Clinical trials: Rickets
Vitamin D Deficiency
Effects of Vitamin D Dose and Genotype of the Binding Protein in Infants and Children
The purpose of this study is to determine if the vitamin D binding protein genotype influences circulating vitamin D levels and if it may have functional consequences on vitamin D activity.
- Trial name
- VitaD (NCT01050387)
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Yale University
Rickets
Study to Assess the Use of a Simple Lab Test to Screen for Rickets in Children
Some experts recommend that all breastfed babies receive supplemental vitamin D. The purpose of this study is to determine the rate of vitamin D use in breastfed babies, the recommendations of pediatricians regarding vitamin D…
- Trial name
- NCT00502866
- Where
- United States
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Osteogenesis Imperfecta, Rare Bone Disorders
Morphology in Oral Rare Syndromes & Artificial Intelligence for Clinical Diagnosis
MOSAIC aims to determine whether oro-dental morphological anomalies, particularly palatal morphology, associated with rare bone and cartilage diseases can be precisely characterized using 3D digital models analysed through…
- Conditions
- Osteogenesis Imperfecta, Rare Bone Disorders, Hypophosphatemia, X-Linked
- Trial name
- MOSAIC (NCT07666269)
- Testing
- intra-oral 3D optical impression
- Where
- France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Chronic Kidney Diseases
SOP's for CKD-MBD-Biomarkers
CKD-MBD (Chronic Kidney Disease - Mineral and Bone Disorder) is an extensive disease and includes dysfunction of the mineral metabolism, the bone metabolism and cardiovascular diseases in the context of renal insufficiency.
- Trial name
- NCT02708368
- Testing
- blood withdrawal
- Where
- 2 sites in Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Vitamin D Deficiency
Cholecalciferol Supplementation, Muscle Strength
Hypovitaminosis D is common in Asian Indians despite plenty of sunshine and relates to their skin pigmentation and poor sunshine exposure.
- Trial name
- MRVD (NCT00682214)
- Testing
- Cholecalciferol
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Indian Council of Medical Research
Overweight, Hypovitaminosis D
Effects of Vitamin D Supplementation on Obesity, Inflammatory and Metabolic Markers
46 eligible overweight women with hypovitaminosis D are assigned to either vitamin D or control group using block randomization method.
- Trial name
- NCT05376865
- Testing
- Vitamin D supplement
- Where
- Iran
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Tirang R. Neyestani, Ph.D.
Hypovitaminosis D
The Role of Vitamin D Supplementation on Pain in Women With Primary Dysmenorrhea and Hypovitaminosis D
The purpose of this study is to evaluate the effect of vitamin D supplementation on the pain score of primary dysmenorrhea. Our hypothesis is that by normalizing vitamin D level could help improve pain score of women who have…
- Trial name
- NCT04829487
- Testing
- Ergocalciferol Capsules
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Chronic Kidney Disease Mineral and Bone Disorder
Calcium Balance Studies in Children With CKD and on Dialysis
This is a novel, non-invasive method of assessing Ca balance by natural Ca isotope fractionation.
- Trial name
- Cal-Bal (NCT03285854)
- Testing
- Collection of blood, urine and stool samples
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Hypovitaminosis D, Insulin Resistance
Comparative Effectiveness of Vitamin D and Repletion Strategies
The importance of vitamin D (VitD) in the prevention and treatment of human health conditions has gained increased attention in recent years.
- Conditions
- Hypovitaminosis D, Insulin Resistance, Diabetes
- Trial name
- CEDARS (NCT01524874)
- Testing
- Vitamin D3
- Where
- 2 sites in United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bastyr University
Hypovitaminosis D, Cardiovascular Diseases
Vitamin D Supplementation on in Major Orthopedic Surgery
Prospective, monocentric study in open, aimed at evaluating the effects of supplementation with calcifediol on left ventricular function parameters in cardiopathic subjects undergoing major orthopedic surgery.
- Trial name
- NCT03403933
- Testing
- Didrogyl
- Where
- Italy
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Hypovitaminosis D
To Study the Nutri-Genomic Response of Vit-D Supplementation in African-Americans
Three hundred thirty (330) overweight, pre-hypertensive/controlled hypertensive, African-American participants will be enrolled in a 8 week study to assess the effect of two administrations of Vitamin D3 on Vitamin D serum…
- Trial name
- NCT02802449
- Testing
- 25 Hydroxy- Vitamin D3 [25 (OH) D3]
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Charles Drew University of Medicine and Science
Hypovitaminosis D
Vitamin D Versus Placebo in the Treatment of Vague Musculoskeletal Pain in Children
Other studies suggest that low Vitamin D levels may contribute to musculoskeletal pain. Hypothesis: Administration of oral Vitamin D supplements will improve vague musculoskeletal pain in children.
- Trial name
- NCT00944606
- Testing
- Vitamin D
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of New Mexico
Hypovitaminosis D, Pregnancy Complications
Effect of Vitamin D Replacement on Maternal and Neonatal Outcomes
The optimal vitamin D replacement dose during pregnancy remains undefined. Therefore, the aim of this study is to test the hypothesis that a daily equivalent dose of vitamin D of 3,000 IU/day is needed for Middle Eastern women…
- Conditions
- Hypovitaminosis D, Pregnancy Complications, Infant, Newborn, Diseases
- Trial name
- NCT02434380
- Testing
- Euro D
- Where
- Lebanon
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Vitamin D 25-Hydroxylase Deficiency, Vitamin D Deficiency/Insufficiency
Effects of High-Dose Vitamin D on Hormones, Neuromuscular Function, Cognition, and Body Composition in Athletes
This study aims to evaluate the effects of high-dose vitamin D3 supplementation on selected physiological, neuromuscular, and cognitive parameters in athletes.
- Trial name
- NCT07641075
- Testing
- Vitamin D supplementation
- Where
- Poland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Chronic Kidney Disease Mineral and Bone Disorder
Phosphorus Absorption in Healthy Adults and in Patients With Moderate Chronic Kidney Disease
Chronic kidney disease (CKD) affects approximately 26 million Americans with many more at risk for disease development. Elevated serum phosphorus (P) and related abnormalities in P homeostasis due to progressive loss of kidney…
- Trial name
- NCT03108222
- Testing
- Phosphorus Absorption Test
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Purdue University
Chronic Kidney Disease, Renal Osteodystrophy
Serum Sclerostin Levels, Cardiovascular Parameters and Carpal Tunnel Syndrome in Maintenance Hemodialysis Patients
Sclerostin, the product of the SOST gene, located on chromosome 17, locus q11.2 in humans, was originally believed to be a non-classical Bone morphogenetic protein (BMP) antagonist.Sclerostin was recently identified as a…
- Conditions
- Chronic Kidney Disease, Renal Osteodystrophy, Left Ventricular Hypertrophy
- Trial name
- NCT01382966
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- RFM Renal Treatment Services
Familial Hypophosphatemic Rickets
Calcimimetics in Hypophosphatemic Rickets
Currently, large oral doses of phosphate and 1,25(OH)2D (calcitriol) are the standard treatment of patients with familial hypophosphatemic rickets (XLH).
- Trial name
- CHR (NCT00844740)
- Testing
- Cinacalcet
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Ergocalciferol
Pilot Study: The Effect of Ergocalciferol on Plasma Mucin-1 Levels
To determine if a one-time oral administration of ergocalciferol results in a decline in plasma mucin-1 levels in healthy individuals and individuals with ADTKD-MUC1.
- Trial name
- NCT03747523
- Testing
- Ergocalciferol
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Healthy
Facial Type Determination Through Cephalometry, Anthropometry and Facial Analysis
Introduction: Human face with its bony and muscular structures has singular and peculiar characteristics. It may be classified in three types, associated with the variation of shape and craniofacial configuration, both in…
- Trial name
- NCT00969774
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Catolica de Sao Paulo