Clinical trials: Rhythm
Obesity
KEtogenic Diet and Its Multiple EffectS on Obesity
The prevalence of obesity and metabolic disturbances is worryingly increasing worldwide, therefore the study of their pathophysiology is extremely important to find new strategies for their treatment.
- Trial name
- KEMESO (NCT05898204)
- Testing
- Ketogenic diet, Balanced diet
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- University of Roma La Sapienza
Atrial Fibrillation and Flutter, Atrial Fibrillation
A Clinical Trial of the Use of Remote Heart Rhythm Monitoring With a Smartphone After Cardiac Surgery
The objective of the study is to evaluate the clinical consequences following the detection of postoperative atrial fibrillation or flutter (POAF) using a remote heart rhythm monitoring strategy with a photoplethysmography based…
- Conditions
- Atrial Fibrillation and Flutter, Atrial Fibrillation, Postoperative Complications, Arrhythmia
- Trial name
- SURGICAL-AF 2 (NCT05509517)
- Testing
- Photoplethysmography based smartphone application for heart rhythm analysis (FibriCheck™)
- Where
- Belgium
- Volunteers
- 450 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Heart Failure
Heart Failure and Risk of Re-Admissions Determined by Abnormal REVEAL Parameters
The purpose of the Heart Failure and Risk of re-Admissions Determined by Abnormal REVEAL Parameters (HF RADAR) study is to evaluate the ability of cardiac rhythm (Cardiac Compass) data to predict future cardiac events in heart…
- Trial name
- HF-RADAR (NCT01357408)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Thomas Jefferson University
Epilepsy
Systematic Evaluation of VNS Parameters
The goal of this study is to measure the activation of the vagus nerve and the side effects of vagus nerve stimulation (VNS) (neck muscle contractions, changes in heart rate) across a range of stimulation parameters typically…
- Trial name
- NCT05395026
- Testing
- electrical stimulation of vagus nerve
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Duke University
Endothelial Function
Physiological Assessment of the Endothelium - Circadian Rhythm and Role of the Sympathetic Nervous System
The purpose of this study is to determine whether interventions aimed at increasing sympathetic tone modify endothelial function measures as assessed by the measurement of flow-mediated dilation (FMD) and constriction (FMC).
- Trial name
- PAN (NCT01713374)
- Testing
- Mental stress, no intervention, Myogenic activation
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Parkinson Disease
Evaluation of Ronnie Gardiner Method in Individuals With Parkinson's Disease
Parkinson's disease (PD) is typically associated with cognitive and movement related functional disabilities. One commonly described cognitive complaint is the ability to do several things simultaneously, defined as dual or…
- Trial name
- RGM/PD (NCT02999997)
- Testing
- Ronnie Gardiner Method (RGM)
- Where
- Sweden
- Volunteers
- 51 people
- Sponsor
- University Hospital, Linkoeping
Trauma and Stressor Related Disorders
Electroencephalogram (EEG) Enhanced Transcranial Magnetic Stimulation (eTMS) for Chronic Trauma and Stressor-Related Disorders (TSRD)
The goal of this clinical trial is to learn about the safety, feasibility, and preliminary efficacy of EEG-enhanced transcranial magnetic stimulation (eTMS) as an adjunct to standard-of-care therapies for chronic trauma and…
- Trial name
- ETMS4Stress (NCT05835414)
- Testing
- Adjunctive, midline prefrontal, lower intensity, shorter session, EEG-enhanced, repetitive transcranial magnetic stimulation (eTMS)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Marcia Bockbrader, MD PhD
Alzheimer Disease
The CIRCADIAN Study: Evaluation of Modulating Effect of Galantamine on Circadian Rhythm in Patients With Mild to Moderate Alzheimer's Disease
The purpose of this study is to assess the modulating effect of galantamine on circadian rhythm in patients with moderate Alzheimer's disease.
- Trial name
- NCT01181921
- Testing
- Galantamine
- Where
- Spain
- Volunteers
- 1 people
- Sponsor
- Janssen-Cilag, S.A.
Sleep Disorders, Circadian Rhythm
Efficacy of Ramelteon on Speeding Up Sleep in Subjects With Delayed Sleep Phase Syndrome
The purpose of this study is to evaluate the ability of ramelteon, once daily (QD), to advance the timing of sleep in individuals with delayed sleep phase syndrome.
- Trial name
- NCT00593736
- Testing
- Ramelteon
- Where
- 42 sites in United States
- Volunteers
- 132 people
- Sponsor
- Takeda
Circadian Dysregulation
Body Clocks - Coordination of Peripheral and Central Oscillators
The investigators are conducting an observational trial examining young women over the course of 28 days in which we are monitoring movement, sleep, heart rate, oxygen saturation, gut physiology, light, and menstrual cycle.
- Trial name
- NCT07459764
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Stanford University
Circadian Rhythm Disruption, Healthy Volunteers
Cronobióticos Naturales
Brief Summary The goal of this clinical trial is to learn if a drink made from native berries of southern Chile can change the body's natural production of melatonin (a hormone that helps control sleep), sleep quality, and some…
- Trial name
- ChronoNaturals (NCT07848464)
- Testing
- Chronobiotic
- Where
- Chile
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad San Sebastián
Cerebral Palsy
Rhythm and Multisensoriality's Effects on the Motor Development in Children With Cerebral Palsy
Cerebral palsy (CP) affects the motor function but also the cognitive function of the child. Physical activity brings motor and cognitive benefits and appears as an important aspect of the therapy that is offered to them.
- Trial name
- APP-PaC (NCT03440749)
- Testing
- luminous stimuli
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Cardiovascular Diseases, Atrial Fibrillation, Persistent
Low-voltage Areas Defragmentation in Sinus Rhythm for Radiofrequency Ablation of Persistent Atrial Fibrillation
This is a study evaluating the value of defragmentation of sinus rhythmic low voltage areas in addition to isolation of pulmonary veins in the removal of recurrent atrial fibrillation.
- Trial name
- SCAR-AF (NCT04045067)
- Testing
- Isolation of pulmonary veins, Ablation by radiofrequency of low-voltage areas
- Where
- 9 sites in France
- Volunteers
- 212 people
- Sponsor
- French Cardiology Society
Chronotype, Circadian Rhythm
Chronotype Alignment and Time Perception
People differ in chronotype - whether they function best in the morning ("larks") or the evening ("owls"). This study asks whether the match or mismatch between a person's chronotype and the time of day at which they are tested…
- Conditions
- Chronotype, Circadian Rhythm, Sleep, Time Perception
- Trial name
- NCT07677111
- Testing
- Morning test session (about 08:00), Evening test session (about 22:00)
- Where
- Hong Kong
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Atrial Fibrillation
Impact of New Biomarkers on Maintenance of Sinus Rhythm After Cardioversion or Ablation of Atrial Fibrillation
The Biorhythm study aims to investigate the utility of new biomarkers (e.g. MR proANP, ST2) measured pre-procedure for the prediction of procedural success in patients with atrial fibrillation undergoing cardioversion or ablation.
- Trial name
- Biorhythm (NCT03351816)
- Testing
- Ablation of atrial fibrillation, Cardioversion
- Where
- 3 sites in France
- Volunteers
- 106 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Analgesia Through Mixed Reality
Gamifying Hand Therapy: Development of a Mixed Reality Rhythm Game to Reduce Pain and Improve Motivation
The hand is one of the most functional and frequently injured parts of the body. Without proper recovery, patients can face significant impairments performing everyday tasks.
- Trial name
- NCT07668115
- Testing
- Cold pressor test, Exercise under resistance
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Western University
Defibrillators, Implantable, Myocardial Infarction
Risk of Life-threatening Heart Rhythm Disturbances in Siblings
The purpose of this study is to determine if heredity influences the risk of life-threatening heart rhythms (ventricular tachycardia and ventricular fibrillation) after heart attack (myocardial infarction).
- Conditions
- Defibrillators, Implantable, Myocardial Infarction, Tachycardias, Ventricular
- Trial name
- SIBFIB (NCT00498524)
- Testing
- ICD
- Where
- United States
- Volunteers
- 2,047 people
- Sponsor
- Duke University
Delayed Sleep Phase Disorder, Jet-lag
Melatonin Treatment for Induced Transient Insomnia
Melatonin supplements have been reported to be an effective treatment for circadian rhythm sleep disorders, including shift work dyssomnia, jet-lag, delayed sleep phase syndrome, and sleep disruption suffered by many blind…
- Conditions
- Delayed Sleep Phase Disorder, Jet-lag, Shift-work Disorder
- Trial name
- NCT00950885
- Testing
- Low Dose Melatonin, High Dose Melatonin
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Respiratory Rhythm Disorder
The Effect of Active Breathing Exercises in Stroke Patients With Respiratory Rhythm Disorder
The goal of this clinical trial is to explore The Effect of Active Breathing Exercises in Stroke Patients With Respiratory Rhythm Disorder.
- Trial name
- ABE-S (NCT06265818)
- Testing
- Rehabilitation training, Active Breathing Exercises
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Zeng Changhao
ADHD - Attention Deficit Disorder With Hyperactivity, ADHD
Advancing Identification of Circadian Delay in ADHD Youth: Associations With Clinical Heterogeneity and Cognition
The purpose of this study is to better understand sleep and circadian functioning in children with ADHD using home-based measures, parent report, and a lab based melatonin assessment.
- Trial name
- CIRCA (NCT06971640)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Duke University
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