Clinical trials: Right Coronary Artery Occlusion
Pulmonary Arterial Hypertension
Pharmacokinetics, Safety and Efficacy of BIA 5-1058 in PAH (Zamicastat)
This Study evaluates the pharmacokinetic (PK) profile of different zamicastat doses in Pulmonary arterial hypertension (PAH) patients to find the most promising therapeutic dosage range for the treatment of PAH disease
- Trial name
- NCT04316143
- Testing
- Oral zamicastat
- Where
- 13 sites in Austria, Germany and 5 more
- Volunteers
- 33 people
- Sponsor
- Bial - Portela C S.A.
Coronary Artery Disease, Stable Angina
Comparison of Left and Right Transradial Approach for CAG and PCI
This trial will compare the procedural success rate between right and left radial approach in patients undergoing coronary angiography and coronary intervention.
- Conditions
- Coronary Artery Disease, Stable Angina, Unstable Angina, Non-ST Elevation Myocardial Infarction
- Trial name
- COMPARE-Rad (NCT03389503)
- Testing
- Radial approach
- Where
- South Korea
- Volunteers
- 322 people
- Sponsor
- Wonju Severance Christian Hospital
Coronary Artery Disease
Pre-procedural 3DCT Versus Angiography Guided PCI for Ostial Right Coronary Artery Lesions
Even with second generation drug eluting stents, rates of target lesion failure (TLF) for aorto-ostial RCA lesions remain high [3yrs TLF 14.2%].
- Trial name
- 3DCT-RCA (NCT05172323)
- Testing
- 3DCT-scan, Angiography guided PCI
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Ziekenhuis Oost-Limburg
Cyanotic Congenital Heart Disease, Right Ventricular Outflow Tract Obstruction
RVOT Stenting Versus Surgical RV-PA Conduit in Cyanotic Adults
This prospective observational cohort study aims to compare clinical and hemodynamic outcomes of percutaneous right ventricular outflow tract stenting versus surgical right ventricle-to-pulmonary artery conduit placement in…
- Trial name
- NCT07866911
- Volunteers
- 30 people
- Sponsor
- Assiut University
Aortic Valve Stenosis, Pulmonary Hypertension
Prognostic Impact of the Evolution of PAH 3 Months After TAVI (HTP-TAVI)
Aortic stenosis (AS) is the most frequent valvulopathy in Western countries. The prevalence of AS is constantly increasing due to the aging of the population.
- Trial name
- HTP-TAVI (NCT04008550)
- Testing
- Right Heart Catheterization
- Where
- France
- Volunteers
- 101 people
- Sponsor
- University Hospital, Rouen
Coronary Artery Disease, Atherosclerosis
Radial Artery Patency and Clinical Outcomes Trial
Coronary Artery Bypass Graft (CABG)Surgery is commonly used to treat patients with coronary artery disease (atherosclerosis) for the relief of angina (chest pain) and improve heart muscle function.
- Trial name
- RAPCO (NCT00475488)
- Testing
- Coronary artery bypass grafting
- Where
- Australia
- Volunteers
- 605 people
- Sponsor
- Austin Health
Myocardial Infarction
Safety and Feasibility of Using a Single Transradial Guiding Catheter for Primary PCI
The Rapid Trial is a randomized-controlled trial proposed to test the hypothesis that using a single guiding catheter for left and right coronary angiography and intervention in patients with ST elevation myocardial infarction…
- Trial name
- RAPID (NCT01759043)
- Testing
- guiding catheter, diagnostic catheter
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Beijing Luhe Hospital
Circulation, Collateral, Coronary Artery Disease
Effect of Permanent Right Internal Mammary Artery Occlusion on Extracardiac Coronary Collateral Supply
Coronary artery disease and the benefit of bypasses: Despite considerable advances in medicine, cardiovascular diseases remain the number one cause of death globally, primarily consequence of myocardial infarction (MI).
- Conditions
- Circulation, Collateral, Coronary Artery Disease, Internal Mammary-Coronary Artery Anastomosis, Ischemia
- Trial name
- IMAOR (NCT03950947)
- Testing
- Amplatzer vascular plug
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Ischemic Heart Disease, Coronary Atherosclerosis
Stress-MRI Assessment After Right Coronary Artery CTO Recanalization
The hypothesis of this study is that Stress-MRI is a clinically significant method of myocardial perfusion assessment after coronary angioplasty with stenting of right coronary artery (RCA) chronic total occlusion (CTO) is…
- Conditions
- Ischemic Heart Disease, Coronary Atherosclerosis, Coronary Artery Disease, Coronary Artery Stenosis
- Trial name
- NCT02769650
- Testing
- CTO coronary angioplasty, Optimal medicamentous treatment, Stress-MRI
- Where
- Russia
- Volunteers
- 72 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Cardiac Surgery Subjects
Effect of PEEP on Cardiac Function
The purpose of this single-center, prospective study is to evaluate the physiologic effect of changes in PEEP on biventricular mechanics and RV-pulmonary arterial (RV-PA) coupling in adult patients undergoing cardiac surgery.
- Trial name
- NCT07531602
- Testing
- EIT Guided PEEP Trial
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Beth Israel Deaconess Medical Center
Coronary Disease, Coronary Artery Ectasia
Outcomes After PCI of the Aneurysmatic Right Coronary Artery
This study aims to evaluate procedural and clinical outcomes of acute coronay syndrome (ACS) patients with aneurysmatic culprit right coronary artery (RCA).
- Conditions
- Coronary Disease, Coronary Artery Ectasia, Right Coronary Artery Occlusion, Right Coronary Artery Stenosis
- Trial name
- RIGHT-MARE (NCT05713201)
- Testing
- Percutaneous Coronary Intervention
- Where
- 8 sites in Italy, Spain
- Volunteers
- 90 people
- Sponsor
- San Luigi Gonzaga Hospital
Hypoplastic Left Heart Syndrome, Total Anomalous Pulmonary Venous Return
Targeting Normoxia in Neonates With Cyanotic Congenital Heart Disease in the Intra-operative and Immediate Post-operative Period
This clinical trial is studying the use of different levels of oxygen exposure during and after cardiopulmonary bypass in eligible infants to learn about its safety during heart surgery.
- Conditions
- Hypoplastic Left Heart Syndrome, Total Anomalous Pulmonary Venous Return, Truncus Arteriosus, Pulmonary Atresia With Ventricular Septal Defect
- Trial name
- T-NOX (NCT04452188)
- Testing
- Normoxia (with controlled re-oxygenation), Standard of care ventilation
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Michigan
Coronary Artery Disease
Comparison Between Right and Left Radial Approach in Patients Undergoing Percutaneous Coronary Procedures
Our aim is to compare between right and left radial approach in patients undergoing percutaneous coronary procedures regarding feasibility and complications.
- Trial name
- NCT05626660
- Testing
- Coronary angiography and percutaneous coronary intervention
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Coronary Artery Bypass Grafting, Coronary Artery Disease
Comparison of RIMA-SVG and Ao-SVG Techniques in Coronary Artery Bypass Grafting
This randomized, double-blind, single-center clinical trial was divided into two groups, RIMA-SVG and Ao-SVG, according to the surgical method.
- Conditions
- Coronary Artery Bypass Grafting, Coronary Artery Disease, Saphenous Vein, Graft Patency
- Trial name
- NCT06787651
- Testing
- RIMA-SVG, Ao-SVG
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Second Hospital of Jilin University
Pulmonary Arterial Hypertension
Safety and Efficacy of BIA 5-1058 in PAH
This study aims to assess the safety and tolerability of the individual highest tolerated zamicastat doses, achieved in the study BIA-51058-201, during long-term treatment in Pulmonary Arterial Hypertension (PAH) disease.
- Trial name
- NCT06009185
- Testing
- Oral zamicastat
- Where
- 11 sites in Austria, Germany and 4 more
- Volunteers
- 20 people
- Sponsor
- Bial - Portela C S.A.
Coronary Artery Disease, Angina Pectoris
Appropriateness of Angioplasty in Patients With Chronic Coronary Syndromes
Percutaneous coronary intervention (PCI) has dramatically changed the treatment of obstructive coronary artery disease patients.
- Trial name
- RIGHT-PCI (NCT06545448)
- Testing
- Percutaneous Coronary Intervention (PCI)
- Where
- Brazil
- Volunteers
- 1,875 people
- Sponsor
- University of Sao Paulo General Hospital
Coronary Artery Disease
Randomized Comparison of JUDkins vs tiGEr Catheter in Coronary Angiography Via the Right Radial Artery: the JUDGE Study
The investigators aim to assess safety and efficiency of Tiger II (5Fr; Terumo Interventional Systems, Somerset, New Jersey) vs Judkins (5Fr; 3.5L/4R, Medtronic Co) catheters, in coronary angiography via the right transradial…
- Trial name
- JUDGE (NCT03042845)
- Testing
- Tiger cardiac catheter, Judkins 3.5L/4R cardiac catheters
- Where
- 2 sites in Greece
- Volunteers
- 640 people
- Sponsor
- University Hospital of Patras
Coronary Artery Disease
Left Versus Right Radial Artery and Radiation Exposure in Patients With Predictors of Trans-radial Failure
The aim of this study is to measure radiation exposure during coronary angiography (CA) with a trans-radial approach (TRA), specifically comparing access via the left versus right radial artery in patients with suggested clinical…
- Trial name
- NCT01707524
- Testing
- Randomized left versus right radial artery approach
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- NYU Langone Health
Heart Failure With Reduced Ejection Fraction, Atrial Fibrillation, Persistent
Pulmonary Artery Pressure and Right Heart Evaluation for Patients Requiring Physiological Pacing Treatment
With the aging of society, the use of cardiac pacing in patients with irreversible bradycardia is increasingly widespread. As early as the 1950s, right ventricular pacing (RVP) began to be used in patients with atrioventricular…
- Conditions
- Heart Failure With Reduced Ejection Fraction, Atrial Fibrillation, Persistent, Sick Sinus Syndrome, Atrioventricular Block
- Trial name
- NCT05575557
- Testing
- Right heart catheterization
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai 10th People's Hospital
Coronary Artery Disease
Graft Patency Analysis of the Right Coronary Artery System
The ideal grafts for the right coronary artery system in coronary artery bypass surgery remain controversial. The objective of this study is to compare the long-term patency of a right gastroepiploic artery and a saphenous vein…
- Trial name
- NCT01559350
- Testing
- A right gastroepiploic artery in situ grafting, A saphenous vein grafting
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Samsung Medical Center