Clinical trials: Rhinitis Allergic
Seasonal Allergic Rhinitis
Intranasal Steroids and the Nasal Ocular Response
Eye symptoms of tearing, redness and itch frequently occur in patients with allergic rhinitis or hayfever. The purpose of this study is to learn whether placing allergen (the substance that causes allergies) in the nose several…
- Trial name
- NCT00473915
- Testing
- fluticasone furoate
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Pollen Allergy
Comparison of the Efficacy and the Safety of Different Schedules of Administration of Sub-lingual Immunotherapy
The dose and the mode of administration of sublingual therapy remain open questions to determine the efficacy and safety of this desensitization therapy, the main purpose of this study is to evaluate if different routes of…
- Trial name
- NCT01500642
- Testing
- Slit One, Slit One ragweed
- Where
- Italy
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- ASST Fatebenefratelli Sacco
Sleep Apnea, Allergic Rhinitis
Impact of Pollution on Allergic Rhinitis and Sleep Quality: the POLLAR Study
It has been demonstrated that allergic rhinitis (AR) reduces sleep quality by some components such as nasal obstruction. Pollution and allergen exposure worsening AR, sleep quality is deteriorated.
- Conditions
- Sleep Apnea, Allergic Rhinitis, Allergic Asthma, Pollution Exposure
- Trial name
- POLLAR (NCT03776773)
- Testing
- Pollution exposure
- Where
- France
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Anaphylaxis
Bioavailability of Nasal Epinephrine
A Study to Compare the Bioavailability of Epinephrine following a Single Nasal Dose of FMXIN002 Microspheres Powder with Epinephrine 0.3 mg Intramuscular Injection in Adult Subjects with Seasonal Allergic Rhinitis with and…
- Trial name
- NCT04696822
- Testing
- Epinephrine Nasal Product, 1.6 mg, Epinephrine nasal product, 1.6 mg + allergen, Epinephrine Injection 0.3 mg
- Where
- Israel
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Nasus Pharma
Adenoid Hypertrophy, Allergy
Periostin Levels in Children With Adenoid Hypertrophy
This prospective observational study evaluated serum and tissue periostin levels in children with adenoid hypertrophy. Children with grade 3-4 adenoid hypertrophy who were scheduled for adenoidectomy were compared with children…
- Conditions
- Adenoid Hypertrophy, Allergy, Allergic Rhinitis
- Trial name
- NCT04152746
- Testing
- Periostin level
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Allergic Rhinitis, Rhinitis, Allergic, Seasonal
A Phase II Study Evaluating Intranasal GSK256066 and Azelastine Hydrochloride in Subjects With Seasonal Allergic Rhinitis
This study is an 8 day, randomised, double blind, 2-way crossover trial of repeat doses of intranasal GSK256066 and azelastine hydrochloride in the Vienna Challenge Chamber in subjects with seasonal allergic rhinitis (SAR).
- Trial name
- NCT00612118
- Testing
- GSK256066, azelastine hydrochloride
- Where
- Austria
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Allergic Asthma, Bronchial Inflammation
Fish Oil and Asthma in House Dust Mite Allergy
Native populations consuming high amounts of fish suffer less from allergic diseases. The purpose of this study is to determine whether polyunsaturated fatty acids (fish oil) might have a disease modifying influence on asthmatics…
- Conditions
- Allergic Asthma, Bronchial Inflammation, House Dust Mite Allergy
- Trial name
- NCT00380926
- Testing
- polyunsatturated fatty acids (fish oil)
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Rhinitis, Allergic, Perennial
Single Dosing Clinical Trial of HL151
The purpose of this study is to assess the pharmacokinetic characteristics of bepotastine after single oral administration of TALION tab, a IR formulation of bepotastine as reference drug and HL151, a SR formulation of…
- Trial name
- NCT02682745
- Testing
- HL151, TALION tab.
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hanlim Pharm. Co., Ltd.
Nonallergic Irritant Rhinitis
Intranasal Capsaicin Treatment for Non-Allergic Irritant Rhinitis
The proposed study seeks to investigate the effect of intranasal capsaicin treatment in patient with Non-allergic irritant rhinitis (NAIR), as well as evaluate optical rhinometry (ORM) as a means to quantify symptomatic…
- Trial name
- NCT02493257
- Testing
- Capsaicin
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Asthma With Allergic Rhinitis
Tezepelumab in Allergic Rhinitis and Asthma Study (TEZARS)
The goal of this clinical trial is to learn about how well tezepelumab (pronounced TEZ e PEL ue mab), a Health Canada-approved drug for severe asthma, works in participants with coexisting allergic asthma and allergic rhinitis…
- Trial name
- TEZARS (NCT06189742)
- Testing
- Tezepelumab
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Dr. Anne Ellis
Birch Pollen Allergy
Study of DM-101PX in Adults With Birch Pollen Allergy
Randomized, double-blind placebo-controlled phase 2 trial with the aim to investigate safety and efficacy of DM-101-PX in reducing allergic symptoms provoked by nasal allergen challenge in birch pollen allergic adults.
- Trial name
- BASIT (NCT07254871)
- Testing
- DM-101PX
- Where
- Canada
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Desentum Oy
Food Hypersensitivity, Asthma in Children
Toxicity of Micro and Nano Plastics Combined With Environmental Contaminants on the Risk of Allergic Disease
Single-center, cross-sectional, longitudinal, observational, population based cohort study with stratified sample (by age group, gender, and residential area).
- Conditions
- Food Hypersensitivity, Asthma in Children, Rhinitis, Allergic, Dermatitis, Atopic
- Trial name
- Imptox (NCT05177744)
- Where
- Croatia
- Volunteers
- 1,156 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Srebrnjak
Allergic Rhinitis
Grass Pollen Allergen Immunotherapy Tablet (AIT) Time Course Study
About 45 million people in Europe have allergic rhinitis (hay fever) - inflammation of the nasal passages causing sneezing, runny nose, nasal congestion, itching and tearing of the eyes.
- Trial name
- Pollen+ (NCT02005627)
- Testing
- Grazax
- Where
- United Kingdom
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Asthma, Allergic Rhinitis
Study on the Influence of Climatic and Environmental Factors on Respiratory Diseases in Sanya, Hainan Province, China.
To investigate the Influence of Climatic and Environmental Factors on Respiratory or Allergic Diseases in Sanya.
- Conditions
- Asthma, Allergic Rhinitis, Chronic Obstructive Pulmonary Disease(COPD), Atopic Dermatitis
- Trial name
- NCT05330637
- Testing
- Climate and environment in Sanya
- Where
- China
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Allergic Asthma
A Study of Genolair in Two Dosage Forms (Solution and Lyophilisate) and Xolair® in Healthy Volunteers
This is a phase I an open-label randomized comparative study in parallel groups of pharmacokinetics, pharmacodynamics, immunogenicity, and safety of Genolair in two dosage forms (solution for subcutaneous administration and…
- Trial name
- NCT06494345
- Testing
- Genolair, solution for subcutaneous administration, 150 mg, Genolair, lyophilisate for the preparation of solution for subcutaneous administration, Xolair®, solution for subcutaneous administration, 150 mg
- Where
- Russia
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- AO GENERIUM
Asthma and Rhinitis
A Study to Investigate the Safety and Pharmacodynamics of Repeat Intranasal Administration of the TLR7 Agonist GSK2245035 in Subjects With Respiratory Allergies
GSK2245035 is a highly selective Toll-like receptor 7 (TLR7) agonist that stimulates preferentially the induction of type I interferons.
- Trial name
- NCT01607372
- Testing
- GSK2245035, Type 1 amber glass bottle
- Where
- Canada
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Rhinitis, Rhinitis, Allergic
Short and Mid-term Repeatability of Active Anterior Rhinomanometry (AAR) Measurements in Paediatric Age
Longitudinal, observational study to assess the short-term (test re-test) and mid-term (within the span of 28 days) repeatability of active anterior rhinomanometry (AAR) measures on 4 parallel groups of children with different…
- Conditions
- Rhinitis, Rhinitis, Allergic, Rhinitis, Allergic, Seasonal, Rhinitis, Allergic, Perennial
- Trial name
- Rhino-Rep (NCT03286049)
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Heat Illness, Allergic Rhinitis
Over-the-Counter Antihistamines & Heat Stress
Allergic rhinitis (AR) currently affects ~25% of Canadians, and due to factors of climate change, this number is expected to increase over the coming decade.
- Conditions
- Heat Illness, Allergic Rhinitis, Heat Injury, Sudomotor Sympathetic Dysfunction
- Trial name
- NCT06217367
- Testing
- 50 mg Diphenhydramine, 10 mg Loratadine, 5 mg Desloratadine
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Lakehead University
Type 1 Diabetes, Asthma
EmoTIChealth: Promoting Adolescent Health Through a Serious Game.
The intervention program targets adolescents between 12 and 16 years of age. The intervention program is designed for adolescents during a critical developmental stage marked by significant life transitions, where building strong…
- Conditions
- Type 1 Diabetes, Asthma, Allergic Rhinitis, Food Allergy
- Trial name
- NCT07212530
- Testing
- EmoTIChealth
- Where
- Spain
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Hypersensitivity
DBPC-Dose-finding-trial of Vitamin D3 for SCIT in Birch Pollen Allergic Patients.
Low Vitamin D3 (VD3) levels have been reported to be associated with the risk of allergic diseases like asthma. VD3 has been demonstrated in vitro, ex vivo and in animal models to program the immune system towards…
- Trial name
- BM4SIT (NCT02686827)
- Testing
- Paricalcitol
- Where
- Netherlands
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Laurian Jongejan