Clinical trials: Risk Reduction Behavior
Abdominal Obesity
Effects of Weight Reduction on Sleep and Alertness in Long-distance Truck and Bus Drivers
The study is a year-long health-behaviour intervention in obese, male truck-drivers to lose weight moderately by 10%, using monthly individual counseling.
- Trial name
- SF-Truck (NCT00893646)
- Testing
- weight loss counseling
- Where
- 3 sites in Finland
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- UKK Institute
Smoking
Reduced Exposure Study in Smokers Using the Tobacco Heating System 2.2 (THS 2.2) for 5 Days in a Confinement Setting
The overall goal of the study is to evaluate if the ad libitum use of the Tobacco Heating System 2.2 (THS 2.2) for 5 consecutive days by adult Japanese healthy smokers affects the levels of biomarkers of exposure for selected…
- Trial name
- NCT01970982
- Testing
- Tobacco Heating System (THS 2.2), Smoking abstinence (SA), Conventional cigarette (CC)
- Where
- Japan
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Fall
Intervention on Reducing Risk of Falls Among Community Dwelling Older Adults in Selangor
Falls is a major concern in geriatrics due to its high prevalence and various adverse health complications among elderly population.
- Trial name
- NCT05863143
- Testing
- Nutritional and Exercise
- Where
- Malaysia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Mild Cognitive Impairment
VR-CogMoBal Training for Reducing Falls Among Older Adults With Mild Cognitive Impairment
Older adults often display gait instability, impaired balance control and cognitive decline that lead to falls and fall risks. Approximately 60% of the elderly people with cognitive deficits experience a detrimental fall each…
- Trial name
- NCT03765398
- Testing
- VR Cognitive-motor-balance training
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Illinois at Chicago
Opiate Dependence, HIV Infections
HIV Risk Reduction and Drug Abuse Treatment in Iran
A randomized, double blind clinical trial comparing buprenorphine and naltrexone maintenance treatment when combined with drug abuse and HIV risk reduction counseling (DC-HIV) for heroin and opium addicts in Iran.
- Trial name
- NCT00398008
- Testing
- Buprenorphine/Subutex, Naltrexone, Drug counseling
- Where
- 2 sites in United States, Iran
- Sponsor
- Yale University
Smoking
Combined Treatment for Tobacco and Alcohol Use in Puerto Rico
Objectives: 1. Assess MAPS and MAPS+ effects on alcohol at-risk behaviors and smoking cessation. 2. Assess MAPS and MAPS+ effects on treatment mechanisms (increased self-efficacy, decreased temptations/craving, decreased stress…
- Trial name
- NCT00570804
- Testing
- Telephone Counseling, Telephone Assessments
- Where
- United States
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Type 1 Diabetes, Hypoglycemia
Slow Digestible Carbohydrates and Exercise in Adolescents With Type 1 Diabetes
In this within-subject cross-over study, the investigators hypothesize that corn-starch based supplements taken prior to exercise will decrease the risk of delayed hypoglycemia in adolescents with T1D, improve performance during…
- Trial name
- NCT05540132
- Testing
- maltodextrin, super starch
- Where
- United States
- Sponsor
- State University of New York at Buffalo
High Risk for Breast Cancer, Risk Reduction Behavior
Facilitating Web-based Patient Decision Support: Decision About Medication to Lower Breast Cancer Risk
Background: Chemoprevention is the use of preventive medications to reduce the risk of breast cancer for women who are at a high risk of developing the disease.
- Trial name
- NCT00906321
- Testing
- Web-Based Decision Support
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- National Cancer Institute (NCI)
Sexually Aggressive Behavior, Risky Sexual Behavior
Alcohol And Sexual Risk Behavior
The current study proposes to develop, refine, and conduct a preliminary randomized controlled trial (RCT) of an innovative prevention program that is the first to (a) simultaneously target heavy episodic drinking (HED), sexually…
- Conditions
- Sexually Aggressive Behavior, Risky Sexual Behavior, Heavy Episodic Drinking
- Trial name
- PNF (NCT04416711)
- Testing
- Personalized Feedback, Cognitive Skills Training, Services As Usual
- Where
- 2 sites in United States
- Volunteers
- 108 people
- Sponsor
- Arizona State University
Depression
Reducing Fetal Exposure to Maternal Depression to Improve Infant Risk Mechanisms
This study evaluates Interpersonal Therapy (IPT) in the treatment of depression among pregnant women with elevated depressive symptoms.
- Trial name
- NCT03011801
- Testing
- Interpersonal Therapy, Enhanced usual care
- Where
- 2 sites in United States
- Volunteers
- 234 people
- Sponsor
- University of Illinois at Urbana-Champaign
Cardio Vascular Disease, Cerebro Vascular Disease
Qungasvik (Toolbox)-Healthy Hearts: A Cultural Approach to Reducing Chronic Disease Risk
Due to the extreme remoteness, transportation challenges, and lack of access to clinical care, the delivery of preventative health interventions in rural Alaska Native communities is a top tribal priority.
- Conditions
- Cardio Vascular Disease, Cerebro Vascular Disease, Mental Health, Chronic Disease (Physical)
- Trial name
- AK CEAL EI (NCT07829341)
- Testing
- Qungasvik-Healthy Hearts
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Alaska Fairbanks
Risk Reduction Through Family Therapy, Usual Care
Risk Reduction for Drug Use and Sexual Revictimization
The investigator proposes to evaluate Risk Reduction through Family Therapy (RRFT), which integrates: 1) an ecologically-based intervention for treatment of substance abuse behaviors in high risk adolescents, 2) exposure-based…
- Trial name
- RRFT (NCT00998153)
- Testing
- Risk Reduction through Family Therapy
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Medical University of South Carolina
HIV, HIV Infections
Positive Lifestyles Using Safety
Project PLUS tests an HIV risk reduction/adherence behavioral intervention with HIV-infected individuals in Connecticut prisons.
- Trial name
- Project PLUS (NCT00836290)
- Testing
- Pre-Release (Group 1), Post-release (Group 2)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Yale University
HIV Prevention, Pre-exposure Prophylaxis (PrEP)
A Study Evaluating An Integrated Pharmacy Digital Diary and Delivery Strategy to Increase PrEP Use Among MSM and TGW
The PrEP 3D randomized controlled trial (RCT) will study the effectiveness of the PrEP-3D app compared to standard of care for starting pre-exposure prophylaxis (PrEP), continuing PrEP, and adherence to PrEP.
- Conditions
- HIV Prevention, Pre-exposure Prophylaxis (PrEP), Risk Reduction, Adherence, Medication
- Trial name
- PrEP-3D RCT (NCT05474313)
- Testing
- PrEP-3D package, Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Public Health Foundation Enterprises, Inc.
Substance Use, Sexual Risk Behavior
Substance Use and Sexual Risk Reduction Intervention for Homeless Youth
The goal of this study is to evaluate a group-based motivational interviewing (MI)-delivered risk reduction program for homeless young adults.
- Trial name
- NCT02188797
- Testing
- Group MI risk reduction program
- Where
- 2 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- RAND
Opioid-Related Disorders
The OPT-IN Project
Prescription opioid overdose represents a public health crisis. A number of efforts have been implemented to address opioid prescribing and opioid risk mitigation strategies for prescribers, but relatively few efforts have sought…
- Trial name
- NCT03526380
- Testing
- Behavioral: the OPT-IN Intervention
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- University of Michigan
Breast Cancer, Smoking Cessation
Brief Intervention for Tobacco and Alcohol Risk Reduction for Couple During Breast Cancer Treatment.
This study will examine the benefits of involving partner in a Screening, Brief Intervention and Referral to Treatment (SBIRT) program for tobacco and alcohol for women treated for breast cancer.
- Conditions
- Breast Cancer, Smoking Cessation, Alcohol Use, Unspecified
- Trial name
- IBMC (NCT04007549)
- Testing
- Brief motivational interview on tobacco/alcohol risk reduction
- Where
- France
- Sponsor
- Institut Bergonié
Metabolic Disease, Cardiovascular Diseases
HYPERtension Reduction Through WALKing Stairs Versus Brisk Walking
This clinical trial investigates whether incorporating stair walking into daily routines improves physical health in adults at risk of lifestyle-related conditions such as hypertension, type 2 diabetes, and cardiovascular…
- Conditions
- Metabolic Disease, Cardiovascular Diseases, Hypertension, Obesity and Overweight
- Trial name
- HYPERWALK (NCT06952348)
- Testing
- Stair and brisk walking combined, Brisk walking, Standard care
- Where
- 4 sites in Sweden
- Volunteers
- 450 people
- Sponsor
- Karolinska Institutet
Life Style, Healthy, Risk Reduction
Digital Engagement for Lifelong Health
The DELPHI project (Digital Engagement for Lifelong Prevention and Health Improvement) aims to develop, implement, and validate an advanced digital platform for promoting well-being and personalized prevention of chronic…
- Conditions
- Life Style, Healthy, Risk Reduction, Health Promotion
- Trial name
- DELPHI (NCT07612852)
- Testing
- DELPHI Personalized Digital Prevention Platform, Passive Digital Monitoring Control
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Life Style, Healthy, Life Style
A Randomized-Controlled Lifestyle Intervention to Increase Physical Activity Levels in Adolescents
Students at the age of 14-16 years will be randomized to one intervention arm or one control arm in a 1:1 ratio. Participants of both groups receive a fitness tracker to count the amount of their steps taken.
- Trial name
- healthy tyrol (NCT04749004)
- Testing
- Promotion of physical activity
- Where
- Austria
- Volunteers
- 373 people, healthy volunteers welcome
- Sponsor
- VASCage GmbH