Clinical trials: Risk of Aspiration
Healthy Participants
Gastric Volume Estimation by Ultrasonography After Glucose Loaded Clear Fluid Ingestion in Fasted Adult
Introduction; Pre operative gastric ultrasonography is a newly developed tool used to evaluate gastric content and volume in assessing perioperative aspiration risk and guide anaesthetic management.
- Trial name
- NCT04478435
- Testing
- glucose loaded clear fluid
- Where
- Malaysia
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Resilience, Anxiety
Music Breathing in Enhancing Resilience Among Elders at Risk of Mental Health Problems
The goal of this pilot randomised controlled trial is to examine the effects of a mindfulness-based music breathing intervention in enhancing resilience (primary outcome), and in reducing anxiety, depressive symptoms, loneliness…
- Conditions
- Resilience, Anxiety, Depressive Symptom, Loneliness
- Trial name
- NCT07631845
- Testing
- Mindfulness-based music breathing intervention, control group
- Where
- Hong Kong
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Gastric Contents
Bedside Ultrasound of Gastric Contents in Pediatric Populations
Perioperative aspiration of gastric contents is a rare but serious adverse event. The risk of aspiration can be estimated by perioperative evaluation of stomach contents with ultrasound using a validated technique and scoring…
- Trial name
- NCT03520374
- Testing
- Ultrasonography
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stanford University
Head and Neck Neoplasms, Swallowing Sparing IMRT
The SWOAR Trial Sparing of Swallowing and Aspiration Related Organs at Risk & Submandibular Gland With Intensity Modulated Radiotherapy Versus Standard IMRT in Head and Neck Squamous Cell Carcinomas
The aim of SWOAR TRIAL is to test sparing of Dysphagia/ Aspiration risk structures (DARS) and contra lateral submandibular gland by IMRT.
- Trial name
- SWOAR (NCT05187091)
- Testing
- Swallowing and submandibular sparing IMRT, Standard IMRT with medical CRT/RT, Cisplatine
- Where
- India
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences
Pulmonary Microaspiration
Microaspiration in ERCP
Endoscopic retrograde cholangiopancreatography (ERCP) is considered the gold standard in diagnosing and treating biliary and pancreatic diseases.
- Trial name
- NCT04831489
- Testing
- Imaging
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Theodor Bilharz Research Institute
Opioid Induced Swallowing Disorders
Opioid Induced Swallowing Difficulties and Risk for Pulmonary Aspiration
The purpose of this study is to determine weather remifentanil induced swallowing difficulties increase risk for pulmonary aspiration.
- Trial name
- NCT01495377
- Testing
- Remifentanil, Technetium, Dynamometer (Jamar)
- Where
- 2 sites in Sweden
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Acute Pulmonary Embolism
Comparing Three Catheter Aspiration Strategies for Intermediate-High-Risk Acute Pulmonary Embolism
Acute pulmonary embolism (PE) is a serious and potentially life-threatening condition in which blood clots block the arteries of the lungs.
- Trial name
- NCT07869875
- Testing
- Small-bore (8-12 F) percutaneous catheter aspiration, Large-bore (16 F or larger) percutaneous catheter aspiration thrombectomy, Combined large-bore and small-bore percutaneous catheter aspiration
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Qiu Jipeng
Pulmonary Aspiration, Emergency Surgery
Aspiration Risk Assessment by Gastric Ultrasound in eMErgency Surgery and ANesThetic Decision-making: The ARGUMENT Study
Pulmonary aspiration of gastric contents is a serious patient safety problem accounting for 50% of anesthesia-related mortality.
- Trial name
- NCT06303492
- Testing
- GUS
- Where
- Canada
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Anxiety, Decision Making
Impact of Anxiety on the Decision-making Processes of Anesthesiologists
Except for exaggerated situations in which aspiration risk seems obvious (or absent), the choice of a rapid sequence induction protocol for general anesthesia is often made under uncertainty, according to the individual…
- Conditions
- Anxiety, Decision Making, General Anesthesia
- Trial name
- DECIDINH (NCT05364801)
- Testing
- Survey
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Breast Cancer
High Risk Breast Clinic: Protocol for Women at Increased Risk for Developing Breast Cancer
The overall goal of this project is to develop an integrative system of breast cancer risk assessment based on epidemiologic and biologic risk variables, as well as to develop or refine risk biomarkers which may be useful in…
- Trial name
- NCT00291096
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Carol Fabian, MD
Dysphagia, Healthy Aging
Swallowing Impairments in ICU Survivors and Community-Dwelling Adults
Post-intensive care syndrome (PICS), which consists of physical, cognitive, and psychosocial problems, is a pervasive complication for older intensive care unit (ICU) survivors and contributes to detrimental health outcomes and…
- Conditions
- Dysphagia, Healthy Aging, Post Intensive Care Syndrome, Caregiver Burden
- Trial name
- NCT07005037
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Breast Cancer, Healthy, no Evidence of Disease
Study of Breast Tissue in Women Not Previously Diagnosed With Breast Cancer Who Are Undergoing Fine Needle Aspiration
RATIONALE: Studying samples of blood and breast tissue from healthy women in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to breast cancer risk.
- Trial name
- NCT00896636
- Testing
- Random fine need aspiration (rFNA), Mammogram
- Where
- United States
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Pulmonary Aspiration of Gastric Contents
SMART Study (Sellick's Maneuver Assisted Real Time) to Deliver Target Cricoid Pressure in Simulated Environment
Cricoid force is applied during airway management to prevent pulmonary aspiration of regurgitated gastric contents. This force is usually applied by a nurse or anaesthesia assistant.
- Trial name
- NCT02749175
- Testing
- Cricoid force sensor monitor system
- Where
- Singapore
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Breast Cancer
Protocol for Postmenopausal Women at Increased Risk of Developing Breast Cancer
To examine nipple aspirate fluid for secretions that may be identified as a high risk indicator for development of breast cancer, and compare those to serum analysis.
- Trial name
- NCT00291083
- Where
- United States
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Carol Fabian, MD
Postoperative Pulmonary Atelectasis, Postoperative Pulmonary Complications
Driving Pressure During Surgeries With High Risk for Postoperative Pulmonary Complications
The goal of this clinical trial is to compare two different types of perioperative mechanical ventilation (MV), specifically Protective Mechanical Ventilation (PMV) and MV with the lowest possible Driving Pressure (ΔP), in…
- Conditions
- Postoperative Pulmonary Atelectasis, Postoperative Pulmonary Complications, Postoperative Respiratory Failure, Postoperative Bronchospasm
- Trial name
- NCT07186933
- Testing
- PEEP titration for Minimum Driving Pressure, Lung Protective Ventilation
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University General Hospital of Patras
Anxiety, Panic Disorder
Ventilatory Physiology in Children at Risk for Anxiety
The importance of the proposed research project derives from a steady accumulation of research findings on the relationship between respiration and anxiety.
- Trial name
- NCT00101777
- Where
- United States
- Volunteers
- 479 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Breast Cancer
RPFNA Assessment of Exercise Effect in Breast Cancer
This study is being done to see if the investigators can measure changes that occur in breast tissue when women at risk of developing breast cancer start an exercise program.
- Trial name
- NCT01961128
- Testing
- Exercise Intervention
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Breast Cancer
LY353381 in Preventing Breast Cancer in Women With Hyperplasia
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of LY353381 may be an effective way to prevent the development of breast cancer in women who have…
- Trial name
- NCT00005879
- Testing
- arzoxifene
- Where
- 2 sites in United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Refractive Surgery
Risk Factors for Progressive Suction Loss in Corneal Refractive Surgery
The goal of this Prospective observational studiesis to Characteristics of progressive suction loss.
- Trial name
- NCT06264804
- Where
- China
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Yifeng Yu
Microaspiration, Acute Respiratory Distress Syndrome (ARDS)
Does Cricoid Pressure Reduce the Risk of Aspiration?
In modern anesthesia practice, the application of cricoid pressure during intubation is not infrequently used with the goal of preventing gastric-to-pulmonary aspiration.
- Conditions
- Microaspiration, Acute Respiratory Distress Syndrome (ARDS), Hospital Acquired Pneumonia
- Trial name
- NCT02058004
- Testing
- Cricoid pressure
- Where
- 2 sites in United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic