Clinical trials: STI Prevention
Suicidal Ideation and Behavior, HIV
HIV Suicide Prevention With AI-DBT
One in four older persons living with HIV/AIDS (PLWHA) report at least one suicide attempt in their lifetime, and the risk for death by suicide is 100 times higher in PLWHA than in the general population.
- Conditions
- Suicidal Ideation and Behavior, HIV, AIDS (Acquired Immune Deficiency Syndrome)
- Trial name
- NCT07339189
- Testing
- AI-DBT
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Rutgers, The State University of New Jersey
HIV Infections
Effectiveness of a Cell Phone-Based Program for Abstinence and HIV Risk Prevention
This study will develop and test the effectiveness of a cell phone-based text messaging program to encourage abstinence, monogamy, or condom use among black urban males in Philadelphia, Pennsylvania.
- Trial name
- NCT00601237
- Testing
- HIV-related text messaging, Nutrition-related text messaging
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Sexually Transmitted Diseases, Pregnancy
Internet-Based Sexual Health Education for Middle School Native American Youth
This study will evaluate the effect of an American Indian/Alaska Native (AI/AN) adaptation of the It's Your Game…Keep It Real (IYG) intervention, relative to a comparison condition on sexual behavior outcomes and psychosocial…
- Conditions
- Sexually Transmitted Diseases, Pregnancy, HIV Infections
- Trial name
- IYG-AI/AN (NCT01303575)
- Testing
- HIV, STI and Pregnancy Prevention Curriculum, Control Curricula
- Where
- 4 sites in United States
- Volunteers
- 574 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
HIV Infections
Study of Cell Phone SMS Messages for Prevention of Maternal to Child Transmission of HIV
Optimal development of sustainable health systems must use locally relevant infrastructure. Mobile phone technology, driven primarily by local market forces rather than foreign assistance, is spreading rapidly through African…
- Trial name
- NCT01157442
- Testing
- cell phone sms text messaging
- Where
- Kenya
- Volunteers
- 856 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Cervical Cancer, Breast Cancer
Sexual Health Empowerment for Women's Health
The purpose of this study is to expand the reach of an existing cervical cancer literacy and prevention intervention- the Sexual Health Empowerment (SHE) Project .
- Conditions
- Cervical Cancer, Breast Cancer, Contraceptive Usage, Sexually Transmitted Diseases
- Trial name
- SHE-WOMEN (NCT03984695)
- Testing
- SHE-WOMEN
- Where
- United States
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
HIV Infection
Factors Affecting PrEP Adherence
The purpose of this study is to test a new way to take a questionnaire that asks about adherence (whether the person is taking the medicine correctly). This new questionnaire is called Interactive Questionnaire System (iQS).
- Trial name
- NCT02411630
- Testing
- Emtricitabine/tenofovir disoproxil
- Where
- 12 sites in United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
HIV/AIDS
Motivation Matters Study
The study aims to develop and evaluate the efficacy and causal mechanisms of an interactive SMS intervention to optimize individual health and secondary HIV prevention benefits of ART in HIV-positive FSWs.
- Trial name
- MM (NCT02627365)
- Testing
- Individualized, interactive short messaging intervention
- Where
- Kenya
- Volunteers
- 119 people
- Sponsor
- University of Washington
Pregnancy, Malaria
Evaluation of Alternative Antimalarial Drugs for Malaria in Pregnancy
The study aims at comparing the safety, tolerability and efficacy of Mefloquine (MQ) to Sulfadoxine-Pyrimethamine (SP) as Interment Preventive Treatment in pregnancy (IPTp) for the prevention of malaria effects on the mother and…
- Conditions
- Pregnancy, Malaria, HIV Infections
- Trial name
- MiPPAD (NCT00811421)
- Testing
- Sulphadoxine-pyrimethamine, Mefloquine (full dose), Mefloquine (split dose)
- Where
- 5 sites in Benin, Gabon and 3 more
- Volunteers
- 5,820 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
HIV Infections, Substance Use
SmartSteps: A Context-Aware, PrEP Adherence Intervention for Individuals With Substance Use Disorder
This is a single-arm, observational study of HIV-negative MSM with substance use disorder. Those who meet pre-screening criteria will attend a Screening Visit (Visit 1), where the informed consent process will be conducted and…
- Conditions
- HIV Infections, Substance Use, Adherence, Medication, Adherence, Treatment
- Trial name
- SmartSteps (NCT05378399)
- Testing
- Descovy or Truvada, ID-Cap System, Beiwe
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Brigham and Women's Hospital
HIV, STI
Parrying the Pitfalls of PrEP: Project PEACH
The study is a prospective cohort of young MSM who are followed for 2 years either in-person at the PRISM Health Research Clinic and/or virtually with telehealth study visits.
- Trial name
- NCT05072093
- Testing
- PrEP discontinuation intervention, Offering of on-demand oral PrEP, Offering of STI PEP
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Emory University
HIV Infection, Human Immunodeficiency Virus
Evaluation of the Safety of a Polyvalent Virus in Healthy Adults
This is a research study to evaluate the safety of a vaccine to protect people from HIV infection. Human Immunodeficiency Virus (HIV) is the cause of AIDS (Acquired Immune Deficiency Syndrome).
- Trial name
- NCT00187044
- Testing
- PolyEnv1 vaccine
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Chlamydia
Multi-level Interventions for STD Prevention Among Adolescents
Sexually active adolescents between the ages of 10 and 19 are at extremely high risk for sexually transmitted diseases (STD), including HIV, and teen pregnancy.The overall goal of this research program is to develop, implement…
- Trial name
- NCT00146406
- Testing
- Project Connect
- Where
- United States
- Volunteers
- 36,502 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
HIV Infections
PrEP Among MSM and TG in Myanmar
HIV is concentrated among key populations in Myanmar. Globally, HIV-prevalence among transgender (TG) women is one of the highest; laboratory-confirmed prevalence is reported up to 40%.
- Trial name
- PrEP (NCT04781426)
- Testing
- Tenofovir Disoproxil Fumarate (TDF) 300 mg
- Where
- Burma
- Volunteers
- 200 people
- Sponsor
- Myanmar Oxford Clinical Research Unit
Human Immunodeficiency Virus
Efficacy Study of Different Laboratory Management Strategies and Drug Regimens in HIV-infected Children in Africa
The two original objectives were to determine in HIV-infected children initiating antiretroviral therapy (ART): 1. Whether clinically driven monitoring (CDM) will have a similar outcome in terms of disease progression or death as…
- Trial name
- ARROW (NCT02028676)
- Testing
- Clinically Driven Monitoring (CDM), Laboratory plus Clinical Monitoring (LCM), Arm A: ABC+3TC+NNRTI
- Where
- 4 sites in Uganda, Zimbabwe
- Volunteers
- 1,206 people
- Sponsor
- Medical Research Council
HIV
Pre-Exposure Prophylaxis (PrEP) Provision for Ugandan Fisherfolk
This study is a pilot test of enhancements to the standard of care for providing PrEP in Ugandan fishing communities. The specific aims are to conduct a mixed-methods study assessing enhancements to the standard of care for…
- Trial name
- NCT05084716
- Testing
- Enhanced PrEP provision
- Where
- 2 sites in Uganda
- Volunteers
- 885 people, healthy volunteers welcome
- Sponsor
- RAND
Male Circumcision, HIV Prevention
Cohort Field Study to Assess the Safety and Efficacy of the PrePex Device for Non-Surgical Circumcision When Performed by Nurses
A range of observational and epidemiological studies have shown that the lifetime risk of HIV infection can be reduced by 70% through male circumcision.
- Trial name
- NCT01434628
- Testing
- PrePex™ device
- Where
- Rwanda
- Volunteers
- 590 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Rwanda
Virus-HIV
Missed Opportunities to Pre-exposure Prophylaxis for HIV Infection on Person Newly Diagnosed With HIV
Missed opportunity to pre-exposure prophylaxis is a survey study that will be addressed to newly infected with human immunodeficiency virus (HIV) persons.
- Trial name
- NCT03671291
- Testing
- self-administrated questionnaire
- Where
- France
- Volunteers
- 596 people
- Sponsor
- French National Agency for Research on AIDS and Viral Hepatitis
Pre-Exposure Prophylaxis, STI
Community-based Venues for Delivery of Healthcare Services: Proof of Concept Pilot
The investigators propose to offer a package of evidence-based health services to women in two hair salons in the Umlazi township of Durban.
- Conditions
- Pre-Exposure Prophylaxis, STI, Contraceptive Usage
- Trial name
- NCT04222504
- Testing
- Provision of sexual health preventative services in the salon setting
- Where
- South Africa
- Volunteers
- 436 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Capacity Building, Drug Use
Methadone Maintenance and HIV Prevention: A Window of Opportunity in China
This study is an intervention pilot that integrates the current methadone maintenance treatment (MMT) program in China with psychosocial and behavioral components in order to address the critical link between drug use and…
- Conditions
- Capacity Building, Drug Use, HIV/AIDS
- Trial name
- MMT1 (NCT01532609)
- Testing
- MMT CARE
- Where
- China
- Volunteers
- 220 people
- Sponsor
- University of California, Los Angeles
Human Immunodeficiency Virus
Use of the Shang Ring Circumcision Device in Boys Below 18 Years Old in Kenya
A proof of concept study to evaluate the feasibility of using the Shang Ring, a novel male circumcision device across all childhood age groups namely infants (under 1), 1-5 age group, 6-12 age group and the 13-17 age group.
- Trial name
- NCT01891409
- Testing
- Male circumcision using the Shang Ring device
- Where
- Kenya
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- EngenderHealth