Clinical trials: Sciatic Pain
Piriformis Syndrome
Comparative Effects of PIR and PFS on Pain, Hip ROM, and Disability in Piriformis Syndrome
This randomized clinical trial evaluates the effectiveness of Post-Isometric Relaxation (PIR) and Post-Facilitation Stretching (PFS) for managing pain, improving hip abduction and internal rotation, and enhancing functional…
- Trial name
- PIR-PFS RCT (NCT07255053)
- Testing
- Post Isometric Relaxation (PIR), Post Facilitation Stretching (PFS)
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Faisalabad
Sciatica, Chronic Sciatica
Effects of Shockwave Therapy Versus Ultrasound Therapy Among Patients With Chronic Sciatica
Sciatica is characterized by radiating pain, functional limitations, reduced flexibility, disturbed sleep, and impaired quality of life.
- Conditions
- Sciatica, Chronic Sciatica, Lumbar Radiculopathy
- Trial name
- NCT07710924
- Testing
- Extracorporeal Shockwave Therapy, Therapeutic Ultrasound, Conventional Physiotherapy
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- University of Lahore
Ankle Ligament Injury，Chronic Ankle Instability，Ankle Arthroscopy
Preop US-Guided Nerve Blocks for Pain & Recovery After Ankle Arthroscopy
This randomized, double-blind controlled trial investigates the effectiveness and potential trade-offs of preoperative ultrasound-guided popliteal sciatic and saphenous nerve blocks in patients undergoing ankle arthroscopy, a…
- Trial name
- NCT07470021
- Testing
- Ultrasound-guided popliteal sciatic and saphenous nerve block
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Sciatica, Electroacupuncture
Effectiveness of Electro-acupuncture and Manual Therapy on Pain and Fucntion in Patients With Sciatica
The aims of the study are: To study the pain efficacy of an electroacupuncture and manual therapy protocol versus the use of manual therapy in patients with sciatica.
- Conditions
- Sciatica, Electroacupuncture, Manual Therapy
- Trial name
- NCT04764890
- Testing
- Electroacupuncture, Manual therapy
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- CEU San Pablo University
Piriformis Syndrome, Musculoskeletal Abnormalities
Comparing Two Soft Tissues Technique on Piriformis Syndrome Patients
Piriformis Syndrome is a neuromuscular condition with symptoms of pain, numbness and tingling tracing the route of the sciatic nerve, due to the nerve impingement by the piriformis muscle.
- Conditions
- Piriformis Syndrome, Musculoskeletal Abnormalities, Sciatica
- Trial name
- MPR-PIR (NCT07661485)
- Testing
- Myofascial Release, Post Isometric Relaxation
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- University of Faisalabad
Post Operative Pain
Ketamine and Dexmedetomidine Comparative Study
In this study, the investigators will compare the effect of adding ketamine and dexmedetomidine to bupivacaine in US-guided combined sciatic and femoral nerve blocks as regards the onset and duration of the block, postoperative…
- Trial name
- NCT06032624
- Testing
- combined ultra-sound guided femoral and sciatic nerve block.
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Popliteal Nerve Block, Foot Surgery
Continuous Popliteal Nerve Blocks: Effect of Perineural Catheter Tip Location Relative to the Sciatic Nerve Bifurcation on Postoperative Analgesia
Research study to determine the relationship between perineural catheter tip location relative to the sciatic nerve bifurcation and postoperative analgesia for continuous popliteal nerve blocks.
- Conditions
- Popliteal Nerve Block, Foot Surgery, Ankle Surgery, Popliteal Bifurcation
- Trial name
- NCT01229696
- Testing
- Catheter Placed At Bifurcation, Catheter Placed 5cm Above Bifurcation
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of California, San Diego
Lumbar Radiculopathy
Effect of High Versus Low-level Laser Therapy in Patients of Lumber Radiculopathy
To Compare the effects of high-level laser therapy (HLLT) and low-level laser therapy (LLLT) on pain in patients with lumbar radiculopathy.
- Trial name
- NCT06240845
- Testing
- High-level laser therapy, Low-level laser therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Sciatica
Evaluate the Safety, Tolerability and Pharmacokinetics of BG00010 (Neublastin) Administered to Sciatica Participants
The primary objective of the study is to determine the safety/tolerability profile, systemic PK behavior, and immunogenicity of single IV and SC administrations of BG00010 to sciatica participants.
- Trial name
- NCT00961766
- Testing
- BG00010 (Neublastin)
- Where
- Australia
- Volunteers
- 48 people
- Sponsor
- Biogen
Piriformis Muscle Syndrome, Myofacial Pain Syndromes
The Importance of Gluteus Maximus Muscle in Patients With Preliminary Diagnosis of Piriformis Syndrome
Literature shows different pathologies or combination pathologies can cause gluteal region pain and it can be difficult to diagnose.
- Conditions
- Piriformis Muscle Syndrome, Myofacial Pain Syndromes, Piriformis Syndrome
- Trial name
- NCT05271071
- Testing
- Ultrasound guided piriformis muscle and gluteus maximus muscle lidocaine injection
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Radiculopathy, Radiculopathy Lumbar
Mirror Image Spine Correction Exercises Versus Conservative Physiotherapy for Lumbar Radiculopathy
Lumbar radiculopathy is a common condition caused by irritation or compression of a lumbar nerve root, often resulting in radiating leg pain, numbness, weakness, and functional limitation.
- Conditions
- Radiculopathy, Radiculopathy Lumbar, Sciatica, Disc Disease Lumbar
- Trial name
- MIRROR-LR (NCT07558993)
- Testing
- Mirror Image Spine Correction Exercises, Conservative Physiotherapy
- Where
- United Arab Emirates
- Volunteers
- 64 people
- Sponsor
- University of Sharjah
Piriformis Syndrome
Comparative Effects of Stecco-fascial Manipulation and Rolfing Structural Integration in Patients With Piriformis Syndrome
This study aims to compare the effectiveness of Stecco Fascial Manipulation and Rolfing Structural Integration in treating Piriformis syndrome, focusing on special outcomes like pain severity and functional outcomes.
- Trial name
- Piriformis (NCT07322185)
- Testing
- Experimental: GROUP A ( Stecco fascial Manipulation), Experimental: GROUP B (Rolfing Structural Integration)
- Where
- 3 sites in Pakistan
- Volunteers
- 42 people
- Sponsor
- Danyal Ahmad
Sciatica
The Efficacy of Active Conservative Treatment for Patients With Severe Sciatica. A Randomized Clinical Controlled Trial
This Study si designed as a Prospective clinical controlled randomized trial. Background: Reviews have demonstrated no or little efficacy for passive conservative treatment modalities for patients suffering from sciatica.
- Trial name
- NCT00246948
- Testing
- Active conservative treatment of sciatica
- Where
- Denmark
- Volunteers
- 181 people
- Sponsor
- The Back Research Center, Denmark
Diabetic Foot
Sciatic Nerve Blocks With or Without Femoral Block Versus Spinal Anaesthesia in Patients Undergoing Diabetic Foot Surgery
Background: Dysautonomia refers to the abnormal function of the autonomic nervous system including sympathetic and parasympathetic nervous system. Diabetes mellitus causes secondary dysautonomias (1).
- Trial name
- NCT02727348
- Testing
- Sciatic with or without femoral block, Spinal anaesthesia
- Where
- Malaysia
- Volunteers
- 120 people
- Sponsor
- University of Malaya
Low Back Pain, Sciatica
Non-surgical Spinal Decompression in Patients With Chronic Low Back Pain
The goal of this quasi-experimental trial was to evaluate the effects of non-surgical spinal decompression on disability and pain in patients with chronic low back pain and sciatica throughout a two-month follow-up, and to…
- Conditions
- Low Back Pain, Sciatica, Lumbar Disc Herniation
- Trial name
- NCT06275750
- Testing
- Spinal decompression with BTL-6000 spinal decompression system (BTL Industries Ltd.)
- Where
- Mexico
- Volunteers
- 39 people
- Sponsor
- Hospital Civil de Guadalajara
Neuropathic Pain, Sciatic Pain
Ginger Root Extract for Sciatic Pain Individuals
Neuropathic pain affects the quality of life of many Americans. Non-pharmacological strategies such as bioactive compounds in foods are being explored as therapeutics but can also serve as tools to better understand pain…
- Trial name
- Ginger-NP (NCT06817018)
- Testing
- Ginger
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Leslie Shen
Orthopedic Surgical Procedures, Postoperative Pain
Duration of Sciatic Nerve Block After Injection of Local Anesthetic In or Around the Nerve
This study was designed to assess whether the injection of local anesthetic into the nerve (intraneural), as opposed to around it (perineural), leads to longer anesthesia and analgesia of the leg.
- Trial name
- NCT01981291
- Testing
- Intraneural Injection for Subgluteal Sciatic Nerve Block, Perineural Injection for Subgluteal Sciatic Nerve Block, Femoral Nerve Block
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- University of Parma
Pelvic Pain Syndrome, Sacroiliac Disorder
Chronic Pelvic Pain in Females and Males
Pelvic pain is under-reported in healthy adults. Many patients with pelvic pain under-estimate the problem. Chronic pelvic pain can be managed properly, if diagnosed promptly.
- Conditions
- Pelvic Pain Syndrome, Sacroiliac Disorder, Piriformis Syndrome, Sacrococcygeal Disorder
- Trial name
- NCT06102733
- Testing
- Rehabilitation therapy
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Salem Anaesthesia Pain Clinic
Piriformis Syndrome
Foam Rolling and Dynamic Stretching in Piriformis Syndrome
To compare the combined effects of foam rolling and dynamic stretching in patients with piriformis syndrome. 1. Warm-Up (2-3 minutes) Objective: Increase blood flow and prepare muscles for stretching.
- Trial name
- NCT07278193
- Testing
- Group A (Foam Rolling), Group B (Foam rolling and Dynamic Stretching)
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- University of Lahore
Complex Regional Pain Syndromes, Fibromyalgia
Virtual Environment Rehabilitation for Patients With Motor Neglect Trial
Motor neglect describes a loss of function without a loss of strength, reflexes or sensation. Motor neglect has been described in patients with traumatic brain injury, stroke and chronic pain conditions, e.g.
- Conditions
- Complex Regional Pain Syndromes, Fibromyalgia, Stroke, Traumatic Brain Injury
- Trial name
- VERMONT (NCT03887962)
- Testing
- Virtual Environment Biofeedback, Treadmill walking with no Virtual Environment Biofeedback
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust