Clinical trials: Rocuronium
Anesthesia Recovery
"Low Dose Sugammadex Combined With Neostigmine and Glycopyrrolate Versus Full Dose Sugammadex for Reversal of Rocuronium-induced Neuromuscular Blockade: a Cost Saving Strategy"
Prospective Randomized non inferiority Trial involving adult patients undergoing elective surgery under general anesthesia.56 Patients will be enrolled in 2 groups : full dose sugammadex vs half dose sugammadex for reversal of…
- Trial name
- NCT02375217
- Testing
- Sugammadex, Neostigmine, glycopyrrolate
- Where
- Lebanon
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Neuromuscular Block, Residual
Diaphragm Function After Reversal of Rocuronium-induced Neuromuscular Blockade With Sugammadex or Neostigmine in Children
This study is to evaluate the recovery of diaphragm function and atelectasis after reversal of neuromuscular blockade with Neostigmine and Sugammadex using lung ultrasound and diaphragm ultrasound for children aged 2 to 7 who are…
- Trial name
- NCT05724550
- Testing
- Sugammadex, Neostigmine
- Where
- South Korea
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Rocuronium, Muscle Weakness
General Anesthesia With and Without Muscle Relaxation and Muscle Strength Recovery
Neuromuscular blocking agents are often used during general anesthesia. Also, general anesthesia may be performed without use of neuromuscular blocking agents.
- Conditions
- Rocuronium, Muscle Weakness, General Anaesthesia
- Trial name
- NCT04760912
- Testing
- Rocuronium, General anesthesia for surgery
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinical Hospital Centre Zagreb
Chronic Otitis Media, Anesthesia
Optimal Dose of Combination of Rocuronium and Cisatracurium
BACKGROUND: The combinations of rocuronium and cisatracurium have a synergic effect. The investigators studied whether the prediction is possible to have a sufficient effect of reducing the dose when combining the two…
- Trial name
- CRC (NCT02495038)
- Testing
- 10% reduction of combination of Esmeron® and Nimbex®, 20% reduction of combination of Esmeron® and Nimbex®
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Intubating Conditions, Postoperative Myalgia
Comparing Intubating Conditions Using Succinylcholine or Rocuronium for Rigid Bronchoscopy
Succinylcholine is commonly used for neuromuscular relaxation for short procedures such as rigid bronchoscopy. A more modern alternative is the application aof rocuronium, reversed by sugammadex.
- Conditions
- Intubating Conditions, Postoperative Myalgia, Patient Satisfaction
- Trial name
- NCT01996358
- Testing
- Succinylcholine, Rocuronium 0,3, Rocuronium 0,6
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Dr. Horst Schmidt Klinik GmbH
Muscle Relaxants
The Effect of no Muscle Relaxant Versus Reduced-dose Rocuronium on Anesthesia in Adenotonsillectomy
This study aimed to compare the effect of no muscle relaxants and reduced-dose rocuronium on the anesthetic induction and emergence with fentanyl in children undergoing adenotonsillectomy.
- Trial name
- NCT02467595
- Testing
- Rocuronium bromide 0.15 mg kg-1, Rocuronium bromide 0.3 mg kg-1, Fentanyl
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Korea University Anam Hospital
Gynecological Disorder
Timing of Rocuronium After Induction With Propofol on Temporal Summation of Pain
Temporal summation of pain, which is defined as the perception of increasingly greater pain evoked by repetitive painful stimuli, is highly variable between individuals.
- Trial name
- NCT04547608
- Testing
- The difference of the timing of rocuronium administration after propofol injection
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Rocuronium Adverse Reaction, Lidocaine Adverse Reaction
Effects of Pretreatment With Different Doses of Lidocaine on Injection Pain
One of the medications administered to patients in general anesthesia practice is rocuronium, which causes pain during intravenous administration.
- Trial name
- NCT06865300
- Testing
- Lidocain 40 mg, lidocain 1 mg/kg, serum physiologic
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Giresun University
Magnesium Sulfate, Neuromuscular Blockade
Effect of Pre-treatment With Magnesium Sulfate on the Duration of Deep Neuromuscular Blockade With Rocuronium
It is a prospective, comparative, randomized, double-blind clinical trial whose hypothesis is that pre-treatment with magnesium sulfate, due to its action at the neuromuscular junction,potentiate the duration of deep…
- Conditions
- Magnesium Sulfate, Neuromuscular Blockade, Rocuronium, Deep Neuromuscular Blockade
- Trial name
- NCT02989272
- Testing
- Sulfate, Magnesium, saline group
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Federal de Bonsucesso
Anesthesia
The Neuromuscular Effect of Rocuronium in Patient
Rocuronium block neuromuscular transmission at the neuromuscular junction, causing paralysis of the affected skeletal muscles. There have been several studies reported positive relationship between muscle mass and amount of…
- Trial name
- NCT02657187
- Testing
- Inbody, Rocuronium
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Go Eun Bae
Neuromuscular Blockade
Comparison of Neuromuscular Recovery at the Hand and Foot
Gold standard for neuromuscular blockade evaluation is accelerometry in three dimensions at the thumb. There are many times that measurement at the hand can be falsely under-estimated intraoperatively secondary to constriction of…
- Trial name
- NCT06236763
- Testing
- TOFscan foot
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Rocuronium, Injection Pain
Median Effective Dose of Remifentanil for the Prevention of Pain Caused by the Injection of Rocuronium
As a medium-and long-term non-depolarizing muscle relaxant, rocuronium has the advantages of quick effect, no histamine release and accumulation and no obvious cardiovascular adverse reactions, so it has been widely used in…
- Trial name
- NCT05217238
- Testing
- Remifentanil
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Yangzhou University
Body Weight Changes, Rocuronium
Lean Body Weight-adjusted Rocuronium Dose and Intubation Conditions
In this study, researchers wiil administer rocuronium, based on either the lean body weight or the total body weight in patients with body mass index (BMI) of 18.5 to 34.9 and compared the duration of action of the drug and its…
- Conditions
- Body Weight Changes, Rocuronium, Intubation Conditions
- Trial name
- LBW (NCT05476952)
- Testing
- he patients who are administered rocuronium according to LBW were categorized as "LBW", and The group number for those administer according to TBW was categorized as "K".
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- DUYGU DEMİROZ
Pain, Withdrawal
Evaluation of the Effect of Venous Diameter Measurement by Ultrasonography on Pain and Withdrawal Response
During general anesthesia, intravenous (IV) medications can disrupt the patient's comfort by causing a pain sensation or a withdrawal response in the heart.
- Trial name
- VDIAMETER (NCT03376308)
- Testing
- Pain Score, Withdrawal movement score, hemodynamic response
- Where
- Turkey (Türkiye)
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Injection Pain
Effect of TEAS on Rocuronium Injection Pain
Pain from the injection of rocuronium is a common side effect during anesthetic practice, occurring in 50%-80% of patients. Several methods have been used to reduce this pain.
- Trial name
- NCT04943367
- Testing
- TEAS
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Konya Meram State Hospital
Neuromuscular Blockade
Reversal of Neuromuscular Blockade During the General Anaesthesia
There are individual reports indicating that after the reversal of nondepolarizing neuromuscular blockade with neostigmine, some patients starts to relax spontaneously again after the tof ratio has already recovered to the safe…
- Trial name
- NCT04048655
- Testing
- Neostigmine, Combinations
- Where
- Finland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tampere University Hospital
Magnesium Sulfate Causing Adverse Effects in Therapeutic Use, Neuromuscular Blockade
Effect of Magnesium on Dose of Rocuronium for Deep Neuromuscular Blockade
It is well known that magnesium enhances the effect of neuromuscular blocking agents such as rocuronium. However, it is not known how much magnesium can reduce neuromuscular blocking agents in maintaining deep neuromuscular…
- Trial name
- NCT04013243
- Testing
- Magnesium Sulfate
- Where
- South Korea
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Neuromuscular Block
The Influence of Intravenous Lidocaine on the Action of the Neuromuscular Blocker Rocuronium
Lidocaine is a local anesthetic which is widely used in daily anesthesia and surgical practice. It has been shown that intravenous lidocaine given during an operation has analgesic properties.
- Trial name
- LidoRoc (NCT00828373)
- Testing
- Lidocaine
- Where
- Switzerland
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Bariatric Surgery
Determinants on Rocuronium Dose for Deep Block in Bariatric Surgery
Find out the deciding factor(total body weight, corrected body weight, ideal body weight, fat-free mass, body mass index, skeletal muscle mass, body fat) of neuromuscular blocker dose for deep neuromuscular blockade in bariatric…
- Trial name
- NCT04709406
- Testing
- deep neuromuscular blockade in bariatric surgery
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
General Anesthesia, Elective Surgery
Effect of Pre-injection of Rocuronium on Neuromuscular Blockade Onset Time and Hemodynamics During General Anesthesia Induction
This is a single-center, prospective, randomized, controlled trial comparing pre-injection versus standard bolus administration of rocuronium bromide for general anesthesia induction.
- Trial name
- NCT07716891
- Testing
- Rocuronium Bromide (Pretreatment Injection), Rocuronium Bromide (Conventional Injection)
- Where
- China
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- General Hospital of Ningxia Medical University