Clinical trials: Root Canal Sealers
Chronic Apical Periodontitis
In Vivo Study on the Material Properties of iRoot SP and nRoot SP Root Canal Sealers
A randomized controlled trial was conducted to compare the treatment efficacy of iRoot SP and nRoot SP Root Canal Sealer Materials in patients with chronic apical periodontitis.
- Trial name
- NCT07388901
- Testing
- iRoot SP, nRoot SP
- Where
- China
- Volunteers
- 160 people
- Sponsor
- The Dental Hospital of Zhejiang University School of Medicine
Asymptomatic Apical Periodontitis
Comparison of the Effects of Bio Ceramic and Epoxy Resin-based Sealers on Postoperative Pain After Root Canal Treatment
This study aims to compare the effect of bio ceramic sealer and resin-based sealer on the intensity and occurrence of post operative pain in single rooted teeth with asymptomatic apical periodontitis.
- Trial name
- NCT06543004
- Testing
- AH plus sealer, Bioceramic sealer
- Where
- Qatar
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Primary Health Care Corporation, Qatar
Root Canal Obturation
Endodontic Post-operative Pain Evaluation of Patients After Using Endomethasone N or Endomethasone SP (EndoPOP)
The study is a post-marketing performance and safety study, designed as a comparative, prospective, multicenter, simple-blind, randomized clinical trial.
- Trial name
- EndoPOP (NCT04885686)
- Testing
- Endomethasone N RCS, Endomethasone SP RCS
- Where
- 15 sites in France
- Volunteers
- 300 people
- Sponsor
- Septodont
Single-visit, Periapical Periodontitis
Postoperative Pain and Success of Single-Visit Root Canal Treatment Using Different Root Canal Sealers in Asymptomatic Teeth
This study evaluates the postoperative pain and long-term clinical and radiographic success of single-visit primary root canal treatment in asymptomatic teeth with periapical lesions.
- Trial name
- NCT07868315
- Testing
- One-Fill, TotalFill, AH Plus + Single Cone
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Istanbul Medipol University Hospital
Calcium Silicate Based Sealer (CSBS)
Efficiency of Calcium Hydroxide and Calcium Silicate-Based Sealers in Maxillary and Mandibular Molars on Post-Root Canal Pain
patients reported at department of Operative dentistry diagnosis section , patients coming to operative department of DIDC-DUHS with the chief complain of moderate to severe pain will be assessed .Complete history of each patient…
- Trial name
- CBSS (NCT07865429)
- Testing
- Calcium silicate based sealer
- Where
- Pakistan
- Volunteers
- 96 people
- Sponsor
- Dow University of Health Sciences
Asymptomatic Apical Periodontitis
Evaluation of Postoperative Pain After Using Resin-Based and Bioceramic Sealers in Mandibular Molars With Asymptomatic Apical Periodontitis
This study aims to evaluate the effect of two different root canal sealers-BioRoot RCS (a bioceramic-based sealer) and AH Plus (a resin-based sealer)-on postoperative pain following single-visit root canal treatment in mandibular…
- Trial name
- NCT07289633
- Testing
- BioRoot RCS, AH Plus
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- AZİZ ŞAHİN ERDOĞAN
Asymptomatic Vital Mandibular Molar Teeth
The Effect of Two Different Root Canal Sealers on Postobturation Pain and Clinical and Radiographical Outcome After Two-year Follow-up
Post-obturation pain evaluation(Part 1): One hundred asymptomatic mandibular molar teeth with vital pulp were randomly assigned into two groups according to the sealer used MTA Fillapex (Angelus Odontologica Industries SA…
- Trial name
- NCT05266599
- Testing
- MTA Fillapex root canal sealer, AH Plus root canal sealer
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ege University
Root Canal Obturation
Root Canal Obturation With a Ready-to-use Root Canal Sealer (PA1704) Versus BioRoot™ RCS: a Randomized Controlled Trial
The study design is a multicentric randomized controlled non-inferiority trial. 160 subjects (teeth) requiring a primary or a secondary root canal treatment will be enrolled in 2 groups (80 in each group).
- Trial name
- OPTIFILL (NCT04757753)
- Testing
- ready-to-use root canal sealer: PA1704, root canal sealer: BioRoot™ RCS
- Where
- 5 sites in Belgium, France
- Volunteers
- 160 people
- Sponsor
- Septodont
Post Operative Pain, Root Canal Sealers
The Incidence of Postoperative Pain After Using Different Types of Sealers
The aim of this randomized clinical trial is to evaluate and compare the incidence and intensity of post-operative pain after obturation using resin and silicon-based sealers.
- Conditions
- Post Operative Pain, Root Canal Sealers, Sillicon Based Sealers, Resin Based Sealers
- Trial name
- NCT05841290
- Testing
- Primary local anesthesia, Supplemental local anesthesia, Removal Of Caries and Access Cavity
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Endodontic Disease, Endodontically Treated Teeth
Outcome of Endodontic Treatment and Retreatment With a Bioceramic Sealer
This study is a prospective randomized controlled study of patients who come to the University. The aim is to evaluate the success rate of treatment and retreatment of canals using BioRoot ™ RCS cement compared with AH Plus up to…
- Trial name
- NCT04528979
- Testing
- BioRoot RCS® root canal sealer, AH Plus® root canal sealer
- Where
- Spain
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Juan Gonzalo Olivieri
Endodontic Disease
Treatment Outcome of Ortho MTA (BioMTA®) Cement vs AH Plus® Bioceramic Sealer (Dentsply).
The use of bioceramics materials as root canal fillings in endodontics is gaining traction due to their excellent biocompatibility, antibacterial and sealing abilities.
- Trial name
- NCT05984940
- Testing
- Ortho MTA cement, GP and AH Plus sealer
- Where
- Singapore
- Volunteers
- 70 people
- Sponsor
- National University Hospital, Singapore
Pulpitis - Irreversible, Pain, Postoperative
Comparison of Calcium Silicate-based Sealer and Epoxy Resin-based Sealer
Background: Sealers have been concerned with obturation. However, studies for assessing the effectiveness of endodontic treatment of sealer based on Calcium Silicate have been not much.
- Trial name
- NCT05904184
- Testing
- Epoxy resin-based sealers (ERS), Calcium silicate-based sealers (CSS)
- Where
- Vietnam
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Asymptomatic Apical Periodontitis, Root Canal Retreatment
Non-Surgical Single Visit Endodontic Retreatment in Cases With Asymptomatic Apical Periodontitis Using Bioceramic Sealer
The goal of this clinical trial is to learn if using bioceramic sealers in non surgical single visit endodontic retreatment in patients with endodontic treatment failure and asymptomatic apical periodontitis will work in…
- Trial name
- NCT06973135
- Testing
- Bioceramic sealer root canal obturation, resin sealer root canal obturation
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Saly Nazeer
Endodontic Disease
Evaluation of Antimicrobial Efficacy and Adaptability of Bioceramic Sealer Containing Nanoparticles
Successful endodontic treatment depends primarily on the elimination of infecting microorganisms. This is done by chemo-mechanical preparation of root canals, which is not enough and microorganisms might still survive.
- Trial name
- NCT04481945
- Testing
- bioceramic sealer
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Misr International University
Root Canal Obturation
Pain After Root Canal Obturation With Sealer Containing or Not 1% Enoxolone
This study aims to assess the efficacy of a zinc oxide eugenol sealer containing Enoxolone, a non-steroidal anti inflammatory drug (NSAID) on the pain relief after endodontic treatment.
- Trial name
- NCT03874949
- Testing
- SEALITE Regular, SEALITE Ultra
- Where
- France
- Volunteers
- 95 people
- Sponsor
- ACTEON Group
Oxidative Stress, Chronic Apical Periodontitis
Effect of Different Root Canal Sealers on Oxidative Stress Markers
The goal of this clinical trial is to primary purpose investigate and compare oxidative stress markers in patients with chronic apical periodontitis treated with different root canal paste in a single session.
- Trial name
- NCT07059481
- Testing
- Root Canal Treatment and Sample Collection, PAI Score Comparasion
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- bengi gülgü
Dental Pulp Necrosis
The Effect of Sealer Type and Obturation Technique on Postoperative Pain
Postoperative pain is an important consideration in endodontic treatment, and its incidence may be influenced by both obturation technique and sealer type.
- Trial name
- pain (NCT07386197)
- Testing
- Obturation of root canals
- Where
- Jordan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Apical Periodontitis
Comparison of AH Plus and WellRootST Root Canal Sealers in Terms of Postoperative Pain: One-Month Follow-up
This randomized, parallel-group clinical trial aimed to compare the effects of two root canal sealers, AH Plus and Well-Root ST, on postoperative pain in patients undergoing single-visit root canal treatment for teeth diagnosed…
- Trial name
- NCT07246174
- Testing
- AH Plus Root Canal Sealer, Well-Root ST Root Canal Sealer
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Medipol University
Symptomatic Irreversible Pulpitis
Postoperative Pain After Root Canal Obturation Using Bioceramic and Calcium Hydroxide Sealers
This study is designed to find out how different root canal sealers affect pain after root canal treatment. We are comparing two types of dental sealers: bioceramic sealer and calcium hydroxide sealer.
- Trial name
- BCvsCaOH (NCT07410780)
- Testing
- CeraSeal Bioceramic Sealer, Sealapex Calcium Hydroxide Sealer
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- HITEC-Institute of Medical Sciences
Endodontically Treated Teeth
Outcome of Root Canal Treatments Obturated With Calcium Silicate Based Sealers
The clinical use of a flowable premixed calcium-silicate bioceramic sealer used in association with warm carrier-based/single-cone technique will be compared with epoxy resin-based sealer with carrier-based technique.
- Trial name
- NCT05376033
- Testing
- root canal filling with Ceraseal sealer
- Where
- Italy
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University of Bologna