Clinical trials: Root Planing
Chronic Periodontitis
Effect of a Locally Delivered Probiotic in Periodontitis
Saccharomyces boulardii is commonly employed as a live non-pathogenic probiotic microbial feed or food supplement. S. boulardii reduces the secretion of key pro inflammatory cytokines and promotes the production of…
- Trial name
- NCT02645669
- Testing
- Study site, Control site
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- SVS Institute of Dental Sciences
Periodontitis
Efficacy of Curcumin Gel Combined With Non-surgical Periodontal Therapy on Salivary Procalcitonin Level in the Treatment of Periodontitis Patients
Objectives: To evaluate the efficacy of curcumin gel as an adjunct to scaling and root planing (SRP) on the salivary procalcitonin level in the treatment of periodontitis.
- Trial name
- NCT05667376
- Testing
- Local drug delivery, curcumin gel
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Reham abdelfatah
Chronic Periodontitis
Effect of Scaling and Root Planing on Serum Renal Function Markers in Chronic Periodontitis Subjects.
ABSTRACT:- Introduction: Chronic periodontitis (CP), the commonest type of periodontal disease, it is an infectious disease resulting in inflammation within of the tissues supporting the teeth, progressive loss of attachment and…
- Trial name
- NCT02636114
- Testing
- scaling and root planing
- Where
- India
- Volunteers
- 51 people
- Sponsor
- Maharashtra University of Health Sciences
Generalized Moderate Chronic Periodontitis, Generalized Severe Chronic Periodontitis
Treatment of Periodontitis With Er:YAG Laser
The purpose of this research project is to gain information on the best and most comfortable way to treat the periodontal disease.
- Conditions
- Generalized Moderate Chronic Periodontitis, Generalized Severe Chronic Periodontitis, Periodontal Diseases
- Trial name
- NCT03628872
- Testing
- Scaling and root planing, Er:YAG Laser, Hand instruments
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Columbia University
Periodontitis
Emblica Officinalis Irrigation in Periodontitis
E. officinalis fruit possesses both the antimicrobial and anti-inflammatory activities that may prove to be useful against several periodontal diseases with the advantage that it is devoid of side effects associated with…
- Trial name
- NCT03295461
- Testing
- SRP+ 10% Emblica officinalis irrigation, SRP + 0.2% Chlorhexidine irrigation), SRP + 0.9% Saline irrigation
- Where
- India
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Periodontitis
Diode Laser and SRP in Chronic Periodontitis
The purpose of this study is to compare the efficacy of photoablative and photodynamic diode laser in adjunct to scaling-root planing (PAPD+SRP) and SRP alone for the treatment of periodontitis.
- Trial name
- PAPD (NCT02407379)
- Testing
- PAPD+SRP
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Odontostomatologic Laser Therapy Center, Florence, Italy
Periodontitis, Cardiovascular Diseases
Periodontal and Cardiovascular Diseases Project
The purpose of this study is to investigate whether basic periodontal therapy aim to reduce subgingival levels of Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans, has an impact on the vascular function of…
- Trial name
- NCT02716259
- Testing
- Scaling and root planing, Supragingival prophylaxis
- Where
- 2 sites in Spain
- Volunteers
- 36 people
- Sponsor
- Universidad Complutense de Madrid
Periodontitis
Local Drug Delivery of Aloe Vera Gel in Chronic Periodontitis
Background: Aloe vera is considered to be the most promising and high-ranking agent as an all-purpose herbal plant amongst herbal agents used in dentistry.
- Trial name
- NCT02462993
- Testing
- Aloe Vera
- Volunteers
- 12 people
- Sponsor
- Dr. D. Y. Patil Dental College & Hospital
Chronic Periodontitis
PDT As An Adjunct To SRP In The Management of Chronic Periodontitis
The present study aims to evaluate photodynamic therapy (PDT) using Zinc oxide as a photosensitizer as an adjunct to scaling and root planing (SRP) in the management of chronic periodontitis.
- Trial name
- NCT03770819
- Testing
- Photodynamic therapy
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- KLE Society's Institute of Dental Sciences
Chronic Periodontitis
Intervention Study of Two Protocols for Non-surgical Treatment of Chronic Periodontitis
Treatment directed towards the control of periodontal infections is to about 90% non-surgical procedures. There is evidence from a large number of randomized controlled studies that the efficacy in terms of clinical outcomes of a…
- Trial name
- NCT02168621
- Testing
- Full-mouth ultrasonic debridement, Section-wise scaling and root planing
- Where
- Sweden
- Volunteers
- 800 people
- Sponsor
- Göteborg University
Periodontitis, Periodontitis (Stage 3)
Evaluation of Albumin Platelet-Rich Fibrin Following SRP in Patients With Periodontitis
The study aims to investigate whether application of albumin platelet-rich fibrin (Alb-PRF) into the gum pockets after scaling and root planing (SRP) can improve healing in patients with Stage III Grade B periodontitis.
- Trial name
- NCT07363135
- Testing
- Albumin platelet-rich fibrin, Sterile saline (0.9%)
- Where
- Turkey (Türkiye)
- Volunteers
- 23 people
- Sponsor
- Saglik Bilimleri Universitesi
Periodontitis, Periodontitis Stage I
Chlorhexidine and Zinc in Non-Surgical Periodontal Therapy
Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth and is associated with both local tissue destruction and systemic inflammatory responses.
- Conditions
- Periodontitis, Periodontitis Stage I, Periodontitis Stage II
- Trial name
- CHX-Zn (NCT07517991)
- Testing
- Chlorhexidine and zinc application, Scaling and root planing with distilled water
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ataturk University
Periodontitis, Diabetes
Full-mouth and Partial-mouth Scaling and Root Planing in Type 2 Diabetic Subjects
The aim of this study will be to evaluate: 1- the effect of full-mouth (FM) scaling and root (SRP) planing in 24 hours associated with or without extensive application of chlorhexidine (CLX) on clinical, microbiological, glycemic…
- Trial name
- NCT02062047
- Testing
- FMSRP, Chlorhexidine, PMSRP
- Volunteers
- 60 people
- Sponsor
- University of Guarulhos
Periodontitis Chronic Generalized Moderate, Periodontitis Chronic Generalized Severe
Clinical Evaluation of Laser Therapy Used as an Adjunct to Non-Surgical Treatment of Gum Disease
The use of lasers to treat various problems in dentistry is growing as it has in medicine. One application is the use of lasers to treat periodontal disease.
- Trial name
- NCT04027686
- Testing
- Laser Therapy, Non-surgical Scaling and Root Planing
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Periodontitis, Periodontal Disease
Photodynamic Therapy as an Adjunct in Periodontal Treatment
This study aims to evaluate the clinical effectiveness of antimicrobial photodynamic therapy (aPDT) as an adjunct to scaling and root planing (SRP) in the treatment of periodontitis.
- Trial name
- PDT-PERIO (NCT07633405)
- Testing
- Scaling and Root Planing, Antimicrobial Photodynamic Therapy
- Where
- Ecuador
- Volunteers
- 30 people
- Sponsor
- Universidad Catolica Santiago de Guayaquil
Uncontrolled Type 2 Diabetes Mellitus, Severe Periodontitis
A Comparison of Single-Stage Full-Mouth Disinfection With Quadrant-Based Scaling and Root Planing in Patients With Uncontrolled Type 2 Diabetes and Severe Periodontitis: An Assessment of Its Impact on Quality of Life
This study evaluated the effects of a single-stage full mouth disinfection (FMD) protocol versus a quadrant-based tooth surface cleaning and root planing (Q-SRP) protocol on changes in clinical periodontal parameters over a…
- Trial name
- NCT07598071
- Testing
- Quadrant based scaling and root planning, full mouth disinfeciton
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Pamukkale University
Periodontal Pocket
Comparative Evaluation of Bromelain-Quercetin Gel With Chlorhexidine Gel as Subgingival Local Drug Delivery Following Scaling and Root Planing In Stage I /II and Grade B Periodontitis - Randomized Control Clinical Trail
Comparative Evaluation of Bromelain-Quercetin Gel With Chlorhexidine Gel as Subgingival Local Drug Delivery Following Scaling and Root Planing In Stage I /II and Grade B Periodontitis - Randomized Control Clinical Trail
- Trial name
- NCT06775392
- Testing
- bromelain-quercetin gel, chlorhexidine gel, SRP
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Periodontitis
L-PRF Plus Non Surgical Periodontal Treatment
Abstract: Background: Leucocyte and Platelet-Rich Fibrin (L-PRF) has shown to promote regenerative processes, even reporting antibacterial effect.
- Trial name
- NCT04520438
- Testing
- Leukocyte and platelet rich fibrin, Non-Surgical Periodontal treatment
- Where
- Chile
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Periodontitis
Amoxicillin and Metronidazole During or After the Periodontal Treatment
This randomized clinical trial aimed to compare the clinical and microbiological effects of different times of administration of metronidazole (MTZ) and amoxicillin (AMX) in the treatment of periodontitis.
- Trial name
- NCT06177119
- Testing
- Scaling and root planing, Metronidazole during SRP, Amoxicillin during SRP
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- Belén Retamal-Valdes
Cyclooxygenase Two Inhibitors, Etoricoxib
EFFECT OF SELECTIVE COX-2 INHIBITOR (ETORICOXIB) ALONG WITH SCALING AND ROOT PLANING (SRP) ON CLINICAL PARAMETERS AND SALIVARY LEVEL OF SUPEROXIDE DISMUTASE IN CHRONIC GENERALIZED PERIODONTITIS A DOUBLE-BLIND, PLACEBO-CONTROLLED, DOUBLE-MASKED RANDOMIZED CONTROLLED TRIAL (RCT).
The hypothesis is that Etoricoxib act as an adjuvant to SRP in alleviating periodontal inflammation by: 1. improving clinical periodontal parameters and, 2. improving the salivary SOD levels.
- Conditions
- Cyclooxygenase Two Inhibitors, Etoricoxib, Periodontitis, Superoxide Dismutase
- Trial name
- NCT02149758
- Testing
- Etoricoxib
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tatyasaheb Kore Dental College