Clinical trials: Risk Behaviors
Type 2 Diabetes, Hypertension
Step Monitoring to Improve ARTERial Health
Many people with diabetes and/or high blood pressure (hypertension) are not very active. When people are more active, they can reduce the chances of having a heart attack or stroke.
- Trial name
- SMARTER (NCT01475201)
- Testing
- Step count prescription, Usual care
- Where
- 6 sites in Canada
- Volunteers
- 347 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Atherosclerosis
Long-term Impact Evaluation of a Worksite-based Lifestyle Intervention to Reduce Cardiovascular Risk in Office Workers
The main objective of TANSNIP-PESA is to determine in a population of asymptomatic bank employees with high and low imaging defined cardiovascular disease (CVD) risk the effectiveness of a comprehensive 3-year worksite-based…
- Trial name
- TANSNIP-PESA (NCT02561065)
- Testing
- Lifestyle intervention
- Volunteers
- 1,020 people, healthy volunteers welcome
- Sponsor
- Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III
Health Risk Behaviors
Nitrate INFORMER Nitrosamine Study
Nitrate is a controversial component of vegetables, meat, and drinking water. The now well-established benefits of nitrate, through the enterosalivary nitrate-nitrite-nitric oxide (NO) pathway, on cardiovascular risk factors and…
- Trial name
- NCT05045807
- Testing
- Meat with added nitrate, Meat with added nitrate plus vegetables
- Where
- Australia
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Edith Cowan University
Prevention and Control
PrOVE QUERI Project #1
The overall goal of this project is to test two strategies for implementing a shared decision making tool to be used by providers while talking to patients about lung cancer screening.
- Trial name
- NCT02765412
- Testing
- Webinar, Promotion, and Tool Access, LEAP, Audit and Feedback
- Where
- 8 sites in United States
- Volunteers
- 17,033 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Cancer, Cardiovascular Diseases
Healthy Lifestyles After Cancer for Adolescents and Young Adults: A Program to Reduce Cardiovascular Risk Factors
There are close to 700,000 survivors of adolescent and young adult (AYA) cancer (aged 15 to 39 at diagnosis) in the US. Survivorship for AYAs is often complicated by long-term and late-effects.
- Conditions
- Cancer, Cardiovascular Diseases, Weight Management, Pain
- Trial name
- HEALTHY-AYA (NCT05869604)
- Testing
- HEALTHY AYA, Education Control
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Duke University
Type2diabetes, Heart Failure
Understanding and Addressing Risks of Low Socioeconomic Status and Diabetes for Heart Failure
This study aims to determine whether a 6-month multilevel intervention involving problem-solving training, exercise training and support from community health workers is more effective in improving outcomes for individuals with…
- Conditions
- Type2diabetes, Heart Failure, Obesity
- Trial name
- UNLOAD-HF (NCT06364644)
- Testing
- Community Champions, Homegrown Heroes
- Where
- 2 sites in United States
- Volunteers
- 156 people
- Sponsor
- Johns Hopkins University
Problem Gambling, Gambling Disorder
Responsible Gambling Telephone Intervention to High-risk Gamblers by a State-owned Gambling Operator in Sweden.
The present overall project evaluates an intervention carried out by the Swedish state-owned gambling operator AB Svenska Spel, in order to help high-risk gamblers reduce or quit their gambling.
- Trial name
- NCT04646421
- Testing
- Motivational telephone intervention
- Where
- Sweden
- Volunteers
- 3,626 people
- Sponsor
- Lund University
Suicide, Suicide Ideation
From Hardship to Hope: A Peer-led Intervention to Reduce Financial Hardship and Suicide Risk
Financial hardship is an important risk factor for suicide. However, there are no evidence-based interventions to help individuals at risk for suicide to improve their financial situation.
- Conditions
- Suicide, Suicide Ideation, Suicidal Behavior, Hope
- Trial name
- NCT04840134
- Testing
- From Hardship to Hope: A Peer-led intervention to reduce financial hardship and suicide risk, Enhanced Treatment as Usual (eTAU)
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- New York State Psychiatric Institute
Spinal Cord Injury, Tetraplegia
Effects of Exercise in People With Tetraplegia
This study is designed to assess the impact of exercise and supplementation on measures of fitness, function, and cardiovascular disease risk factors/modifiers in individuals with spinal cord injury (SCI).
- Trial name
- NCT01202019
- Testing
- Circuit Resistance Training (CRT)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Miami
Accidental Falls, Aging
Evaluation of the Effects of a Cognitive-Motor Fall Prevention Program on Fall Risk Factors
The goal of this interventional study is to compare in community dwelling elderly people the effects of two physical activity programs to prevent accident falls : "SILVER XIII EQUILIBRE" program and "VIVIFRAIL" program, on…
- Conditions
- Accidental Falls, Aging, Mild Cognitive Impairment
- Trial name
- 13EVAL (NCT05625828)
- Testing
- Cognitive-motor Physical Activity, Multifactorial Physical Activity
- Where
- France
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- EZUS-LYON 1
Caries, Dental, Risk Reduction
Using a Mouthwash Containing Propolis, Clove Oil and Chlorhexidine to Improve the Caries Risk of High Risk Patients
This study is conducted to determine if using a mouthwash containing propolis, clove oil and chlorhexidine will improve the caries risk of high risk patients in comparison to using a mouthwash containing chlorhexidine only.
- Trial name
- NCT03553628
- Testing
- Chlorhexidine, Propolis and Clove Oil mouthwash, Chlorhexidine mouthwash
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Moataz Gamal Ali Abdul-Maksoud Konsouh
HIV Infections
Implementation and Assessment of a Medication Therapy Management Program in HIV Patients at High Risk of Adverse Drug Events at Khartoum, Sudan
This clinical trial aims to evaluate the effectiveness and cost-effectiveness of two levels of a pharmacist-led Medication Therapy Management (MTM) program, Basic MTM and Enhanced MTM, compared with usual care for HIV patients at…
- Trial name
- HIV-MTM-SUDAN- (NCT07750834)
- Testing
- Basic MTM, Enhanced MTM
- Where
- Sudan
- Volunteers
- 1,149 people
- Sponsor
- Universiti Sains Malaysia
Maternal Health, Infant Health
Stress Reactivity and Mother-Infant Cardiovascular Disease Risk
Prenatal Mindfulness training (MT) shows promise as a preventive intervention against hypertensive disorders of pregnancy (HDP) and may reduce risk for offspring cardiovascular disease (CVD).
- Conditions
- Maternal Health, Infant Health, Hypertension, Behavioral Medicine
- Trial name
- NCT06805799
- Testing
- Follow up to Mindfulness RCT using a Still Face Paradigm
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lifespan
Child Adiposity
Early Child Care and Risk of Obesity
The purpose of this study is to examine risk factors associated with infant growth and the development of obesity in the first year of life.
- Trial name
- Nurture (NCT01788644)
- Where
- United States
- Volunteers
- 860 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Diabetes Mellitus Type 2, Sarcopenia
A Theory-based Home-based Multi-component Exercise Training Among Older Adults With Type 2 Diabetes Mellitus
The goal of this clinical trial is to learn if a theory-based home-based multi-component exercise training works to prevent sarcopenia in older adults with type 2 diabetes mellitus.
- Trial name
- NCT06393244
- Testing
- a theory-based home-based multi-component exercise training
- Where
- China
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Cheng Li
Cancer Prevention, Firefighters
Behavior and Risk Awareness Through Video Education for Firefighters
The goal of this clinical trial is to evaluate the impact of short documentary-style videos to educate and inspire firefighters to take safety measures to prevent cancer incidence and mortality.
- Trial name
- BRAVE (NCT07494617)
- Testing
- Video 1, Video 2, Video 3
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Cardiovascular Diseases
HOPE-CVD-Virtual: A Virtual Trial to Evaluate the Primary Prevention of CVD
This 4-arm (1:1:1:1) single-blind randomized controlled trial. Arm 1 will communicate risk and encourage behavioral change that mirrors the standard pathway for health screening in Singapore.
- Trial name
- NCT05827861
- Testing
- HeartAge, HOPE-CVD Mobile App, Genetic Risk Score
- Where
- Singapore
- Volunteers
- 1,121 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Hypoxic-Ischemic Encephalopathy, Hypoglycemia
Quantitative Assessment of Sucking for Early Diagnosis of Brain Injury in Infants at High Risk
The main goal of this study is to quantitatively assess the sucking and feeding activity of infants at high risk of neurological impairment (preterm infants and term infants at risk of abnormal neurodevelopment) during oral…
- Conditions
- Hypoxic-Ischemic Encephalopathy, Hypoglycemia, Neonatal Abstinence Syndrome
- Trial name
- NCT03246243
- Testing
- nfant feeding solution
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Cardiovascular Risk Factor, Sedentary Lifestyle
The Effects of Faculty/Staff Exercise Program
This study focuses on analyzing the data collected from participants in the Faculty/Staff Exercise Program to determine the success and quantifying the results of the program.
- Conditions
- Cardiovascular Risk Factor, Sedentary Lifestyle, Physical Activity
- Trial name
- NCT03385447
- Testing
- Physical Activity
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kent State University
Accidental Falls, Sedentary Lifestyle
Developing a Intervention to Enhance Motivation for Physical Activities Known to Reduce Fall Risk
The purpose of this pilot study is to develop an intervention, based on empirical evidence and health-related behavioral change theory, to enhance motivation for engaging in fall-reducing physical activities.
- Trial name
- ReadySteady (NCT02433249)
- Testing
- 1 Physical Activity, Interpersonal Motivation, Intrapersonal Motivation
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Minnesota