Clinical trials: Scars
Cesarean Section Complications
Assessment of the Impact of Soft Tissue Mobilization on the Scar in Patients After Cesarean Section
The aim of the study is to assess the impact of soft tissue mobilization on the scar in patients after cesarean section. An additional aim is to assess the relationship between the initial stiffness and elasticity of the scar and…
- Trial name
- NCT06446258
- Testing
- Manual therapy (myofascial release, soft tissue mobilization)
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nicolaus Copernicus University
Low Back Pain, Pelvic Pain
Physical Therapy in Addition to Standard Care Following C-Section
The purpose of this study is to determine whether a physical therapy program which includes scar management, core retraining, and lumbar and pelvic joint mobilization will significantly impact the postpartum recovery following…
- Conditions
- Low Back Pain, Pelvic Pain, Scar Tissue, Adhesions
- Trial name
- NCT02804139
- Testing
- Standard care plus physical therapy, Standard Care
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Atrophic Acne Scar
SkinPen Efficacy on Acne Scars on the Face and/or Back
This single-center, clinical trial will take place over a 90 day course followed by 1-month and 6-month post treatment visits to assess the efficacy and tolerability of the SkinPen device when used on both men and women on the…
- Trial name
- NCT02646917
- Testing
- Aesthetic Microneedling Treatment
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Bellus Medical, LLC
Scarring Alopecia, Central Centrifugal Cicatricial Alopecia
Barriers to Care and QOL for CCCA Patients
The purpose of the current project is twofold; first to determine what personal, historical, logistical, and environmental factors preclude women from obtaining medical care for CCCA hair loss.
- Conditions
- Scarring Alopecia, Central Centrifugal Cicatricial Alopecia, Central Centrifugal Scarring Alopecia
- Trial name
- NCT03044782
- Testing
- 53-Item Survey
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Burn Scar Contraction
Perforator Based Interposition Plasty
Objective: to evaluate the perforator based interposition plasty in comparison to the standard technique (full thickness graft) for scar contracture releases. Study design: A randomised controlled multicentre intervention study.
- Trial name
- NCT01409759
- Testing
- Perforator based interposition flap
- Where
- 3 sites in Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Association of Dutch Burn Centres
Vitiligo, Depigmented Scars
Comparative Study Using Dermabrasion vs CO2 Laser & Collagen Dressing vs Vaseline Gauze in MKTP
The purpose of this study is to: 1. Compare two different techniques in the melanocyte keratinocyte transplant procedure: Use of carbon dioxide laser versus use of dermabrasion 2.
- Conditions
- Vitiligo, Depigmented Scars, Depigmentation
- Trial name
- MKTP (NCT02038257)
- Testing
- MKTP (melanocyte keratinocyte transplant procedure), Collagen Dressing, Vaseline Impregnated Gauze
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Cicatrix, Scar Prevention
Evaluation of the Safety, Pharmacokinetics, and Preliminary Effect on Scar Formation by RXI-109
The primary purpose of this study is to evaluate the safety and tolerability of a single intradermal administration of RXI-109 at small surgical incisions in the abdominal skin that will later be removed during an elective…
- Trial name
- NCT01640912
- Testing
- RXI-109
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- RXi Pharmaceuticals, Corp.
Hair Reduction, Tattoo Removal
Clinical Study to Evaluate the Safety and Efficacy of Candela Technology
This is a non-randomized, multi-center, open-label, prospective clinical study evaluating the clinical treatment with Candela Medical Technology.
- Conditions
- Hair Reduction, Tattoo Removal, Wrinkle, Acne
- Trial name
- NCT06202274
- Testing
- Nordlys, Gentle, Picoway, Vbeam, Profound, Profound Matrix, eTwo, Exceed, CO2RE
- Where
- 3 sites in United States, Israel
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Atrophic Acne Scar
A Study to Evaluate the Efficacy of ELAPR002f in Females and Males With Atrophic Acne Scars
The study is designed to evaluate the efficacy of two formulations of a cross-linked tropoelastin matrix given the product codes ELAPR002f (collectively referred to as ELAPR or ELAPR002) for the treatment of rolling atrophic acne…
- Trial name
- NCT03056235
- Testing
- ELAPR002f, Saline
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Elastagen Pty Ltd
Caries Class II
Clinical Performance of Injection-Molding Vs. Incremental Packing of Resin Composite in Cavitated Posterior Teeth
The clinical performance of 2 bonding and composite packing techniques in the proximal cavities of permanent posterior teeth will be assessed.
- Trial name
- NCT05020093
- Testing
- Injection molding, Incremental packing
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cesarean Section Complications
Cesarean Scar Defect (CSD); Prevalence, Risk Factors And Possible Associated Symptoms
The study aims to detect the incidence of Cesarean Scar Defect (CSD) in women undergoing CS in Women Health Hospital (WHH), assiut University, to identify risk factors for development of CSD and identify the possible…
- Trial name
- isthmocele (NCT04605328)
- Testing
- Two dimension and three dimension ultrasound
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cutaneous Leishmaniasis, Scar
Cosmetic Outcome of Leishmaniasis Scar After WR279396 Application
Primary Objectives: Assess whether CL (caused by Leishmaniasis major) lesions treated with WR279396 improved the cosmetic outcome compared with no treatment (natural healing)
- Trial name
- SCAR (NCT00490230)
- Testing
- WR 279396
- Where
- Tunisia
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research and Development Command
Scar Quality Assessment and Safety
A Comparative Study of Scar Quality and Safety According to Suture Materials Following Excision of Benign Tumors
Due to the rise in the incidence of giant benign tumors such as lipoma, excision of benign tumors on body have been performed by plastic surgeons.
- Trial name
- NCT05240820
- Testing
- multi-layer wound closure
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital
Cicatrix, Wound Healing
Investigation Into the Scar Reduction Potential of Prevascar (Interleukin-10)
The purpose of this study was to investigate the scar-reducing properties of eight doses of intradermal Prevascar (IL-10).
- Trial name
- NCT00984646
- Testing
- Prevascar
- Where
- United Kingdom
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Renovo
Scar, Cicatrix
Clinical Safety and Scar Prevention Study of a Topical Antifibrotic Compound FS2.
The study will investigate the safety and effectiveness of daily post surgical scar management, using a moisture-balancing base product containing different amounts of a novel (NCE) antifibrogenic compound FS2, a natural…
- Conditions
- Scar, Cicatrix, Hypertrophic Scar, Skin Graft Scar
- Trial name
- FS2 (NCT04186273)
- Testing
- Fibrosis-Inhibiting-Compound-FS2, Vehicle moisture balancing base
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
CS Scar Defect(Niche) How to Avoid
Incidence of Caesarean Scar Defect in Cases of Cesarean Section With and Without Bladder Flap Dissection
Anatomically Uterine niche is an iatrogenic pouch-like defect at the site of previous caesarean scar due to defective tissue healing.
- Trial name
- NCT06503627
- Testing
- bladder flap dissection
- Where
- Egypt
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Skin Scarring, Eyebrow Ptosis
Use of Botulinum Toxin A in Direct Eyebrow Lift Scar
Prospective, controlled and randomized study in which participants indicated for surgery to direct eyebrow lift will be randomized into two groups.
- Trial name
- NCT06465056
- Testing
- Botulinum toxin type A
- Where
- 2 sites in Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Uterine Scar
Safety of Umbilical Cord Mesenchymal Stem Cell Local Intramuscular Injection for Treatment of Uterine Scars
The purpose of this study is to evaluate the safety of umbilical cord mesenchymal stem cell local intramuscular injection for treatment of uterine scars by a prospective, single-center, open, and single-arm clinical trial.
- Trial name
- NCT03181087
- Testing
- Umbilical cord MSCs
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Maternal and Child Health Hospital of Foshan
Isthmocele, Uterine Scar Defects
Cesarean Scar Defects After Uterine Closure by Double-layer Barbed or Smooth Suture
Late sequelae of a cesarean section related to a uterine scar defects include gynecological symptoms and obstetric complications.
- Conditions
- Isthmocele, Uterine Scar Defects, Cesarean Section Complications, Uterine Niche
- Trial name
- NCT04825821
- Testing
- Clinical and ultrasonographic assessment
- Where
- Italy
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- Ospedale Policlinico San Martino
Keloid, Autologus Adipose Derived Stem Cells
Autologous Adipose Derived Stem Cells Transplantation in the Treatment of Keloids.
Keloids are the most common disfiguring skin disorder affecting colored population with a prevalence of upto 16%. Autologous adipose derived stem cells have been found to have potential therapeutic benefits however limited…
- Conditions
- Keloid, Autologus Adipose Derived Stem Cells, Feasibility, Safety
- Trial name
- NCT04553159
- Testing
- Autologous adipose derived stem cells
- Where
- Uganda
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Makerere University