Clinical trials: Sarcopenia
Health Literacy, Middle Aged
Health Literacy-Based Multifactorial Program for Adults With Sarcopenia
Sarcopenia is a common age-related condition characterized by the progressive loss of muscle mass and function, which may lead to reduced physical performance, disability, and poorer quality of life.
- Conditions
- Health Literacy, Middle Aged, Elderly (People Aged 65 or More), Exercise Therapy
- Trial name
- NCT07654478
- Testing
- Multicomponent Intervention
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Hospital
Aging, Sarcopenia
Effects of Whole-body Electrical Muscle Stimulation Exercise on Spinal Motoneuronal Activation in Older Adults
During this pilot study, the investigators will examine the effects of whole-body electrical muscle stimulation exercise (WB-EMS Exercise) on motoneuronal activation in healthy adults, which typically decreases with age.
- Conditions
- Aging, Sarcopenia, Sarcopenia in Elderly
- Trial name
- NCT06689618
- Testing
- Exercise
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Possible Sarcopenia
Exercise Snacks for Muscle Strength in Older Adults With Possible Sarcopenia
This study aims to investigate whether exercise snacks, a time-efficient approach involving short bouts of exercise performed throughout the day, can improve muscle strength in older adults with possible sarcopenia.
- Trial name
- NCT07821164
- Testing
- Exercise Snacks, Home-based Resistance Training
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ziren Zhao
Sarcopenia
Linking Diet, Inflammation, Gut Microbiota, and Sarcopenia: A Cross-Sectional Study
Based on the analysis of dietary characteristics, gut microbiota diversity, and composition, this study investigates the relationships between the dietary inflammatory potential, gut microbiota, and sarcopenia.
- Trial name
- NCT07211321
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 1,220 people, healthy volunteers welcome
- Sponsor
- Jianhua Ma
Sarcopenia, Frailty
Sarcopenia Prevention With a Targeted Exercise and Protein Supplementation Program
Physical inactivity and protein malnutrition have been implicated to be key and modifiable causes of enhanced muscle mass loss among seniors.
- Conditions
- Sarcopenia, Frailty, Malnutrition; Protein, Fall
- Trial name
- STRONG (NCT03417531)
- Testing
- Protein Supplement, Protein-free Supplement, Active Exercise
- Where
- 2 sites in Switzerland
- Volunteers
- 801 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Sarcopenia
Creatine-Guanidinoacetic Acid Supplementation for Sarcopenia (CREGAAS)
Sarcopenia-driven brain and muscle creatine deficit could be seen as a distinctive pathological facet of this condition, and this might be approached with targeted therapies in aim to restore creatine homeostasis in target…
- Trial name
- CREGAAS (NCT04652921)
- Testing
- Creatine-guanidinoacetic acid, Inulin
- Where
- Serbia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Novi Sad, Faculty of Sport and Physical Education
Chronic Metabolic Disorder, Lipid Metabolism Disorders
Randomized Clinical Trial of HMR(Home Meal Replacement)-Type Omega-3-balanced-diet
Investigate whether HMR(Home meal replacement)-type omega-3-balanced-diet can improve clinical laboratory values related to chronic metabolic diseases through reducing lipids and chronic inflammation, and can prevent muscle loss.
- Conditions
- Chronic Metabolic Disorder, Lipid Metabolism Disorders, Sarcopenia
- Trial name
- NCT04552574
- Testing
- HMR(Home meal replacement)-type omega-3-balanced diet
- Where
- South Korea
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Chungbuk National University Hospital
Aging, Muscular Atrophy
Maximizing Mechanisms of Muscle Hypertrophy to Combat Sarcopenia in Older Adults
Resistance training has shown the most promise among interventions aimed to combat aging muscle atrophy as it enhances strength, power, and mobility function, but induces varying degrees of skeletal muscle hypertrophy as the…
- Trial name
- NCT02442479
- Testing
- resistance training
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Sarcopenia, Osteoporosis
The Effect of Bovine Colostrum Supplementation in Older Adults
Bovine colostrum is the initial milk secreted by cows during the first day after calving. Colostrum is high in protein and contains a number of substances that have potential to be beneficial for the immune system.
- Trial name
- NCT01792297
- Testing
- Bovine colostrum, Whey protein
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Aging, Sarcopenia
Assessing the Impact of Age, and a Short-term High-intensity Interval Training (HIIT) on Skeletal Muscle Mass and Mitochondrial Activity
The goal of this interventional study is to learn about the role of mitochondrial function in healthy aging, and then go on and assess the role of a home-based exercise program on the changes seen.
- Trial name
- Mi-HIIT (NCT05934760)
- Testing
- High intensity interval training (HIIT), Resistance based training (RET)
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Sarcopenia
Effect of Nutrition Supplementation Combined With Resistance Exercise in Elderly With Sarcopenia.
The purpose of this study was determine whether milk or soy milk supplements combined with resistance exercise improved sarcopenia in the elderly.
- Trial name
- NCT05035121
- Testing
- milk supplement, soy milk supplement, resistance exercise
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Sarcopenia
Assessing the Dose-response of Muscle Protein Synthesis to "Super-whey" in Older Adults
Skeletal muscle accounts for approximately 45-55% of total body mass in healthy adults and plays a pivotal role in whole-body metabolic health, locomotion and physical independence.
- Trial name
- ARLA-WHEY (NCT05700058)
- Testing
- Dietary protein supplement
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Sarcopenia, Healthy Elderly
Exercise and Nutritional Supplementation
To understand the effects of a novel dietary supplement when used in conjunction with a healthy lifestyle exercise program and to define biomarkers that are specific to sarcopenia.
- Conditions
- Sarcopenia, Healthy Elderly, Healthy Young
- Trial name
- ENSASL (NCT03536871)
- Testing
- multi-nutrient supplement, Exercise
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- McMaster University
Sarcopenia
Nutritional Intervention for Sarcopenia
Sarcopenia is an age-related poor healthy outcome. nutrition intervention is one , progressive, generalized loss of muscle mass and the decrement in physical activity.
- Trial name
- NCT03891134
- Testing
- Branched Chain Amino Acid
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- Chimei Medical Center
Muscle Atrophy, Age-Related Sarcopenia
Impacts of Mechanistic Target of Rapamycin (mTOR) Inhibition on Aged Human Muscle (Rapamune)
As people age, muscle mass and function is lost and exercise training is an important way to reduce the effects of this and remain independent.
- Trial name
- Rapamune (NCT05414292)
- Testing
- Rapamune (sirolimus) 1Mg Tablet, Unilateral resistance exercise training
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Elderly, Sarcopenia
Early Detection of Disability and Health Promotion for Community-dwelling Elderly
This study evaluates the effects of exercise intervention on muscle strength and walking speed for the community-dwelling elderly.
- Trial name
- NCT03607136
- Testing
- exercise training
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
Sarcopenia, Frailty
Muscle Biopsies in Healthy Volunteers
Background: In individuals as they age, changes in muscle tissue can significantly affect their muscle strength and exercise endurance.
- Conditions
- Sarcopenia, Frailty, Aging
- Trial name
- NCT01431677
- Testing
- Muscle Biopsy
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Activities of Daily Living, Functional Fitness
Vitality Acupunch Exercise Program for Sarcopenia Older Adults
This project was aimed to test the effects of a six-month VA program on the activities of daily living (ADL) and functional fitness of institutional older adults with sarcopenia.
- Trial name
- VA (NCT04504786)
- Testing
- Vitality acupunch (VA) exercise program, Control
- Where
- Taiwan
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University
Sarcopenia, Aging
The Study of Sarcopenia and Aging Biomarkers by the Metabolomics
With the rapid growth of the global elderly population, the studies of the biomarkers of the sarcopenia and aging are under investigation in different ways.
- Trial name
- NCT03121326
- Testing
- blood and urine sampling
- Where
- Taiwan
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Elderly, Metabolic Syndrome
Metabolic Syndrome and Vitamin D Level in Old People
In 2012, a cross-sectional survey sampling 1,966 community-dwelling old people was conducted. Structurized questionnaires were interviewed face-to-face by well-trained staffs.
- Conditions
- Elderly, Metabolic Syndrome, Vitamin D Deficiency, Ostreocalcin
- Trial name
- NCT03344718
- Where
- Taiwan
- Volunteers
- 549 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital