Clinical trials: Sciatic Nerve Block
Postoperative Pain
Does Ultrasound Improve Procedural Time in the Lateral Popliteal Approach to the Sciatic Nerve in Obese Patients
Ultrasound have been shown to improve the time needed to locate and block nerves in the non obese population. However, its utility is still unknown in the obese population.
- Trial name
- NCT01579747
- Testing
- Ultrasound, Nerve stimulation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of New Mexico
Arterial Occlusive Diseases
Ischemic Pain Control With Analgesic Methods Clinical Trial
This project is one of four components of a thematic project that aims to evaluate the use of ultrasound in regional blocks, called "Use of ultrasound in regional blocks and injections for the treatment of acute and chronic…
- Trial name
- ISCHAEMIC (NCT02841488)
- Testing
- Continuous peripheral sciatic nerve block, Fentanyl, Ropivacaine
- Volunteers
- 56 people
- Sponsor
- University of Sao Paulo General Hospital
Anesthesia, Local, Nerve Block
Protective Nerve Stimulation in Regional Anesthesia
Peripheral nerve blocks can be conducted with ultrasound, electrical nerve stimulation or landmark technique or a combination of this techniques.
- Conditions
- Anesthesia, Local, Nerve Block, Brachial Plexus Block
- Trial name
- ProNerv (NCT03291691)
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Charite University, Berlin, Germany
Postoperative Pain
Effect of a Sciatic Block (SNB) Combined With a Continuous Femoral Block (CFNB) on Pain Scores After Knee Arthroplasty
The purpose of this study is to determine if the addition of a sciatic nerve block (SNB) to a continuous femoral nerve block (CFNB) improves post-operative analgesia after knee arthroplasty.
- Trial name
- NCT01337115
- Testing
- SNB plus CFNB, CFNB
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- Centro Hospitalar do Porto
Bunionectomy, Hallux Valgus
Phase 3, Sciatic Nerve Block With EXPAREL for Subjects Undergoing Bunionectomy
The study is conducted sequentially in two parts. Part A: The purpose is to obtain information on pharmacokinetic (PK) profile, pharmacodynamics (PD), efficacy, safety, and to assess the performance of 266 mg EXPAREL vs 133 mg…
- Trial name
- NCT05157841
- Testing
- Bupivacaine liposome injectable suspension 266 mg, Bupivacaine HCl, Bupivacaine liposome injectable suspension 133 mg
- Where
- 7 sites in United States
- Volunteers
- 185 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Anterior Cruciate Ligament (ACL) Tear
Sciatic Technique Comparison of Nerve Blockade for Pain Control Following Hamstring Autograft Harvest in Adolescents
The purpose of this research is to compare the effect of single-injection sciatic PNB to continuous sciatic PNB on 1) postoperative pain control as measured by self-reported pain scores, pain medication use, and unplanned…
- Trial name
- NCT02947633
- Testing
- Single-injection sciatic PNB, Continuous sciatic PNB
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Nerve Block
Regional Anesthesia for Major Surgery of the Foot. Levobupivacaïne Ropivacaine 0.5% Versus 0.5% in the Sciatic Block Through médiofémorale
Ropivacaine 0.5% and 0.5% in levobupivacaïne are used in regional anesthesia for major surgery of the foot. The literature does not highlight a significant difference in terms of onset of action between these two molecules to…
- Trial name
- SCIALERO (NCT00956709)
- Testing
- levobupivacaïne 0,5 %, ropivacaïne 0,5 %
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Nantes University Hospital
Open Reduction Internal Fixation(ORIF) of Lateral Malleolus
Sciatic Nerve Block for Ankle/Foot Surgeries. A Comparison Between a Premixed Solution of Lidocaine Plus Bupivacaine and Consecutive Infiltration of Lidocaine and Bupivacaine
Regional anaesthesia has become the cornerstone of multimodal analgesia. With the advent of ultrasound guided nerve blocks regional anaesthesia has achieved both greater efficacy and a better safety profile as the injection of…
- Trial name
- NCT01756443
- Testing
- 2% lidocaine/adrenaline and 0.5% bupivacaine
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- Cork University Hospital
Postoperative Pain, Foot Numbness
Ultrasound Guidance Versus Electrical Stimulation for Continuous Popliteal-Sciatic Nerve Blocks
Research study to determine if pain relief following foot and/or ankle surgery is influenced by the technique used to place perineural catheter.
- Trial name
- NCT00876681
- Testing
- Popliteal catheter placed via ultrasound or electrical stimulation
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, San Diego
Total Knee Replacement, Surgery
Ultrasound Guided Obturator Nerve Block for Total Knee Replacement (TKR)
Total Knee Replacement can be performed under the combination of posterior lumbar plexus block plus sciatic nerve block. The investigators can have the same outcome by performing instead of posterior lumbar plexus block more…
- Trial name
- NCT01755117
- Testing
- Sciatic, femoral, obturator nerve blocks, Sciatic nerve block, posterior lumbar plexus block
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Larissa University Hospital
Ankle Ligament Injury，Chronic Ankle Instability，Ankle Arthroscopy
Preop US-Guided Nerve Blocks for Pain & Recovery After Ankle Arthroscopy
This randomized, double-blind controlled trial investigates the effectiveness and potential trade-offs of preoperative ultrasound-guided popliteal sciatic and saphenous nerve blocks in patients undergoing ankle arthroscopy, a…
- Trial name
- NCT07470021
- Testing
- Ultrasound-guided popliteal sciatic and saphenous nerve block
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Osteoarthritis Knee, Postoperative Pain
Echogenic Versus Stimulating Needle and Catheter for Sciatic Blocks
Patients scheduled for total knee replacements and suitable for sciatic nerve block will be randomized to one of 2 groups. Group 1 will have the nerve block performed using a standard Pajunk block needle under ultrasound guidance…
- Trial name
- Echostim1 (NCT01492660)
- Testing
- echogenic needle and catheter, Neurostimulation to position needle and catheter
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Regional Anesthesia Morbidity, Local Anesthetic Drug Adverse Reaction
Plasma Ropivacaine Concentrations After Sciatic Nerve Block in Patients With Chronic Kidney Disease
This prospective observational study aimed to examine the pharmacokinetics of ropivacaine in patients with chronic kidney disease after sciatic nerve block.
- Trial name
- NCT03666845
- Testing
- Sciatic nerve block
- Where
- South Korea
- Volunteers
- 5 people
- Sponsor
- Seoul National University Hospital
Regional Anesthesia, Sciatic Nerve Block
Comparing Through-the-Needle With Suture-Method Catheter Designs for Popliteal Nerve Blocks
Following painful surgical procedures, postoperative analgesia is often provided with a single-injection peripheral nerve block.
- Trial name
- NCT03442036
- Testing
- Suture-Method Technique, Through-the-Needle Technique
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Popliteal Nerve Block, Foot Surgery
Continuous Popliteal Nerve Blocks: Effect of Perineural Catheter Tip Location Relative to the Sciatic Nerve Bifurcation on Postoperative Analgesia
Research study to determine the relationship between perineural catheter tip location relative to the sciatic nerve bifurcation and postoperative analgesia for continuous popliteal nerve blocks.
- Conditions
- Popliteal Nerve Block, Foot Surgery, Ankle Surgery, Popliteal Bifurcation
- Trial name
- NCT01229696
- Testing
- Catheter Placed At Bifurcation, Catheter Placed 5cm Above Bifurcation
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of California, San Diego
Anesthesia, Regional, Anesthesia and Analgesia
Difference in Occurrence of Rebound Pain in Patients Undergoing Surgery Under Popliteal Block or Ankle Block
This is a monocentric, comparative prospective randomized controlled trial. Patients will be randomised into 2 groups and will receive either a sciatic popliteal nerve block or an ankle block (single dose locoregional block…
- Trial name
- CBFR (NCT05734469)
- Testing
- Forefoot bone surgery
- Volunteers
- 90 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Critical Limb Ischemia (CLI), Popliteal Nerve Block
Ultrasound-Guided Sciatic Popliteal Nerve Block vs. Erector Spinae Plane Block in Endovascular Management of CLI
Comparison of popliteal sciatic nerve block and erector spinae plane block (ESPB) in patients undergoing endovascular management of critical lower limb ischemia (CLI).
- Conditions
- Critical Limb Ischemia (CLI), Popliteal Nerve Block, ESPB
- Trial name
- NCT06913348
- Testing
- Popliteal sciatic nerve block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Minia University Hospital
Regional Anesthesia, Local Anesthetic
Mixed Local for Sciatic Block
Choice of local anesthetics is the major determinant of the characteristics of a peripheral nerve block. Short acting local anesthetics while provides faster onset suffer from shorter duration.
- Trial name
- NCT06671028
- Testing
- Ropivacaine and Lidocaine, Ropivacaine 0,5%
- Volunteers
- 110 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Other Surgical Procedures
Ultrasound Guided Distal Sciatic Nerve Block - a Comparison With Nerve Stimulator Technique
For distal sciatic nerve block this prospective, randomised comparison with ultrasound guided distal subepineural block tested the hypothesis, that intraepineural injection of local anesthetic using nerve stimulation technique is…
- Trial name
- NCT01643616
- Testing
- midazolam, Prilocaine 1%, Ropivacaine 0.75%
- Volunteers
- 250 people
- Sponsor
- Helios Research Center
Phantom Limb Pain
Pre-emptive Sciatic Bloc to Prevent Lower Limb Phantom Pain
Phantom limb pain is a complication of amputation. Although pre-empitve epidural analgesia was once thought to prevent such a com plication, recent studies did not demonstrate this.
- Trial name
- NCT00528463
- Testing
- sciatic nerve block
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- Université de Sherbrooke