Clinical trials: Robotic Exoskeleton
Stroke, Hemiparesis
Human-Machine System for the H2 Lower Limb Exoskeleton
This research study will investigate the use of smart lower limb robotic exoskeleton (developed by the CSIC, Spain) in rehabilitation after stroke. It will compare robotic-assisted rehabilitation with supervised motor practice.
- Trial name
- H2-NeuroExo (NCT02114450)
- Testing
- Robot-assisted training with the H2 lower limb powered exoskeleton, Supervised motor practice
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Houston
Traumatic Spinal Cord Injury
Exoskeleton Training for Spinal Cord Injury Neuropathic Pain (ExSCIP)
The goal of this feasibility trial is to learn if exoskeleton or robotic walking works to reduce nerve (neuropathic) pain after spinal cord injury.
- Trial name
- ExSCIP (NCT06463418)
- Testing
- Ekoskeleton (Intervention), Relaxation (Comparator)
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- University College Dublin
Severe Stroke or Similar Neurological Muscle Weakness
Mobility Training Using Exoskeletons for Functional Recovery After Stroke
The purpose of this study is to assess the safety and effectiveness of the Ekso robotic exoskeleton in persons affected by a severe stroke.
- Trial name
- NCT02128152
- Testing
- Ekso exoskeleton
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Shirley Ryan AbilityLab
Chronic Stroke
Differential Effectiveness of Robotic Assisted Therapy on Upper Extremity Function in Patients With Chronic Stroke
The objectives of this study are to: determine the effects of exoskeleton vs. end effector training systems on upper extremity motor and physiological function, daily functions, quality of life and self-efficacy in patients with…
- Trial name
- NCT04260061
- Testing
- training systems
- Where
- Taiwan
- Sponsor
- Chang Gung Memorial Hospital
Ischemic Stroke, Acute
Innovative Technologies in Restoring Gait and Balance Funtions in Ischemic Stroke Patients at the Inpatient Stage
The scientific hypothesis was based on data on the effectiveness of the usage of robotic mechanotherapy and virtual reality technologies.
- Trial name
- NCT05423626
- Testing
- technologies of robotic mechanotherapy with FES, biofeedback virtual reality technologies
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- Moscow Scientific and Practical Center of Medical Rehabilitation, Restorative and Sports Medicine
Cerebral Palsy
Initial Outcomes of Robotic Lower Extremity Exoskeleton Use by a Non-ambulatory Child With CP
There are very few evidence-based interventions for children with cerebral palsy who cannot walk. The Trexo-Home is a device that is newly available for rent by families, but its impact is unknown.
- Trial name
- NCT04251390
- Testing
- trexo Home
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of Calgary
Neuromuscular Disorders, Neurodevelopmental Disorders
Efficacy and Usability of the EXPLORER Exoskeleton in Children With Neurodevelopmental Disorders in Natural Environments
Neurodevelopmental disorders often lead to abnormal development of the Central Nervous System (CNS), frequently causing motor dysfunctions such as an inability to stand and walk.
- Trial name
- NCT06765070
- Testing
- EXPLORER
- Where
- 6 sites in Spain
- Volunteers
- 15 people
- Sponsor
- MarsiBionics
ALS - Amyotrophic Lateral Sclerosis
Atalante Exoskeleton in the Rehabilitation of Patients With Amyotrophic Lateral Sclerosis
Using a MRI gait motor imagery paradigm in ALS patients in order to study how ALS affects the function of the central neural networks involved in gait function, we showed a reorganization of the motor networks that represents a…
- Trial name
- EXALS (NCT06199284)
- Testing
- Atalante exoskeleton
- Where
- 3 sites in France
- Volunteers
- 20 people
- Sponsor
- Institut de Recherche sur la Moelle épinière et l'Encéphale
Spinal Cord Injury
Examination of the Role of Human Exoskeletons in Rehabilitation
Background and Rationale: Traumatic spinal cord injury (SCI) affects approximately 12,400 individuals annually in the USA, predominantly impacting healthy young adults aged 20-40 years.
- Trial name
- REHA-EXO (NCT07669181)
- Testing
- Exoskeleton based gait therapy
- Where
- Hungary
- Volunteers
- 50 people
- Sponsor
- University of Pecs
Patients Post-cardiothoracic Surgery
Robotic Exoskeletons in Acute Care Therapy
The goal of this clinical trial is to establish the safety, feasibility, and preliminary findings of overground robotic exoskeleton early ambulation (ORE-EA) compared to usual care early ambulation (UC-EA) in the rehabilitation…
- Trial name
- REACT-CVTS (NCT07353892)
- Testing
- Overground robotic exoskeleton early ambulation (ORE-EA), Usual care early ambulation (UC-EA)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Baylor Research Institute
Stroke
SPiRE Maestro Hand Exoskeleton for Rehabilitation Post Stroke
The research team will develop a novel training tool to improve finger joint coordination, to address the unmet need in the current rehabilitation, thereby enhancing hand function and contributing to improved independence and…
- Trial name
- NCT04978467
- Testing
- Exoskeleton
- Where
- United States
- Sponsor
- VA Office of Research and Development
Stroke, Paresis
Exoskeleton-assisted Training to Accelerate Walking Recovery Early After Stroke: the TARGET Phase II Study
Phase II: Investigating the effects of additional robot-assisted gait training either initiated early (2 weeks post-stroke) or delayed (8 weeks post-stroke) after stroke onset.
- Conditions
- Stroke, Paresis, Gait, Hemiplegic
- Trial name
- TARGET (NCT03727919)
- Testing
- Exoskeleton-assisted gait training
- Where
- 3 sites in Belgium
- Volunteers
- 19 people
- Sponsor
- Universiteit Antwerpen
Hip Fracture, Geriatrics
Clinical Efficacy of Exoskeleton Robot-Assisted Rehabilitation on Lower Limb Functional Recovery in Elderly Patients With Hip Fracture
With the intensification of population aging, hip fracture, as a common bone disease, is seeing an increasing incidence rate among the elderly population.
- Conditions
- Hip Fracture, Geriatrics, Lower Extremity Dysfunction, Postoperative Rehabilitation
- Trial name
- NCT07323147
- Testing
- Exoskeleton, Conventional rehabilitation program
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Hai bao
Spinal Cord Injuries (SCI), Muscle Spasticity as a Result of Spinal Cord Injury
Powered Exoskeleton-Assisted Walking in Persons With Spinal Cord Injury
Spinal Cord Injury (SCI) represents a significant health challenge, particularly when it comes to the ability to walk. Among its many consequences, mobility impairment can not only directly impact quality of life but also cause a…
- Conditions
- Spinal Cord Injuries (SCI), Muscle Spasticity as a Result of Spinal Cord Injury, Rehabilitation, Exoskeleton Device
- Trial name
- EKSO-SCI (NCT07884591)
- Testing
- Wearable Powered Exoskeleton
- Where
- Italy
- Volunteers
- 74 people
- Sponsor
- IRCCS San Raffaele Roma
Stroke
Robot-Enhanced Stroke Therapy Optimizes Rehabilitation (RESTORE)
The purpose of this study is to investigate two aspects of robotic therapy after stroke. One goal is to determine if early robotic rehabilitation of the upper limb (beginning 5-9 days post-stroke) is more effective than later…
- Trial name
- RESTORE (NCT04201613)
- Testing
- Robotic exoskeleton, Usual Care
- Where
- Canada
- Volunteers
- 132 people
- Sponsor
- University of Calgary
CP (Cerebral Palsy), Robotic Exoskeleton
Study Aims to Compare the Effect of Robotic-assisted Gait Training and Conventional Treadmill Training on Postural Stability in Ambulatory Children With Cerebral Palsy.
The aim of this study is to explore the impact of gait training with a robotic device versus treadmill training on enhancing postural stability and walking capabilities in children with cerebral palsy (CP).
- Conditions
- CP (Cerebral Palsy), Robotic Exoskeleton, Treadmill Locomotor-based Training, Postural Stability
- Trial name
- NCT06719271
- Testing
- Participants this group will receive gait training in robotic assisted gait training (RAGT) three times per week for eight weeks, Body Weight Supported Treadmill Training
- Where
- Saudi Arabia
- Volunteers
- 36 people
- Sponsor
- King Saud University
Spinal Cord Injury
Non-Ambulatory SCI Walk Using a Robotic Exoskeleton: Effect on Bone and Muscle
The purpose of this research study is to evaluate an exoskeleton device and mobility skills in the device.
- Trial name
- NCT02324322
- Testing
- Exoskeleton Training, Muscle Biopsies, MRI
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Kessler Foundation
Spinal Cord Injury, Incomplete Spinal Cord Injury
Evaluation of Robotic Exoskeletons Therapy for Gait Rehabilitation in Patients With Incomplete Spinal Cord Injury.
The objective of the study is to assess the efficacy of the Exo-H2 robotic exoskeleton for walking rehabilitation of people with incomplete spinal cord injury.
- Trial name
- NCT03477123
- Testing
- Walking therapy with Exo-H2 exoskeleton
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Hospital Nacional de Parapléjicos de Toledo
Hemiparesis/Hemiplegia (One Sided Weakness/Paralysis)
Effects of Unilateral Robotic Assistance on Compensation Strategies and Muscular Activity During Hemiparetic Gait
Hemiparetic gait is characterized by strong asymmetries that could severely affect the quality of life of stroke survivors. This asymmetry is due to motor deficits in the paretic leg and the resulting compensations in the…
- Trial name
- NCT05138211
- Testing
- Exoskeleton assisted gait on a treadmill
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Spanish National Research Council
Robotic Exoskeleton, Post-acute Covid-19 Syndrome
Robotic Assisted Hand Rehabilitation Outcomes in Adults After COVID-19
Prolonged hospitalization in severe COVID-19 cases can lead to substantial muscle loss and functional deterioration. While rehabilitation is vital, conventional approaches encounter capacity constraints.
- Conditions
- Robotic Exoskeleton, Post-acute Covid-19 Syndrome, Rehabilitation Outcome, Physical And Rehabilitation Medicine
- Trial name
- NCT06137716
- Testing
- Training with a Robotic Hand Exoskeleton
- Where
- Spain
- Volunteers
- 13 people
- Sponsor
- University of Valladolid