Clinical trials: Schizophrenia Spectrum
Schizophrenia
The Efficacy and Safety of Quetiapine XR in Patients With Schizophrenia Switched From Other Antipsychotics
Purpose To evaluate the efficacy and safety of once-daily quetiapine extended release (XR) in patients with schizophrenia switched from other antipsychotics which were suboptimal due to insufficient efficacy or insufficient…
- Trial name
- NCT02142556
- Testing
- Administration of quetiapine XR
- Where
- Taiwan
- Volunteers
- 61 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Schizophrenia
PEARL Schizophrenia Maintenance
Lurasidone HCI is a compound that is FDA-approved for the treatment of schizophrenia. This clinical study is designed to test the hypothesis that Lurasidone is effective in the long term maintenance treatment of schizophrenia.
- Trial name
- NCT01435928
- Testing
- Lurasidone
- Where
- 75 sites in United States, France and 5 more
- Volunteers
- 676 people
- Sponsor
- Sumitomo Pharma America, Inc.
Schizophrenia
The Effect of Hawthorn on Lipoprotein Cholesterol Ratio in Schizophrenics With Antipsychotics
Importance: The problems of side effects of metabolic disturbances in schizophrenic patients have been of worldwide concern for some time. Patients with dyslipidemia have an increased risk of cardiovascular diseases.
- Trial name
- NCT03663465
- Testing
- Hawthorn, SGAs
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Calo Psychiatric Center
Schizophrenia
Efficacy and Safety Study of Aripiprazole to Treat Schizophrenia
This study design is subject to relevant SFDA regulations about clinical trials. Patients will be screened for inclusion into the study at the initial visit(240 patients to be recruited) and then undergo a minimum of 3-7 day's…
- Trial name
- NCT00202007
- Testing
- Aripiprazole tablet, 5-30mg/day, oral, 6 weeks, Risperidone tablet, 1-6mg/day, oral, 6 weeks
- Where
- 6 sites in China
- Volunteers
- 240 people
- Sponsor
- Otsuka Beijing Research Institute
Schizophrenia, Schizoaffective Disorder
Targeting Physical Health in Schizophrenia: Physical Activity Can Enhance Life Randomized Control Trial
Purpose: To test the effectiveness of an exercise intervention that combines group walking, activity tracking, and heart rate monitoring (i.e.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Brief Psychotic Disorder, Schizophreniform Disorders
- Trial name
- (PACE-life (NCT04173572)
- Testing
- PACE-Life, Exercise Intervention
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of North Carolina, Chapel Hill
Psychosis
Online Yoga and the Impact on Psychosis
Yoga and mindfulness are considered complementary and alternative healthcare options that involve breathing techniques, relaxation, and bodily postures (yoga only).
- Trial name
- NCT05046912
- Testing
- Yoga, Mindfulness
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- The Royal Ottawa Mental Health Centre
Schizophrenia
Aripiprazole, Abilify Maintena Collaborative Clinical Protocol
An Open-label, Multi-center, Longitudinal, Within-subject Comparison Study to Evaluate the Effects of Aripiprazole Once Monthly in Subjects with Schizophrenia on 30-, 90-, and 180- day Re-hospitalization Rates Following Hospital…
- Trial name
- NCT02717130
- Testing
- Aripiprazole
- Where
- 4 sites in United States
- Volunteers
- 9 people
- Sponsor
- Florida Atlantic University
Schizophrenia
The Effects of Varenicline on Cognitive Function in Patients With Schizophrenia
The primary objective of this project is to examine the effects of varenicline treatment used concomitantly with antipsychotic medications, on cognitive dysfunction in people with schizophrenia.
- Trial name
- NCT00523445
- Testing
- Varenicline(Chantix)
- Where
- 5 sites in South Korea
- Volunteers
- 120 people
- Sponsor
- Inje University
Schizophrenia Spectrum Disorders, Social Cognition
Using Illusions to Boost Social Cognition
This study aims to explore whether the observation of complex visual objects can help improve social cognition in people living with psychotic disorders.
- Trial name
- SOLLUSIONS (NCT07602712)
- Testing
- Visual-illusion social cognition session (immediate), Visual-illusion social cognition session (delayed)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Hôpital le Vinatier
Psychotic Disorders
Longitudinal Multimodal Neuroimaging Studies in Patients With First Episode Psychosis
The purpose of this study is to investigate the structural, functional and chemical brain abnormalities in patients with first episode psychosis and assess the evolution of these abnormalities during the course of the disease.
- Trial name
- NCT01688765
- Testing
- Observational
- Where
- United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Psychotic Disorders
Critical Time Intervention in the Transition From Hospital to Community in People With Severe Mental Illness
This study will evaluate the effectiveness of a psychosocial treatment, Critical Time Intervention, in easing the transition from hospital to community in people with severe mental disorders.
- Trial name
- NCT00621465
- Testing
- Critical Time Intervention (CTI), Usual care
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- New York State Psychiatric Institute
Delusions, Schizophrenia
Metacognitive Training in Schizophrenia
Over a period of 4 weeks, metacognitive training for schizophrenia patients (MCT), delivered both in a group and individually, is compared to cognitive remediation (CogPack training).
- Trial name
- MCT (NCT01029067)
- Testing
- Metacognitive training, Cognitive Remediation
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Depression, Schizophrenia
Norwegian Adult Mental Health Registry
"The Norwegian Adult Mental Health Registry" (NAMHR) is a medical quality register collecting and systematizing data on patients and their treatment in specialist mental health care for adults in Norway.
- Conditions
- Depression, Schizophrenia, Bipolar Disorder, Eating Disorders
- Trial name
- NAMHR (NCT06115200)
- Volunteers
- 150,000 people
- Sponsor
- Helse Stavanger HF
Schizophrenia
Efficacy of Pimozide Augmentation for Clozapine Partial Response
This is a 12 week outpatient study for patients with schizophrenia who are on Clozapine, but continue to experience symptoms. The purpose of this project is to find out if small doses of pimozide (an antipsychotic medication…
- Trial name
- NCT00374244
- Testing
- Pimozide
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Yale University
Schizophrenic Disorders, Schizoaffective Disorder
Open-Label Study of Intramuscular Olanzapine Depot in Patients With Schizophrenia or Schizoaffective Disorder
This is a long-term, open-label clinical study designed to enable longer-term treatment of patients completing other clinical studies with intramuscular olanzapine depot.
- Trial name
- NCT00088465
- Testing
- Intramuscular olanzapine depot
- Where
- 92 sites in United States, Argentina and 23 more
- Volunteers
- 931 people
- Sponsor
- Eli Lilly and Company
Schizophrenia
Safety and Efficacy of Zicronapine in Patients With Schizophrenia
To assess the effect of zicronapine versus risperidone on metabolic parameters comprising body weight, body mass index (BMI), waist circumference, levels of fasting blood lipids and glucose during 6 months of treatment.
- Trial name
- NCT01295372
- Testing
- Zicronapine, Risperidone
- Where
- 24 sites in Czechia, Estonia and 3 more
- Volunteers
- 160 people
- Sponsor
- H. Lundbeck A/S
Common Mental Disorder
Definitive Selection of Neuroimaging Biomarkers for the Diagnosis and Treatment to Common Mental Disorders
To explore the whole-brain anatomical and functional abnormalities in drug-naive patients with schizophrenia ,drug-naive patients with BD, drug-naive patients with MDD and healthy controls by using a combination of…
- Trial name
- NCT04218981
- Testing
- Antipsychotic drugs, Mood stabilizer, Paroxetine
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Central South University
Schizophrenia
eMotiph: E-mental Health Solution for Patients With Schizophrenia
Although the main objective of current schizophrenia intervention programs is the reduction of symptoms, its rates are around 36%, and recovery rates are 16.5%.
- Trial name
- NCT05345977
- Testing
- eMotiph
- Where
- Spain
- Volunteers
- 7 people
- Sponsor
- Grupo Pulso
Depression, Bipolar Disorder
Just Do You Program for Young Adults With Serious Mental IIlness
Just Do You is a young-adult-centered and theoretically guided intervention that has shown promise for keeping young adults connected to their professional treatments, while also enhancing their hope for the future and their own…
- Conditions
- Depression, Bipolar Disorder, Psychosis, Anxiety Disorders
- Trial name
- NCT03423212
- Testing
- Just Do You, Active Control
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- New York University
Schizophrenia
Effectiveness of Using Calligraphic Activity to People With Schizophrenia
To examine the effects of calligraphy activity on symptoms, attention, emotion, and quality of life in people with schizophrenia.
- Trial name
- NCT03882619
- Testing
- Calligraphy
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- The Hong Kong Polytechnic University