Clinical trials: Root Planing
Chronic Periodontitis
Burs Versus Curettes in Root Planing.
This study compares the efficacy of diamond burs and Gracey curettes in non-surgical periodontal treatment of chronic periodontitis by clinical, microbiological, biochemical parameters and scanning electron microscopic…
- Trial name
- NCT02875470
- Testing
- Intensiv Perio Set, Gracey curette
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Ege University
Periodontitis, Clindamycin Gel
Comparing Aloe Vera Gel and Clindamycin Gel Added to Scaling and Root Planing for Periodontitis
Periodontitis is an inflammatory disease affecting the tissues that support the teeth. Scaling and root planing is a standard nonsurgical treatment, but additional local treatments may help improve clinical periodontal outcomes…
- Conditions
- Periodontitis, Clindamycin Gel, Aloe Vera Gel, Scaling and Root Planing
- Trial name
- NCT07900802
- Testing
- Scaling and Root Planing
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Periodontitis, Chronic
Adjunctive Hydrogen Peroxide for Periodontal Therapy
There have been many adjunctive treatments for the additional clinical benefits to scaling and root planing (SRP) in the treatment of chronic periodontitis.
- Trial name
- AHP (NCT03262701)
- Testing
- Hydrogen Peroxide Gel, 13 weeks, Hydrogen Peroxide Gel, 26 weeks, Scaling and Root planing group
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Chronic Periodontitis (CP) Subjects.
"Effect of Scaling and Root Planing on Liver Function Test (Alanine Aminotransferase and Aspartate Aminotransferase) in Systemically Healthy - Chronic Periodontitis Subjects: a Clinical Trial."
Aim: To evaluate effect of non- surgical periodontal therapy on liver function in systemically healthy chronic periodontitis (CP) subjects.
- Trial name
- NCT02583841
- Testing
- Scaling and root planing
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
Periodontitis, Aggressive, Periodontal Diseases
Efficacy of GBT vs SRP+US, in the Treatment of Severe Generalized Periodontitis.
The first step in the management of periodontal disease involves the non-surgical removal of the soft and hard bacterial deposits at all supra- and sub-gingival sites, especially into deep pockets, which can be carried on with…
- Conditions
- Periodontitis, Aggressive, Periodontal Diseases, Periodontitis
- Trial name
- ERISRP (NCT05112471)
- Testing
- Airflow, Perioflow and Erythritol powder and ultrasonic debridement, Ultrasonic debridement and curettes
- Where
- Italy
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Periodontitis
A Phase I/II Study to Evaluate the Safety and Efficacy of PerioSept® as Adjunct to SRP in Subjects With Periodontitis
A Pharmacokinetic Pilot followed by a Phase I/II, Blinded, Randomized, Controlled, Parallel Arm Trial to Evaluate the Safety, Tolerability and Efficacy of PerioSept® and Scaling and Root Planing in Subjects with Periodontitis
- Trial name
- NCT02313883
- Testing
- PerioSept(r)
- Where
- 4 sites in United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Geistlich Pharma AG
Amoxicillin, Metronidazole
Alternative Antibiotic Regimen in Periodontitis Treatment
Context and Aims: Several studies have demonstrated an association between obesity, periodontitis, and exercise. This study aimed to investigate the effects of regular exercise on obese women with periodontal disease, using…
- Conditions
- Amoxicillin, Metronidazole, Ofloxacin, Periodontitis
- Trial name
- NCT04353362
- Testing
- Ofloxacin, Amoxicillin, Metronidazole
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Chronic Periodontitis, Type 2 Diabetes Mellitus
Effect of Non-surgical Periodontal Treatment on HbA1c in Type 2 Diabetic Patients
The main objective is to evaluate the effect of nonsurgical periodontal treatment on serum levels of HbA1c in patients with type 2 diabetes mellitus (T2DM).
- Trial name
- NCT02652026
- Testing
- Nonsurgical periodontal treatment, Dental Prophylaxis
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Periodontitis
Impact of SRP on Bone Resorption and Systemic Inflammatory Markers in Postmenopausal Women With Periodontitis
This study is designed to determine the effect of treating postmenopausal women and using non-surgical techniques on biomarkers of systemic inflammation (IL-6 ) and systemic bone resorption (C-terminal collagen cross-links, CTX).
- Trial name
- NCT04261491
- Testing
- scaling and root planing
- Where
- 2 sites in India
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periodontitis Stage III
Clinical and Laboratory Evaluation of Resveratrol Loaded Nanoparticles in the Treatment of Periodontitis: A Randomized Controlled Clinical Trial
The Aim of this study is to test the effectiveness of locally applied resveratrol as an adjunct to scaling and root planing in the treatment of periodontitis (primary outcome) .
- Trial name
- NCT07397026
- Testing
- Resveratrol loaded gel
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hagar Ahmed Ali Mohammed Elzain
Chronic Periodontitis, Generalized, Moderate
Er:YAG Laser Treatment of Moderate Chronic Periodontitis
The Er:YAG laser possesses specific characteristics allowing to be used in non-surgical periodontal treatment. The aim of the resent study was to evaluate the long-term clinical effectiveness of Er:YAG laser monotherapy in the…
- Trial name
- NCT05217823
- Testing
- Er:YAG laser, hand instruments
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Plovdiv Medical University
Halitosis
Efficacy of Glycine Powder Air-Polishing Combined With Scaling and Root Planing in the Treatment of Periodontitis and Halitosis
The aim of this clinical study was to evaluate the clinical efficacy of using perio flow adjunctively with mechanical instrumentation on periodontal parameters and halitosis.
- Trial name
- NCT03031756
- Testing
- glycine powder air-polishing (Air-Flows)Perio Powder, ultrasonic (Piezon Master 700; EMS, Nyon, Switzerland)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Near East University, Turkey
Chronic Periodontitis
Probiotics Effects to Initial Periodontal Treatment
The aim of this study is to evaluate the clinical and microbiological effects of Bifidobacterium animalis subsp. lactis DN-173010 containing yoghurt as an adjunct to mechanical periodontal treatment.
- Trial name
- NCT05408364
- Testing
- probiotic or natural yoghurt, SRP
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Marmara University
Chronic Periodontitis
Grape Seeds Extract Gel as an Adjunct for the Treatment of Chronic Periodontitis
The aim of this study was to formulate a mucoadhesive gel of grapes seed extract (GSE) followed by short-term clinical study for the effectiveness of this gel onto the pocket depth (PD), plaque index (PI), gingival index (GI)…
- Trial name
- NCT02767115
- Testing
- 2% GSE mucoadhesive gel, GSE free mucoadhesive gel
- Where
- Saudi Arabia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Dental Diseases
Amount of Cementum After Scaling, Root Planing and Glycine Air Polishing
The purpose of this study was to evaluate the residual cementum with the histological measurements and root surface topography with SEM evaluation using four periodontal treatment methods.
- Trial name
- NCT02205619
- Testing
- Air Flow Master Piezon®, EMS SA, Nyon, Swiss, Gracey curettes, American Eagle, Missoula, MT, USA, Air-flow® Powder Perio, EMS SA, Nyon, Swiss
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Periodontitis
Impact of Supracrestal Tissue Attachment Dimension on Outcome of Scaling and Root Planing and Open Flap Debridement Procedure in Different Periodontal Phenotypes
The existence of supracrestal tissue attachment (SCTA) is fundamental for adhesion of the junctional epithelium and insertion of the connective fibers to the dental structure, besides functioning as a barrier against microbial…
- Trial name
- NCT05696600
- Testing
- Scaling and root planing and open flap debridement
- Where
- India
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periodontitis
Influence of SRP With MM on the Composition and Functional Characteristics of Subgingival Microbiome Communities
The purpose of this study is to characterize the effect of minocycline microspheres (MM) administered as an adjunct to scaling and rooting planning (SRP) on the subgingival community composition and metatranscriptome functional…
- Trial name
- NCT05422742
- Testing
- SRP + MM, Scaling and Root Planing (SRP)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Periodontitis, Kidney Transplant Recipients
Diode Laser-Assisted Periodontal Therapy in Kidney Transplant Recipients
This randomized controlled trial evaluates the efficacy of diode laser-assisted non-surgical periodontal therapy in kidney transplant recipients with periodontitis.
- Trial name
- KTRs (NCT07532694)
- Testing
- Scaling and Root Planing, Diode Laser
- Where
- 2 sites in Vietnam
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Military Hospital 103
Chronic Periodontitis
Effect of Arthrospira Platensis (Spirulina) as an Adjunct to Scaling and Root Planing on Salivary Antioxidant Levels in Chronic Periodontitis Subjects
Introduction- Oxidative stress plays a causative role in pathogenesis of periodontal disease. It has been reported that Spirulina platensis or its active ingredient C phycocyanin (CPC) exerts anti-inflammatory, anti-oxidative and…
- Trial name
- NCT02886676
- Testing
- Spirulina capsules
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College
Periodontal Diseases
The Effect of an Antioxidant Gel Compared to Chlorhexidine Gel During the Soft Tissue Healing Process: A Randomized Controlled Clinical Trial
This study aims to evaluate the comparative impact of chlorhexidine and antioxidant gel on postoperative biomarkers following SRP.
- Trial name
- Antiox-SRP (NCT06894667)
- Testing
- Antioxidant gel, Antimicrobial gel
- Where
- Kuwait
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kuwait University