Clinical trials: Screening Colonoscopy
Adenoma Colon
Effect of Water Exchange Plus Acetic Acid Staining on the Detection of Flat Polyps During Colonoscopy
Our previous study (Am. J. Gastroenterol. 2017 04;112(4)) showed that water exchange (WE) colonoscopy was able to increase the detection of flat adenomas as well as overall ADR.
- Trial name
- NCT04464135
- Testing
- acetic acid staining, Water exchange colonoscopy
- Where
- 4 sites in China
- Volunteers
- 300 people
- Sponsor
- Air Force Military Medical University, China
Colon Cancer
Vitamin D and Screening Colonoscopy or Polyp Surveillance
The investigators will recruit DoD beneficiaries 18 years or older, that have been referred for a screening colonoscopy or polyp surveillance (or had one in the last 2 weeks), and have no previous diagnosis of colorectal cancer.
- Trial name
- VitDColon (NCT02269332)
- Testing
- Screening Colonoscopy
- Where
- United States
- Volunteers
- 298 people
- Sponsor
- Mike O'Callaghan Military Hospital
Nitrous Oxide
Colonoscopy Using Nitrous Oxide- A Pilot Study in the USA
Colon cancer is the second most common cancer in men and the third most common cancer in women worldwide. The clinical objectives of administering sedation for GI endoscopy are to relieve patient anxiety and discomfort and to…
- Trial name
- NCT04305158
- Testing
- Nitrous Oxide
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Colon Cancer
The Efficiency of Colon Capsule Endoscopy in Colon Cancer Screening
Main objective is to improve colorectal cancer (CRC) screening programme in the Czech Republic and decrease the disease incidence and mortality.
- Trial name
- NCT03052335
- Testing
- Pillcam® COLON 2 Capsule, Colonoscopy
- Where
- Czechia
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Military University Hospital, Prague
Natural Killer Cell Cytokine Production
Measurement of NK Cell Activity in Whole Blood in Subjects Being Screened for Colorectal Cancer Using Colonoscopy
This study will look at measuring the activity of natural killer (NK) cells using the in vitro diagnostic device NK Vue in subjects being screened for colorectal cancer using colonoscopy.
- Trial name
- NCT02291198
- Testing
- NK Vue: NK cell activity in stimulated whole blood
- Where
- Canada
- Volunteers
- 1,081 people, healthy volunteers welcome
- Sponsor
- ATGen Canada Inc
Colorectal Cancer
Feasibility of Reduction in Right Sided Bowel Cancer Through Contrast Enhanced Colonoscopy
The Bowel Cancer Screening program was implemented to address the important issue of prevention and early detection of bowel cancer.
- Trial name
- CONSCOP (NCT01972451)
- Testing
- Colonoscopy with enhanced dye
- Where
- United Kingdom
- Volunteers
- 1,320 people
- Sponsor
- Lisette Nixon
Cancer Colorectal
Effectiveness and Safety of the Colonoscopy Assisted by Endocuff vs. Standard in the Colorectal Cancer Screening
The hypothesis of the present study is to demonstrate that ENDOCUFF VISION® increases the detection rate of adenomas thanks to the improved visibility produced by the retraction of the folds and stabilizing the colonoscope.
- Trial name
- NCT04280393
- Testing
- Colonoscopy procedure with endocuff
- Where
- Spain
- Volunteers
- 822 people
- Sponsor
- Hospital Provincial de Castellon
Colonoscopy
HyGIeaCare Prep vs Split-dose PEG Prep Prior to Colonoscopy
The purpose of this study is to compare the level of cleanliness using the HyGIeaCare Prep vs the standard of care Split-dose PEG prep used prior to colonoscopy.
- Trial name
- NCT02893748
- Testing
- HyGIeaCare Prep, Colonoscopy, polyethylene glycol (PEG)
- Volunteers
- healthy volunteers welcome
- Sponsor
- HyGIeaCare, Inc.
Colorectal Polyp, Colorectal Cancer
Computer-aided Detection During Screening Colonoscopy
Nowadays, colonoscopy is considered the gold standard for the detection of lesions in the colorectal mucosa. However, around 25% of polyps may be missed during the conventional colonoscopy.
- Conditions
- Colorectal Polyp, Colorectal Cancer, Colorectal Adenoma
- Trial name
- NCT05734820
- Testing
- HD- colonoscopy, HD-colonoscopy assisted by AI
- Where
- Ecuador
- Volunteers
- 312 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Colorectal Cancer Screening
Colon Capsule Endoscopy (CCE) Versus Computed Tomographic Colonography (CTC) in the Identification of Colonic Polyps in a Screening Population.
The primary objective of this multicenter, prospective, randomized study is to assess the diagnostic yield of Colon Capsule Endoscopy (CCE) versus Computed Tomographic Colonography (CTC) in a screening population.
- Trial name
- TOPAZ (NCT02754661)
- Testing
- COLON Capsule endoscopy, Computed Tomographic Colonography
- Where
- 13 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Colonoscopy
Impact of Digital Tools on the Quality of Bowel Preparation for Colonoscopy
This is a single blinded randomized controlled study. The main question of this study is whether better preparation by making full use of digital tools can increase patient compliance with the preparation methods for colonoscopy…
- Trial name
- NCT05734079
- Testing
- Standard of care, Standard of care + Video call, Standard of care + Video call + Educational video film
- Volunteers
- 825 people, healthy volunteers welcome
- Sponsor
- Ziv Hospital
Colon Cancer, Rectum Cancer
Efficacy of Colonoscopy, Colon Capsule and Fecal Immunological Test for Colorectal Cancer Screening
Efficacy of colonoscopy, colon capsule and fecal immunological test for colorectal cancer screening, in first degree relatives of patients with colorectal neoplasia: a prospective randomized study.
- Trial name
- FAMCAP (NCT02738359)
- Testing
- optical colonoscopy, colon capsule endoscopy, fecal immunological test (FIT)
- Where
- 17 sites in France
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Hôpital Edouard Herriot
Screening Test, Endoscopy
The Alberta Primary Care Endoscopy (APC-Endo) Study
It is hypothesized that primary care colonoscopists are able to achieve benchmarks in colonoscopy quality including cecal intubation and adenoma detection rates and serious adverse event rates.
- Conditions
- Screening Test, Endoscopy, Colon Disease
- Trial name
- APC-Endo (NCT01320826)
- Testing
- colonoscopy
- Where
- 13 sites in Canada
- Volunteers
- 577 people
- Sponsor
- University of Alberta
Colon Cancer Screening
Impact of Chewing Gum on Bowel Preparation in Patients Undergoing Colonoscopy
Colorectal cancer is the second leading cause of cancer deaths that could be prevented in the United States. Colonoscopy is the best test for finding and removing polyps before they turn into cancer.
- Trial name
- NCT07320989
- Testing
- Chewing Sugar-Free Gum During Bowel Preparation, Standard Bowel Prep (2L PEG-ELP), Standard Bowel Prep
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Maryland, Baltimore
Colorectal Cancer
e-Motivación: Developing and Pilot Testing an App to Improve Latinos' Screening Colonoscopy Rates
Among Latinos, a fast growing and underserved population, Colorectal Cancer (CRC) is the third leading cause of cancer death in men and in women.
- Trial name
- NCT04987788
- Testing
- Motívate, Video link
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Colorectal Cancer
Interventions to Improve Colon Cancer Screening in Poor Rural Iowa Counties
The goal of the study is to conduct a randomized clinical trial to test several office-based strategies for improving colon cancer screening among individuals who are regular patients at 16 family practice physician offices in…
- Trial name
- NCT01477814
- Testing
- Physician chart reminder, chart reminder, educational mat'ls, FIT, CR,ed mat'ls, FIT, phone call
- Where
- United States
- Volunteers
- 743 people, healthy volunteers welcome
- Sponsor
- Barcey T. Levy
Inflammatory Bowel Diseases, Microbiota
Evaluation of the Diagnostic Potential of Artificial Intelligence-assisted Fecal Microbiome Testing for Inflammatory Bowel Disease
The goal of this clinical trial is to evaluate the diagnostic potential of Artificial Intelligence-assisted Fecal Microbiome Testing for the diagnosis of inflammatory bowel disease.
- Conditions
- Inflammatory Bowel Diseases, Microbiota, Colonoscopy
- Trial name
- NCT05797207
- Testing
- Artificial Intelligence-assisted Fecal Microbiome Testing, Colonoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Istanbul Medipol University Hospital
Colorectal Neoplasms Malignant, Colonoscopy
Sensitivity of Fecal Immunochemical Test (FIT) for Colorectal Cancer (CRC) Screening
Fecal immunochemical test (FIT) was introduced in France late 2015, FIT has better diagnostic accuracy for colorectal cancers (CRCs) than previous screening tests.
- Conditions
- Colorectal Neoplasms Malignant, Colonoscopy, Early Detection of Cancer, Female
- Trial name
- FITBACK (NCT05163236)
- Testing
- Positive fecal immunochemical test (FIT), Negative fecal immunochemical test (FIT), Fecal immunochemical test (FIT) not performed
- Where
- France
- Volunteers
- 1,149 people
- Sponsor
- University Hospital, Brest
Colorectal Neoplasm, Colonic Polyps
Clinical Study of Real Time Colorectal Polyp Diagnosis During Colonoscopy - the VALID Colonoscopy Study
The investigators hypothesize that high definition colonoscopy with close focus narrow band imaging features has a high diagnostic accuracy for colorectal polyp histology, and can replace formal pathologic assessment in cases of…
- Trial name
- VALID (NCT01288833)
- Testing
- Close focus HD NBI Colonoscopy System
- Where
- 2 sites in United States
- Volunteers
- 558 people, healthy volunteers welcome
- Sponsor
- VA Palo Alto Health Care System
Colonoscopy, Bowel Preparation Solutions
Electrolyte Beverage Combined With Polyethylene Glycol for Colonoscopy Bowel Preparation
This randomized controlled trial aims to evaluate the effects of different ratios of electrolyte beverage and water combined with polyethylene glycol (PEG) on bowel preparation quality before colonoscopy.
- Conditions
- Colonoscopy, Bowel Preparation Solutions, Colorectal Cancer Screening
- Trial name
- NCT07608120
- Testing
- PEG With Water, PEG With Low-dose Electrolyte Beverage, PEG With Medium-dose Electrolyte Beverage
- Where
- China
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University