional limitations. Its mechanisms are only partially understood.
- Conditions
- Fibromyalgia, Physical Function, Six-minute Walk Test
- Trial name
- 6MWT (NCT07611539)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Florida
Rheumatic Heart Disease
Screening and Secondary Prevention Rheumatic Heart Disease Study
After basic clinical screening including history and physical, Point of care ultrasound will be performed to look at Mitral, Aortic and Tricuspid Valves for regurgitation or stenosis.
- Trial name
- S2-RHD (NCT05991219)
- Where
- Pakistan
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Cardiovascular Diseases, Pakistan
Fibromyalgia
A Brain Imaging Study of Tai Chi on Fibromyalgia
To accomplish our Specific Aims, we propose to conduct a two-session fMRI experiment in up to 30 patients with fibromyalgia (FM) and up to 30 healthy controls.
- Trial name
- NCT01857219
- Testing
- Tai chi
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Osteoarthritis, Knee
nCap Pain Relief Patch vs. Placebo
The purpose of this study is to determine whether use of the nCap Medical Nano-Capacitive pain relief patch reduces subject pain as measured by subject pain scores, WOMAC scores (pain, stiffness and physical function), global…
- Trial name
- NCT04753567
- Testing
- nCap pain relief patch
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- nCap Medical
Fibromyalgia, Whiplash
Diffuse Noxious Inhibitory Controls (DNIC): Nociceptive Modulation and Interaction With Neurocognitive Performance in Chronic Pain
Diffuse noxious inhibitory control In order to quantify central sensitization in chronic pain patients, the Diffuse Noxious Inhibitory Control (DNIC) model has been used frequently.
- Conditions
- Fibromyalgia, Whiplash, Chronic Pain
- Trial name
- NCT01172795
- Testing
- Relaxation session, Neurocognitive test battery
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Healthy Subjects, Osteoarthritis
Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Doses in Healthy
The purpose of this study is to evaluate the safety and tolerbility of ascending multiple oral doses of AGG-523 in healthy subjects and in subjects with osteoarthritis.
- Trial name
- NCT00380900
- Testing
- AGG-523
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Osteoporosis, Liver Steatosis
China Action on Spine and Hip Status
1. To determine the prevalences of osteoporotic fracture in elderly Chinese population. 2. To determine the prevalences of osteoporosis in elderly Chinese population using QCT BMD measurement. 3.
- Conditions
- Osteoporosis, Liver Steatosis, Metabolic Syndrome, Obesity
- Trial name
- CASH (NCT01758770)
- Where
- China
- Volunteers
- 3,457 people, healthy volunteers welcome
- Sponsor
- Beijing Jishuitan Hospital
Healthy
PK And Safety Study Of PF-04171327 In Healthy Japanese And Western Subjects In Fasting And Fed Conditions
This Phase 1 study is the first clinical trial in Japanese subjects. This study is designed to evaluate the single- and multiple-dose pharmacokinetics, safety and tolerability of PF-04171327 oral tablet in healthy adult Japanese…
- Trial name
- NCT01362673
- Testing
- PF-04171327
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Pfizer
Osteoarthritis, Avascular Necrosis
Aequalis Pyrocarbon IDE; Replacing the Humeral Head in Hemi-Arthroplasty
The purpose of this study is to demonstrate safety and effectiveness of the Aequalis Pyrocarbon Humeral Head in hemiarthroplasty at 24 months.
- Conditions
- Osteoarthritis, Avascular Necrosis, Traumatic Arthritis
- Trial name
- PYC (NCT02525783)
- Testing
- Aequalis Pyrocarbon Humeral Head
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Stryker Trauma and Extremities
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.