Clinical trials: Risk Reduction
Hypertension
Cornell Translational Behavioral Science Research Consortium: Hypertension Qualitative Study
To explore the meaning, causes and treatment of hypertension in eligible patients. In addition the cultural, social, and psychological factors that either facilitate or serve, as barriers to behavioral change will be illuminated…
- Trial name
- NCT00227175
- Testing
- Semi-structured, open ended interview
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Weill Medical College of Cornell University
Depression, Coronary Artery Disease
Effects of a Psychotherapy Intervention in Depressed Patients With Coronary Artery Disease
In patients with coronary artery disease (CAD), depressive symptoms are frequent and highly relevant for quality of life, health behaviour, health care costs, and prognosis.
- Trial name
- SPIRR-CAD (NCT00705965)
- Testing
- Psychotherapy, Information session, Usual cardiological care
- Where
- 10 sites in Germany
- Volunteers
- 570 people
- Sponsor
- University of Göttingen
Heart Diseases, Hiv
Whole Food Plant-Based Diet for HIV-Associated Reduction in Cardiovascular Risk (PLANT-HART)
The goal of this clinical trial is to evaluate the impact of using a whole food plant-based diet in the reduction of cardiovascular risk related to HIV in people who live with HIV infection.
- Trial name
- PLANT-HART (NCT05796882)
- Testing
- Whole Food Plant-Based Diet Ad Libitum, Nutritional Standard Care
- Where
- Mexico
- Volunteers
- 10 people
- Sponsor
- Universidad Autonoma de Chihuahua
Adolescent Mothers, Infant Obesity
Tools For Teen Moms: Reducing Infant Obesity Risk
The purpose of this social media group randomized trial (GRT) is to test the feasibility of our Baby Dayr for Teen Moms intervention to increase maternal responsiveness to infant cues and implement healthy feeding practices…
- Trial name
- TFTM (NCT02244424)
- Testing
- Tools for Teen Moms
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Michigan State University
Type 2 Diabetes, Food Insecurity
The Food for Health Study
The project, called Food for Health (F4H), will study a new Produce Prescription Program (PPP) designed for rural Native American older adults.
- Conditions
- Type 2 Diabetes, Food Insecurity, Rural Health
- Trial name
- F4H (NCT07254689)
- Testing
- Produce Prescription Program
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Montana
Hypercholesterolemia, Cardiovascular Diseases
Trial to Evaluate Efficacy and Safety of LIB003, Evolocumab and Alirocumab in High-risk CVD Patients
Comparison of LDL-C reductions at Week 12 of monthly (Q4W[≤ 31 days]) dosing of LIB003 300 mg administered subcutaneously (SC) to Q4W dosing of evolocumab (Repatha) 420 mg and alirocumab (Praluent) 300 mg in patients with CVD or…
- Trial name
- LIBerate-H2H (NCT04790513)
- Testing
- lerodalcibep, evolocumab, alirocumab
- Where
- 3 sites in United States
- Volunteers
- 204 people
- Sponsor
- LIB Therapeutics LLC
HIV Risk Behaviors
Sustainable HIV Risk Reduction Strategies for CJ Systems
The purpose of the Texas Christian University (TCU) Disease Risk Reduction (DRR) Project is to develop and test an intervention designed to increase positive decision-making skills among offenders for healthy living, including…
- Trial name
- DRR (NCT01900210)
- Testing
- WaySafe
- Volunteers
- 1,396 people, healthy volunteers welcome
- Sponsor
- Wayne Lehman
Behavior and Behavior Mechanisms
A Parent-Based Intervention to Reduce Sexual Risk Behavior in Adolescents
The purpose of this study is to test the feasibility and efficacy of a triadic intervention designed to target both healthcare providers and parents in order to prevent adolescent sexual risk behavior in Latino and African…
- Trial name
- NCT01326806
- Testing
- Families Talking Together, Active Control on Hygiene & Nutrition
- Where
- United States
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- New York University
Abnormal Uterine Bleeding, Unspecified
Prophylactic Bilateral Salpingectomy and Laparoscopic Myomectomy
We already demonstrated that the addiction of PBS to Total Laparoscopic Hysterectomy (TLH) has no negative effects in term of ovarian function, evaluated by anti-Müllerian hormone (AMH), Follicle Stimulating Hormone (FSH), Antral…
- Trial name
- NCT01929148
- Testing
- Prophylactic bilateral salpingectomy, Laparoscopic myomectomy without PBS
- Where
- Italy
- Volunteers
- 154 people
- Sponsor
- University Magna Graecia
Suicidal Ideation, Suicidal Behavior
Multimodality Adaptive Intervention for Post-Inpatient Hospitalization Suicide Risk Reduction
The goal of this clinical trial is to learn whether a combination of brief digital and clinician-delivered interventions can help adults leaving a psychiatric hospitalization cope with suicidal thoughts and prevent…
- Trial name
- NCT06764108
- Testing
- Self-monitoring, JITAI, Self-guided SSI
- Volunteers
- 360 people
- Sponsor
- Massachusetts General Hospital
Sugar Sweetened Beverage Consumption, Nutrition
Testing Message Modality of Culturally Appropriate Nutrition Communication for Mexican American Women
A randomized controlled trial to test the effects of culturally appropriate nutrition communication delivered via different modalities for Mexican American women.
- Conditions
- Sugar Sweetened Beverage Consumption, Nutrition, Lifestyle-related Condition, Lifestyle Risk Reduction
- Trial name
- NCT04710108
- Testing
- Health Communication
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- University of California, Merced
Hiv, HIV Infections
Personalized Prevention for Couples: A 16-month Digital RCT
This couples-based, digital health intervention project is serostatus neutral and seeks to determine efficacy for: a) use and adherence to evidence-based HIV/STI prevention-care strategies; b) creation and adherence to a tailored…
- Conditions
- Hiv, HIV Infections, Sexually Transmitted Infection, Sexually Transmitted Diseases
- Trial name
- LuvHub (NCT05708014)
- Testing
- Intervention LuvHub, Waitlist Control LuvHub
- Where
- United States
- Volunteers
- 778 people, healthy volunteers welcome
- Sponsor
- Florida International University
Cervical Intraepithelial Neoplasia Grade I/ II/ III (CIN I/II/III), Human Papillomavirus (HPV) Infections
A Study to Assess the Reduction of Human Papillomavirus (HPV) Viral Infectivity and Transmission in HPV-Positive Women After Vaccination With 9vHPV (RIFT-HPV)
This is a non-randomized, open label study to assess the reduction of Human Papillomavirus (HPV) infectivity and transmission in women positive for HPV16 and/or 18 in a cervical, oral and anal sample and vaccinated with…
- Conditions
- Cervical Intraepithelial Neoplasia Grade I/ II/ III (CIN I/II/III), Human Papillomavirus (HPV) Infections, High-risk HPV, HPV-16/ 18
- Trial name
- RIFT-HPV (NCT05334706)
- Testing
- Nonavalent HPV vaccine (9vHPV/Gardasil-9™).
- Where
- Spain
- Volunteers
- 69 people
- Sponsor
- Miquel Angel Pavon Ribas
Pneumonia, Postoperative, Anesthesia
Reducing Pneumonia with LMA in Lung Wedge Resection
This retrospective cohort study aims to evaluate whether spontaneous breathing laryngeal mask anesthesia (LMA-SBA) reduces the incidence of postoperative pneumonia compared to single-lung isolation mechanical ventilation in…
- Conditions
- Pneumonia, Postoperative, Anesthesia, Thoracic Surgery, Thoracoscopic Wedge Resection
- Trial name
- NCT06873958
- Where
- China
- Volunteers
- 700 people
- Sponsor
- Hai Feng
Cancer, Cardiovascular Diseases
ActivityChoice: Implementing Clinic-Based Physical Activity Program Choices for Cancer Survivors
Cardiovascular disease, the number one leading cause of death in the United States, is highly prevalent in cancer survivors. Physical activity can reduce risk, and referrals to programs addressing survivors' choices are highly…
- Conditions
- Cancer, Cardiovascular Diseases, Physical Inactivity
- Trial name
- NCT05870176
- Testing
- Enhanced Referral, Standard Referral
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Unsafe Sex, Physical Violence
HIV/STI Risk Reduction for Incarcerated Women With Interpersonal Violence
The pilot study aims to conduct a randomized pilot trial in a sample of 40 incarcerated women with lifetime interpersonal violence who are 6-10 weeks away from release to demonstrate the feasibility and acceptability of the…
- Conditions
- Unsafe Sex, Physical Violence, Sexual Assault, Sexual Abuse
- Trial name
- NCT01907126
- Testing
- Nutrition Program (NP), Women's Prison CoOp (WPC)
- Where
- 3 sites in United States
- Volunteers
- 42 people
- Sponsor
- Brown University
Worksite Health Promotion, Lifestyle Risk Reduction
Intervention to Increase Physical Activity and Wellbeing Among Staff and Residents in Assisted Living Facilities
The purpose of the study is to test a program that aims to help staff increase wellness behaviors and test the impact of this program on staff and work outcomes.
- Conditions
- Worksite Health Promotion, Lifestyle Risk Reduction, Occupational Burnout, Healthcare Workers
- Trial name
- WHHIP+FFC 2026 (NCT07785947)
- Testing
- WHHIP, FFC
- Where
- United States
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Obesity, Cardiovascular Diseases
High-intensity Exercise Training or Multidisciplinary Treatment in Extremely Obese Adolescents
The aim of the present study was to determine the effects of a multidisciplinary approach and intensity-controlled interval training on cardiovascular risk factors in overweight adolescents
- Trial name
- NCT00682266
- Testing
- intensity controlled interval training (AIT), Multidisciplinary approach (MTG)
- Where
- Norway
- Volunteers
- 54 people
- Sponsor
- Norwegian University of Science and Technology
HIV Infections
Specialized Cognitive-Behavioral Counseling Intervention to Reduce HIV Transmission Risk Behavior in HIV-Infected Men
This study will evaluate the effectiveness of a specialized cognitive-behavioral counseling intervention in reducing sexual risk behaviors in men who are HIV-infected and report having unprotected sex with male partners who are…
- Trial name
- NCT00218712
- Testing
- Cognitive behavioral intervention, Standard counseling
- Where
- 2 sites in United States
- Volunteers
- 488 people
- Sponsor
- University of California, San Francisco
Sexual Violence
Efficacy of a Web-based Sexual Violence Risk Reduction Program for Female College Students
This study evaluates the efficacy of a web-based program for female college freshmen ("RealConsent") in reducing their risk of sexual violence victimization.
- Trial name
- RealConsent (NCT03726437)
- Testing
- RealConsent, Stress and Mood Management
- Where
- United States
- Volunteers
- 881 people, healthy volunteers welcome
- Sponsor
- Georgia State University