Clinical trials: Satiety and Appetite
Lack of Satiety, Hyperphagia
The Impact of Snacks Which Vary Nutritionally in Their Satiating Potential on Measures of Appetite Control
The current study will examine the effect of almond consumption (0.9g/kg dose) compared to an energy and weight matched comparator food or no food on measures of appetite control including appetite sensations, energy intake and…
- Trial name
- NCT02480582
- Testing
- Almonds, Cheese Savouries
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Obesity
Acute Effects of SATIOSTAT Ingestion on Satiation Hormones, Gastric Emptying, Subjective Feelings of Appetite and Energy Intake
SATIOSTAT is a composition comprising a specific dietary fibre component (a mixture of hydrocolloids with excellent safety profiles and a long history of use in humans) and a lipid component (long-chain fatty acids).
- Trial name
- NCT02956356
- Testing
- Control treatment + oral glucose, SATIOSTAT treatment + oral glucose, Control treatment + meal intake
- Where
- Switzerland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Obesity
Positive Energy I Through Overfeeding
The purpose of this trial is to examine the metabolic and behavioral effects of a positive energy balance induced by adding food to the usual level of activity.
- Trial name
- NCT01653145
- Testing
- Diet A, Diet B, Diet C
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Diabetes Mellitus
Insulin Detemir Compared to Insulin Glargine: Appetite and Calories Consumed in Type 1 Diabetes
Patients with diabetes treated with insulin often gain weight, which may deter patients from adhering to insulin treatment. Detemir is one type of long acting insulin approved by the Food and Drug Administration for use in people…
- Trial name
- NCT00659165
- Testing
- Insulin Detemir, Insulin Glargine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of New Mexico
Overweight, Weight Loss
Study to Evaluate Benefit of ProbioSatys™ on Weight Reduction in Overweight Subjects
The study aims to evaluate the effects of ProbioSatys™ on body weight and related parameters in overweight subjects during a 12-week consumption period. In addition, tolerability and safety of ProbioSatys™ will be assessed.
- Trial name
- NCT03657186
- Testing
- ProbioSatys™
- Where
- 3 sites in Germany
- Volunteers
- 236 people
- Sponsor
- TargEDys
Glycemic Response
Avocado Fruit on Postprandial Markers of the Glycemic Response, Satiety/Appetite and Cardiometabolic Risk
The primary goal is to characterize the acute effects of avocado intake on glycemic and satiety/ appetite responses in relatively healthy overweight / obese adults.
- Trial name
- AVOC1 (NCT02479048)
- Testing
- Test meal 1, Test meal 2, Control Meal (CM)
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Diet Induced Thermogenesis
Effect of Allulose on Diet-induced Thermogenesis
The objective of this study is to investigate the dose-response effect of allulose on diet-induced thermogenesis, substrate oxidation, glycemic response, and subjective appetite in healthy normal weight adults.
- Trial name
- NCT06515340
- Testing
- Allulose Dose 1, Allulose Dose 2, Allulose Dose 3
- Where
- Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
Insulin Resistance, Hyperinsulinism
To Compare the Effects of Non-nutritive Sweeteners Intake in Woman With Insulin Resistance
ABSTRACT Introduction: There is no current data about the effects of non-nutritive sweeteners (NNS) about important factors, such as the energy intake, appetite and its relationship in people with insulin resistance when tasting…
- Trial name
- NCT04327245
- Testing
- Intervention ingest a 5000 mg of D-tagatose, Intervention ingest a 15,3 mg of stevia
- Volunteers
- 33 people
- Sponsor
- University of Chile
Eating Behavior
Effects of Low Calorie Sweeteners on Dietary Intakes, Hunger, Appetite and Satiety
Although there is evidence that low calorie sweeteners (LCS) do not stimulate hunger or appetite, divergent opinions appear regularly both in the scientific literature and in the popular press.
- Trial name
- NCT02297880
- Testing
- Beverage containing low calorie sweeteners, Still water
- Where
- France
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- The Coca-Cola Company
Food Selection
Satiety Effects of the Combination of Egg and Whole Grains
The satiety effects of the combination of protein and fiber within egg and whole grain breakfast meals. High protein with low and high-fiber is hypothesized to be more satiating than low protein, low fiber.
- Trial name
- NCT02272153
- Testing
- Egg refined grain, Egg Whole Grain, Cereal Refined grain
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Healthy Volunteers
Evaluation of Glycemic Index, Glycemic Load and Insulinemic Index of Spanish Breads
The present study was carried out to determine the glycaemic index (GI), glycaemic load (GL), insulinaemic index (InI), appetite ratings and postprandial plasma concentrations of gastrointestinal hormones related to the control…
- Trial name
- BREADGI (NCT02297074)
- Testing
- Ordinary white bread, Precooked-Frozen White Bread, Candeal-flour White Bread
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Organización Interprofesional Agroalimentaria de Cereales Panificables y Derivados
Healthy
Effect of Herbs and Spices on Metabolic Regulation and Appetite in Healthy Subjects
The purpose of the study is to investigate how herbs and spices affect acute/postprandial glucose and insulin responses, inflammatory markers, appetite control peptides, antioxidative capacity, as well as subjective appetite…
- Trial name
- AFC-SPICES (NCT02035241)
- Testing
- Spices 1, Spices 2, Spices 3
- Where
- Sweden
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Lund University
Obesity, Food Craving
Transcranial Magnetic Stimulation (TMS) in Obesity
Obesity is a metabolic disease that has reached epidemic proportions. Insofar no long-term effective drug treatment was developed for obesity.
- Conditions
- Obesity, Food Craving, Appetite and General Nutritional Disorders
- Trial name
- NCT03009695
- Testing
- High frequency repetitive dTMS, Low frequency repetitive dTMS
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Ospedale San Donato
Microbial Colonization, Metabolic Syndrome
Effects of Pulse Consumption, Gut Microbiome, and Appetite in Healthy Participants
The purpose of the study is to investigate the effects of pulse consumption versus no pulse consumption on the gut microbiome, meal satiety, and short-chain fatty acid metabolomics.
- Trial name
- PULSE (NCT07043712)
- Testing
- High pulse consumption
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Obesity
Safety and Efficacy of APD356 in the Treatment of Obesity
This is a research study of an investigational drug, APD356, a novel, selective 5-HT2c receptor agonist, in clinical development as a potential treatment for obesity.
- Trial name
- NCT00116740
- Testing
- APD356
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
Body Weight, Non-restrained Eaters
Appetite Suppression Trial With Polydextrose
Overweight and obesity are a global epidemic, which causes a rapid increase in the frequency of diabetes and cardiovascular diseases.
- Trial name
- NCT02064205
- Testing
- 12.5 g polydextrose, glucose syrup
- Where
- Netherlands
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- W.J. Pasman
Appetite and General Nutritional Disorders
The Effects of Whey, Rice and Potato pRotein isOlates on appeTite rEgulatIoN in Healthy Men
INTRODUCTION: Global protein consumption has been increasing for decades due to changes in socio-economic demographics and consumer trends towards higher protein intake, which may be related to their health benefits in…
- Trial name
- PROTEIN (NCT04876495)
- Testing
- Whey protein isolate, Potato protein isolate, Rice protein isolate
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Westminster
Body Weight, Appetitive Behavior
High Fat vs High Protein and Appetite Hormones
This study will investigate the effects of high-protein, high-fat snacks, specifically Greek yogurt, and peanuts, on satiety, gut hormones, and insulin secretion in overweight and obese women.
- Conditions
- Body Weight, Appetitive Behavior, Dietary Exposure, Hormone Deficiency
- Trial name
- NCT04518930
- Testing
- Peanuts or plain Greek yogurt
- Where
- Jordan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Al-Balqa Applied University
Overweight, Obesity
Chronic Effects of Fats on Satiety & Energy Needs
The purpose of this study is to evaluate the effect of dietary fat on satiety (the experience of fullness between one meal and the next) and energy metabolism over an extended period of time (chronic effects).
- Trial name
- NCT03236181
- Testing
- SFA, MUFA, PUFA
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Snacking
The Effects of Snack Size and Variety on Appetite Control, Satiety, and Eating Behavior in Healthy Adults.
The investigators propose a randomized snack study in normal to obese adults that will test whether snack size, choice, or variety has an influence on daily snack intake.
- Trial name
- NCT03940105
- Testing
- Packout
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Purdue University