Clinical trials: Risk of Fracture
Postmenopausal Osteopenia
Effects of Kinect-based Virtual Reality Training in Postmenopausal Women With Osteopenia
Osteopenia is a clinical term to define the declined Bone Mineral Density (BMD) as per the normal reference values but not low enough to meet osteoporotic diagnostic criteria.
- Trial name
- NCT04862910
- Testing
- Kinect Based Virtual Reality Training, Control Group
- Where
- 2 sites in Pakistan
- Volunteers
- 52 people
- Sponsor
- Riphah International University
Fall, Fall Patients
Identifying Risk Factors for Falls in Patients With a High Risk of Fracture Using Connected Insoles (FeetMe Monitor® Device)
The objective of this study is to determine which gait parameters measured at home using e FeetMe® Insoles are associated with a risk for falls in a patient population suffering from osteoporosis and a higher with high risk of…
- Conditions
- Fall, Fall Patients, Osteoporosis
- Trial name
- FAIR (NCT05155761)
- Testing
- FeetMe® Monitor
- Where
- France
- Volunteers
- 250 people
- Sponsor
- FeetMe
Proximal Humeral Fracture
A Research Study to Understand and Predict the Failure of Shoulder Fracture Fixations Using Computer Simulations
Fractures of the shoulder, the so-called proximal humeral fractures, can be treated with locking plates that have shown good results in clinical practice, but complications can occur.
- Trial name
- PHILOS-SIM (NCT04056351)
- Testing
- Post-Operative (OP) Computer Tomography (CT), Questionnaires on patient activity and comorbidities, Grip strength measurement
- Where
- 2 sites in Austria, Belgium
- Volunteers
- 29 people
- Sponsor
- AO Research Institute Davos
Fracture
Platelet Rich Plasma Injection in Pilon Fractures
Patients who sustain broken ankles have a very high risk of developing arthritis soon after injury (within 2 years). This arthritis can cause increased pain and a decrease level of function, especially if the injury occurs at an…
- Trial name
- NCT02481869
- Testing
- Arthrocentesis/PRP, Arthrocentesis/Saline
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Missouri-Columbia
Osteoporosis
Study and Follow-up of the Clinical Effectiveness and Comparative Safety of Biosimilar Teriparatide in the Management of Postmenopausal or Senile.
Non-interventional observational prospective follow-up study of cohorts of patients with Previous diagnosis of Osteoporosis with high risk of fractures, with/without previous fractures and treatment with bone formers (biosimilar…
- Trial name
- ESECTO (NCT05369013)
- Where
- 10 sites in Spain
- Volunteers
- 188 people
- Sponsor
- STADA, Spain
Healthcare; Risk Prediction; Diabetic Patients With Osteoporosis
A Model for Risk Prediction of Fracture in Diabetic Patients With Osteoporosis
The fracture risk of diabetic patients proves to be higher than those without diabetesdue to thehyperglycemia, usage of diabetes drugs, the changes in insulin levels and excretion, and this risk begins as early as…
- Trial name
- NCT04534166
- Testing
- Risk Prediction of Fracture in Diabetic Patients with Osteoporosis
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Type 2 Diabetes
Study to Weigh the Effect of Exercise Training on BONE (SWEET-BONE) Quality and Strength in Type 2 Diabetes
Type 2 diabetes mellitus (T2DM) is associated with increased fracture risk despite normal to increased bone mass, thus suggesting poor bone quality.
- Trial name
- SWEET-BONE (NCT02421393)
- Testing
- supervised exercise training
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Metabolic Fitness Association, Italy
Hip Fracture (First Incidence of)
Diet and Hip Fracture Risk in the United Kingdom Women's Cohort
Hip fracture is a common serious injury in older women that reduces quality of life and can lead to premature death. In the United Kingdom, hip fractures are estimated to account for 1.5 million hospital bed days used per year…
- Trial name
- NCT05081466
- Testing
- Dietary pattern, Fruit and vegetable intake, Meat intake
- Where
- United Kingdom
- Volunteers
- 35,372 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Type 2 Diabetes Mellitus and Fragility Fractures
A Prospective Cohort Study:Forecast Fracture Risk With a Serum Marker of Type 2 Diabetes in Guangzhou Community
The objective of this study is to find out the biochemical markers which have independent predictive value of fragility fractures risk with Type 2 diabetes in Guangzhou community and evaluate bone strength better and increase the…
- Trial name
- NCT03456271
- Where
- 5 sites in China
- Volunteers
- 99 people
- Sponsor
- Zhujiang Hospital
Pulmonary Disease, Chronic Obstructive, Osteoporosis
CT-Based Modeling of Bone Micro-Architecture and Fracture-Risk in COPD
The goal of this translational study is to establish a newly emerging CT-based tool for the characterization of changes in bone micro-architecture and assessment of their implications for fracture-risk in a population of COPD…
- Trial name
- NCT03534934
- Testing
- Vital signs, Urine Pregnancy Test, Questionnaires
- Where
- 2 sites in United States
- Volunteers
- 560 people, healthy volunteers welcome
- Sponsor
- Punam K Saha
AI (Artificial Intelligence), Osteoporosis
Evaluation of Dora Care for Supporting Fracture Liaison Services (FLS)
What is the study about? This study is testing "Dora", an AI-powered assistant that can make phone calls to patients, for use in the Fracture Liaison Service (FLS).
- Conditions
- AI (Artificial Intelligence), Osteoporosis, Outpatient, Telemedicine
- Trial name
- NCT07464171
- Testing
- Dora call
- Volunteers
- 217 people
- Sponsor
- Ufonia
Alcohol Use Disorder, Stress Reaction
Stress-related Predictor Profiles in Human Addiction
Long-term aim is the definition of a setup of mobile sensors and their integration in a mobile infrastructure that allows the prediction of stress related alcohol intake in an ambulatory setting.
- Conditions
- Alcohol Use Disorder, Stress Reaction, Social Stress, Craving
- Trial name
- NCT03810924
- Testing
- Trier Social Stress Test, Ergometer, Barlab-Exposure
- Where
- Germany
- Volunteers
- 121 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Spinal Fractures
Anterior Screw Fixation Versus Halo Immobilization of Type II Odontoid Fractures in Geriatric Patients With Increased Anesthesia Risk
The management of type II odontoid fractures in geriatric trauma victims remains a source of substantial controversy. The purpose of this study was to compare anterior screw fixation with halo-vest-immobilization in patients with…
- Trial name
- NCT02432495
- Testing
- ANTERIOR SCREW FIXATION, HALOV VEST IMMOBILIZATION
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Radius Fractures
Young Goalkeeper's Fracture: Radiographic Findings
The aim of this project is to evaluate retrospectively goalkeeper's fractures in children using the children fracture classification and to evaluate the distal radius tilt angle of the growth plate on plain radiographs of the…
- Trial name
- Goalkeeper (NCT02840188)
- Testing
- Radius tilt angle
- Where
- Switzerland
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Ankle Fractures:Osteosynthesis of High-Risk Ankle Fractures Using Locked Fibula Nails
Osteosynthesis of High-Risk Ankle Fractures Using Locked Fibula Nails: What Results for Which Patients?
Ankle fractures are among the most common injuries in orthopedic and trauma surgery, accounting for 9% of all fractures. They can be classified into isolated malleolar fractures (internal and/or external), pilon fractures, and…
- Trial name
- OFCCF (NCT06518265)
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Grenoble
Dementia, Motor Impairments
PERDOVE ANZIANI: a Prospective Cohort Study on Older Patients
This prospective observational cohort study aims at studying functional and clinical outcomes of patients (N = 329) admitted to 4 geriatric hospital facilities of the St John of God Order in Northern Italy during an index period…
- Conditions
- Dementia, Motor Impairments, Stroke, Thighbone Fractures
- Trial name
- NCT01699984
- Where
- 4 sites in Italy
- Volunteers
- 329 people
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Osteoporosis
Clinical Validation of BBCT-hip
The clinical study is aimed at assessing the accuracy of the in silico methodology BBCT-hip. BBCT-hip takes as inputs the subject-specific height and weight, and the CT scan of his femur to predict the risk of fracture for the…
- Trial name
- ValidaBBCT-hip (NCT06270758)
- Testing
- CT scan at the femur
- Where
- 2 sites in Italy
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Osteoporosis, Osteoporotic Fractures
An Assessment of Treatment Adherence of Osteoporosis Patients From a Biopsychosocial Perspective
This observational study aims to learn about the psychosocial risk factors of osteoporosis (OP) patients. The main question it aims to answer is: Which biopsychosocial factors affect OP patients' fragility fracture risk regarding…
- Conditions
- Osteoporosis, Osteoporotic Fractures, Psychosocial Functioning, Medication Adherence
- Trial name
- NCT05943600
- Where
- Turkey (Türkiye)
- Volunteers
- 585 people
- Sponsor
- Istanbul University
Vitamin D Deficiency, Stress Fracture
Vitamin D3 Supplementation and Stress Fracture Occurrence in High-Risk Collegiate Athletes
The main objective of this study is to find a correlation between vitamin D deficiency and stress fracture occurrences in athletes who participate in high-risk activities.
- Conditions
- Vitamin D Deficiency, Stress Fracture, Athletic Injuries, Orthopedic Disorder
- Trial name
- NCT03395171
- Testing
- Cholecalciferol (Vitamin D3)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Prisma Health-Midlands
Intercostal Nerve Injury
Evaluation of Intercostal Neuralgia in Patients With Chest Tube Insertion After Traumatic Rib Fracture
Traumatic rib fractures are common injuries following blunt chest trauma, often requiring chest tube insertion to manage complications such as pneumothorax or haemothorax.
- Trial name
- NCT07308587
- Testing
- Chest tube insertion
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Sunnybrook Health Sciences Centre