Clinical trials: Schizophrenic Patients
Schizophrenia, Schizo-Affective Disorder
Determining Efficacy and Safety of BXCL501 in Agitation Associated With Pediatric Schizophrenia and Bipolar Disorder
This is a study of the efficacy and safety of BXCL501 in children and adolescents with acute agitation and either bipolar disorder or schizophrenia.
- Conditions
- Schizophrenia, Schizo-Affective Disorder, Schizophreniform; Schizophrenic, Bipolar Disorder I
- Trial name
- NCT05025605
- Testing
- BXCL501 80 Micrograms, BXCL501 120 Micrograms, BXCL501 60 Micrograms
- Where
- 5 sites in United States
- Volunteers
- 140 people
- Sponsor
- BioXcel Therapeutics Inc
Schizophrenia, Negative Type; Schizophrenic
Using Transcranial Magnetic Stimulation (TMS) to Understand 'Negative' Symptoms of Schizophrenia
The main purpose of this study is to learn how transcranial magnetic stimulation (TMS) helps improve negative symptoms of schizophrenia.
- Conditions
- Schizophrenia, Negative Type; Schizophrenic, Schizo Affective Disorder
- Trial name
- NCT03648268
- Testing
- repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Beth Israel Deaconess Medical Center
Patient With Schizophrenia Spectrum Disorder, NLM Classification WM 203, Psychology:Schizophrenic Psychology
Study Comparing Antipsychotic Dose Reduction vs. Maintenance Treatment in Patients With Schizophrenia Spectrum Disorder: a Personalized Medicine Approach
The objective of this study is to respond to frequent requests from patients who wish to reduce or even stop their antipsychotic treatment once they have achieved clinical stability.
- Conditions
- Patient With Schizophrenia Spectrum Disorder, NLM Classification WM 203, Psychology:Schizophrenic Psychology, Schizophrenia Spectrum and Other Psychotic Disorders
- Trial name
- DREAMS-Phen (NCT07152184)
- Testing
- Use of antipsychotic treatment with marketing authorization at doses lower than those recommended: - Olanzapine - Zuclopenthixol - Risperidone - Pipotiazine palmitate / Pipotiazine - Quetiapine - Flup
- Volunteers
- 288 people
- Sponsor
- University Hospital, Strasbourg, France
Tobacco Smoking in Schizophrenic Patients
Antismoking Effects of Electronic Cigarettes in Subjects With Schizophrenia and Their Potential Influence on Cognitive Functioning.
It is well established in studies across several countries that tobacco smoking is more prevalent among schizophrenic patients than the general population.
- Trial name
- SCARIS (NCT01979796)
- Testing
- Ecig 24 mg nicotine, Ecig 0 mg nicotine, Nicotine free inhalator
- Sponsor
- University of Catania
Auditory Hallucinations in Patients With Schizophrenic Disorders
High Frequency Repetitive Transcranial Magnetic Stimulation (rTMS) in Schizophrenia : a Randomized Controlled Study
Background: Repetitive transcranial magnetic stimulation (rTMS) is a recent therapeutic which has demonstrated its efficacy in the treatment of auditory hallucinations in patients with schizophrenic disorders.
- Trial name
- TMS-Hz (NCT01022489)
- Testing
- Transcranial magnetic stimulation: rTMS
- Where
- France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Caen
Psychosis;Schizophrenic
Seven-step Phenomenological Psychotherapy for Self-disorder - a Pilot Study
The goal of this clinical pilot study is to learn how adults with schizophrenia or other non-affective psychotic disorders or psychosis risk syndromes experience a novel psychotherapeutic treatment for self-disorders.
- Trial name
- SSPP-SD-p (NCT06597864)
- Testing
- Seven-step phenomenological psychotherapy for self-disorders
- Where
- 2 sites in Norway
- Volunteers
- 8 people
- Sponsor
- Oslo University Hospital
Suicidal Behavior, Schizophrenic Patients
Suicidal Behavior Among Schizophrenic Patients
This study aimed to; - 1. Study suicidal behavior among sample of schizophrenic patients. 2. Study relation between schizophrenic symptoms and suicidal behavior. 3.
- Trial name
- NCT07145840
- Testing
- Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Schizophrenic Psychoses, Schizophrenia
Implementation of a Tool for Reduction of Cardiovascular Risk in Patients with Severe Mental Disorders ( HEALTHYHEART )
Observational study of the implementation of a Norwegian adaptation of a tool for monitoring, detection and intervention of cardiovascular risk factors in severe mental disorders.
- Conditions
- Schizophrenic Psychoses, Schizophrenia, Severe Mental Disorder
- Trial name
- HEALTHYHEART (NCT06807242)
- Where
- Norway
- Volunteers
- 270 people
- Sponsor
- Oslo University Hospital
Schizophrenic Patients
Effects of tES Combined With Retrieval Practice on Semantic Memory in Patients With Schizophrenia
The semantic processing deficit stands as a central feature of cognitive abnormalities in schizophrenia. Both transcranial electrical stimulation (tES) and retrieval practice have been demonstrated as external techniques capable…
- Trial name
- NCT06547996
- Testing
- tES-tDCS group, tES-tACS group
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Northeast Normal University
Post-Schizophrenic Depression
Low Dose Amisulpride Vs Olanzapine-Fluoxetine Combination in Post-Schizophrenic Depression
Post-Schizophrenic Depression (PSD) increases the morbidity and mortality of Schizophrenic patients. Hence, it warrants early assessment and intervention. But, clinical trials on PSD are very few.
- Trial name
- PSD-AOFC (NCT04876521)
- Testing
- Amisulpride, Olanzapine-Fluoxetine Combination
- Where
- India
- Volunteers
- 60 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Schizophrenic Disorders
Interest of EMDR Schizophrenic Disorders
The purpose of this study is to determine the interest of the use of EMDR (Eye Movement Desensitization and Reprocessing) psychotherapy in the management of psychotic disorders, in particular schizophrenic disorders.
- Trial name
- EMDRpsychose (NCT05164289)
- Testing
- Control group, EMDR group
- Where
- 2 sites in France
- Volunteers
- 6 people
- Sponsor
- Hôpital NOVO
Schizophrenic Patients
Effects of tDCS Combined With Retrieval Practice on Semantic Memory in Patients With Schizophrenia
The semantic processing deficit stands as a central feature of cognitive abnormalities in schizophrenia. Both transcranial direct current stimulation (tDCS) and retrieval practice have been demonstrated as external techniques…
- Trial name
- NCT06538259
- Testing
- Transcranial direct current stimulation (tDCS)-anodal group
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Northeast Normal University
Schizophrenic Disorders
Neuropsychological Assessment of Remediation for Cognitive Impairments in Schizophrenia
This study evaluates the effect of a cognitive remediation program on neurocognitive, social cognitive and metacognitive functions designed for patients living with a schizophrenia spectrum disorder.
- Trial name
- NARCIS (NCT04608032)
- Testing
- [Eco-Sz] Ecological Cognitive training program for schizophrenia spectrum disorder, Recovery-Oriented Therapy
- Where
- 2 sites in France
- Volunteers
- 70 people
- Sponsor
- Centre hospitalier de Ville-Evrard, France
Psychosis;Schizophrenic, Personality Disorders
The Impact of the COVID-19 (SARS-CoV-2 Disease) on Psychopathology
The outbreak of the SARS-CoV-2 pandemic may be considered a traumatic phenomenon. In a sample of subjects suffering from different psychiatric disorders, psychopathological status and Post-Traumatic Stress Disorder (PTSD)…
- Conditions
- Psychosis;Schizophrenic, Personality Disorders, Mood Disorders, Anxiety Disorders
- Trial name
- NCT04694482
- Testing
- Psychometric scale administration
- Where
- Italy
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca
Treatment Adherence, Selfcompassion
Relationship Between Self-compassion and Treatment Adherence in Schizophrenic Spectrum Disorders
Treatment adherence is defined by the World Health Organisation (WHO) as the extent to which the patient's history of therapeutic drug-taking coincides with the prescribed treatment.
- Conditions
- Treatment Adherence, Selfcompassion, Schizophrenic Spectrum Disorder
- Trial name
- CompaSchizo (NCT05566015)
- Testing
- questionnaire
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Schizophrenic Disorders
A Study Measuring Effect of LY2140023 (Pomaglumetad Methionil) on Electrocardiographs in Participants With Schizophrenia
This study determined if a single dose of LY2140023 (pomaglumetad methionil) affects the electrical activity in the heart in participants with schizophrenia.
- Trial name
- NCT01606436
- Testing
- LY2140023, Moxifloxacin
- Where
- 8 sites in United States
- Volunteers
- 86 people
- Sponsor
- Denovo Biopharma LLC
Schizophrenic Psychoses
The Effect of Progressive Muscle Relaxation on Psychological Symptoms and Mental Well-Being in Patients With Schizophrenia
Schizophrenia is a mental illness that progresses with delusions or hallucinations, causes changes in interpersonal communication, thoughts and behaviors, continues with recovery and repetitions, and in which the interpretation…
- Trial name
- NCT05324865
- Testing
- Progressive Muscle Relaxation
- Volunteers
- 90 people
- Sponsor
- Hasan Kalyoncu University
Schizophrenic Psychoses
Sustained Attention Abilities in Schizophrenia
Schizophrenia is a psychiatric pathology, which concerns around 1% of adult population. It is characterized by clinical symptoms combining positive and negative symptoms and thinking disorganization.
- Trial name
- ACCRAS (NCT02388607)
- Testing
- measurements
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Schizophrenics
Nonverbal Synchrony, Therapeutic Alliance and Treatment Engagement in First Episode Schizophrenia
The quality of the therapeutic intervention in a first psychotic episode is a major challenge for quality and effectiveness of treatment.
- Trial name
- ASMASS (NCT03917355)
- Testing
- Nonverbal synchrony, therapeutic alliance
- Where
- France
- Volunteers
- 7 people
- Sponsor
- University Hospital, Montpellier
Negative Type; Schizophrenic, Anhedonia
Motive-specific Intervention for Negative Symptoms in Schizophrenia
The aim of this study is to test a therapeutic intervention to reduce negative symptomatic among schizophrenia patients. Since the intervention can take place within an inpatient stay, it is a short intervention.
- Conditions
- Negative Type; Schizophrenic, Anhedonia, Apathy
- Trial name
- MoNSS (NCT04793438)
- Testing
- Motive-specific intervention, Supportive conversations
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich