Clinical trials: SBS
Short Bowel Syndrome
Safety and Efficacy Study in Infant With SBS
The objective of this clinical study is to evaluate the efficacy and safety of NTRA-9620 compared with placebo in pediatric subjects (aged 28 weeks postmenstrual age to 52 weeks old) with SBS following surgical resection
- Trial name
- GIFT (NCT02865122)
- Testing
- NTRA-9620
- Where
- 8 sites in United States
- Volunteers
- 2 people
- Sponsor
- Elgan Pharma Ltd.
Short Bowel Syndrome, SBS
A Clinical Study of FT1 in Patients With Short Bowel Syndrome
The goal of this clinical trial is to learn if FT1 is safe and works to treat short bowel syndrome (SBS) in adults. It will also learn about the PK/PD profile of FT1.
- Trial name
- NCT07704047
- Testing
- FT1
- Where
- China
- Volunteers
- 8 people
- Sponsor
- Chongqing Peg-Bio Biopharm Co., Ltd.
Short Bowel Syndrome
Proof of Concept Study in Patients With Short Bowel Syndrome
This is a Phase I/II. proof of concept, open label, two-dose, dose escalation study of NM-002 in adult patients with SBS who previously responded to exenatide.
- Trial name
- NCT04379856
- Testing
- NM-002
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- 9 Meters Biopharma, Inc.
Wound Healing
Rationales for Wound Care Management in Old World Cutaneous Leishmaniasis Patients
The rationales of a clinical trial comparing intralesional antimonial therapy versus wound care management in patients with old world cutaneous leishmaniasis (OWCL) are the following: 1.
- Trial name
- LEICO (NCT00996463)
- Testing
- Electro-thermo-coagulation, Sodium Stibogluconate, DAC N-055
- Where
- Afghanistan
- Volunteers
- 63 people
- Sponsor
- Waisenmedizin e. V. Promoting Access to Essential Medicine
Short Bowel Syndrome
Open-Label Study of Teduglutide for Subjects With PN-Dependent Short Bowel Syndrome (SBS)
This study is a 2-year open label extension study to collect long term efficacy and safety data from patients who have completed the 24-weeks of study drug dosing in CL0600-020.
- Trial name
- NCT00930644
- Testing
- teduglutide
- Where
- 23 sites in United States, Canada and 7 more
- Volunteers
- 88 people
- Sponsor
- Shire
Short Bowel Syndrome (SBS), SBS Associated With Intestinal Failure (SBS-IF)
A Study to Investigate the Efficacy and Safety of Apraglutide Compared With Placebo in Adult Participants With Short Bowel Syndrome Associated With Intestinal Failure (SBS-IF)
This Phase 3 placebo-controlled study is planned to further investigate the efficacy, safety, and tolerability of apraglutide in the overall SBS-IF (short bowel syndrome associated with intestinal failure) population during 24…
- Trial name
- STARS-2 (NCT07742735)
- Testing
- Apraglutide
- Where
- 94 sites in United States, Argentina and 20 more
- Volunteers
- 124 people
- Sponsor
- VectivBio AG
Rotator Cuff Tears
RC Repair Versus Subacromial Balloon Spacer in Older Adults
The purpose of this pilot study is to assess the feasibility of a full randomized trial design.
- Trial name
- NCT05788250
- Testing
- Subacromial spacer implantation, Rotator cuff repair
- Volunteers
- 32 people
- Sponsor
- Panam Clinic
Healthy
The Effect of the SBS Decompression Technique on Gastrointestinal Symptoms During the Menstrual Cycle
Determining the effects of a single application of the sphenobasilar synchondrosis (SBS) decompression technique, on gastrointestinal symptoms during the menstrual cycle is an area that lacks of evidence and proper studies.
- Trial name
- NCT05922189
- Testing
- SBS Decompression Technique
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Tecnologia da Saúde do Porto
Short Bowel Syndrome (SBS)
A Study of Teduglutide in Chinese Children and Teenagers With Short Bowel Syndrome
Short Bowel Syndrome (SBS) is a rare condition that happens when a large part of the bowel (also called intestine) is missing or has been removed because of illness or surgery.
- Trial name
- NCT07319832
- Testing
- No Intervention
- Where
- 4 sites in China
- Volunteers
- 12 people
- Sponsor
- Takeda
Short Bowel Syndrome, Malabsorption
Teen and Young Adult Connections for Support From Multidisciplinary Professionals & Peers
12 month study testing mobile delivery of health information and connections to professionals and peers to improve health of teen/young adult HPN users.
- Conditions
- Short Bowel Syndrome, Malabsorption, Malnutrition
- Trial name
- NCT02987569
- Testing
- mConnect plus mobile connections to multidisciplinary professionals & peers, iPad use plus one mobile connections to multidisciplinary professionals & peers
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- University of Kansas Medical Center
May-Hemalin, Fechtner Syndrome (Disorder)
Phenotypic and Genotypic Identification and Characterization of MYH9-related Constitutional Thrombocytopenia
The research involves the establishment of a cohort including as much as possible cases of macrothrombocytopenia related to a "MYH9 syndrome" and the study of mutations and polymorphisms of MYH9 gene in all these patients.
- Conditions
- May-Hemalin, Fechtner Syndrome (Disorder), Epstein Syndrome (Disorder), MYH9 Related Disorders
- Trial name
- MAGIC-MYH9 (NCT00925236)
- Where
- France
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cutaneous Leishmaniasis
Oral Miltefosine for the Treatment of Pediatric Cutaneous Leishmaniasis in Colombia
The purpose of this randomized, open label clinical trial is to determine if oral miltefosine is a safe and effective alternative, compared with parenteral meglumine antimoniate for the treatment of pediatric Cutaneous caused by…
- Trial name
- NCT00487253
- Testing
- Miltefosine, Meglumine antimoniate
- Volunteers
- 150 people
- Sponsor
- Centro Internacional de Entrenamiento e Investigaciones Médicas
Nonthyroidal Illness Syndrome, Short Bowel Syndrome
Nonthyroidal Illness Syndrome in SBS
Nonthyroidal illness syndrome (NTIS) is prevalent in critical illness; it is associated with poor outcomes. However, few studies have focused on the relationship between NTIS and short bowel syndrome (SBS).
- Trial name
- NCT04450472
- Volunteers
- 51 people
- Sponsor
- Jinling Hospital, China
Cutaneous Leishmaniasis
Treatment of Cutaneous Leishmaniasis With a Combination of Miltefosine and Antimony
Cutaneous leishmaniasis is endemic in the New World and, until recently, the standard treatment was pentavalent antimony. The cure rate for L panamensis in Colombia is 91%-93% and the cure rate in Bolivia is also 90%.
- Trial name
- NCT01380301
- Testing
- Miltefosine and antimony, Miltefosine alone
- Where
- Bolivia
- Volunteers
- 19 people
- Sponsor
- Foundation Fader
SBS - Short Bowel Syndrome
Development and Validation of a Questionnaire to Measure the Impact of SBS and Its Treatments on Patients' Lives
Today, patients express a very strong need to take into account the consequences of their disease and its treatments in their therapeutic follow-up.
- Trial name
- ARTEMIS_GC (NCT04150302)
- Testing
- Exploratory interviews, Semi-directive interviews, Delphi Process
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Central Hospital, Nancy, France
Prematurity, Intestine Perforation
Early Supplementation of Enteral Microlipid With and Without Fish Oil in Premature Infants With Enterostomies
Necrotizing enterocolitis (NEC) and spontaneous intestinal perforation (SIP) are common devastating gastrointestinal diseases in premature infants.
- Conditions
- Prematurity, Intestine Perforation, Necrotizing Enterocolitis (NEC), Short Bowel Syndrome (SBS)
- Trial name
- EMLFO-2 (NCT01674478)
- Testing
- Microlipid with fish oil, Microlipid
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Wake Forest University
Coronary Disease, Heart Diseases
Clinical Efficacy of Stent-balloon-stent (SBS) Technique in the Treatment of Coronary Bifurcation Lesions
The treatment of coronary bifurcation lesions continue to remain challenges. Due to the special hemodynamics caused by the special anatomical structure of the coronary bifurcation, it is easy to cause vascular crest displacement…
- Conditions
- Coronary Disease, Heart Diseases, Cardiovascular Diseases, Vascular Diseases
- Trial name
- NCT06045039
- Testing
- Stent-balloon-stent (SBS) technique
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
Cutaneous Leishmaniasis
Reduced Doses of Antimony Plus Ranulocyte Monocyte Colony Stimulating Factor (GM-CSF) for Cutaneous Leishmaniasis
The present study was designed as a randomized, single blind, placebo-controlled, study to evaluate the effect of 400 µg of recombinant human GM-CSF applied intralesionally and associated with half of the total dose of antimony…
- Trial name
- GMCSFSbv (NCT00973128)
- Testing
- GMCSF plus Antimony reduced dose, Meglumine antimoniate
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Hospital Universitário Professor Edgard Santos
Short Bowel Syndrome
Registry for Participants With Short Bowel Syndrome
This is a global prospective, observational, multi-center registry to evaluate the long-term safety profile for participants with short bowel syndrome (SBS) who are treated with teduglutide in a routine clinical setting.
- Trial name
- NCT01990040
- Where
- United States
- Volunteers
- 1,806 people
- Sponsor
- Shire
Short Bowel Syndrome, Intestinal Resection
Gastrointestinal Hormone Secretion, Intestinal Permeability and Short Bowel Syndrome
The gastrointestinal tract is a complex endocrine organ that regulates a wide range of physiological processes, including those involved in the digestion of nutrients.
- Trial name
- NCT07235670
- Testing
- Standardized meal
- Where
- Denmark
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet