Clinical trials: Rheumatoid Arthritis, completed
Sjögren's Syndrome
A Clinical Trial to Evaluate the Safety and Efficacy of Traditional Chinese Medicine in Sjögren's Syndrome.
To investigate the efficacy and safety of traditional Chinese medicine in patients with Sjogren's syndrome.
- Trial name
- NCT04111341
- Testing
- TCM (Gan-Lu-Yin)GLY
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Chung Shan Medical University
Rheumatoid Arthritis
Safety and Efficacy Vagal Nerve Stimulation in Patients With Rheumatoid Arthritis
This is a 12 week open label pilot study to determine the efficacy and safety of a surgically implanted, electrically active vagal nerve stimulation device in patients with active rheumatoid arthritis.
- Trial name
- NCT01552941
- Testing
- Cyberonics VNS System
- Where
- 4 sites in Bosnia and Herzegovina, Croatia and 1 more
- Volunteers
- 18 people
- Sponsor
- SetPoint Medical Corporation
Axial and Peripheral Spondyloarthritis, Rheumatoid Arthritis
Scintigraphic Detection of the Biodistribution of Tumor Necrosis Factor With a Radiolabeled Anti-TNFα in Patients With Active Rheumatoid Arthritis and Active Axial and Peripheral Spondyloarthritis
In this open-label monocentric explorative pilot trial the objective is to show the biodistribution of TNFα by administration of radiolabeled anti-TNFα in patients with active rheumatoid arthritis and spondylarthropathy.
- Trial name
- SCINTRA (NCT01590966)
- Testing
- administration of Cimzia®, Immunoscintigraphy with radiolabeled Cimzia®.
- Where
- Belgium
- Volunteers
- 41 people
- Sponsor
- University Hospital, Ghent
Sjogren's Syndrome, Vitamin D Deficiency
Corneal Nerve Structure in Sjogren's
Patients who are suspected of or diagnosed with Sjogren's disease will be evaluated for ocular symptoms and corneal nerve morphology.
- Trial name
- NCT03203382
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Pennsylvania
Psoriasis Circinata, Psoriatic Arthritis
Clinical and Dermoscopic Comparison of Rheumatoid Arthritis, Ankylosing Spondylitis and Psoriasis Patients' Nails
This study evaluates the fingernail findings of the rheumatoid arthritis, spondylopathy and psoriatic arthritis patient groups with the fingernails of psoriasis patients clinically and dermatoscopically and investigates the…
- Conditions
- Psoriasis Circinata, Psoriatic Arthritis, Rheumatoid Arthritis, Spondylarthropathies
- Trial name
- NCT04709354
- Testing
- Dermoscopic examination
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Knee Pain, Chronic Osteoarthritis
ROSA Robot Used in Total Knee Replacement Post Market Study
This is a prospective, multicenter clinical study designed to facilitate the collection and evaluation of workflow efficiency, patient pain and function, and adverse event data.
- Conditions
- Knee Pain, Chronic Osteoarthritis, Avascular Necrosis of the Femoral Condyle, Moderate Varus, Valgus or Flexion Deformities
- Trial name
- NCT03969654
- Testing
- PERSONA Total Knee, Vanguard Total Knee, NexGen Total Knee
- Where
- 5 sites in United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Rheumatoid Arthritis
A Randomized, Placebo-Controlled, Double-Blind, Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BMS-986104 in Healthy Male Subjects
The primary objective in this study is to assess if single doses of BMS-986104 that are safe, tolerable, and result in sufficient lymphopenia (50% to 70% reduction in absolute lymphocyte count) can be achieved without bradycardia…
- Trial name
- NCT02211469
- Testing
- BMS-986104
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Rheumatoid Arthritis
Pharmacokinetic and Safety Study With Adalimumab in Chinese Subjects With Mild Rheumatoid Arthritis
Pharmacokinetic and Safety Study with Adalimumab in Chinese Subjects with Mild Rheumatoid Arthritis
- Trial name
- NCT00650156
- Testing
- adalimumab
- Where
- China
- Volunteers
- 24 people
- Sponsor
- AbbVie
Rheumatoid Arthritis, Psoriatic Arthritis
Impact of Literacy Level on Patient Education and Health Among People With Arthritis
People with poor literacy may have worse health and less knowledge about how to manage their disease than patients at high reading levels.
- Conditions
- Rheumatoid Arthritis, Psoriatic Arthritis, Polyarthritis
- Trial name
- NCT00023205
- Testing
- 11th grade reading level arthritis materials, Interactive in-person arthritis education
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Brigham and Women's Hospital
Dry Mouth Associated With Sjogren's Syndrome, Xerostomia
A Safety and Efficacy Study of 552-02 in Subjects With Dry Mouth Associated With Sjogren's Syndrome
This clinical study is to determine whether daily administration of a formulation of 552-02 improves the dry mouth condition in subjects with primary Sjögren's syndrome.
- Trial name
- NCT00852839
- Testing
- 552-02
- Where
- 15 sites in United States
- Volunteers
- 140 people
- Sponsor
- Parion Sciences
Rheumatoid Arthritis, Psoriatic Arthritis
Assessment of Tender & Swollen Joints Count Score Performed by a Rheumatologist And Rheumatology Nurses in Patients With RA and PsA.
This study will establish a comparison in follow-up care of 100 patients between Health Care Practitioners, more specifically the rheumatologist and a trained nurse.
- Trial name
- APRAN (NCT02556034)
- Testing
- Disease evaluation.
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Isabelle Fortin
Rheumatoid Arthritis
N-3 PUFA and Rheumatoid Arthritis in Korea
The purpose of this study is to see if supplementation of n-3 polyunsaturated fatty acid (PUFA) can be beneficial for the patients with rheumatoid arthritis.
- Trial name
- NCT01618019
- Testing
- Omega-3 fatty acid
- Where
- South Korea
- Volunteers
- 109 people
- Sponsor
- Hanyang University
Rheumatoid Arthritis, Diabetes
Effects of a Multi-Faceted Psychiatric Intervention Targeted at the Complex Medically Ill: a Randomized Controlled Trial
Background: somatic patients with psychiatric co-morbidities are a major challenge for the health care system. This study evaluated a psychiatric intervention targeted at the complex medically ill identified by means of the…
- Trial name
- NCT00385528
- Testing
- Multi-faceted psychiatric intervention
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- University of Lausanne Hospitals
Secondary (AA) Amyloidosis, Rheumatoid Arthritis
Study of the Safety and Efficacy of NC-503 in Secondary (AA) Amyloidosis
The main objective of this study is to evaluate the safety and efficacy of NC-503 compared to placebo in patients with secondary (AA) amyloidosis using a composite assessment of clinical improvement/worsening of both renal and…
- Conditions
- Secondary (AA) Amyloidosis, Rheumatoid Arthritis, Nephrotic Syndrome, Familial Mediterranean Syndrome
- Trial name
- NCT00035334
- Testing
- NC-503 (Anti-amyloidotic (AA) Agent)
- Where
- 26 sites in United States, Finland and 10 more
- Volunteers
- 150 people
- Sponsor
- Bellus Health Inc. - a GSK company
Rheumatoid Arthritis, Arthritis
Humira in Rheumatoid Arthritis - Do Bone Erosions Heal?
Studies on tumor necrosis factor alpha antagonist (anti-TNF) therapy in rheumatoid arthritis (RA) patients have found that erosive damage may "heal" in some RA patients treated with anti-TNF.
- Conditions
- Rheumatoid Arthritis, Arthritis, Joint Diseases
- Trial name
- HURRAH (NCT00696059)
- Testing
- Adalimumab (Humira)
- Where
- 5 sites in Denmark
- Volunteers
- 52 people
- Sponsor
- Hvidovre University Hospital
Rheumatoid Arthritis
Study of the Optimal Protocol for Methotrexate and Adalimumab Combination Therapy in Early Rheumatoid Arthritis
This study compared the safety and efficacy of combination therapy with adalimumab plus methotrexate (MTX) to that of MTX monotherapy (i.e., placebo plus MTX) in subjects with early rheumatoid arthritis (RA).
- Trial name
- OPTIMA (NCT00420927)
- Testing
- adalimumab, methotrexate
- Where
- 170 sites in United States, Argentina and 19 more
- Volunteers
- 1,032 people
- Sponsor
- Abbott
Rheumatoid Arthritis
VACcination In Methotrexate Treated Rheumatoid Arthritis Patients
To estimate the rate of immunological answer 1 month after antipneumococcal vaccination by the conjugated vaccine Prevenar13 ® in patients suffered from rheumatoid polyarthritis and who begin a treatement by methotrexate either…
- Trial name
- VACIMRA (NCT01942174)
- Testing
- Prevenar 13, Pneumo23 / Pneumovax, Methotrexate - Immediate
- Where
- 21 sites in France, Monaco
- Volunteers
- 276 people
- Sponsor
- University Hospital, Montpellier
Rheumatoid Arthritis
Biochemical Role of Matrix Metalloproteinase -9 in Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a systemic autoimmune pathology associated with a chronic inflammatory process, which can damage both joints and extra-articular organs, including the heart, kidney, lung, digestive system, eye, skin…
- Trial name
- NCT06494813
- Testing
- conventional pcr
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Rheumatoid Arthritis
Efficacy and Safety of Adalimumab in Patients With Rheumatoid Arthritis in Routine Clinical Practice
Observation of safety, tolerability and effectiveness of adalimumab (Humira) therapy in a large patient collective under everyday clinical conditions over 2 years.
- Trial name
- NCT01077258
- Where
- 303 sites in Germany
- Volunteers
- 4,208 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Juvenile Rheumatoid Arthritis
Safety and Efficacy of Etanercept (Recombinant Human Tumor Necrosis Factor Receptor Fusion Protein [TNFR:Fc]) in Children With Juvenile Rheumatoid Arthritis (JRA)
The primary objective of this study was to determine the efficacy of etanercept in children with polyarticular course JRA.
- Trial name
- NCT03780959
- Testing
- Etanercept
- Volunteers
- 69 people
- Sponsor
- Amgen
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