Clinical trials: Risk
Cardiovascular Risk Factor
Choline Supplementation and Cardiovascular Health
Trimethylamine-N-oxide (TMAO), a metabolite produced by gut microbial metabolism of dietary choline, has recently been causally linked to atherosclerosis in animal models and has been shown to be predictive of cardiovascular…
- Trial name
- NCT03646175
- Testing
- Choline
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Body Weight, Obesity
Meta-analysis of the Nordic Dietary Pattern on Cardiometabolic Risk and Cardiovascular Outcomes
The Nordic Diet is a dietary pattern rich in traditional Nordic foods, including berries, grains, and fatty fish common in northern Europe.
- Conditions
- Body Weight, Obesity, Overweight and Obesity, Obesity, Abdominal
- Trial name
- NCT04094194
- Testing
- Nordic diet
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Fraility, Risk of Falling
Physical Activity Monitoring in Frailty and Falling
BioSensics has developed a Physical Activity Monitoring System (PAMSys) that consists of a single wearable motion sensor that is worn on the torso.
- Trial name
- NCT01880229
- Where
- 2 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- BioSensics
Cardiovascular Risk Factor, Cardiovascular Diseases
Health and Cardiovascular Risk Factors in Slums.
Cardiovascular risk factors and disease burden has been showed to affect more deeply to poorer populations. People who live in slums are the most vulnerable subgroup in the populations where, paradoxically scarcity of data exists…
- Trial name
- NCT03734939
- Testing
- None intervention is planned.
- Where
- Argentina
- Volunteers
- 2,265 people, healthy volunteers welcome
- Sponsor
- Fundacion GESICA
Healthy, Overweight
Examining the Longitudinal Relationship Between Sleep and Weight Gain in College Students
This two-year prospective, observational study examines the relationship between habitual short sleep and weight gain, as well as the association between habitual short sleep and behaviors that put people at risk of weight gain.
- Trial name
- STARLIT (NCT04100967)
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Oakland University
Hemolysis
R-FACT Study:Risk Factors for Alloimmunization After Red Blood Cell Transfusions
Alloantibodies can lead to serious clinical consequences and logistic problems like obtaining properly and timely matched blood for the patients who do develop these antibodies.
- Trial name
- R-FACT (NCT01616329)
- Where
- Netherlands
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Sanquin-LUMC J.J van Rood Center for Clinical Transfusion Research
Hypertensive Disorder of Pregnancy
Feasibility and Acceptability of Risk Stratification in the Fourth Trimester to Reduce Maternal Morbidity and Mortality
Hypertensive disorders of pregnancy (HDP) are major causes of maternal morbidity and mortality globally and are associated with peripartum and future cardiovascular disease, including stroke, heart failure, and myocardial…
- Trial name
- NCT05631067
- Testing
- Remote blood pressure monitoring, NT proBNP assessment
- Where
- Nigeria
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Depression, Psychological Distress
A Pilot Study of the Effect of Personalized Depression Risk Communication
Depression is a highly prevalent and disabling mental health problem. It is associated with significant morbidity and mortality and it has a significant economic impact.
- Trial name
- NCT04519892
- Testing
- PDRC, Coach guidance
- Where
- Canada
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Obesity, Fetal Malformation
Obese Pregnant Women: Optimizing Fetal Ultrasound
This study aim to evaluate the quality of fetal ultrasound in obese pregnant women. The hypotheses is that an early ultrasound will improve the quality of the ultrasound in obese.
- Trial name
- NCT02487641
- Where
- Denmark
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Holbaek Sygehus
Smoking
Young Adults and Low Nicotine Cigarettes
The purpose of this study is to look at the effects of investigational low nicotine cigarettes on young adult smokers. The investigators are interested in how using these products affects young adults' perceptions and smoking…
- Trial name
- YLP (NCT03699865)
- Testing
- Nicotine content
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Informed Consent, Health Literacy, Risk, Spinal Puncture, Neurosurgery
Communicating Risks: Consent for Lumbar Puncture
The goal of this randomized control trial is to compare the effect of visual aids on the recall of probabilistic risks in healthy participants.
- Trial name
- NCT05717465
- Testing
- Anatomy diagrams, Standard informed consent
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University College London Hospitals
Gambling
Effects of Positive Psychological Group Psychotherapy and Auricular Acupressure on Withdrawal Symptoms
Objective The purpose of this study is to examine the effects of auricular acupressure and group counseling with positive psychology on gambling severity, withdrawal symptoms, and dopamine.
- Trial name
- NCT05241041
- Testing
- group counseling, auricular acupressure
- Where
- South Korea
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Inha University Hospital
Athletic Performance and Injury Risk
Isometric and Isotonic Hand Strengthening in Competitive Female Badminton Athletes
This randomized clinical trial aims to determine the effects of targeted isometric and isotonic hand strengthening exercises on hand function, dexterity, grip strength and grip endurance in competitive female badminton athletes…
- Trial name
- NCT07438522
- Testing
- Isometric hand strengthening program, Isotonic hand strengthening program
- Where
- Pakistan
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Cognition Disorders in Old Age, Dementia
The "Motoric Cognitive Risk" Syndrome in the Quebec Population
The overall objective of the proposal is to examine the epidemiology of the newly reported "motoric cognitive risk" (MCR) syndrome, which is a pre-dementia syndrome combining subjective cognitive complaint (i.e.; memory…
- Trial name
- NCT03633253
- Testing
- Summarize of participants' characteristics using means and standard deviations or frequencies and percentages
- Where
- Canada
- Volunteers
- 1,741 people, healthy volunteers welcome
- Sponsor
- Jewish General Hospital
Pediatric Obesity, Risk Reduction Behavior
FirstStep2Health Intervention
This project will determine the preliminary efficacy of an innovative intergenerational intervention among Head Start preschoolers, aged 3-5 years, and their caregivers.
- Conditions
- Pediatric Obesity, Risk Reduction Behavior, Early Intervention, Intergenerational Relations
- Trial name
- NCT04164277
- Testing
- Caregiver Component., Caregiver-Preschooler Learning., Center-based Preschooler Component.
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Smoking
Reduced Exposure Study Using THS 2.2 Menthol With 5 Days in a Confinement Setting Followed by 86 Days in an Ambulatory Setting
Evaluate if the ad libitum use of the THS 2.2 Menthol (mTHS), a candidate Modified Risk Tobacco Product, for 5 days in confinement, and after 86 days in an ambulatory setting, by apparently adult healthy smokers results in a…
- Trial name
- NCT01989156
- Testing
- THS 2.2 Menthol (mTHS 2.2), Menthol Conventional Cigarette (mCC), Smoking Abstinence (SA)
- Where
- 2 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Physical Activity, Metabolic Diseases
Effect of a Multicomponent Intervention in Children and Adolescents
The aim of this study was: to evaluate the effectiveness of a multicomponent pilot intervention in improving physical fitness (PF) and metabolic risk markers in children and adolescents; and examine if possible changes in PF are…
- Trial name
- NCT02929472
- Testing
- Physical exercise, without physical exercise
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Clarice Maria de Lucena Martins
HIV Infections, Syphilis
Estimating the Incidence of HIV Infection Among Men Who Have Sex With Men in Peru and Ecuador
The purpose of this observational study is to estimate the number of new HIV infections and the number and variability of antiretroviral-resistant HIV strains among men who have sex with men (MSM).
- Conditions
- HIV Infections, Syphilis, Sexually Transmitted Diseases
- Trial name
- NCT00279331
- Where
- 6 sites in Ecuador, Peru
- Volunteers
- 2,608 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Multiple Sclerosis, Clinically Isolated Syndrome
AT RISK FOR MS - Clinical Conversion of Female Monozygotic Twins Discordant for CIS/MS
The definition of the most 'at-risk' population within highly susceptible groups would provide an opportunity for preemptive therapeutics.
- Trial name
- ARMS (NCT00617383)
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Drive, Recidivism
Teen Driving Translation Study (NIH)
To translate our evidence-based, parent-engagement safe teen driving intervention to a high-risk, rural and urban teen drivers with a traffic violation, and to test the implementation, effectiveness, and cost-effectiveness of the…
- Conditions
- Drive, Recidivism, Communication, Feedback, Psychological
- Trial name
- NCT05696353
- Testing
- In-vehicle Device, Expert-Delivered Parent Communication Training, Peer-Delivered Parent Communication Training
- Where
- United States
- Volunteers
- 588 people, healthy volunteers welcome
- Sponsor
- Ginger Yang
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