Clinical trials: Scarring Alopecia
Fibrosing Alopecia, Frontal Fibrosing Alopecia
Follicular Revival in Fibrosing Alopecia: Evaluating Use of Micro-needling
To evaluate the efficacy microneedling via a professional tattoo machine in revitalizing hair follicles in patients with fibrosing alopecia.
- Conditions
- Fibrosing Alopecia, Frontal Fibrosing Alopecia, Central Centrifugal Cicatricial Alopecia
- Trial name
- NCT04342091
- Testing
- SOL Nova Device
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Yale University
Hair Transplantation
Fractional CO₂ Laser Before Follicular Unit Extraction Hair Transplantation With Platelet-Rich Plasma for Secondary Cicatricial Alopecia
Secondary cicatricial alopecia is characterized by permanent hair loss due to destruction of hair follicles following trauma, burns, infection, or other causes.
- Trial name
- CO2-FUE-PRP (NCT07751523)
- Testing
- hair transplantation preceded by fractional and PRP
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Tanta University
Scarring Alopecia, Androgenetic Alopecia
1470nm Laser for the Treatment of Androgenetic Alopecia and Scarring Alopecia
Single-center, open-label, baseline-controlled, pilot study evaluating the use of a Nonablative 1470 nm laser for the treatment of androgenetic alopecia and scarring alopecia.
- Trial name
- NCT05460611
- Testing
- Sciton HALO 1470nm Non-ablative laser
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Central Centrifugal Cicatricial Alopecia
A Study of Revian Red All LED Cap as a Novel Treatment for Central Centrifugal Cicatricial Alopecia
The purpose of this study is to determine if the Revian Red All LED cap shows potential to be an effective treatment for Central centrifugal cicatricial alopecia (CCCA) by recruiting hair follicles back to anagen growth or by…
- Trial name
- NCT05759338
- Testing
- Revian Red All LED cap
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Wake Forest University Health Sciences
Androgenetic Alopecia, Cicatricial Alopecia
Evidence-Based Integrated Protocol to Maximize Hair Follicle Survival in Follicular Unit Extraction (FUE)
Follicular unit extraction (FUE) is a widely used surgical technique for hair restoration, yet hair follicle survival rates vary depending on surgical instrumentation, graft handling, and perioperative care.
- Trial name
- NCT07850011
- Testing
- Integrated Evidence-Based FUE Protocol, Standard FUE Practice
- Volunteers
- 30 people
- Sponsor
- Assiut University
Central Centrifugal Cicatricial Alopecia, Frontal Fibrosing Alopecia
Deucravacitinib in the Treatment of Cicatricial Alopecias
This is a prospective, open-label clinical trial, in which all participants will be treated with deucravacitinib for 48 weeks. Approximately 20 participants will be enrolled: 10 Central Centrifugal Cicatricial Alopecia (CCCA) and…
- Trial name
- NCT07508488
- Testing
- Deucravacitinib
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Frontal Fibrosing Alopecia
Study to Assess the Efficacy of Intralesional Corticosteroid on the Treatment of Frontal Fibrosing Alopecia
The purpose of this study is to determine the efficacy of treatment with intralesional injection of corticosteroids on the treatment of Frontal Fibrosing Alopecia (compared with placebo), between three months, six months and…
- Trial name
- FFA (NCT02467101)
- Testing
- Corticosteroid/Saline
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Rubina Alves
Keloid, Alopecia Areata
Pain Outcomes Following Intralesional Corticosteroid Injections
Corticosteroid therapy, including intralesional and topical applications, has many indications within the fields of Dermatology, Plastic Surgery, and Orthopedics.
- Conditions
- Keloid, Alopecia Areata, Acne, Hypertrophic Scar
- Trial name
- NCT03630198
- Testing
- Corticosteroid with lidocaine, Corticosteroid with normal saline
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Central Centrifugal Cicatricial Alopecia (CCCA)
Tirzepatide for Treatment of CCCA
The goal of this pilot clinical trial is to learn if tirzepatide can treat active central centrifugal cicatricial alopecia (CCCA), a type of permanent scarring hair loss, in adults.
- Trial name
- NCT07734870
- Testing
- Tirzepatide
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Hair Diseases, Alopecia
Efficacy and Safety of TargetCool + Benev Exosomes in Patients With Hair Thinning
This clinical trial is testing a new approach to help improve hair thinning using a combination of cosmetic treatments. The purpose of the study is to learn whether applying exosomes to the scalp, along with microneedling and a…
- Conditions
- Hair Diseases, Alopecia, Hair Thinning
- Trial name
- NCT06999408
- Testing
- Scalp tattoo, Canfield HairMetrix®, TargetCool
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Recens Medical, Inc.
Cicatricial Alopecia
Ritlecitinib for Cicatricial Alopecia
Alopecia could be subdivided into two main groups of diseases: non-scarring alopecia, such as male pattern baldness, or alopecia areata (AA), in which hair follicles are preserved, yet quiescent, and scarring alopecia, also known…
- Trial name
- NCT05549934
- Testing
- PF-06651600
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Emma Guttman
Lichen Planopilaris, Cicatricial Alopecia
The Effectiveness of Hydroxychloroquine Versus Methotrexate in the Treatment of Lichen Planopilaris in Routine Clinical Care: a Patient Preference Trial
Rationale Lichen planopilaris (LPP) is a prevalent form of cicatricial alopecia, predominantly affecting women and causing irreversible hair loss.
- Trial name
- HEMLET (NCT06512753)
- Testing
- Hydroxychloroquine, Methotrexate
- Where
- Netherlands
- Volunteers
- 56 people
- Sponsor
- Erasmus Medical Center
Central Centrifugal Cicatricial Alopecia (CCCA)
Study to Determine Effect of Gentle Wounding to Stimulate Hair Follicle Neogenesis
The investigators have extensive evidence in mouse that wounding leads to the generation of new hair follicles in the skin. This can be an important new therapy for patients with scarring, but especially those with alopecia.
- Trial name
- NCT03491267
- Testing
- Retinoic acid, Laser
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Johns Hopkins University
Focal Non-cicatricial Alopecia
Relevance of Trichoscopy in Differential Diagnosis of Focal Non-cicatricial Alopecia in Children
Alopecia is a common, distressing condition that is sometimes difficult to diagnose and treat. Losing hair is not usually health threatening; it can scar a young child's vulnerable self-esteem by causing immense psychological and…
- Trial name
- NCT03260777
- Testing
- Trichoscopy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Cicatricial Alopecia, Lichen Planopilaris
a Retrospective Study on the Systemic Treatment of LPP and FFA
This retrospective study aims to assess the effectiveness of systemic treatments for lichen planopilaris (LPP) and frontal fibrosing alopecia (FFA) in patients treated at the Erasmus MC University Medical Center.
- Conditions
- Cicatricial Alopecia, Lichen Planopilaris, Lichen Plano-Pilaris, Frontal Fibrosing Alopecia
- Trial name
- NCT06512766
- Testing
- Hydroxychloroquine, Methotrexate, Cyclosporine A
- Where
- Netherlands
- Volunteers
- 315 people
- Sponsor
- Erasmus Medical Center
Central Centrifugal Cicatricial Alopecia (CCCA)
Treatment Results for Patients With Central Centrifugal Cicatricial Alopecia (CCCA): a Multicenter Prospective Study
The objective of this study is to examine photos of CCCA patients taken before and after treatment to compare treatment outcomes between different treatment groups
- Trial name
- CCCA (NCT04207931)
- Testing
- Topical steroid class I-II, Triamcinolone Acetonide, Doxycyline
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Wake Forest University Health Sciences
Central Centrifugal Cicatricial Alopecia
Baricitinib for Central Centrifugal Cicatricial Alopecia in Adults of African Descent
This study evaluated the safety and efficacy of baricitinib 4 mg daily in adults of African descent with biopsy-proven central centrifugal cicatricial alopecia, a scarring alopecia for which no FDA-approved treatment exists.
- Trial name
- NCT07843732
- Testing
- Baricitinib
- Where
- 4 sites in United States
- Volunteers
- 27 people
- Sponsor
- Raven Clinical Research
Central Centrifugal Cicatricial Alopecia
Apremilast in the Treatment of Central Centrifugal Cicatricial Alopecia (CCCA)
This is a single-center, open-label clinical study to study the efficacy of apremilast in the treatment of mild to moderate central centrifugal cicatricial alopecia.
- Trial name
- NCT03521687
- Testing
- Apremilast
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Scarring Alopecia, Central Centrifugal Cicatricial Alopecia
Barriers to Care and QOL for CCCA Patients
The purpose of the current project is twofold; first to determine what personal, historical, logistical, and environmental factors preclude women from obtaining medical care for CCCA hair loss.
- Conditions
- Scarring Alopecia, Central Centrifugal Cicatricial Alopecia, Central Centrifugal Scarring Alopecia
- Trial name
- NCT03044782
- Testing
- 53-Item Survey
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Scarring Alopecia, Frontal Fibrosing Alopecia
Role of Neurogenic Inflammation and Topical 6% Gabapentin Therapy in Symptomatic Scarring Alopecia
This study will serve as a pilot study to determine the efficacy and safety of topical gabapentin in the treatment of symptomatic scarring alopecia.
- Conditions
- Scarring Alopecia, Frontal Fibrosing Alopecia, Lichen Planopilaris, Central Centrifugal Cicatricial Alopecia
- Trial name
- NCT03346668
- Testing
- Topical gabapentin
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Minnesota