Clinical trials: Saccadic Eye Movements
Concussion Post Syndrome
The Effect of Binasal Occlusion on Balance Following a Concussion
This study evaluates the effect of binasal occlusion (BNO) glasses on balance and eye movement in adults with dizziness after a concussion.
- Trial name
- NCT03355339
- Testing
- Binasal occlusion, No binasal occlusion
- Volunteers
- 40 people
- Sponsor
- University of Ottawa
Saccadic Eye Movements
The Effect of Sedation on Eye Movements
The purpose of this study is to determine whether sedation affects saccadic eye movements.
- Trial name
- Eye Movement (NCT00646646)
- Testing
- propofol, dexmedetomidine, Midazolam
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Reflex, Abnormal, Bilateral Vestibulopathy
Covert Saccade Triggers in Bilateral Vestibular Hypofunction
Patients with chronic bilateral vestibular hypofunction may suffer from a visual instability during head movement called oscillopsia.
- Conditions
- Reflex, Abnormal, Bilateral Vestibulopathy, Healthy Volunteers
- Trial name
- CS-TRIGGER (NCT04268615)
- Testing
- Covert Saccades and Virtual Reality, Actives versus passives Head Impulses, Visually guided saccades
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Glaucoma, Open-Angle
Saccadic Eye Movements Are Impaired In Glaucoma
The purpose of this study is to determine whether rapid eye movements called saccades are impaired in glaucoma, a neurodegenerative disease of visual pathways.
- Trial name
- NCT01254058
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Unity Health Toronto
Saccadic Eye Movement Deficiency, Oculomotor Deficiency
Study of Eye Movement Testing and Therapy
The purpose of this study is to determine the ability of several eye movement monitors, used in clinical practice, to identify children with poor reading eye movements.
- Conditions
- Saccadic Eye Movement Deficiency, Oculomotor Deficiency, Oculomotor Dysfunction
- Trial name
- NCT00472485
- Testing
- eye movement therapy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Niemann Pick Diseases
Saccadic Eye Movements in Patients With Niemann-Pick Type C Disease
This study is done in conjunction with a trial, conducted at Columbia University College of Physicians and Surgeons in New York and the Royal Manchester Children's Hospital in England, to examine the effectiveness of a new drug…
- Trial name
- NCT00316498
- Testing
- OGT918
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 30 people
- Sponsor
- National Eye Institute (NEI)
Coronary Artery Disease, Acute Cerebrovascular Accident
Incidence of Acute Cerebrovascular Events Using Either Minimized or Standard Cardiopulmonary Bypass Circuit
The prospective, randomized, two centre study investigates acute cerebrovascular events during extracorporal circulation and the early post operative outcome when using either the minimized cardiopulmonary bypass circuit…
- Conditions
- Coronary Artery Disease, Acute Cerebrovascular Accident, Intracranial Embolism, Embolism, Air
- Trial name
- ROCsafeTM (NCT00862160)
- Testing
- ROCsafeTM
- Where
- 2 sites in Germany
- Volunteers
- 64 people
- Sponsor
- Hannover Medical School
Central Vision Loss From Macular Diseases
Training to Modify Fixational Eye Movements for Optimizing Visual Performance in People With Central Vision Loss
People with central vision loss almost all have exaggerated fixational eye movements when compared with people with normal vision (e.g. larger amplitudes of microsaccades and ocular drifts).
- Trial name
- NCT06670989
- Testing
- Fixation training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Stammering
Modifying Unconscious Tongue Movements in Adults With Developmental Stammer.
This is a pilot randomised controlled trial investigating whether using modification of saccadic eye movements can control lateral unconscious tongue positioning and enhance fluency in adults with a confirmed developmental…
- Trial name
- NCT04310436
- Testing
- Modifying saccades by looking down to naval., Modifying saccades by looking in air.
- Where
- Ireland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Institute of Technology, Sligo
Hemianopia, Homonymous
Comparative Efficacy of Saccadic and Biofeedback Training in Homonymous Hemianopia
This pilot study aims to understand how eye movements change in people with vision loss from stroke after completing one of two types of training.
- Trial name
- NCT06638619
- Testing
- Biofeedback Fixation Training, Saccadic Reading Training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Alabama at Birmingham
Healthy Volunteer, Neurodegenerative Diseases
Visual Motor Coordination
Background: The relation between eye movement and brain function is a subject of interest to the National Eye Institute. By comparing eye movement in healthy volunteers to research conducted on patients who have difficulty moving…
- Trial name
- NCT00568243
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Ataxia Telangiectasia, Dysmetria
Videoocular Assessment of Eye Movement Activity in an Ataxia Telangiectasia
Ataxia-telangiectasia (A-T) is a multisystem auto-somal recessive disorder linked to the A-T mutated gene (ATM) on chromosome 11q22-23, and characterized by progressive neural degeneration, immunodeficiency, and progressive…
- Trial name
- NCT05471310
- Where
- Russia
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Major Depressive Disorder, Bipolar Disorder
An Eye Tracking Study of Affective Disorder Patients With Suicide Risk
This research tries to investigate the validity and reliability of eye-tracking technologies by using different paradigms (eg. free-view, pro-saccade and anti-saccade) which served as a novel way of evaluating suicide risk among…
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Suicide
- Trial name
- NCT03711045
- Testing
- eye-tracking
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Central South University
Physical Function, Executive Function (Cognition)
Effects of Resistance and Dual-Task Training on Physical, Oculomotor, and Executive Functions in Older Adults With MCI
The goal of this clinical trial is to determine the effect of a combined therapeutic intervention program with anaerobic exercises (resistance exercises) and dual tasks on the physical, oculomotor, and executive functions of…
- Conditions
- Physical Function, Executive Function (Cognition), Saccadic Eye Movements
- Trial name
- NCT07278141
- Testing
- Anaerobic therapeutic exercises (resistance exercise), Anaerobic therapeutic exercises (resistance exercise) plus Dual Task
- Where
- 2 sites in Chile, Spain
- Volunteers
- 66 people
- Sponsor
- Universidad Santo Tomas, Chile
Childhood Cancer, Cognitive Impairment
Cognitive and Motor Training in Pediatric Posterior Fossa Tumor Survivors
The purpose of this study is to create a rehabilitation program for children who survived posterior fossa tumors using the latest technology.
- Conditions
- Childhood Cancer, Cognitive Impairment, Motor Skills Disorders, Posterior Fossa Tumor
- Trial name
- NCT03951246
- Testing
- Cognitive and Motor Training
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Federal Research Institute of Pediatric Hematology, Oncology and Immunology
Myasthenia Gravis
Pilot Study: Use of the Saccadometer to Detect Characteristic Saccadic Peak Velocity in Myasthenia Gravis Patients
Fast eye movements have been shown to demonstrate characteristics that are specific to myasthenia gravis that are not present in other eye movement disorders.
- Trial name
- NCT06501794
- Testing
- Quantitative measurement of eye movements
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Gaucher Disease
OGT 918-006: A Phase I/II Randomized, Controlled Study of OGT 918 in Patients With Neuronopathic Gaucher Disease
Gaucher disease is an inherited functional deficiency of glucocerebrosidase. This enzyme breaks down a fatty substance (lipid) called glucocerebroside, which is present in all cells of the body.
- Trial name
- NCT00041535
- Testing
- OGT 918
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 30 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Eye Movements, Attention
An Investigation of Attentional and Inhibitory Processes During Active Visual Search in Humans
The goal of this study is to investigate the finding that there are large individual differences in how participants move their eyes during active visual search.
- Conditions
- Eye Movements, Attention, Executive Function
- Trial name
- NCT06587113
- Testing
- Contour Search Task, Stop signal Task, Useful field of View
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Vestibular Diseases
Covert-saccades, Dynamic Visual Acuity and Quality of Life
Patients with chronic bilateral vestibular hypofunction may suffer from a visual instability during head movement called oscillopsia.
- Trial name
- COSQOL (NCT02753179)
- Testing
- Head Impulse Tests, Dynamic visual acuity Test (DVAT), VEMPs & VEMPo
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon