Clinical trials: Sacrocolpopexy
Pelvic Organ Prolapse, Urinary Incontinence
Prospective Cohort Study of Robotic Assisted Laparoscopic Sacrocolpopexy Using MPATHY Restorelle Mesh
Robotic approach to sacral colpopexy is a relatively new procedure. The literature is scarce in regard to long term outcome. This advanced procedure is offered at Morristown Memorial.
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence, Mesh Erosion
- Trial name
- MPATHY (NCT01320618)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
Genital Prolapse
Real-Life Use of Transabdominal Restorelle® Meshes in Apical Prolapse Repair
The purpose of this study is to prospectively follow patients after a sacrocolpopexy with Restorelle® mesh for apical prolapse repair as part of routine care.
- Trial name
- REPAIR (NCT06296316)
- Testing
- Restorelle Polypropylene Mesh
- Where
- 6 sites in France
- Volunteers
- 39 people
- Sponsor
- Coloplast A/S
Pelvic Organ Prolapse
Abdominal Colpopexy: Comparison of Endoscopic Surgical Strategies
The purpose of this research is to determine if there is a difference in total costs of care and return to health in women who undergo a laparoscopic abdominal sacrocolpopexy (ASC) compared to those undergoing the same procedure…
- Trial name
- ACCESS (NCT01124916)
- Testing
- Robotic assisted laparoscopic abdominal sacrocolpopexy, Standard laparoscopic abdominal sacrocolpopexy
- Where
- 2 sites in United States
- Volunteers
- 84 people
- Sponsor
- Loyola University
Vaginal Vault Prolapse
Restorelle® Y Mesh vs. Vertessa® Lite Y Mesh for Laparoscopic and Robotic-assisted Laparoscopic Sacrocolpopexy
This is a randomized clinical trial to compare outcomes between the Restorelle® Y mesh and Vertessa® lite Y mesh for the treatment of vaginal vault prolapse.
- Trial name
- Lite-Y (NCT03681223)
- Testing
- Vertessa® Lite Y mesh, Restorelle® Y mesh, Laparoscopic sacrocolpopexy
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- The Cleveland Clinic
Pelvic Organ Prolapse
Composite Graft Use in Abdominal Sacrocolpopexy Reduces Erosion Rates
This study is to determine whether the use of a composite biologic/synthetic graft during abdominal sacrocolpopexy leads to a lower rate of erosion while maintaining durability.
- Trial name
- NCT00581412
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, Irvine
Vaginal Hysterectomy, Laparoscopic Supracervical Hysterectomy
Vaginal Hysterectomy vs Supracervical Hysterectomy at the Time of Sacrocolpopexy
The primary objective of the proposed study is to determine the difference in surgical time between minimally invasive (laparoscopic) sacrocolpopexy performed with concurrent vaginal hysterectomy versus laparoscopic supracervical…
- Trial name
- ColoplastLSC (NCT04797585)
- Testing
- Laparoscopic supracervical hysterectomy, Vaginal hysterectomy
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- The Cleveland Clinic
Vaginal Vault Prolapse
Laparoscopic Sacropexy With Robot-Assisted Surgical System
The aim of the study is to evaluate safety and outcome of robot-assisted laparoscopic sacropexy regarding perioperative data, objective anatomical results and postoperative quality of life.
- Trial name
- RobPex (NCT00886223)
- Testing
- laparoscopic robot-assisted sacropexy
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kantonsspital Aarau
Prolapse
Affixing Polypropylene Mesh Using Barbed Suture (Quill™ SRS) During Robotic Assisted Laparoscopic Sacrocolpopexy
1.0 STUDY OBJECTIVE 1.1 PRIMARY OBJECTIVE - To compare two methods of polypropylene mesh attachment during robotic assisted laparoscopic sacrocolpopexy (RALSC): running technique using self-anchoring 1 barbed delayed absorbable…
- Trial name
- Quill RALSC (NCT01608568)
- Testing
- Device is the type of suture used: Quill suture vs. Interrupted suture
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Pelvic Organ Prolapse
Anchor for Robotic Sacrocolpopexy
1. PRIMARY OBJECTIVE: To assess the effect of absorbable anchor compared to suturing for mesh attachment to vagina in robotic assisted sacrocolpopexy on the length of surgery for this portion of the procedure. 2.
- Trial name
- ARiSe (NCT03378622)
- Testing
- Anchor, Suture
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Apical Prolapse, Sacrocolpopexy
Evaluation of the Use of Synthetic Glue for Mesh Fixation in Laparoscopic Sacrocolpopexy
The aim of the study is to evaluate the effect of cyanoacrylate adhesive in laparoscopic sacrocolpopexy, which is the gold standard treatment for apical prolapse.
- Conditions
- Apical Prolapse, Sacrocolpopexy, Glue Fixation
- Trial name
- LSCGlue (NCT06872983)
- Testing
- cyanoacrylate tissue adhesive beside sutures, Suture
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- Brno University Hospital
Pelvic Organ Prolapse
VNOTES Approach in Mesh Free Sacrocolpopexy: A Functional and Anatomic Evaluation
This study aims to evaluate the effectiveness of mesh-free sacrocolpopexy performed using the VNOTES (Vaginal Natural Orifice Transluminal Endoscopic Surgery) technique in the surgical treatment of pelvic organ prolapse.
- Trial name
- vnotes (NCT07114029)
- Testing
- Mesh-free Sacrocolpopexy via VNOTES
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Prolapse
Randomized Trial of Y Mesh vs Dual Mesh
The primary objective of the proposed study is to determine the difference in suturing time when using the restorelle Y mesh versus the restorelle dual flat mesh at the time of laparoscopic and robotic-assisted laparoscopic…
- Trial name
- NCT02156687
- Testing
- Y mesh, Dual flat mesh
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- The Cleveland Clinic
Pelvic Organ Prolapse
Comparison of Vaginal Axis on MRI in Alternative Apical Prolapse Surgeries to Sacrocolpopexy
Sacrocolpopexy remains the preeminent modality in addressing apical prolapse surgically. Nevertheless, amplified morbidity rates within cohorts characterized by obesity and advanced age constrain the advantages conferred by the…
- Trial name
- NCT06072456
- Testing
- laparoscopic lateral suspension, laparoscopic pectopexy, Sacrospinous ligament fixation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Vaginal Prolapse
Sacrocolpopexy With Posterior Repair Obstructed Defecation Symptoms
Participants who undergo laparoscopic sacrocolpopexy (LSCP) plus posterior repair (PR) will demonstrate greater improvement bowel symptom scores compared to participants who undergo LSCP alone at 3 months postoperatively.
- Trial name
- NCT03658395
- Testing
- Laparoscopic Sacrocolopopexy, Posterior repair
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Oklahoma
Unrecognized Condition
Different Surgical Techniques Used for Prolapse Repair in Elderly Patient
The investigator aimed to compare various pelvic floor repairs in female aged from 70 to 80 years old, to see which procedure in terms of treatment-related complications of SCP, VMR and NTR by comparing the operative and…
- Trial name
- NCT03445442
- Testing
- SCP, NTR, VMR
- Volunteers
- 214 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Quality of Life, Pelvic Organ Prolapse
Does Dexamethasone Administration Improve Recovery In Patients Undergoing Minimally Invasive Sacrocolpopexy?
The primary aim is to evaluate whether standard administration of Dexamethasone at the time of general anesthesia induction at the time of minimally invasive sacrocolpopexy (MISC) would result in improved quality of recovery…
- Conditions
- Quality of Life, Pelvic Organ Prolapse, Prolapses, Vaginal Vault
- Trial name
- NCT03094442
- Testing
- Dexamethasone, Normal saline
- Where
- United States
- Sponsor
- The Cleveland Clinic
Postoperative Pain Score
Single Port Insufflation RCT
The goal of this clinical trial is to learn if decreasing insufflation pressure during minimally invasive single port robotic sacrocolpopexy improved postoperative pain without impacting surgeon intraoperative visualization.
- Trial name
- NCT06990750
- Testing
- 15 mmHg, 12 mmHg
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Chicago
Prolapse, Sacrocolpopexy
Retrospective Data Analysis PelviGYNious/EndoGYNious
The retrospective patient chart review aims to generate additional data to substantiate the safety and performance of EndoGYNious and PelviGYNious.
- Conditions
- Prolapse, Sacrocolpopexy, Pelvic Organ Prolapse (POP)
- Trial name
- NCT06927752
- Testing
- PelviGYNious, EndoGYNious
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- A.M.I. Agency for Medical Innovations GmbH
Prolapse; Female
Barbed-suture Efficiency Study for Sacrocolpopexy
Minimally invasive sacrocolpopexy (SCP) performed laparoscopically or with robotic assistance is associated with improved patient-centered outcomes such as faster recovery times, less pain, less bleeding, and shorter hospital…
- Trial name
- BEST (NCT05760794)
- Testing
- Non-barbed delayed absorbable suture, Barbed delayed absorbable suture
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Wake Forest University Health Sciences
Apical Prolapse
Comparison of the Effectiveness and Learning Curve of Laparoscopic Pectopexy Versus Laparoscopic Sacrocolpopexy
Pelvic organ prolapse, particularly apical prolapse, is a common condition among aging women, and laparoscopic sacrocolpopexy is considered the standard surgical treatment due to its high anatomical success.
- Trial name
- NCT07596498
- Testing
- Laparoscopic Pectopexy, Laparoscopic Sacrocolpopexy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University