Clinical trials: Root Canal
Root Canal Infection
One-visit Root Canal Treatment Using Chlorhexidine as a Final Irrigant
A hundred asymptomatic molar teeth with periapical lesions were treated in single versus multiple visit root canal treatment. Half of the teeth were randomly assigned to the one-visit (OV) group and received an additional final…
- Trial name
- NCT05006209
- Testing
- One visit root canal treatment, Two visit root canal treatment
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ege University
Anesthesia
Effect of Simple Simulator-based Training on Initial Performance of Novices Iultrasound-guided Adductor Canal Block
This prospective descriptive study is effect of simple simulator-based training on initial performance of novices in ultrasound-guided adductor canal block.
- Trial name
- NCT06476652
- Where
- Thailand
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University
Pain, Postoperative, Total Knee Arthroplasty (TKA)
Continuous Adductor Canal Blocks Vs. Low Dose Femoral Nerve Blocks For Early Rehabilitation After Total Knee Arthroplasty
Recently, several articles have suggested or reported that Adductor Canal Blocks (ACBs) offer adequate or equal analgesia and may promote better performance in early rehabilitation following Total Knee Arthroplasty (TKA) when…
- Trial name
- FemVsACB (NCT02453321)
- Testing
- Continuous Femoral Nerve Block, Nerve Block, Continuous Adductor Canal, Continuous Sciatic Nerve Block
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Kevin King, DO
Necrotic Pulp
Rosmarinus Officinalis Versus 2.5%Sodium Hypochlorite as Root Canal Irrigants
To measure the Effect of Rosmarinus Officinalis versus 2.5%Sodium Hypochlorite as Root canal Irrigants on the Intensity of post-operative pain and Bacterial Reduction in asymptomatic necrotic Mandibular premolars.
- Trial name
- NCT05289843
- Testing
- Rosmarinus Officinallis
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Immunization, Human Influenza
Study of Yili Mei Yi Tian Active Lactobacillus Drink to Improve Immunity and Digestive System
Study on Evaluating the Promote Effect of Yili Mei Yi Tian Active Lactobacillus Drink on Immunity and Physical Intestinal Canal
- Conditions
- Immunization, Human Influenza, Common Cold, Constipation
- Trial name
- NCT01677715
- Testing
- Yili "Mei Yi Tian" active lactobacillus drink, recombined milk drink contains no lactobacillus
- Where
- 2 sites in China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Inner Mongolia Yili Industrial Group Co., Ltd
Root Canal Treatment, Endodontic Disease
Endodontic Root-canal Treatments Evaluated After Long-term Time
The aim of the study was to evaluate the root canal treatments performed from 1989 to 1995. Type of complication, success, new endodontic diseases and number of success were reported.
- Trial name
- ENDOBO20 (NCT03215225)
- Testing
- Root canal orthograde treatment
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Apical Periodontitis
Clinical and Radiographic Success of Regeneration Using Injectable Platelet Rich Fibrin
Study aimed at assessing the clinical and radiographic success of pulp regeneration using injectable platelet-rich fibrin in mature permanent molars with apical periodontitis versus root canal treatment using Gutta Percha (GP)…
- Trial name
- NCT06086249
- Testing
- Regeneration using Injectable platelet-rich fibrin, Root canal treatment
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Muscle Strength, Healthy Volunteers
Adductor Canal Block and Effect of 10 Versus 30 ml Ropivacaine on Muscle Strength: a Randomized Study in Healthy Volunteers
To investigate whether reducing the volume (30 versus 10 ml) ropivacaine injected can reduce the number of subjects with impaired muscle strength following adductor canal block.
- Trial name
- NCT01981746
- Testing
- Adductor canal block with ropivacaine 0.1%
- Where
- Denmark
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Anesthesia, Stress, Physiological
Adductor Canal Block Versus Patient Controlled Analgesia, in the Surgical Stress Response for Anterior Cruciate Ligament Repair
To evaluate the surgical stress response in anterior cruciate ligament repair with an adductor canal block versus patient controlled endovenous analgesia.
- Conditions
- Anesthesia, Stress, Physiological, Surgery
- Trial name
- NCT04797546
- Testing
- Adductor Canal Block, Morphine Patient Controlled Analgesia
- Where
- Chile
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Inferior Alveolar Nerve Injuries, Root Canal Treatment
The Need Of Root Canal Treatment After Coronectomy In Mandibular Third Molars
The study included 24 patients with written and verbal consent Results with close proximity to IAN diagnosed based on radiographs and evaluation on the criteria of Howe, and Poyton were selected and divided into two groups by…
- Conditions
- Inferior Alveolar Nerve Injuries, Root Canal Treatment, Paresthesia, Third Molar
- Trial name
- NCT05744882
- Testing
- coronectony, root canal treatment
- Where
- Pakistan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Altamash Institute of Dental Medicine
Detecting Number of Root Canal of Human Mandibular Second Molar
Accuracy of Artificial Intelligence Technology in Detecting Number of Root Canal of Human Mandibular Second Molar: Diagnostic Accuracy Experimental Study
to detect the Accuracy of Artificial Intelligence Technology in Detecting Number of Root Canal of Human Mandibular Second Molar: Diagnostic Accuracy Experimental Study.
- Trial name
- AI (NCT07319221)
- Testing
- AI, CBCT
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Osteo Arthritis Knee
Efficacy of Ipack Block and Surgeon's Joint Infiltration in Total Knee Arthroplasty
Total knee arthroplasty(TKA) is an effective modality for the treatment of advanced osteoarthritis of the knee joint with excellent outcomes.
- Trial name
- NCT03653416
- Testing
- Ipack, Bupivacaine, Peri Articular Infiltration
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Knee Surgeries, Total Ankle Arthroplasty
Adductor Canal Block With IPACK Versus 4-in-1 Block for Postoperative Analgesia in Knee Surgery
This randomized interventional study compares the analgesic efficacy of Adductor Canal Block combined with Infiltration of the Posterior Capsule of the Knee (IPCAK) versus the 4-in-1 block technique in patients undergoing knee…
- Conditions
- Knee Surgeries, Total Ankle Arthroplasty, Anterior Cruciate Ligament (ACL) Tear, Posterior Cruciate Ligament Tear
- Trial name
- NCT07700797
- Testing
- Adductor canal block with IPACK, 4 in 1 block
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Dental Caries, Pulp Necrosis
Moringa Oleifera vs Sodium Hypochlorite for Root Canal Irrigation in Nonvital Primary Molars
This randomized clinical trial aims to evaluate and compare the antimicrobial efficacy of Moringa Oleifera leaf extract versus sodium hypochlorite as root canal irrigants in pulpectomy of nonvital primary molars in pediatric…
- Conditions
- Dental Caries, Pulp Necrosis, Primary Tooth Pulpectomy, Pediatric Dentistry
- Trial name
- MORvNAOCL (NCT06971055)
- Testing
- Sodium hypochlorite, Moringa Oleifera Leaf Extract
- Where
- Egypt
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Cairo University
ACL Tear, Opioid Misuse
Exparel vs. ACB With Bupivacaine for ACL Reconstruction
Opioid misuse and addiction among children and adolescents is an increasingly concerning problem. Post-surgical opioid prescriptions for commonly performed surgeries such as anterior cruciate ligament reconstruction (ACLR)…
- Conditions
- ACL Tear, Opioid Misuse, Pain, Anxiety
- Trial name
- NCT06274008
- Testing
- Exparel
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Orange County
Necrotic Pulp
Incidence of Post-Operative Pain After Single Visit Root Canal Treatment in Necrotic Teeth Using Two Different Rotary Systems (Protaper Nex t& Neolix File)
this prospective in vivo randomized clinical is to evaluate the post operative pain (incidence ,degree and duration) with multiple full rotation file (protaper next ®) and single full rotation file (Neolix®) in treating maxillary…
- Trial name
- NCT03059290
- Testing
- neolix file
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Retreatment, Asymptomatic Apical Periodontitis
Effects of Irrigation Activation Systems on Postoperative Pain and Lesion Healing in Single-Visit Retreatment
In this superiority randomized clinical trial with a parallel design, 75 asymptomatic maxillary anterior teeth with 2-5 mm periapical lesions and a history of primary root canal treatment (PRCT) at least four years earlier were…
- Trial name
- NCT07150585
- Testing
- Ultrasonic Activation Group, Sonic Activation Group, Laser Activation Group
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ege University
Root Canal
Clinical Evaluation of Working Length Determination by Electronic Apex-Locator or Radiography on Adequacy of Final Working Length
Accurate length determination of root canal is essential in root canal therapy. Radiography has been the conventional method for this measurement but recently several in-vitro studies have shown that new generations of Electronic…
- Trial name
- NCT00901810
- Testing
- Electronic Apex Locator, Dental Radiography
- Where
- Iran
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Shiraz University of Medical Sciences
Prolonged Second Stage of Labor
Use of Lubricant Gel to Shorten the Second Stage of Labor During Vaginal Delivery
This experimental study aims to evaluate whether the application of obstetric lubricant gel during vaginal delivery can significantly reduce the duration of the second stage of labor, preserve perineal integrity, and decrease the…
- Trial name
- OBY-GEL (NCT07428317)
- Testing
- Obstetric Lubricant Gel, Standard Active Management of Second Stage
- Where
- Honduras
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Honduras
IVF
Uterine Lesions and Their Association to Invitro Fertilization(IVF) or Intracytoplasmic Sperm Injection(ICSI) Outcome
1. To study the effect of uterine wall , intracavitary , cervical as well as cervical canal lesion on the outcome of IVF/ICSI cycle. 2. To establish a score for prediction of IVF/ICSI cycle success .
- Trial name
- NCT04939376
- Testing
- IVF
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Assiut University