Clinical trials: Rheumatoid Arthritis, completed
Rheumatoid Arthritis
Kineret in the Treatment of Rheumatoid Arthritis
Objective of the study is to gain knowledge about the administration of Kineret in patients with rheumatoid arthritis in the daily routine treatment and not in controlled trials.
- Trial name
- NCT02915094
- Testing
- Anakinra
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Swedish Orphan Biovitrum
Rheumatoid Arthritis, Inflammatory Arthritis
Safety and Effectiveness of Live Zoster Vaccine in Anti-Tumor Necrosis Factor (TNF) Users (VERVE Trial)
The VaricElla zosteR VaccinE (VERVE) trial evaluates the safety and effectiveness of the Herpes zoster (HZ) vaccine for shingles, Zostavax, in patients over 50 years old with arthritis and other diseases who are using anti-tumor…
- Conditions
- Rheumatoid Arthritis, Inflammatory Arthritis, Arthritis, Psoriatic Arthritis
- Trial name
- NCT02538341
- Testing
- Herpes Zoster (HZ) Vaccine
- Where
- 34 sites in United States
- Volunteers
- 617 people
- Sponsor
- University of Alabama at Birmingham
Rheumatoid Arthritis
Evaluate the Safety, Tolerability, Pharmacokinetics,and Clinical Activity of FB704A
The cause of Rheumatoid Arthritis (RA) is not fully understood. However, one of the substances secreted by certain cells in the body, interleukin-6 (IL-6), is believed to play a major role in chronic inflammation that is typical…
- Trial name
- NCT03890302
- Testing
- FB704A
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Fountain Biopharma Inc.
Rheumatoid Arthritis
The Effect of Adalimumab (Humira) on Vascular Abnormalities in Rheumatoid Arthritis. A Pilot Study.
The purpose of this study is to determine whether anti-inflammatory treatment with adalimumab (Humira) reduces endothelial activation in blood vessels in patients with active rheumatoid arthritis.
- Trial name
- NCT01270087
- Testing
- Adalimumab
- Where
- Sweden
- Volunteers
- 14 people
- Sponsor
- Skane University Hospital
Rheumatoid Arthritis
A Prospective Observational Study of Tocilizumab (RoActemra/Actemra) in Participants With Rheumatoid Arthritis
This prospective observational study will investigate the effect of tocilizumab on fatigue in participants with moderate to severe rheumatoid arthritis who have an inadequate response to disease-modifying antirheumatic drugs or…
- Trial name
- NCT01462162
- Testing
- Tocilizumab
- Where
- 16 sites in Spain
- Volunteers
- 122 people
- Sponsor
- Hoffmann-La Roche
Rheumatoid Arthritis
Study Evaluating Long-Term Safety Of ATN-103 In Subjects With Rheumatoid Arthritis
This open-label extension study will allow subjects who have completed either the 3242K1-2000-WW or 3242K1-2001-JA study to receive up to an additional 48 weeks of ATN-103 treatment and will provide data on the long-term safety…
- Trial name
- NCT01063803
- Testing
- ATN-103
- Where
- 67 sites in United States, Canada and 6 more
- Volunteers
- 266 people
- Sponsor
- Ablynx, a Sanofi company
Dry Eye Syndromes, Sjögren Syndrome
A Randomized, Parallel-Group Comparison Study of Topical Corticosteroids in Dry Eye Patients With Sjögren Syndrome
The purpose of this study is to evaluate the effectiveness of fluorometholone combined with sodium hyaluronate eye drops in the treatment of Sjögren syndrome.
- Trial name
- NCT02011776
- Where
- China
- Volunteers
- 35 people
- Sponsor
- Santen Pharmaceutical(China) Co.,LTD
Musculoskeletal Pain, Rheumatic Pain
A Clinical Study to Assess the Safety and Effectiveness of Dharasana Lep in Patients With Mild to Moderate Muscular, Joint, or Rheumatic Pain
A Prospective, Open-Label, Single-Centre Interventional Study to Evaluate the Efficacy and Safety of Dharasana Lep in Patients with Mild to Moderate Musculoskeletal Pain and Rheumatoid Arthritis.
- Trial name
- NCT07085780
- Testing
- LEP
- Where
- India
- Volunteers
- 35 people
- Sponsor
- NovoBliss Research Pvt Ltd
Periodontitis, Rheumatoid Arthritis
Therapeutic Management of Periodontitis and Clinical Manifestations of Rheumatoid Arthritis
Although RA pathomechanisms remains incompletely understood, periodontitis and RA share pathogenic features : genetic and environmental influences, chronic inflammatory disease, immunoregulatory imbalance, bacterial factors…
- Trial name
- ESPERA (NCT02779179)
- Testing
- Periodontal treatment
- Where
- 2 sites in France
- Volunteers
- 22 people
- Sponsor
- University Hospital, Toulouse
Inflammatory Bowel Disease
Analysis of Birth Outcomes of Swedish, Danish and Finnish Women Exposed to Remicade With Inflammatory Bowel Disease, Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, and Psoriasis
The purpose of this study is collection and analysis of information pertaining to pregnancy outcomes in women exposed to infliximab during pregnancy, relative to the background risk in similar but non-biologic exposed patients…
- Trial name
- NCT00658827
- Testing
- No intervention
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Janssen Biotech, Inc.
Rheumatoid Arthritis
Efficacy Confirmation Trial of CDP870 Without Coadministration of Methotrexate (MTX) in Japanese Rheumatoid Arthritis (RA)
The objectives of this study are to verify the superiority in efficacy (American College of Rheumatology 20%: ACR20) and investigate the pharmacokinetics and safety of CDP870 versus placebo without coadministration of MTX in…
- Trial name
- NCT00791921
- Testing
- CDP870
- Where
- 7 sites in Japan
- Volunteers
- 230 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Rheumatoid Arthritis
A Study to Evaluate Tocilizumab Treatment in a Real-Life Setting
This observational, multi-center study will evaluate the treatment regimen, treatment responses and safety of tocilizumab therapy in a routine clinical practice in participants with moderate to severe rheumatoid arthritis (RA).
- Trial name
- NCT01664104
- Testing
- Tocilizumab
- Where
- 24 sites in Italy
- Volunteers
- 151 people
- Sponsor
- Hoffmann-La Roche
Active Rheumatoid Arthritis
Study Evaluating The Efficacy And Safety Of SBI-087 In Seropositive Subjects With Active Rheumatoid Arthritis
This study is designed to evaluate the safety and efficacy of a dose and dosage regimen of SBI-087 in seropositive patients with active Rheumatoid Arthritis, who are on a stable dose of methotrexate.
- Trial name
- NCT01008852
- Testing
- SBI-087
- Where
- 55 sites in United States, Argentina and 8 more
- Volunteers
- 210 people
- Sponsor
- Pfizer
Rheumatoid Arthritis, Osteoarthritis
Patient Education in Rheumatoid Arthritis and Osteoarthritis
This project will evaluate the effectiveness and general usefulness of two arthritis patient education programs. The first, the Arthritis Self-Management Program, is a 6-week, community-based program taught in small groups by…
- Trial name
- NCT00000414
- Testing
- Arthritis Self-Management Program, SMART Program
- Where
- 5 sites in United States, Canada
- Volunteers
- 1,200 people
- Sponsor
- Stanford University
Ulcer
Efficacy and Safety Study of HZT-501 in Subjects Requiring Nonsteroidal Anti-Inflammatory Drug (NSAID) Treatment
The purpose of this study is to evaluate whether HZT-501 is effective in reducing the rate of development of ibuprofen-associated ulcers in patients who require long-term daily use of ibuprofen.
- Trial name
- NCT00450216
- Testing
- Ibuprofen/famotidine, Ibuprofen
- Volunteers
- 906 people
- Sponsor
- Amgen
Rheumatoid Arthritis
Proof-of-Concept Study With BMS-817399 to Treat Moderate to Severe Rheumatoid Arthritis
The purpose of this study is to assess whether BMS-817399 in combination with Methotrexate is effective in treating moderate to severe rheumatoid arthritis.
- Trial name
- RA (NCT01404585)
- Testing
- BMS-817399
- Where
- 29 sites in United States, Argentina and 5 more
- Volunteers
- 123 people
- Sponsor
- Bristol-Myers Squibb
Keratoconjunctivitis Sicca, Dry Eye Syndromes
Differential Diagnosis of Sjögren's Versus Non-Sjögren's Dry Eye
To investigate and compare the burden of dry eye in Sjögren's syndrome dry eye vs non-Sjögren's syndrome dry eye, as well as investigate the diagnostic potential of tear film mucins and various inflammatory cytokines evaluated by…
- Conditions
- Keratoconjunctivitis Sicca, Dry Eye Syndromes, Ocular Surface Disease, Sjogren's Syndrome
- Trial name
- NCT04493658
- Testing
- Questionnaires, Tear fluid sampling, Impression Cytology
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Rheumatoid Arthritis
The Effects of Nutritional on Disease Activity and Functional Status in RA
Rheumatoid arthritis (RA) is a chronic, autoimmune, systemic, inflammatory disease. RA is a chronic inflammatory disease in which many patients cannot achieve remission despite current pharmacological treatments.
- Trial name
- NCT05227885
- Testing
- questionnaire form
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Balikesir University
Rheumatoid Arthritis
A Study Comparing Upadacitinib (ABT-494) to Placebo in Adults With Rheumatoid Arthritis on a Stable Dose of Conventional Synthetic Disease-Modifying Antirheumatic Drugs (csDMARDs) Who Have an Inadequate Response to csDMARDs Alone
The primary objectives of this study are to compare the efficacy, safety, and tolerability of upadacitinib 30 mg once daily (QD) and 15 mg QD versus placebo for the treatment of signs and symptoms of adults with moderately to…
- Trial name
- SELECT-NEXT (NCT02675426)
- Testing
- Upadacitinib
- Where
- 167 sites in United States, Argentina and 36 more
- Volunteers
- 661 people
- Sponsor
- AbbVie
Rheumatoid Arthritis
Efficacy of Chinese Herbal Medicine Qing Re Huo Xue in Patients With Rheumatoid Arthritis
This study is a multicenter, randomized, double-blinded, placebo-controlled trial with two parallel arms. The aim of the study is to evaluate whether Chinese herbal medicine Qing Re Huo Xue (QRHX) combined with methotrexate (MTX)…
- Trial name
- NCT04170504
- Testing
- Qing Re Huo Xue (QRHX) granule, Methotrexate
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
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