Clinical trials: ST-elevation Myocardial Infarction (STEMI)
Left Ventricular Function Systolic Dysfunction, Left Ventricular Function Diastolic Dysfunction
Cell Therapy in Diabetic Patients With ST-Segment Elevation Myocardial Infarction(STEMI)
The purpose of this study is to investigate the efficacy and mechanism of bone marrow mononuclear cells (BMMNC) transplantation for diabetic and non-diabetic patients with ST-segment elevation myocardial infarction (STEMI)who…
- Conditions
- Left Ventricular Function Systolic Dysfunction, Left Ventricular Function Diastolic Dysfunction, Death, Myocardial Reperfusion Injury
- Trial name
- NCT01307371
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Xijing Hospital
STEMI
OCT Guided Magmaris RMS in STEMI
Percutaneous treatment of coronary artery disease depends on the implantation of stents within diseased coronary segments. Compared with conventional bare-metal and drug- eluting stents, which remain permanently within the…
- Trial name
- BESTMAG (NCT03955731)
- Testing
- Magmaris resorbable magnesium scaffold
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Myocardial Infarction
Functional Coronary Angiography Guided Revascularization in STEMI
The goal of this multicenter randomized clinical trial is to test the superiority in terms of efficacy of the Angiography-derived fractional flow reserve (AIR) over that based on conventional angiography (ANGIO) strategy in the…
- Trial name
- AIR-STEMI (NCT05818475)
- Testing
- Angiography-guided PCI, Angiography-derived FFR PCI indication and planning
- Where
- 22 sites in Italy, Pakistan
- Volunteers
- 1,823 people
- Sponsor
- University Hospital of Ferrara
Cardiovascular Diseases, STEMI
Exercise Echocardiography on LV Mechanics in Patients With CAD: a Speckle-tracking Echocardiography
Recovering blood flow to a coronary stenosis may improve left ventricular (LV) function in patients with coronary artery disease (CAD).
- Conditions
- Cardiovascular Diseases, STEMI, NSTEMI
- Trial name
- NCT04824001
- Testing
- exercise stress echocardiography
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- China Medical University Hospital
Non ST Elevation Myocardial Infarction
Clinical Effects of Eptifibatide Administration in High Risk Patients Presenting With Non-ST Segment Elevation Acute Coronary Syndrome (NSTE-ACS) Requiring Urgent Coronary Artery Bypass Graft Surgery in Short- and Long-Term Follow-up
1. INTRODUCTION Through last couple of years the number of patients treated for acute coronary event without persistent ST segment elevation in ECG has been growing.
- Trial name
- NCT01863134
- Testing
- Eptifibatide
- Where
- 6 sites in United States, Poland
- Volunteers
- 140 people
- Sponsor
- Medical University of Silesia
STEMI - ST Elevation Myocardial Infarction, Inflammation
Low-Level Transcutaneous Vagus Stimulation in ST Segment Elevation Myocardial Infarction: TREAT MI Study
This study will determine the impact of Transcutaneous Vagus Stimulation(TVNS) and autonomic modulation of inflammation in patients admitted with " acute heart attack." After admission for "acute heart attack" or "myocardial…
- Trial name
- TREATMI (NCT03284281)
- Testing
- Tragus stimulator
- Where
- United States
- Sponsor
- University of Oklahoma
Chest Pain, Acute Coronary Syndromes (ACS)
ECG-less Coronary Computed Tomography Angiography in the Management of Patients Presenting With High-troponin Chest Pain
Chest pain represents a common reason for consultation to emergency room. This symptom can be explained by a broad spectrum of conditions, from benign musculoskeletal or esophageal pain to life-threatening disease such as aortic…
- Trial name
- ECLECTIC (NCT07192965)
- Testing
- Non-ECG-gated computed tomography
- Where
- Belgium
- Volunteers
- 230 people
- Sponsor
- Universitair Ziekenhuis Brussel
Acute Myocardial Infarction (AMI)
Fast Discharge After Acute Myocardial Infarction Discharge MI
To evaluate the hypothesis that a fast discharge strategy (discharge at 24 [± 12] hours) following invasive management for acute myocardial infarction is non-inferior to standard of care (>36 hours) with respect to the risk of…
- Trial name
- DISCHARGE-MI (NCT06744322)
- Testing
- Fast discharge strategy
- Where
- 8 sites in Austria, Germany
- Volunteers
- 2,070 people
- Sponsor
- Medical University Innsbruck
ST-Segment Elevation Myocardial Infarction, Multivessel Coronary Artery Disease
The FAVOR V AMI Trial
The FAVOR V AMI study is a prospective, multicenter, blinded, randomized, sham-controlled trial comparing the long-term clinical outcomes of the "Functional and Angiography-derived Strain inTegration (FAST)" technique…
- Conditions
- ST-Segment Elevation Myocardial Infarction, Multivessel Coronary Artery Disease, Percutaneous Coronary Intervention
- Trial name
- NCT05669222
- Testing
- FAST Technique, Angiography
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- China National Center for Cardiovascular Diseases
Myocardial Infarction, Coronary Disease
Randomized Comparison of Abciximab Plus Heparin With Bivalirudin in Acute Coronary Syndrome
The purpose of this study is to determine which of these anti-clotting medications, abciximab plus unfractionated heparin or bivalirudin, is more effective to prevent thrombotic and bleeding complications in patients suffering…
- Trial name
- ISAR-REACT-4 (NCT00373451)
- Testing
- Abciximab + UFH, Bivalirudin, Heparin
- Where
- 9 sites in Germany, Italy
- Volunteers
- 1,721 people
- Sponsor
- Deutsches Herzzentrum Muenchen
ST Elevation Myocardial Infarction
Selective Aspiration Thrombectomy in STEMI
Patients who were diagnosed with ST-elevation myocardial infarction (STEMI) and received primary percutaneous coronary intervention (PPCI) from July 2009 to December 2011 were identified from the National Health Insurance…
- Trial name
- NCT03841487
- Testing
- Aspiration thrombectomy
- Where
- Taiwan
- Volunteers
- 9,100 people
- Sponsor
- Chang Gung Memorial Hospital
Chest Pain, ST Elevation Myocardial Infarction
The Accuracy of the Mini RELF Device for the Diagnosis of an Acute Coronary Artery Occlusion.
Patient delay in seeking medical attendance for symptoms of acute ST elevation myocardial infarction (STEMI) is the major obstacle to reduce the current mortality from acute coronary syndromes.
- Trial name
- RELF IIa (NCT02983396)
- Testing
- Diagnostic accuracy of Mini Relf Device
- Where
- 3 sites in Belgium
- Volunteers
- 64 people
- Sponsor
- University Ghent
Myocardial Infarction, Cardiovascular Disease
Thromboelastography As A Tool for Possible Clopidogrel Resistance in The Patients Treated With Primary PCI for STEMI
Determine usefulness of thromboelastography (TEG) as a valuable tool in ex-vivo assessing platelet response to aspirin and clopidogrel (dual) treatment and on-treatment platelet reactivity during acute ST segment elevation…
- Trial name
- NCT00517478
- Testing
- Blood Sample
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Assaf-Harofeh Medical Center
ST Segment Elevation Myocardial Infarction, Myocardial Oedema
Myocardial Oedema in ST Segment Elevation Myocardial Infarction Myocardial
Cardiac magnetic resonance imaging (CMR) is a non invasive technique used to obtain functional and anatomical information on the heart.
- Trial name
- NCT01897350
- Testing
- Cardiac magnetic resonance imaging
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Elisa McAlindon
Acute ST Segment Elevation Myocardial Infarction
Performance of Bioresorbable Scaffold in Primary Percutaneous Intervention of ST Elevation Myocardial Infarct
Patients presenting with acute ST elevation myocardial infarct urgently need revascularization. Standard of care is establishing bloodflow through the coronary vessels using thrombus aspiration catheter, and securing the result…
- Trial name
- BVS in STEMI (NCT02067091)
- Testing
- stent implant in a coronary artery
- Where
- 2 sites in Denmark, Norway
- Volunteers
- 120 people
- Sponsor
- Haukeland University Hospital
Acute Coronary Syndrome
A Study to Evaluate the Safety of 12 Weeks of Dosing With GW856553 and Its Effects on Inflammatory Markers, Infarct Size, and Cardiac Function in Subjects With Myocardial Infarction Without ST-segment Elevation
This is a randomized, double-blind, placebo-controlled, parallel group, multi-center study to evaluate initial safety and efficacy of GW856553 in subjects with NSTEMI.
- Trial name
- Solstice (NCT00910962)
- Testing
- GW856553
- Where
- 108 sites in United States, Australia and 7 more
- Volunteers
- 526 people
- Sponsor
- GlaxoSmithKline
Stable Angina, Unstable Angina
Optical Coherence Tomography Comparison of Neointimal Coverage Between CRE8 DES and BMS
The purpose of the study is to demonstrate the non-inferiority of Cre8 (CID) Drug Eluting Stent, studied 3 months after implant, compared to Vision/Multilink8 Bare Metal Stent (Abbott) studied at 1 month, in terms of neointimal…
- Conditions
- Stable Angina, Unstable Angina, NSTEMI
- Trial name
- DEMONSTRATE (NCT01543373)
- Testing
- Amphilimus Eluting Stent, Bare Metal Stent
- Where
- 6 sites in Italy, Netherlands
- Volunteers
- 38 people
- Sponsor
- CID - Carbostent & Implantable Devices
Effect of Diabetes on Long Term Excess Mortality Following Acute Myocardial Infarction
Long Term Excess Mortality of Acute Myocardial Infarction in Patients With and Without Diabetes: A Population-based Cohort Study
Diabetes is key risk factor for death following acute myocardial infarction. However, the long-term excess risk of death associated with diabetes following acute myocardial infarction not known.
- Trial name
- NCT02591576
- Volunteers
- 700,000 people
- Sponsor
- University of Leeds
Microvascular Obstruction (MVO), STEMI - ST Elevation Myocardial Infarction
Microvascular Obstruction Diagnosis Using the CoFI™ System Assessment - II
A prospective, multicenter, international single-arm, pivotal clinical study designed to validate the performance of the CoFI system in detecting MVO in STEMI subjects, as confirmed by CMRI.
- Trial name
- MOCA II (NCT06909578)
- Testing
- CorFlow Controlled Flow Infusion System - CoFI™
- Volunteers
- 200 people
- Sponsor
- CorFlow Therapeutics AG
STEMI - ST Elevation Myocardial Infarction
Clinical Characteristics and Prognosis of STEMI Patients Undergoing Primary Percutaneous Coronary Angioplasty and Angiographic Data
Gensini score (GS) provides valuable information on severity and prognosis of coronary artery disease (CAD). We aim to evaluate the relationship between the severity of CAD determined by the GS and short and long term of…
- Trial name
- NCT05679843
- Volunteers
- 3,000 people
- Sponsor
- Central Hospital, Nancy, France
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